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  • CRISPR
  • CRISPR, the superhero of gene editing, just got a little more super. (singularityhub.com)
  • In a trio of studies released last week in Science , leading CRISPR labs around the world unveiled some ultra-creative additions to the technique, transforming the hotshot editor into a virus detective or a sharp-eyed historian jotting down a cell's entire history into DNA. (singularityhub.com)
  • genetics
  • In the next generations, those alleles (one variety of a gene) would usually increase in frequency and lead to changes in population genetics (Prugnolle et al. (springer.com)
  • genomes
  • And horizontal gene transfer is essential for explaining the new information from sequenced genomes, according to an informative NYT article. (panspermia.org)
  • genetic
  • They used genetic sequencing of bacterial DNA in fecal samples from adult Americans-either from those following a typical American diet or a diet restricted in calories but with sufficient nutrients-to identify unique gut microbial communities associated with these diets. (nih.gov)
  • Studies of genetic inactivation of PURA in the mouse provided evidence leading to that for PURA gene disorders in brain disease. (wikipedia.org)
  • experiment
  • However, despite the enormous scientific importance of this work, which became known as the Avery-MacLeod-McCarty experiment, the trio did not win a Nobel Prize for their discovery. (wikipedia.org)
  • chromosome
  • A visual fluorescence analysis of chromosomes from MDS patients shows that deletions of PURA at 5q31 are more strongly linked to progression of MDS to AML when combined with deletions of the PURB gene, including complete loss of chromosome 7. (wikipedia.org)
  • protein
  • Following the identification of a Pur factor, which specifically bound a purine-rich sequence in the control region of the c-MYC gene, the gene, PURA, encoding the protein, Pur-alpha, was cloned and sequenced for both human and mouse (GenBank U02098.1). (wikipedia.org)
  • human
  • Because of evolutionary conservation, when organisms along the evolutionary tree share common features that are important, there are many similarities between the human and bacterial sodium ion channels. (labroots.com)
  • Human Pur-alpha contains three repeats of this Pur domain and bacterial Pur-alpha contains one. (wikipedia.org)
  • smaller
  • Publishing their results in Nature Communications, the researchers maneuvered around that barrier by engineering ion channels from bacterial genes, which are smaller. (labroots.com)
  • uses
  • US researcher Herb Boyer uses enzymes to cut DNA and splice it into bacterial plasmids, which then replicate producing many copies of the inserted gene. (newscientist.com)
  • changes
  • The altered glycosylation could be relevant in determining changes in the mucosa-associated bacterial flora. (bmj.com)
  • common
  • In 1941, Avery and MacLeod separated a crude extract from smooth ('S') strains of Streptococcus pneumoniae, the most common cause of bacterial pneumonia. (wikipedia.org)
  • responsible
  • In his early years as a research scientist, MacLeod, with Oswald Avery and Maclyn McCarty, demonstrated DNA is the molecule responsible for bacterial transformation - and in retrospect, the physical basis of the gene. (wikipedia.org)
  • single
  • The aetiology of CD is more complex than the deletion of a single immunoregulatory gene. (bmj.com)
  • discovery
  • A growing body of evidence inspired by the discovery of zonulin suggests that a trio of factors underlies most, if not all autoimmune diseases. (paleoplan.com)