• Kartagener described the syndrome, the Kartagener syndrome, in 1933, as a triad of chronic sinusitis, bronchiectasis and situs inversus. (wikipedia.org)
  • This is now known as primary ciliary dyskinesia (the Siewert-Kartagener syndrome), and the situs inversus occurs in about half of the patients. (wikipedia.org)
  • M. Kartagener und P. Stucki: Bronchiectasis with situs inversus. (wikipedia.org)
  • Situs inversus, bronchiectasis, and sinusitis and its relation to immotile cilia: history of the diseases and their discoverers - Manes Kartagener and Bjorn Afzelius Pediatr Radiol (2004) 34: 38-42 DOI 10.1007/s00247-003-1072-9 '(Ueber einen Fall von Kankroid der Schilddrüse mit peritheliomartigen Bildern)' https://litfl.com/manes-kartagener/ W. Löffler und M. Kartagener: Die konzentration der Faeces und Ihre Bedeutung für den Säure-basenhaushalt. (wikipedia.org)
  • Kartagener's syndrome is a rare, autosomal recessive inherited disease, which is characterized by a triad of chronic sinusitis, bronchiectasis, and situs inversus. (e-jer.org)
  • The triad of situs inversus, bronchiectasis, and chronic sinusitis became known as Kartagener's syndrome. (e-jer.org)
  • The patient had a past medical history of chronic sinusitis, bronchiectasis, and situs inversus totalis. (e-jer.org)
  • recessive disorder consisting of the triad of Approximately 50 % of patients with SCD sinusitis, bronchiectasis and situs inversus with have laterality defects (including situs inversus dextrocardia and represents a subgroup of totalis and, less frequently, heterotaxy and primary ciliary dyskinesia (PCD). (bvsalud.org)
  • Defects of cilia and flagella are manifested in the syndrome of immovable cilia (nl), the development of recurrent chronic bronchitis and sinusitis is likely. (medprep.info)
  • This leads to recurrent or persistent respiratory infections, sinusitis , otitis media , and male infertility. (medscape.com)
  • Cystic fibrosis (CF) is a chronic, multisystem disorder characterized by recurrent endobronchial infections, progressive obstructive pulmonary disease, and pancreatic insufficiency with intestinal malabsorption. (medscape.com)
  • In this report, we aimed to represent the effect of aerobic exercise training in addition to chest physiotherapy in an outpatient with Kartagener's syndrome. (e-jer.org)
  • An 18-year-old female diagnosed with Kartagener's syndrome applied with the complaints of productive cough and dyspnea with exertion and attended pulmonary rehabilitation program comprising exercise training in addition to standard treatment. (e-jer.org)
  • We recommend exercise training in patients with Kartagener's syndrome to increase exercise capacity. (e-jer.org)
  • There is no randomized study in the treatment of primary ciliary dyskinesia/Kartagener's syndrome. (e-jer.org)
  • An 18-year-old female Kartagener's syndrome diagnosed patient presented to our outpatient department with the complaints of chronic productive cough and progressive dyspnea with exertion. (e-jer.org)
  • More than half of patients with a similar syndrome have situs viscerus inversus - transposition of internal organs (heart on the right, liver on the left, etc.), which together constitute Kartagener's syndrome (*244400, 14q32, DNECL gene [600112, dynein heavy chain], p ).Clinical characteristics. (medprep.info)
  • With Kartagener's syndrome and immovable cilia syndrome, women are fertile. (medprep.info)
  • of Kartagener's syndrome. (bvsalud.org)
  • Facial evaluation may reveal a widened nasal bridge due to chronic polyposis. (medscape.com)
  • Samter's triad is a major symptom which is characterized by worsened asthma, skin rash and persistent nasal polyps and experienced as a major symptom in those patients suffering from nasal polyps along aspirin intolerance. (healthncare.info)
  • Chronic sinusitis seems closely associated with endobronchial bacterial infections and appears to impact pulmonary reactivity and chronicity of disease within the sinobronchial tract. (medscape.com)
  • Clinically symptomatic sinusitis, as evidenced by pain, discharge, fever, or postnasal drip, is found in only about 10% of patients with cystic fibrosis. (medscape.com)
  • This phenomenon may represent a truly asymptomatic disease state, or it may suggest that patients with this chronic disease have psychologically adapted to their symptoms. (medscape.com)
  • chronic rhinosinusitis, asthma, aspirin sensitivity and cystic fibrosis, which leads to the inflammation are may considered as the risk factors for the adoption of this disease. (healthncare.info)
  • He made further familial investigations afterwards, but never recognised the autosomal recessive inheritance or the presence of male infertility, which was added to the syndrome afterwards. (wikipedia.org)
  • Kartagener M, Horlacher A: Situs viscerum inversus und Polyposis nasi in einem Faile familiaerer Bronchiektasien. (medprep.info)
  • Immotile cilia syndrome (ICS) is an autosomal recessive disease with extensive genetic heterogeneity characterized by abnormal ciliary motion and impaired mucociliary clearance. (medscape.com)
  • Afzelius BA (1976) A human syndrome caused by immotile cilia. (wikipedia.org)
  • [ 3 ] Later studies showed that disorganized motion, rather than immotile cilia, resulted in the uncoordinated and ineffective ciliary beat, hence the term ciliary dyskinesia syndrome (CDS). (medscape.com)
  • Late in his life, Kartagener appears to have developed a polyneuropathic disorder which made him abandon his practice, and he died in Zurich in 1975. (wikipedia.org)
