• encode
  • Genes that encode for ion channels in bacteria can be utilized and altered in simple ways to provide human cells with the creation or enhancement of electrical signaling, an essential part of life's most fundamental processes. (labroots.com)
  • CRISPR
  • CRISPR, the superhero of gene editing, just got a little more super. (singularityhub.com)
  • In a trio of studies released last week in Science , leading CRISPR labs around the world unveiled some ultra-creative additions to the technique, transforming the hotshot editor into a virus detective or a sharp-eyed historian jotting down a cell's entire history into DNA. (singularityhub.com)
  • genetics
  • In the next generations, those alleles (one variety of a gene) would usually increase in frequency and lead to changes in population genetics (Prugnolle et al. (springer.com)
  • experiment
  • However, despite the enormous scientific importance of this work, which became known as the Avery-MacLeod-McCarty experiment, the trio did not win a Nobel Prize for their discovery. (wikipedia.org)
  • chromosome
  • A visual fluorescence analysis of chromosomes from MDS patients shows that deletions of PURA at 5q31 are more strongly linked to progression of MDS to AML when combined with deletions of the PURB gene, including complete loss of chromosome 7. (wikipedia.org)
  • protein
  • Following the identification of a Pur factor, which specifically bound a purine-rich sequence in the control region of the c-MYC gene, the gene, PURA, encoding the protein, Pur-alpha, was cloned and sequenced for both human and mouse (GenBank U02098.1). (wikipedia.org)
  • uses
  • US researcher Herb Boyer uses enzymes to cut DNA and splice it into bacterial plasmids, which then replicate producing many copies of the inserted gene. (newscientist.com)
  • brain
  • Studies of genetic inactivation of PURA in the mouse provided evidence leading to that for PURA gene disorders in brain disease. (wikipedia.org)
  • common
  • Because of evolutionary conservation, when organisms along the evolutionary tree share common features that are important, there are many similarities between the human and bacterial sodium ion channels. (labroots.com)
  • In 1941, Avery and MacLeod separated a crude extract from smooth ('S') strains of Streptococcus pneumoniae, the most common cause of bacterial pneumonia. (wikipedia.org)
  • responsible
  • In his early years as a research scientist, MacLeod, with Oswald Avery and Maclyn McCarty, demonstrated DNA is the molecule responsible for bacterial transformation - and in retrospect, the physical basis of the gene. (wikipedia.org)
  • changes
  • The altered glycosylation could be relevant in determining changes in the mucosa-associated bacterial flora. (bmj.com)
  • single
  • The aetiology of CD is more complex than the deletion of a single immunoregulatory gene. (bmj.com)
  • discovery
  • A growing body of evidence inspired by the discovery of zonulin suggests that a trio of factors underlies most, if not all autoimmune diseases. (paleoplan.com)