• This article will introduce an important research development to provide an evidence-based approach to current treatment methods and practices for young patients. (lww.com)
  • Methods Of 105 consecutive eyes (105 treatment-naïve patients) with ME following BRVO, 89 eyes were followed for 2 years after the first injection. (bmj.com)
  • Response adaptive randomization methods that skew allocation towards the superior treatment arm in clinical trials have been shown to maintain power and maximize total expected response. (amstat.org)
  • These methods assume patients that withdraw from the study have outcomes similar to those that complete the study. (amstat.org)
  • Methods: Pooled PANSS data from 15 clinical trials (n=1338), which included both acute and chronic schizophrenic patients with different study periods (6, 8, 12 and 54 weeks), were used to describe the time course of PANSS using NONMEM VI. (rug.nl)
  • Methods-- We implemented a pragmatic cluster randomized controlled trial to test the effectiveness of an automated interactive voice response tool designed to provide physicians with real-time patient-reported data about responses to newly prescribed diabetic peripheral neuropathy medicines. (cdc.gov)
  • Despite these efforts to disassociate the use of substances and pregnancy, there was still a lack of response using the traditional methods of recruitment (newspaper advertisements and craigslist posts). (cdc.gov)
  • The American College of Rheumatology (ACR) efficacy response criteria were used. (nih.gov)
  • The main factor influencing therapeutic efficacy is the prior response to DMARD treatment. (nih.gov)
  • The current study aimed to examine whether treatment self-efficacy (self-efficacy regarding the mastery of obstacles during treatment) in guided Internet-delivered therapy for anxiety disorders in adults could be a predictor of lower dropout rates and greater symptom reduction. (frontiersin.org)
  • Treatment self-efficacy was measured at pre-treatment. (frontiersin.org)
  • The results showed that high treatment self-efficacy was a predictor of both lower dropout rates and greater symptom reduction. (frontiersin.org)
  • Significant interaction effects between time and treatment self-efficacy were found for several of the nine modules that constitutes the treatment program, suggesting that treatment self-efficacy could be a moderator of symptom reduction. (frontiersin.org)
  • The results suggest that measuring treatment self-efficacy may be a valuable tool to identify patients at risk of dropping out, and that treatment self-efficacy could be a predictor and moderator of symptom reduction in guided Internet-delivered therapy. (frontiersin.org)
  • This meta-analysis aimed to determine the efficacy, acceptability and tolerability of quetiapine treatment for major depressive disorder (MDD). (biomedcentral.com)
  • The efficacy outcomes were the mean change scores of depression rating scales, the overall response rate, and the overall remission rates. (biomedcentral.com)
  • The reduction of harm through an ineffective treatment, the possibility of individualized dosing, the reduction of sample size, and the possible evaluation of the influence of the placebo effect on efficacy outcomes justify this design for a single-centered placebo-controlled investigator-initiated trial of nabilone. (springer.com)
  • This study should be the basis for further evaluations of long-term efficacy and safety of the use of cannabinoids in PD patients. (springer.com)
  • The demonstration of efficacy of clozapine in treatment resistant schizophrenia has led to studies looking into the efficacy of various treatments in this patient group. (priory.com)
  • This article reviews some studies looking into treatment efficacy in treatment resistant schizophrenia. (priory.com)
  • For the purpose of review, a medline search was conducted looking for articles about efficacy of treatments in treatment resistant schizophrenia since 1990. (priory.com)
  • Some authors have studied the relationship between the duration and efficacy of clozapine treatment. (priory.com)
  • The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the management of patients with chronic obstructive pulmonary disease (COPD) is much debated. (ersjournals.com)
  • Many studies have explored the efficacy and safety of ICS in patients with COPD. (ersjournals.com)
  • Likewise, despite not specifically focusing on patients at increased ECOPD risk, TORCH and SUMMIT were large enough to demonstrate ICS efficacy on ECOPD [ 15 , 16 ]. (ersjournals.com)
  • Because epoetin alfa has demonstrated efficacy in correcting cancer-related anaemia, the impact of this treatment on quality of life was evaluated in a multinational, randomised, double-blind, placebo-controlled trial in 375 anaemic cancer patients receiving non-platinum-based chemotherapy. (nature.com)
  • For anorexia nervosa, recent reports described the efficacy of different treatment settings, lengths of hospital stay and high vs. low-calorie refeeding programmes. (lww.com)
  • In recent years, 2 enhanced IIVs, MF59-adjuvanted standard-dose IIV and a high-dose IIV that contains 4 times the hemagglutinin antigen of each virus compared with the standard-dose IIV, have been developed to improve the immune responses to and efficacy of standard-dose IIVs ( 15 , 16 ). (cdc.gov)
  • Their hope is that targeting this distinct pathway using safety signals "may provide an effective alternative or means to enhance treatment for individuals for whom the efficacy of exposure-based CBT is otherwise limited. (bbrfoundation.org)
  • This study aims to systematically review safety and efficacy of SGA LAIs in the maintenance treatment of bipolar disorder. (bmj.com)
  • Objectives: Unpredictable variation in placebo response within and among clinical trials can substantially affect conclusions about the efficacy of new antipsychotic medications. (rug.nl)
  • At 5 years there was no longer any significant difference for clinical and radiographic outcomes between treatment strategies applied during the first 2 years. (bmj.com)
  • Patients with advanced melanoma treated with nivolumab had higher and more durable responses compared with investigator's choice of chemotherapy, but these increases did not result in improved survival outcomes. (cancernetwork.com)
  • secondary outcomes included evaluation of changes in Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire, tear film break-up time (TBUT), corneal and conjunctival staining, tear osmolarity, matrix metalloproteinase-9 (MMP-9), artificial tear use and safety assessments. (springer.com)
  • Eligible studies were randomized, placebo-controlled trials of quetiapine monotherapy carried out in adults with MDD and presenting endpoint outcomes relevant to: i) depression severity, ii) response rate, iii) overall discontinuation rate, or iv) discontinuation rate due to adverse events. (biomedcentral.com)
  • Therefore, unlike most motor features of PD, treatment options for NMS are limited and outcomes are often unsatisfactory (Kalia and Lang 2015 ). (springer.com)
  • Michael Lambert, a professor at Brigham Young University, summarized the results of 12 clinical trials that measured and monitored patient progress and feedback throughout the course of therapy and observed the effect of feedback on treatment outcomes. (madinamerica.com)
  • suggest that they estimate about 85% of their patients improve or recover, an estimate that far exceeds estimates based on measured outcomes in clinical trials and routine care. (madinamerica.com)
  • The specific aims of the study are to (1) demonstrate that AI-CBT has pain-related outcomes equivalent to standard telephone CBT, (2) document that AI-CBT achieves these outcomes with more efficient use of clinician resources, and (3) demonstrate the intervention's impact on proximal outcomes associated with treatment response, including program engagement, pain management skill acquisition, and patients' likelihood of dropout. (researchprotocols.org)
