• Triatomine bugs are responsible for the transmission of a trypanosome, Trypanosoma cruzi, which causes Chagas disease. (wikipedia.org)
  • California based biopharmaceutical company, KaloBios Pharmaceuticals, Inc. yesterday announced positive guidance in the minutes from a recent meeting with the U.S. Food and Drug Administration (FDA) to discuss the development plans for benznidazole for the treatment of Chagas disease, a neglected tropical disease. (outbreaknewstoday.com)
  • According to the Centers for Disease Control and Prevention (CDC), an estimated 300,000 people in the United States are infected with Chagas disease, which, if left untreated, can lead to serious and potentially life-threatening cardiovascular, gastro-intestinal and neurological complications. (outbreaknewstoday.com)
  • Benznidazole is the current preferred treatment for Chagas disease in other parts of the world but is not currently approved by the FDA in the U.S. (outbreaknewstoday.com)
  • If approved as a treatment for Chagas, benznidazole is currently expected to be eligible for a priority review voucher (PRV), awarded to sponsors of certain treatments for neglected tropical diseases that meet criteria specified by the Federal Food, Drug, and Cosmetic (FD&C) Act. (outbreaknewstoday.com)
  • This guidance makes it clear that we are on the right track with our development of benznidazole for Chagas disease, and we expect we will progress expeditiously toward a submission," said Cameron Durrant, MD, KaloBios chairman and CEO. (outbreaknewstoday.com)
  • However, in several areas of the United States Chagas is ever present, according to Dr. Peter Hotez, founding dean of the National School of Tropical Medicine at Baylor College of Medicine, who told me in 2013 the number of cases of Chagas disease in the United States to be somewhere between 300,000 and 1 million. (outbreaknewstoday.com)
  • In Texas, approximately 45% of the collected triatomine bugs have tested positive for T. cruzi, and Chagas is considered an endemic disease in dogs. (outbreaknewstoday.com)
  • From 2013 to 2014, 351 cases of Chagas disease in animals, primarily dogs, were reported from approximately 20% of Texas counties, representing all geographic regions of the state. (outbreaknewstoday.com)
  • From 2013 to 2014, 39 human cases of Chagas disease were reported: 24 were acquired in another country, 12 were locally-acquired, and the location of acquisition was unknown for 3. (outbreaknewstoday.com)
  • Chagas disease is transmitted naturally in North, Central, and South America. (outbreaknewstoday.com)
  • In parts of Mexico and Central and South America, where Chagas disease is considered highly endemic, it is estimated that approximately 8 million people are infected. (outbreaknewstoday.com)
  • T. cruzi is a comma shaped flagellated parasite and the cause of an acute and chronic disease called Chagas. (outbreaknewstoday.com)
  • There is also concerted action to eliminate other major diseases that affect millions, such as malaria and Chagas disease. (rentokil.com)
  • Several articles, recent to early 2014, warn that human activities are spreading vector-borne zoonotic diseases. (wikipedia.org)
  • Examples of vector-borne zoonotic diseases include: Lyme disease Plague West Nile virus Many factors affect the incidence of vector-borne diseases. (wikipedia.org)
  • Airborne disease Asymptomatic carrier Fomite Globalization and disease Insect vectors of human pathogens Insect vectors of plant pathogens VectorBase: genomic database of invertebrate vectors of human pathogens List of diseases caused by insects Natural reservoir Waterborne disease 2007 Yap Islands Zika virus outbreak "Vector-borne zoonotic diseases are those that naturally infect wildlife and are then transmitted to humans through carriers, or vectors, such as mosquitoes or ticks. (wikipedia.org)
  • Taken together, our results demonstrate the utility of zoos as sentinels for emerging pathogens, for studying wildlife and human risk of zoonotic diseases, and for assessing vector diversity. (bvsalud.org)
  • Snakeborne Armillifer pentastomiasis is an emerging human parasitic infection in rural tropical areas where snake meat is eaten. (cdc.gov)
  • Benznidazole and nifurtimox are 100 percent effective in killing the parasite and curing the disease, but only if given soon after infection at the onset of the acute phase, according to the WHO. (outbreaknewstoday.com)
  • 1. As Nurse Thomas took care of a patient recently returned from an African safari and showing signs of parasitic infection, he pondered over the role of the tsetse fly in disease transmission. (rnpedia.com)
  • [1] An infectious disease , also known as a transmissible disease or communicable disease , is an illness resulting from an infection. (wikipedia.org)
