• Attacks occurring before puberty or after age 40 years are unusual unless a major provocation, such as new use of phenobarbital or estrogens, had occurred. (medscape.com)
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  • 58% women) with confirmed insomnia disorder and no major depression within the previous 12 months found CBT significantly reduced risk of depression in patients with insomnia. (medscape.com)
  • Neither chloral hydrate not L-tryptophan had any significant side effects, but withdrawal of chloral hydrate was associated with insomnia. (nih.gov)
  • The effects of placebo, L-tryptophan 3 g, and chloral hydrate 500 mg on sleep were studied in 19 nonpsychotic, mildly demented, geriatric inpatients. (nih.gov)
  • GABA A receptors including those of the ρ-subclass are ligand-gated ion channels responsible for mediating the effects of gamma-amino butyric acid (GABA), the major inhibitory neurotransmitter in the brain. (wikimili.com)