  • Outcomes will be measured at 3 and 6 months post recruitment and will include pain-related interference, treatment satisfaction, and treatment dropout. (researchprotocols.org)
  • identified program characteristics (eg, leadership support, well-defined staff roles, use of support and maintenance sessions) associated with successful program implementation (9,11,12) and better patient weight-loss outcomes (13). (cdc.gov)
  • 66 patients with the chronic fatigue syndrome who had neither a psychiatric disorder nor appreciable sleep disturbance. (bmj.com)
  • These findings support the use of appropriately prescribed graded aerobic exercise in the management of patients with the chronic fatigue syndrome. (bmj.com)
  • Patients with the chronic fatigue syndrome perceive greater fatigue than healthy controls taking the same exercise. (bmj.com)
  • 10 Fitness training improved both aerobic capacity and myalgia more than flexibility exercises in patients with the "fibrositis/fibromyalgia syndrome," 13 a condition which overlaps with the chronic fatigue syndrome. (bmj.com)
  • Patients met the Oxford criteria for the chronic fatigue syndrome. (bmj.com)
  • without treatment PTSD becomes chronic [ 3 ]. (nature.com)
  • Fatigue is a common side effect of tyrosine kinase inhibitor (TKI) therapy in chronic myeloid leukemia (CML) patients. (haematologica.org)
  • Survival of patients with chronic myeloid leukemia (CML) has improved significantly since the introduction of tyrosine kinase inhibitors (TKI) in 2001. (haematologica.org)
  • Preliminary covariate analysis indicated that females, subjects in long-term studies and chronic patients had lower probability of dropping out from trials compared to males, subjects of short-term studies and acute schizophrenic patients. (rug.nl)
  • Cognitive behavioral therapy (CBT) is one of the most effective treatments for chronic low back pain. (researchprotocols.org)
  • In total, 320 patients with chronic low back pain will be recruited from 2 VA healthcare systems and randomized to a standard 10 sessions of telephone CBT versus AI-CBT. (researchprotocols.org)
  • Dan Hussar was feeling fine after treatment for acute myeloid leukemia (AML). (mskcc.org)
  • Dan Hussar completed treatment for acute myeloid leukemia (AML) at his local medical center in April 2015. (mskcc.org)
  • Modeling and simulation of the time course of asenapine exposure response and dropout patterns in acute schizophrenia. (rug.nl)
  • Additional reasons for the difficulty in diagnosis include: medical illnesses and medication side effects that present similarly to depression, difficulty communicating with providers, lack of time in an appointment, and beliefs about mental illness and treatment from the patient, friends, family members, and society. (wikipedia.org)
  • However, medication dosages and treatment duration that define adequate drug trials have undergone revisions. (priory.com)
  • Here, we review the evidence available for ("friend") and against ("foe") ICS use in COPD and propose that ICS, added to one or two long-acting bronchodilators (never as stand-alone medication), can benefit some (but not all) COPD patients. (ersjournals.com)
  • The SAVER trial provides an opportunity to investigate the effects of a repurposed, inexpensive and well-tolerated medication as a potential chemopreventive strategy for patients with high-risk OED. (biomedcentral.com)
  • Greater connectivity in those regions, as demonstrated on fMRI, was significantly associated with remission with CBT and treatment failure with medication, whereas lower connectivity in the regions was predictive of remission with medication and treatment failure with CBT. (medscape.com)
  • Specifically, whereas the receipt of a patient's preferred modality (CBT or antidepressant medication) did not predict remission at 12 weeks ( P = .31), those patients who did not receive their preferred treatment modality were significantly more likely to drop out of the trial ( P = .01), usually within the first few weeks of treatment, said Dunlop. (medscape.com)
  • Treatment adherence was high (97%), and there were no dropouts because of the study medication. (medscape.com)
  • At the conclusion of the session, the participant will be able to describe Diagnostic and Statistical Manual of Mental Disorders 5th edition , DSM-5 assessment criteria for opioid use disorder, discuss the evidence for opioid use disorder medication assisted treatment with types of medications and settings used in medication assisted therapy. (cdc.gov)
  • See Treatment and Medication for more detail. (medscape.com)
  • Telephone Study, a randomized trial designed to improve medication treatment, titration and quality of life among patients with symptomatic diabetic peripheral neuropathy. (cdc.gov)
  • Patients assigned to physicians in the intervention group receive three brief interactive calls every 2 months after a medication is prescribed to alleviate diabetic peripheral neuropathy symptoms. (cdc.gov)
  • These calls provide patients with the opportunity to report on symptoms, side effects, self-titration of medication dose and overall satisfaction with treatment. (cdc.gov)
  • The overall survival outcome may have been impacted by the increased dropout rate before treatment and increased systemic therapy received after assigned therapy in the investigator's choice of chemotherapy group, as well as an increased proportion of patients with poor prognostic factors in the nivolumab group," wrote James Larkin, PhD, FRCP, of Royal Marsden NHS Foundation Trust, United Kingdom, and colleagues. (cancernetwork.com)
  • The trial randomly assigned patients 2:1 to nivolumab 3 mg/kg every 2 weeks or investigator's choice of chemotherapy (dacarbazine or carboplatin/paclitaxel). (cancernetwork.com)
  • Although there were no survival differences between nivolumab and investigator choice chemotherapy treatments, nivolumab treatment after progression on ipilimumab with or without a BRAF inhibitor does provide a higher rate of response and more durable responses," the researchers wrote. (cancernetwork.com)
  • Some situations may still exist that necessitate the use of ipilimumab as first-line therapy and nivolumab provides a safer option with a better maintained quality of life for patients who have experienced failure with prior systemic therapies compared with cytotoxic chemotherapy. (cancernetwork.com)
  • The hypothesis was that Chinese herbal medicine added to chemotherapy for the treatment of HCC would improve survival and tumor re- sponse, when compared to treatment with chemotherapy alone. (pinestreetfoundation.org)
  • They retained those that (1) treated only HCC pa- tients, (2) were described as randomized or reported that there was no statistical difference between treatment groups, (3) gave patients either Chinese herbal medicine therapy combined with chemotherapy in the treatment group or chemotherapy alone in the control group, and (4) provided data on the number of enrolled subjects and re- sponders and nonresponders for tumor response and sur- vival. (pinestreetfoundation.org)
  • 000). Conclusions: These findings provide promising evidence that combining Chinese herbal medicine with chemotherapy may benefit patients with HCC. (pinestreetfoundation.org)
  • Additionally, patients who received multimodal therapy-radiotherapy, chemotherapy, and/or surgery-have a higher risk of developing mental health disorders compared with those who receive only surgery, according to the report. (psychnews.org)
  • Obesity management guidelines specify initial goals for participation and weight reduction for the first 6 months of a weight-reduction intervention, but guidelines do not specify when to assess early response and make adjustments. (cdc.gov)
  • early response also predicted 1-year success, suggesting that the 2-week point may be an ideal time to assess initial response and make intervention adjustments. (cdc.gov)
  • Many cancer patients require therapeutic intervention to correct the underlying anaemia. (nature.com)