  • The signs and symptoms of an infection depend on the type of disease. (wikipedia.org)
  • An infection is not synonymous with an infectious disease, as some infections do not cause illness in a host. (wikipedia.org)
  • In certain cases, infectious diseases may be asymptomatic for much or even all of their course in a given host. (wikipedia.org)
  • In the latter case, the disease may only be defined as a "disease" (which by definition means an illness) in hosts who secondarily become ill after contact with an asymptomatic carrier . (wikipedia.org)
  • This disease is endemic in certain regions of sub-Saharan Africa. (rnpedia.com)
  • With concerted action by the international community, some diseases endemic in developing countries have been drastically reduced. (rentokil.com)
  • Humans can also be vectors for some diseases, such as Tobacco mosaic virus, physically transmitting the virus with their hands from plant to plant. (wikipedia.org)
  • It is also theoretically possible to 'eliminate' a disease in humans while the microbe remains at large, as in the case of neonatal tetanus, for which the World Health Organization (WHO) in 1989 declared a goal of global elimination by 1995. (cdc.gov)
  • Zoos provide a unique opportunity to study mosquito feeding ecology as they represent areas where exotic animals, free-roaming native animals, humans, and mosquito habitats overlap. (bvsalud.org)
  • This pathogen is a parasitic protozoan that is transmitted by the bite of an infected tsetse fly. (rnpedia.com)
  • Consider the disease that is often associated with ticks, and the bacteria that actually causes it. (rnpedia.com)
  • 2. Nurse Oliver is preparing educational materials on the relationship between specific diseases and their causative bacteria. (rnpedia.com)
  • Emerging Infectious Diseases , 22 (8), 1333-1339. (cdc.gov)
  • Emerging Infectious Diseases , 22 (8), 1340-1347. (cdc.gov)
  • Outbreak News Today is an online blog magazine which focuses on news and information about infectious diseases and outbreaks. (outbreaknewstoday.com)
  • Multidisciplinary field focusing on prevention of infectious diseases and patient safety during international TRAVEL. (lookformedical.com)
  • Infectious disease" redirects here. (wikipedia.org)
  • For the medical specialty, see Infectious diseases (medical specialty) . (wikipedia.org)
  • For the journal, see Infectious Disease (journal) . (wikipedia.org)
  • Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). (wikipedia.org)
  • [4] The branch of medicine that focuses on infections is referred to as infectious diseases . (wikipedia.org)
  • The first major discovery of a disease vector came from Ronald Ross in 1897, who discovered the malaria pathogen when he dissected a mosquito. (wikipedia.org)
  • Malaria in ANIMALS is caused by other species of plasmodia. (lookformedical.com)
  • Tick species and associated pathogens are expanding into new areas, shifting threats to human, and animal health across the state. (bvsalud.org)
  • Macroparasites [9] ( worms or helminths ) including nematodes such as parasitic roundworms and pinworms , tapeworms (cestodes), and flukes ( trematodes , such as schistosomes ). (wikipedia.org)
  • citation needed] The World Health Organization (WHO) states that control and prevention of vector-borne diseases are emphasizing "Integrated Vector Management (IVM)", which is an approach that looks at the links between health and environment, optimizing benefits to both. (wikipedia.org)
  • It is estimated that over 80% of the world's population resides in areas under threat of at least one vector borne disease. (wikipedia.org)
  • To address this growing need, the Northeast Regional Center for Excellence in Vector-Borne Diseases (NEVBD) designed a unique educational program to cross-train students in the fundamentals of vector biology and public health. (bvsalud.org)
  • Here, we summarize the formation, evaluation, and outcomes of NEVBD's Master of Science in Entomology: Vector-Borne Disease Biology program and provide details on core competencies to enable adoption and adaptation of the program to other institutions and contexts. (bvsalud.org)
  • The Tiger Mosquito, Aedes albopictus , for example, is a prolific breeder in man-made environments and a vector for several diseases including dengue, West Nile fever and Japanese encephalitis. (rentokil.com)
  • It is one of several vector species being monitored by the VectorNet project of the European Centre for Disease Prevention and Control. (rentokil.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • Think of the tsetse fly as a courier that delivers a harmful package (the T. gambiense parasite) from one location (an infected human or animal) to another (a non-infected human). (rnpedia.com)
