• Cl3CCH
  • 4 Cl2 + C2H5OH + H2O → Cl3CCH(OH)2 + 5 HCl Chloral hydrate is metabolized in vivo to trichloroethanol, which is responsible for its physiological and psychological effects. (wikipedia.org)
  • This reaction is catalyzed by antimony trichloride: H3CCHO + 3 Cl2 + H2O → Cl3CCH(OH)2 + 3 HCl The chloral hydrate is distilled from the reaction mixture. (wikipedia.org)
  • For this purpose, chloral is treated with chlorobenzene in the presence of a catalytic amount of sulfuric acid: Cl3CCHO + 2 C6H5Cl → Cl3CCH(C6H4Cl)2 + H2O This reaction was described by Othmar Zeidler in 1874. (wikipedia.org)