  • Objective To investigate associations between the expression of circulating adiposity-related miRNAs and the response to a weight loss intervention. (unav.edu)
  • Thus, miR-221-3p could be used for predicting the response to a multidisciplinary intervention for weight loss in young girls. (unav.edu)
  • This study will evaluate an intervention that increases patients' access to effective CBT pain management services while allowing health systems to maximize program expansion given constrained resources. (researchprotocols.org)
  • We plan to Author Manuscript compare changes in self-reported quality of life between the intervention group and patients in the control group who receive three non-interactive automated educational phone calls. (cdc.gov)
  • Treatments for late-life depression include medicine and psychotherapy, along with lifestyle changes such as exercise, bright light therapy, and family support. (wikipedia.org)
  • Lambert suggests that this discrepancy between clinicians' ability to discern client progress and their realistic state of progress may be underlying issues in psychotherapy treatment including patient deterioration, treatment failure, and client dropout. (madinamerica.com)
  • Although CBT was equally efficacious to certain psychological treatments, the fact that CBT outperformed all active psychological comparisons and interpersonal psychotherapy specifically, offers some support for the specificity of psychological treatments for eating disorders. (researchgate.net)
  • Treatment usually consists of medications, psychotherapy, or both and sometimes electroconvulsive therapy (ECT) or rapid transcranial magnetic stimulation (rTMS). (msdmanuals.com)
  • In this sense, in view of its effective character and the positive results obtained with online treatment (Pieta & Gomes, 2014), it has been observed that online psychotherapy, which until November 2018 was only allowed in the form of research, ceased to be object of study and gained legitimacy from the CFP (2018). (bvsalud.org)
  • The present study investigates 5-year data of a 2-year methotrexate (MTX) based tight control treatment (TC) strategy compared to conventional MTX-based treatment (CT) strategy, and the (added) predictive value of an early response (at 6 months) to treatment for 5-year outcome with respect to disease activity and radiographic progression. (bmj.com)
  • Developing a robust placebo model accounting for factors like dropouts, disease progression and trial design is crucial in order to facilitate better quantification of drug effect. (rug.nl)
  • This co-occurrence might lead to an impairment of cognitive functions, worse response to antidepressant medications, and an increased risk of suicide in comparison to patients with PTSD alone. (frontiersin.org)
  • Meta-analysis data indicate that in as many as 52% patients with a posttraumatic stress disorder (PTSD), major depressive disorder (MDD) co-occurs, which might lead to an impairment of cognitive functions, worse response to antidepressant medications, and an increased risk of suicide in comparison to patients with PTSD alone ( 1 ). (frontiersin.org)
  • Evidence-based psychological treatments, such as cognitive behavior therapy (CBT), have been found to be effective in treating several anxiety and mood disorders. (jmir.org)
  • Inference-based cognitive-behavioral therapy (I-CBT) is a specialized psychological treatment for obsessive-compulsive disorder (OCD) without deliberate and prolonged exposure and response prevention (ERP) that focuses on strengthening reality-based reasoning and correcting the dysfunctional reasoning giving rise to erroneous obsessional doubts and ideas. (karger.com)
  • Fujii et al (1997) reported that patients with treatment resistant schizophrenia show significant global cognitive improvement, as measured by Wechsler Adult Intelligence Scale-Revised (WAIS-R) Full Scale, after a minimum of one year of treatment with clozapine. (priory.com)
  • The best available treatment for such people is cognitive behavioral therapy (CBT), specifically aimed at exposing an individual to a stimulus that triggers their fear response and teaching them to extinguish that fear ("fear extinction") when an actual threat is not present. (bbrfoundation.org)
  • In PREDICT, patients with MDD were randomly assigned to receive either 12 weeks of cognitive-behavioral therapy (CBT) or 12 weeks of therapy with antidepressant therapy with the selective serotonin reuptake inhibitor (SSRI) escitalopram ( Lexapro , Forest Labs) or the serotonin and norepinephrine reuptake inhibitor (SNRI) duloxetine ( Cymbalta , Lilly). (medscape.com)
  • We searched systematically for randomised controlled clinical trials on treatment of RA with anti-TNFalpha drugs, followed by a systematic review with metaanalysis. (nih.gov)
  • It can arise due to all sorts of reasons, such as faulty machinery in lab experiments, patients dropping out of clinical trials, or non-response to sensitive items in surveys. (lshtm.ac.uk)
  • Previous literature has found that approximately 20-40% of patients fail to respond to treatment in clinical trials, and prospects are even worse in child or adolescent samples. (madinamerica.com)
  • Nevertheless, issues regarding adherence are common, such as poor patient compliance on homework assignments and therapists' drifting from strictly evidence-based CBT. (jmir.org)
  • This is further supported by the finding that adverse events lead to lower TKI treatment adherence 3 and therefore to poorer disease control. (haematologica.org)
  • Introduction Bipolar disorder requires long-term treatment but non-adherence is a common problem. (bmj.com)
  • Conclusions The difference in disease activity between treatment strategies disappeared over the years. (bmj.com)
  • There were some limitations regarding methodological flaws and the AMSTAR-2 tool use CONCLUSIONS: These findings reveal a frail methodological quality of systematic reviews about vesiculobullous diseases treatment that may impact the results. (bvsalud.org)
  • Conclusions-- Innovative strategies are needed to guide improvements in healthcare delivery for patients with symptomatic diabetic peripheral neuropathy. (cdc.gov)
  • Concurrent medical problems and lower functional expectations of elderly patients also often obscure the degree of impairment caused by late-life depression. (wikipedia.org)
  • Elderly persons sometimes dismiss less severe depression as an acceptable response to life stress or a normal part of aging. (wikipedia.org)
  • Primary care is most often where diagnosis and treatment of late-life depression occurs. (wikipedia.org)
  • Diagnosis of depression in late life is made using the same criteria for Major Depressive Disorder found in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) To meet criteria for a major depressive episode, a patient must have five of the nine symptoms listed below nearly every day for at least two weeks and must have at least either a depressed mood or anhedonia. (wikipedia.org)
  • The study indicates the possibility of using heated yoga as a viable treatment option for depression, as 44% of the participants who took up the sessions indicated signs of remission. (medicaldaily.com)
  • The study involved 15 patients with mild to moderate anxiety or depression (or both). (jmir.org)
  • Recent studies show that there is new hope in the treatment of depression and anxiety that is more effective than antidepressants. (netgalley.com)
  • This review is focused on as SGA LAIs since first generation antipsychotics are not considered preferred choice in maintenance treatment of bipolar disorder due to risk of induction of depression. (bmj.com)
  • Further analyses from the Prediction of Remission to Individual and Combined Treatments (PREDICT) randomized controlled trial, which included 344 treatment-naive patients with MDD, as well as findings from the 1000 patient‒strong international Study to Predict Optimized Treatment in Depression (iSPOT-D), were presented here at the Anxiety and Depression Association of America (ADAA) 2018 Conference. (medscape.com)