  • An important part of the work was to help identify key impediments to improved prevention and control of the diseases under discussion, even if the disease was not considered to have potential as a candidate for eradication. (cdc.gov)
  • The ITFDE defined eradication as 'reduction of the worldwide incidence of a disease to zero as a result of deliberate efforts, obviating the necessity for further control measures. (cdc.gov)
  • Between the extremes of disease 'control' (reduction in incidence and/or prevalence) and 'eradication,' several intermediate levels of impact on diseases may be described. (cdc.gov)
  • Sudden increase in the incidence of a disease. (lookformedical.com)
  • Ticks and tick-borne diseases are an immense public health burden in New York State (NYS), United States. (bvsalud.org)
  • Arthropods such as ticks , mites , fleas , and lice , can also cause human disease, which conceptually are similar to infections, but invasion of a human or animal body by these macroparasites is usually termed infestation . (wikipedia.org)
  • The Triatomine bugs defecate during feeding and the excrement contains the parasites, which are accidentally smeared into the open wound by the host responding to pain and irritation from the bite. (wikipedia.org)
  • Insect-borne diseases impose immense health and economic burdens on both individuals and nations. (rentokil.com)
  • Any warm-blooded animal can carry rabies, but the most common vectors are dogs, skunks, raccoons, and bats. (wikipedia.org)
  • Eliminating transmission of a disease may also be considered, as in the case of yaws, the late noninfectious clinical manifestations remain of which but are not a danger to others. (cdc.gov)
  • Programs of surveillance designed to prevent the transmission of disease by any means from person to person or from animal to man. (lookformedical.com)
  • Therefore, these locations are a concern for arbovirus transmission to both valuable zoo animals and human visitors. (bvsalud.org)
  • The successful eradication of smallpox in 1977 and the ongoing campaigns to eradicate dracunculiasis by 1995 and poliomyelitis by 2000 should ensure that eradication of selected diseases will continue to be used as a powerful tool of international public health. (cdc.gov)
  • Aspects of health and disease related to travel. (lookformedical.com)
  • Eventually, however, the disease was shown to be viral. (wikipedia.org)
  • It also concluded that manifestations of seven other diseases could be 'eliminated,' and it noted critical research needs that, if realized, might permit other diseases to be eradicated eventually. (cdc.gov)
  • These factors include animals hosting the disease, vectors, and people. (wikipedia.org)
  • Rabies is transmitted through exposure to the saliva or brain tissue of an infected animal. (wikipedia.org)
  • Diseases returned to epidemic proportions and required multi-agency collaboration in the international community to restart control programmes. (rentokil.com)
  • The WHO estimates that 310 million people are at risk of this disease. (rentokil.com)
  • The tsetse fly becomes infected with T. gambiense when it bites an infected human or animal. (rnpedia.com)
  • Some diseases are being seen in places previously separated from the vectors by physical and climatic boundaries as vectors that are carried around the world through trade, migration and travel, gain a foothold in new locations. (rentokil.com)
  • This report summarizes the conclusions of the International Task Force for Disease Eradication (ITFDE), a group of scientists who were convened by a secretariat at the Carter Center of Emory University six times during 1989-1992. (cdc.gov)
  • This issue of MMWR Recommendations and Reports consolidates the deliberations of the International Task Force for Disease Eradication (ITFDE), which was convened six times from 1989 through 1992 to evaluate diseases as potential candidates for global eradication (1-7). (cdc.gov)
  • The purpose of the ITFDE was to establish criteria and apply them systematically to evaluate the potential eradicability of other diseases in the aftermath of the Smallpox Eradication Program. (cdc.gov)
  • The names of the members of the ITFDE, the criteria they developed and used, and summaries of the papers that were presented to the ITFDE by various experts are included in this report, as well as a brief history of the concept of disease eradication since the late 19th century. (cdc.gov)
  • The science dealing with the earth and its life, especially the description of land, sea, and air and the distribution of plant and animal life, including humanity and human industries with reference to the mutual relations of these elements. (lookformedical.com)
  • For example, the big-vein disease of lettuce was long thought to be caused by a member of the fungal division Chytridiomycota, namely Olpidium brassicae. (wikipedia.org)