  • Dysfunction of the axonemal structure has been linked to the emerging class of disorders collectively known as ciliopathies, which includes PCD/Kartagener syndrome, Bardet-Biedl syndrome, hydrocephalus, polycystic kidney disease, polycystic liver disease, nephrolithiasis, Meckel-Gruber syndrome, and Joubert syndrome. (medscape.com)
  • Kartagener appointments, controlling the activity data and adverse effects of the drugs, with liver tests, hemogram, and transaminases. (bvsalud.org)
  • Chronic bronchitis, recurrent pneumonia, and bronchiectasis are common conditions in patients with primary ciliary dyskinesia and are often caused by pseudomonal infection. (medscape.com)
  • Kartagener main concern was bronchiectasis, which was controversially attributed to either congenital or acquired causes. (wikipedia.org)
  • M. Kartagener und K. Mully: Familial incidence of bronchiectasis. (wikipedia.org)
  • The inspiratory squeaks and crackles found in bronchiectasis are uncommon in chronic sinusitis. (kieran101.com)
  • Patients commonly present with chronic upper and lower respiratory tract infections resulting from an ineffective mucociliary mechanism. (medscape.com)
  • When taking a history, pertinent findings include chronic wet cough with unexplained respiratory distress. (medscape.com)
  • Conditions caused by abnormal CILIA movement in the body, usually causing KARTAGENER SYNDROME, chronic respiratory disorders, chronic SINUSITIS, and chronic OTITIS. (bvsalud.org)
  • He made further familial investigations afterwards, but never recognised the autosomal recessive inheritance or the presence of male infertility, which was added to the syndrome afterwards. (wikipedia.org)
  • Also, Kartagener syndrome is defined as genetic disorder along with autosomal recessive inheritance. (averroes-emj.com)
  • basal cell nevus syndrome an autosomal dominant syndrome characterized by the development in early life of numerous basal cell carcinomas, in association with abnormalities of the skin, bone, nervous system, eyes, and reproductive tract. (topgrowupclinic.eu)
  • These patients, therefore, should be closely followed and a specific treatment approach may be required, especially in the treatment of persistent middle ear effusion, as repeated grommet placement can predispose patients to chronic otitis and worsen the long-term prognosis. (medscape.com)
  • Afecciones causadas por un movimiento anormal de los CILIOS en el organismo, causando por lo general el SÍNDROME DE KARTAGENER, trastornos respiratorios crónicos, SINUSITIS crónica y OTITIS crónica. (bvsalud.org)
  • Cystic fibrosis (CF) is a chronic, multisystem disorder characterized by recurrent endobronchial infections, progressive obstructive pulmonary disease, and pancreatic insufficiency with intestinal malabsorption. (medscape.com)
  • Chronic sinusitis seems to be closely associated with endobronchial bacterial infections and may impact pulmonary reactivity and chronicity of disease within the sinobronchial tract. (medscape.com)
  • M. Kartagener: Hiatal hernia hemorrhage--a complication of anaesthesia. (wikipedia.org)
  • The recurrent chronic pansinusitis typically produces sinus pressure headaches in the maxillary and periorbital region. (medscape.com)
  • Sinus CT shows opacification of the involved facial sinus in chronic sinusitis. (kieran101.com)
  • [ 6 ] Decreasing exercise tolerance also often correlates with acute sinus exacerbations or worsening chronic disease. (medscape.com)
  • bradycardia-tachycardia syndrome , brady-tachy syndrome a clinical manifestation of the sick sinus syndrome characterized by alternating periods of bradycardia and tachycardia. (topgrowupclinic.eu)
  • Bernard-Soulier syndrome a hereditary coagulation disorder marked by mild thrombocytopenia, giant and morphologically abnormal platelets, hemorrhagic tendency, prolonged bleeding time, and purpura. (topgrowupclinic.eu)
  • bowel bypass syndrome a syndrome of dermatosis and arthritis occurring some time after jejunoileal bypass, probably caused by immune reponse to bacterial overgrowth in the bypassed bowel. (topgrowupclinic.eu)
  • Börjeson's syndrome , Börjeson-Forssman-Lehmann syndrome a hereditary syndrome, transmitted as an X-linked recessive trait, characterized by severe mental retardation, epilepsy, hypogonadism, hypometabolism, marked obesity, swelling of the subcutaneous tissues of the face, and large ears. (topgrowupclinic.eu)
  • acquired immune deficiency syndrome , acquired immunodeficiency syndrome an epidemic, transmissible retroviral disease caused by infection with the human immunodeficiency virus, manifested in severe cases as profound depression of cell-mediated immunity, and affecting certain recognized risk groups. (topgrowupclinic.eu)
  • Patients may exhibit chronic, thick, mucoid rhinorrhea from early in childhood. (medscape.com)
  • Aarskog syndrome , Aarskog-Scott syndrome a hereditary X-linked condition characterized by ocular hypertelorism,anteverted nostrils, broad upper lip, peculiar scrotal "shawl" above the penis, and small hands. (topgrowupclinic.eu)
  • [ 14 ] Coupled with improper drainage of the sinonasal system, this leads to congestion, rhinorrhea, and chronic middle ear effusions with possible purulent otorrhea. (medscape.com)
  • Barrett's syndrome peptic ulcer of the lower esophagus, often with stricture, due to the presence of columnar-lined epithelium, which may contain functional mucous cells, parietal cells, or chief cells, in the esophagus instead of normal squamous cell epithelium. (topgrowupclinic.eu)
  • Budd-Chiari syndrome symptomatic obstruction or occlusion of the hepatic veins, causing hepatomegaly, abdominal pain and tenderness, intractable ascites, mild jaundice, and eventually portal hypertension and liver failure. (topgrowupclinic.eu)