  • Newer findings were presented by Craighead with respect to 112 participants whose depression failed to go into remission during the initial 12 weeks of treatment. (medscape.com)
  • Randomised controlled trial with control treatment crossover after the first follow up examination. (bmj.com)
  • Anorexia nervosa and atypical anorexia nervosa are by far the most prevalent eating disorders among patients admitted to child and adolescent psychiatric (CAP) treatment or to paediatric units with a CAP liaison service, whereas patients with bulimia nervosa and avoidant/restrictive food intake disorder (ARFID) are seen comparatively less often. (lww.com)
  • The flaws of this method are particularly prevalent if dropout rates differ between the treatment arms. (amstat.org)
  • Indeed, confrontation and humiliation actually increase relapse and dropout. (time.com)
  • Although there is some evidence of the effectiveness of new child and adolescent psychiatric treatment approaches to eating disorders, the relapse rate remains very high, and there is an urgent need for ongoing intensive research. (lww.com)
  • Research shows, for example, that enforcing strict rules like allowing shaving only on particular days only increases dropout. (time.com)
  • Another narrative indicates that crime increases by people leaving treatment and remaining in the area. (thecounselingcenter.org)
  • The aim of the present study was to explore whether single nucleotide polymorphisms (SNPs) within HSP90AA1 gene affect the response of systemic lupus erythematosus (SLE) patients to GCs treatment. (springeropen.com)
  • No moderate or severe systemic reactions were seen in the treatment group. (medscape.com)
  • Approximately 30% of schizophrenic patients (10-45%) meet these criteria. (priory.com)
  • Rodriguez et al (1998) compared clozapine responders, partial responders and non-responders from a group of resistant schizophrenic patients. (priory.com)
  • Meltzer and Okayli (1995) have reported decrease in suicidality of treatment resistant schizophrenic patients with clozapine treatment of 6 months to 7 years duration. (priory.com)
  • Jalenques et al (1992), in an open prospective trial of clozapine in treatment resistant schizophrenic patients reported significant improvement in positive symptoms by 1 month and negative symptoms by 3 months with improvement in social functions and reduction in use of concomitant medications. (priory.com)
  • This treatment provides rates of sustained virological response (SVR, undetectable serum levels of HCV RNA at least 6 months after completion of therapy) of 40-50% among patients with HCV genotype 1 (G1) who have not received previous treatment (treatment-naïve patients) [ 1 - 3 ]. (hindawi.com)
  • Telaprevir, a first generation orally bioavailable inhibitor of the nonstructural 3/4A HCV protease, shows significantly higher rates of SVR than standard care of PEG-IFN α and ribavirin in patients with HCV G1 disease when given for 12 weeks in combination with regimens of PEG-IFN α plus ribavirin lasting 12, 24, or 48 weeks [ 4 - 6 ]. (hindawi.com)
  • Although the SVR rates in patients receiving telaprevir with PEG-IFN α and ribavirin (triple therapy) were higher than those in PEG-IFN α plus ribavirin (combination therapy) patients, drop-out rates due to increased side effects were also higher in the triple therapy patients [ 4 - 6 ]. (hindawi.com)
  • Hence, ways to optimize the delivery of CBT, improve response rates, and increase the treatment's availability represent important goals for the field. (jmir.org)
  • The overall response and remission rates were significantly greater in the quetiapine-treated group with RRs (95%CIs) of 1.44 (1.26, 1.64) and 1.37 (1.12, 1.68), respectively. (biomedcentral.com)
  • Later RCTs of ICS/long-acting β 2 -agonist (LABA) combinations generally recruited patients with ≥1 ECOPD in the previous year, and showed that ICS/LABA combinations reduce ECOPD rates by approximately 25-35% compared with LABA monotherapy ( figure 1 ) [ 3 - 14 ]. (ersjournals.com)
  • More recently, two RCTs (IMPACT and TRIBUTE) compared triple therapy versus LABA/long-acting muscarinic antagonist (LAMA) combinations in patients at high ECOPD risk, and also showed a 15-25% reduction in ECOPD rates ( figure 1 ) [ 17 , 18 ]. (ersjournals.com)
  • Recent analysis of recurrence rates in 94 patients who experienced remission after receiving 12 weeks of either CBT or pharmacotherapy showed that 15.5% experienced a recurrence during the maintenance period, study coauthor W. Edward Craighead, PhD, Department of Psychiatry and Behavioral Sciences at Emory University, Atlanta, Georgia, reported. (medscape.com)
  • WASHINGTON - Predictors of response to mainstream therapies for major depressive disorder (MDD) range from baseline comorbid anxiety, brain connectivity patterns on neuroimaging, genomic patterns, and novel findings of inflammatory system abnormalities, new research suggests. (medscape.com)
  • 14 A similar training programme improved symptoms and physiological findings in an open study of patients with the "effort syndrome. (bmj.com)
  • Triple therapy is associated with increased risks of anemia, skin lesions, digestive symptoms, hyperuricemia, renal dysfunction, and other side effects compared to the combination therapy, especially among women and older patients [ 4 , 7 , 8 ]. (hindawi.com)
  • Patients in OST have a high degree of physical symptoms and a high degree of unmet healthcare needs. (hindawi.com)
  • Patients in OST carry a heavy burden of physical symptoms and unmet healthcare needs, potentially due to societal barriers. (hindawi.com)
  • Using an image-guided minimally invasive procedure that takes less than 10 minutes, patients could alleviate symptoms of parosmia, a condition characterized by a distorted sense of smell. (medicaldaily.com)
  • Artificial tears and topical corticosteroids used as first-line treatments usually improve the symptoms of dry eyes but are associated with adverse effects with long-term use. (springer.com)
  • Although open-label observations report a positive effect of cannabinoids on non-motor symptoms (NMS) in Parkinson's disease (PD) patients, these effects remain to be investigated in a controlled trial for a broader use in NMS in PD patients. (springer.com)
  • Though various authors have used varied definitions of treatment resistant schizophrenia, the most common definition of treatment resistant schizophrenia denotes patients who despite at least two adequate trials of classical neuroleptic drugs have persistent moderate to severe, positive, or disorganization, or negative symptoms together with poor social and work function over a prolonged period of time (Meltzer 1997). (priory.com)
  • The primary end point was the proportion of week 12 responders (patients with moderate or substantial improvement in IBS symptoms) on the 7-point Likert Global Improvement Scale (GIS). (researchgate.net)
  • study reveal that hydrocortisone augmentation during prolonged exposure therapy may result in a greater retention in the treatment group, thereby improving PTSD symptom response ( 7 ). (frontiersin.org)
  • Difficulty controlling fear when it is not an appropriate response to current conditions is a symptom often seen in people with anxiety disorders as well as those with post-traumatic stress disorder (PTSD) . (bbrfoundation.org)
  • Background-- Challenges to effective pharmacologic management of symptomatic diabetic peripheral neuropathy include the limited effectiveness of available medicines, frequent side effects, and the need for ongoing symptom assessment and treatment titration for maximal effectiveness. (cdc.gov)
  • This trial aims to assess whether real-time collection and clinical feedback of patient treatment experiences can reduce patient symptom burden. (cdc.gov)
  • Analysis by intention to treat gave similar results (17/33 v 9/33 patients better). (bmj.com)
  • Results 5 years of data were available for 205 of 299 patients, with no indication for selective drop-out. (bmj.com)
  • Anti-TNFalpha drugs are effective in RA patients, with apparently similar results irrespective of the drug administered. (nih.gov)
  • The results suggest that modern information technology can effectively blend with face-to-face treatments and be used to facilitate communication and structure in therapy, thus reducing therapist drift. (jmir.org)
  • Results: Twenty-six studies representing 2079 patients met the inclusion criteria. (pinestreetfoundation.org)
  • Results depend on the characteristics of the population studied, the comparator treatment and the selected clinical outcome(s). (ersjournals.com)
  • For the newly defined ARFID, only very preliminary results on possible treatment approaches implying a multidisciplinary treatment programme were obtained. (lww.com)
  • 2 CML patients require (potentially) lifelong treatment, which results in a persistent trigger for fatigue. (haematologica.org)
  • Results: The Weibull model and an indirect response model (IRM) with exponential infusion type of kinetic-PD function described the PANSS data well compared to other placebo models. (rug.nl)
  • Results of simultaneous modeling of dropout model with placebo model indicated that the probability of patients dropping out from a clinical trial is associated with both the last observed PANSS measurement and unobserved PANSS score as predicted by the placebo model. (rug.nl)
  • Our results further support the importance of addressing psychosocial needs in routine treatment discussions. (psychnews.org)
  • Patient enrollment will begin in the fall of 2016 and results of the trial will be available in the winter of 2019. (researchprotocols.org)
  • Results showed that after switching treatment, 48.2% of the patients experienced remission. (medscape.com)
  • This reduction results from the decrease in the number of new cases of the disease, the shorter treatment time and the improvement of information systems. (bvsalud.org)
  • The majority of patients in Japan who are infected with HCV genotype 1b (G1b) are older than the patients in the United States and/or Europe and the frequency of patients who discontinued due to adverse events was reported to be as high as 11.1-16.7% [ 7 - 9 ]. (hindawi.com)
  • The high dropout rate due to adverse events suggests that some MDD patients may not be able to tolerate quetiapine XR. (biomedcentral.com)
  • The treatment resistance of patients with schizophrenia is a frequent and important clinical problem. (priory.com)
  • The proportion of patients with treatment resistant schizophrenia has been consistent over time since the introduction of conventional antipsychotics (Conley and Buchanan, 1997). (priory.com)
  • The key words used for the search were: treatment, schizophrenia and resistant. (priory.com)
  • A narrow definition of treatment resistant schizophrenia was introduced by Kane et al (1988). (priory.com)
  • Since the landmark study of clozapine by Kane et al (1988), various authors have studied different aspects of clozapine in treatment resistant schizophrenia. (priory.com)
  • The objectives of this study were i) to develop a model for placebo response in schizophrenia as measured with the Positive and Negative Syndrome Scale (PANSS) under varying clinical trial conditions, accounting for dropout and other relevant predictors of the placebo response, ii) to compare different Time to Event (TTE) modeling approaches used to describe the dropout patterns following placebo treatment in schizophrenia. (rug.nl)
  • The study suggests the possibility of using trans-vaccenic acid found in red meat and dairy products as a nutritional supplement to complement treatments for cancer. (medicaldaily.com)
  • However, a review of immunogenicity studies suggests that antibody responses to inactivated influenza vaccines (IIVs) in persons who are immunocompromised could be suboptimal compared with persons without immunosuppression ( 11 ). (cdc.gov)
  • The research suggests it may be possible to develop a new way of treating people who have difficulty controlling their fearful or anxious responses to perceived threats. (bbrfoundation.org)
  • The discrepancy between clinician estimates of success and measured success suggests the need for formally measuring and monitoring treatment response. (madinamerica.com)
  • Multiple regression analysis showed that early response to treatment is an independent predictor of 5-year outcome, irrespective of treatment strategy. (bmj.com)
  • Good-response to treatment independently predicts significantly better 5-year clinical and radiographic outcome. (bmj.com)
  • 1 , - , 4 Next to known predictors of long-term outcome of RA, which are assessed at baseline, 5 , - , 8 early response to treatment also could be predictive. (bmj.com)
  • 9 Disease activity during the first 3 months of treatment has been related to clinical and radiographic outcome after the first year of treatment, 6 10 11 and an early treatment response can predict the long-term work disability outcome. (bmj.com)
  • However, neither a substitution in core aa 70 nor the number of substitutions in the ISDR affected treatment outcome. (hindawi.com)
  • The outcome of the triple therapy in patients who had previously received the combination therapy was largely dependent on the response to the previous therapy [ 10 , 11 ]. (hindawi.com)
  • Although the significance of substitution in the core aa 70 on the outcome of the triple therapy has been reported [ 8 , 9 ], a considerable number of the patients with a history of the combination therapy were included in these reports. (hindawi.com)
  • However, not all patients experience improvement, and although predictors of treatment outcome have been identified, few are consistent over time and across studies. (frontiersin.org)
  • It complements a similar review of the alliance-outcome link in therapy for individual patients. (findings.org.uk)
  • A total of 38 patients will have 80% power to detect a probability of 0.231 that an observation in the treatment group is less than an observation in the placebo group using a Wilcoxon rank-sum test with a 0.050 two-sided significance level assuming a true difference of 2.5 points between nabilone and placebo in the primary outcome measure and a standard deviation of the change of 2.4 points. (springer.com)
  • Clinicians appear to be overly optimistic about patient benefits compared to measured outcome. (madinamerica.com)
  • Unfortunately, the clinicians' view of their own patients' outcome is much more positive than the measured outcome using self-report scales. (madinamerica.com)
  • This multicenter study involved 150 Asian treatment-naïve patients infected with HCV G1b who received 12 weeks of telaprevir in combination with 24 weeks of peginterferon- α -2b and ribavirin. (hindawi.com)
  • In the present study, the SVR rate was examined in treatment-naïve patients with HCV G1b who were treated with a regimen consisting of 12 weeks of telaprevir, combined with PEG-IFN α and ribavirin, followed by 12 weeks of the PEG-IFN and ribavirin. (hindawi.com)
  • Not one study has ever found that disrespecting or humiliating people with addiction is effective treatment. (time.com)
  • The aim of this study is to assess OST patients' self-rated physical health and healthcare seeking behaviour. (hindawi.com)
  • Treatment with a new class of drugs, called senolytics, in donors improved the physical fitness of the recipients, a new study has shown. (medicaldaily.com)
  • Over 20% of patients taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, suffer from the rebound, compared to less than the 2% chance seen in other treatment groups, a Harvard Medical School study revealed. (medicaldaily.com)
  • We conducted a KAP study among 70 CL patients attending 4 clinics in Aleppo. (who.int)
  • In this study, we developed and tested a new treatment format in which ICBT and face-to-face therapy were blended. (jmir.org)
  • We used a simple formula - weight reduction of 1.0% or more at the end of 4 weeks (1 month) - to achieve our primary study objective: to determine if an early response would predict successful weight reduction (5% or more) at 6 months among participants in a weight-reduction program. (cdc.gov)
  • This study provides a step toward precision therapeutics for PTSD by demonstrating that comorbid MDD and genetic markers may help guide treatment selection. (nature.com)
  • The analyzed data comes from an open effectiveness study including 575 patients receiving guided Internet-delivered therapy for panic disorder or social anxiety disorder. (frontiersin.org)
  • Therefore, we decided to design a proof-of-concept study to assess the synthetic cannabinoid nabilone for the treatment of NMS. (springer.com)
  • Clinical effectiveness data are sparse, but a recent observational study demonstrated lower vaccine effectiveness against influenza illness (≈20%) in patients with cancer compared with the general population (≈42%) ( 12 , 13 ). (cdc.gov)
  • In 2009, the Standard Care versus Corticosteroid for Retinal Vein Occlusion (SCORE) study 2 found that 29% of eyes treated with laser photocoagulation gained 15 or more letters of VA measured using the Early Treatment Diabetic Retinopathy Study (ETDRS) 3 chart at the 1-year primary end point. (bmj.com)
  • In this study, 220 CML patients receiving TKI therapy and 110 gender- and age-matched controls completed an online questionnaire to assess fatigue severity and fatigue predictors (Part 1). (haematologica.org)
  • This study will clarify the position of second-generation antipsychotics (SGAs) long-acting injections (LAIs) in maintenance treatment of bipolar disorder. (bmj.com)
  • OBJECTIVE: This meta-epidemiological study aimed to map and critically appraise systematic reviews assessing treatments for vesiculobullous skin diseases. (bvsalud.org)
  • A qualitative sub-study will explore patient experience and perception of the trial. (biomedcentral.com)
  • The present study demonstrates that HSP90AA1 gene SNPs may affect the response of SLE patients to GCs treatment. (springeropen.com)
  • In this cohort study of 52,641 patients with a diagnosis of head and neck cancer, the proportion with mental health disorders at baseline was 20.6% compared with the national average of 17.9%, as estimated by the National Survey on Drug Use and Health. (psychnews.org)
  • This study was performed on 56 patients with leprosy: 28 under treatment and 28 treated for the disease. (bvsalud.org)
  • Thus, the present study aimed to evaluate the oral health status of patients with leprosy in relation to the presence of associated lesions, prevalence of caries and plaque accumulation. (bvsalud.org)
  • Several placebo models with determinants of placebo response were tested [1]. (rug.nl)
  • Influence of dropouts was investigated by exploring three TTE hazard models in conjunction with the best performing placebo models. (rug.nl)
  • All recent expert consensus guidelines recommend exposure therapy as a first-line treatment for PTSD. (nature.com)
  • Treatment of eating disorders in child and adolescent psychi. (lww.com)
  • Recent research on the multimodal treatment of eating disorders in child and adolescent psychiatry has yielded a significant increase in randomized controlled trials and systematic reviews. (lww.com)
  • Although data exist on the prevalence of some immunosuppressive conditions, the total burden of these conditions in the United States remains unknown, particularly when considering patients who are receiving emerging immunosuppressive therapies ( 6 - 8 ). (cdc.gov)
  • In response to the targeted therapies, the researchers found, the genomes of some melanoma cells experienced a process known as chromothripsis. (cancer.gov)
  • The challenge is to identify those patients with the highest benefit/risk ratio in clinical practice. (ersjournals.com)
  • We propose a response adaptive allocation ratio that adjusts for dropout, unrelated to unobserved treatment response, and factors in losses associated with discontinuation of treatment. (amstat.org)
  • When there is no dropout, our allocation ratio reduces to previously published response adaptive allocation ratios. (amstat.org)
  • Additionally, a decrease in the IgE/IgG4 ratio among active participants was indicative of an immunologic response to treatment with INT301, the data show. (medscape.com)
  • However, if the consequence of withdrawal is the discontinuation from treatment, this assumption may not be valid, leading to allocation that has less than optimal characteristics. (amstat.org)
  • Fatigue, functional capacity, and fitness were significantly better after exercise than after flexibility treatment. (bmj.com)
  • In considering misinformation, one narrative is that the local overdose crisis is significantly worsened by clients coming in from other areas, who drop out of treatment and stay here. (thecounselingcenter.org)
  • These findings provide evidence that increasing haemoglobin levels by epoetin alfa administration can significantly improve cancer patients' quality of life. (nature.com)
  • Treatment with Chinese herbal medicine has been explored, combining herbs that stimulate host immune response with those that have cytotoxic activity against HCC cells. (pinestreetfoundation.org)
  • Immunosuppressed patients have a high risk for influenza complications and an impaired immune response to vaccines. (cdc.gov)
  • Establishing a case definition for and quantifying the burden of immunosuppressive conditions might facilitate evaluation and use of influenza vaccines to enhance immune response in this high-risk target group. (cdc.gov)
  • But while it describes one woman's triumph, it also illustrates something the Institute of Medicine calls a " quality chasm " between effective addiction care, as supported by scientific research, and the treatments people actually receive. (time.com)
  • Although research shows that empathetic and supportive care is far more effective for overcoming addiction, many addicts don't even recognize that they deserve kind treatment, as Lute's story shows. (time.com)
  • Despite the lack of survival advantage, nivolumab remains an effective option for PD-1 inhibitor-naive patients who experienced failure with ipilimumab and a BRAF inhibitor if BRAF mutated. (cancernetwork.com)
  • therefore, researchers look for novel, effective treatments. (frontiersin.org)
  • Thus, there is a need for cost-effective and accessible treatments. (jmir.org)
  • PTSD remains a significant worldwide public health problem a generation after the World Trade Center attacks of September 11, 2001, which played a substantial role in underscoring the paucity of effective treatments for PTSD. (nature.com)
  • Guided Internet-delivered therapy has shown to be an effective treatment format for anxiety disorders. (frontiersin.org)
  • Based on the limited evidence obtained from three RCTs, quetiapine XR is effective for adult patients with MDD. (biomedcentral.com)
  • Unfortunately, there is unlikely to be a single effective strategy for treating the heterogeneous resistant tumors in these patients," Dr. Lo said. (cancer.gov)
  • 7-18 Prospective studies of ranibizumab (Lucentis, Genentech, Inc., South San Francisco, California, USA), a humanised, affinity-matured VEGF antibody fragment that neutralises all isoforms of VEGF-A and their biologically active degradation products in treatment-naïve eyes with ME following BRVO, found that ranibizumab was effective at 2 years after treatment of ME caused by BRVO. (bmj.com)
  • An effective response to a potential pandemic requires the infrastructure to rapidly detect, characterise, and potentially contain new and emerging influenza strains at both an individual and population level. (cdc.gov)
  • Unlike the cutaneous manifestations of the disease, which are well documented in the literature, descriptions of oral findings are scarcely detailed, making comparisons difficult, and old if the treatment of the disease was not effective 2-4,7,8 . (bvsalud.org)
  • In patients who do not respond to initial treatments, neurostimulation techniques such as electroconvulsive therapy (ECT) can be used. (wikipedia.org)
  • Cessation of the therapy due to adverse effects occurred in only 2 patients, who discontinued the trial at 10 weeks and at 2 weeks due to cerebral infarction and renal impairment, respectively. (hindawi.com)
  • In treatment-naïve patients, the genetic variation near the interleukin-28B (IL-28B) gene and amino acid (aa) substitution in the core 70 (core aa 70) of HCV may be the candidate predictors of the virological response to triple therapy. (hindawi.com)
  • According to Larkin and colleagues treatment options were needed for patients with advanced melanoma that had progressed with ipilimumab and BRAF inhibitor-based therapy. (cancernetwork.com)
  • Forty-one percent of patients in the investigator's choice arm received anti-PD-1 agents after therapy assignment compared with 11% of patients in the nivolumab arm. (cancernetwork.com)
  • In both, therapeutic goals and tasks need to be discussed and agreed early and as therapy evolves, and in both the therapist needs to 'click' emotionally with the patient(s). (findings.org.uk)
  • But they note that up to 50% of individuals with anxiety disorders do not respond sufficiently to such therapy, while up to 27% of patients drop out of treatment. (bbrfoundation.org)
  • Although a variety of predictors of fatigue, such as gender, age and socioeconomic status have been described in literature, 7-9 it is unknown whether these predictors, even when obtained in cancer populations, can be extrapolated to this unique group of CML patients on TKI therapy. (haematologica.org)
  • After the initial 12 weeks, patients who did not respond to therapy were switched to the opposing therapy for another 12 weeks. (medscape.com)
  • In other words, patients who failed to respond to antidepressant therapy would be switched to CBT, and vice versa. (medscape.com)
  • These patients were switched to the alternative therapy. (medscape.com)
  • In addition to the clinical predictors, findings from pretreatment resting-state functional MRI (fMRI) for 112 patients showed significant differences between those who did and those who did not achieve remission with CBT compared with antidepressant therapy, reported coauthor Boadie Dunlop, MD, of Emory University. (medscape.com)
  • Objective monitoring of activity patterns confirmed that fatigued CML patients performed less physical activity on both light (P=0.017) and moderate to vigorous intensity (P=0.009). (haematologica.org)
  • Despite increasing awareness in recent years, NMS in PD are still frequently missed or undeclared during routine consultations and well-performed large-scale randomized controlled trials (RCTs) for the treatment of the different NMS in PD are lacking (Schrag et al. (springer.com)
  • Several important randomized controlled trials (RCTs) and systematic reviews comparing different treatment settings, refeeding practices and psychotherapeutic interventions for adolescent and childhood anorexia nervosa have been recently published. (lww.com)
  • Missing Not At Random (MNAR), where dropout depends on predicted PANSS [2]. (rug.nl)
  • Thirteen trials (7087 patients) met the inclusion criteria. (nih.gov)
  • For both anorexia and bulimia nervosa, a number of randomized controlled trials comparing individual and family-oriented treatment approaches were published. (lww.com)
  • Patients receiving infliximab were more likely to drop out because of side effects (NNH 24) and to suffer severe side effects (NNH 31), infections (NNH 10) and infusion reactions (NNH 9). (nih.gov)
  • Patients receiving adalimumab were also more likely to drop out because of side effects (NNH 47) and to suffer injection site reactions (NNH 22). (nih.gov)
  • Patients in opioid substitution treatment (OST) are suspected to suffer from poor health due to prior, or ongoing, substance use [ 1 ]. (hindawi.com)
  • Approximately half of all patients with posttraumatic stress disorder (PTSD) also suffer from major depressive disorder (MDD). (frontiersin.org)
  • 1995 ). However, SLE patients often suffer long-term morbidity that can adversely affect their ability to work as well as quality of life (Pons-Estel et al. (springeropen.com)
  • We designed a support system accessible via the Internet (using a computer or an Apple iPad) for patients and therapists delivering CBT face-to-face. (jmir.org)
  • Eight therapists conducted the treatments. (jmir.org)
  • This is despite deliberate attempts to provide evidence-based treatment from demonstrably successful therapists after patients with the same "disorder" have been carefully screened. (madinamerica.com)
  • However, only half of Department of Veterans Affairs (VA) patients have access to trained CBT therapists, and program expansion is costly. (researchprotocols.org)
  • The effect of treatment with etanercept or adalimumab does not differ from that obtained with MTX. (nih.gov)
  • High mortality and morbidity associated with HNCs [head and neck cancers] may predispose these patients to MHDs [mental health disorders]," wrote Neerav Goyal, M.D., M.P.H., of Pennsylvania State University and colleagues. (psychnews.org)
  • In addition, morbidity is associated with the treatment. (psychnews.org)
  • All studies defined the response and remission as ≥ 50% reduction of the MADRS total score and the MADRS total score of ≤8 at endpoint, respectively. (biomedcentral.com)
  • The program follows evidence- based obesity treatment guidelines and has a comprehensive, multidisciplinary approach to weight management (10). (cdc.gov)
  • 16 In addition, by using the structured clinical interview for the DSM-III-R ( Diagnostic and Statistical Manual of Mental Disorders , third edition, revised) 17 we excluded patients who also had a current psychiatric disorder or symptomatic insomnia because of the separate effects of these conditions on fatigue. (bmj.com)
  • The Malmö Addiction Centre, geographically located within the Malmö University Hospital, includes an emergency addiction unit, an in-patient detox ward for opioid dependence and a psychiatric emergency unit. (hindawi.com)
  • To assess OST patients' self-rated physical health and healthcare seeking behaviour. (hindawi.com)
  • SLE disease activity index (SLEDAI) was used to assess the response of SLE patients to GCs treatment, and patients were classified into sensitive group and insensitive group. (springeropen.com)
  • Here we describe a case of a female patient with MDD with the co-occurrence of PTSD diagnosed in the Department of Endocrinology, where she was admitted with suspicion of adrenal insufficiency. (frontiersin.org)
  • Barriers surrounding the healthcare system seem to hinder patients to seek help through conventional healthcare, even after entering opioid substitution treatment (OST), resulting in a high level of unmet healthcare needs. (hindawi.com)
  • Neither very early nor early response predicted participation, high-intensity participation, or success at 2 years. (cdc.gov)
  • SAVER is a phase IIb open-label, randomised control trial of VPA as a chemopreventive agent in patients with high-risk oral epithelial dysplasia (OED). (biomedcentral.com)
  • One hundred and ten patients with high-risk OED will be recruited from up to 10 secondary care sites in the UK and randomised into either VPA or observation only for 4 months. (biomedcentral.com)
  • The current management options for patients with high-risk OED are limited and mostly include surgical resection and clinical surveillance. (biomedcentral.com)
  • We transcribed and descriptively coded interviews and compared responses from high- and low-retention programs. (cdc.gov)
  • Patients assigned to nivolumab had a higher overall response rate (27% vs 10%) and a longer median duration of response (32 vs 13 months) compared with the investigator's choice arm. (cancernetwork.com)
  • Food and Drug Administration (FDA)-approved pharmacological treatment for PTSD produces a response rate of approximately 60% ( 6 ). (frontiersin.org)
  • We evaluated the genetic variation in rs8099917, substitutions in core amino acid (aa) 70, and the number of aa substitutions in the interferon sensitivity-determining region (ISDR) on the prediction of sustained virological response (SVR) in treatment-naïve hepatitis C virus (HCV) genotype 1b (G1b) patients. (hindawi.com)
  • Abstract Cutaneous leishmaniasis (CL) is endemic in Aleppo and yet the knowledge, attitudes and practices (KAP) of CL patients in Aleppo has never been studied. (who.int)
  • Clinicians could benefit from employing formal mental health vital sign tracking systems because of their proven accuracy in identifying treatment failure and thereby overcoming a clinician's overly optimistic estimates of their patients' treatment responses and because of their inability to predict treatment failure, specifically negative change. (madinamerica.com)
  • Four patients receiving exercise and three receiving flexibility treatment dropped out before completion. (bmj.com)
  • Even patient preference for treatment modality was found to be associated with treatment completion, as reported in findings published i n 2017. (medscape.com)
  • conversely, the overwhelming majority of pain patients - 97% or more - never become opioid addicts. (time.com)
  • In the 42-year history of TCC, we have navigated a lot of changes in circumstance - regional alcoholism, the opioid epidemic, behavioral health redesign, the ever-growing need for wrap-around treatment, and the overdose crisis, as well as the aftermath impacting families and youth. (thecounselingcenter.org)
  • I'm delighted to welcome you to today's COCA Call "Assessment and Evidence-based Treatments for Opioid Use Disorder. (cdc.gov)
  • Initial Response to Program, Program Participation, and Weight Reduction Among 375 MOVE! (cdc.gov)
  • Very early response was defined as achieving a weight reduction of 0.5% or more at week 2, and early response was defined as achieving weight reduction of 1.0% or more at week 4. (cdc.gov)
  • Weight reduction is a challenge for health care providers and patients (1). (cdc.gov)
  • Several studies examined initial response to weight-reduction interventions as a predictor of later achievement of weight-reduction goals. (cdc.gov)
  • Initial response in these studies was defined in multiple ways, including various descriptions of weight reduction at various times (3). (cdc.gov)
  • Our findings facilitate the identification of patients at risk of severe fatigue and highlight the importance to set the reduction of fatigue as a treatment goal in CML care. (haematologica.org)
  • For their genomic analysis, the researchers used cancer cells from patients with metastatic melanoma. (cancer.gov)
  • There were no missing data and no treatment dropouts. (jmir.org)
  • Yet, there are limited treatment options and no data to suggest which treatment will work for whom. (nature.com)
  • 2] Hu C, Sale M. A joint model for nonlinear longitudinal data with informative dropout. (rug.nl)
  • A patient with MDD with the co-occurrence of PTSD was admitted to the Department of Endocrinology with suspicion of adrenal insufficiency. (frontiersin.org)
  • MDD, 296.22 [ Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision ( DSM-IV-TR )] was diagnosed, and the patient received escitalopram 20 mg/d, with no improvement after 5 weeks' treatment. (frontiersin.org)
  • Thus, the treatment changed to paroxetine 60 mg/d and trazodone 150 mg/d, which resulted in a marked improvement within 6 weeks (difficulties in starting activities remained). (frontiersin.org)
  • Participants in both VRE and PE showed similar meaningful clinical improvement with no difference between the treatment groups. (nature.com)
  • within the patient group). (findings.org.uk)
  • Of these patients, 128 patients were included in sensitive group, and 105 patients were included in insensitive group. (springeropen.com)
  • All patients will begin with weekly hour-long telephone counseling, but for patients in the AI-CBT group, those who demonstrate a significant treatment response will be stepped down through less resource-intensive alternatives including: (1) 15-minute contacts with a therapist, and (2) CBT clinician feedback provided via interactive voice response calls (IVR). (researchprotocols.org)
  • The treatment group had more women (Pearson ÷2=12.47, p=0.0004) and younger patients (Pearson ÷2=9.688, p=0.0079) than the healed group. (bvsalud.org)
  • The treated group had higher DMFT than the treatment group (Student's t p=0.003). (bvsalud.org)
  • The prognostic value of early response to treatment in addition to established predictors was analysed by multiple linear regression analyses. (bmj.com)
  • Objective To investigate the long-term effects of the tight control (TC) and conventional (CT) methotrexate-based strategies of the Computer Assisted Management in Early Rheumatoid Arthritis trial in early rheumatoid arthritis and evaluate the predictive value of an early response to treatment. (bmj.com)
  • This research supports the predictive value of very early response and early response to MOVE! (cdc.gov)
  • The aetiology of fatigue in cancer patients is multifactorial and may include adverse effects of treatment, underlying disease, metabolic and physiological abnormalities, and other variables ( Groopman, 1998 ). (nature.com)
  • (http://www.who.int/healthinfo/global_burden_disease/estimates/en/index1.html, accessed 20 March 2018). (who.int)
  • The risk of developing rheumatic heart disease is up to two times higher for females than males, and females accounted for two thirds of patients with rheumatic heart disease admitted to selected hospitals in 12 countries in the African Region, India and Yemen. (who.int)
  • As much as 30.4% of patients had orofacial complaints related to the disease. (bvsalud.org)
  • The sample consisted of 56 patients of both genders with a history of leprosy: 28 under treatment and 28 were already treated for the disease. (bvsalud.org)
  • Participants were interviewed at recruitment and then at the end of treatment to ascertain their views on access to treatment and the quality of care provided. (who.int)
  • Les participants ont été interrogés à la sélection puis à la fin du traitement pour connaître leur opinion en matière d'accès aux soins et de qualité de ceux-ci. (who.int)
  • All participants in the treatment arm consistently tolerated the highest dose. (medscape.com)
  • Participants in the treatment arm demonstrated a significant increase in sIgG4 (serum immunoglobulin G4) levels relative to control participants ( P = .046). (medscape.com)
  • A drug-induced reaction should be considered in any patient who is taking medications and who suddenly develops a symmetric cutaneous eruption. (medscape.com)
  • Ranked the #1 clinical journal covering gastroenterology and hepatology*, The American Journal of Gastroenterology (AJG) provides practical and professional support for clinicians dealing with the gastroenterological disorders seen most often in patients. (researchgate.net)
  • Furthermore, clinicians are unable to identify patients at risk of fatigue since predictors have never been assessed in this specific population of patients. (haematologica.org)
  • Failure to recognize that a patient is not responding to treatment is a serious problem in routine care and one that appears to be made worse by the clinicians' confidence in their clinical judgment and unique healing gifts. (madinamerica.com)
  • Background: Currently, medications and behavioral modifications have limited success in the treatment of functional constipation (FC). (mdpi.com)
  • Patients who completed the flexibility programme were invited to cross over to the exercise programme afterwards. (bmj.com)
  • In one example from Brazil, rheumatic fever cost the affected family annually about US$ 97/patient and cost society annually US$ 320/patient, whereas a secondary prevention programme cost US$ 23/patient annually. (who.int)