Drug DesignRadiotherapy, Computer-AssistedRadiotherapy Planning, Computer-AssistedRadiotherapy, Intensity-ModulatedRadiotherapy, Image-GuidedFiducial MarkersCone-Beam Computed TomographyRadiotherapy DosageRadiometryRadiotherapy, ConformalRadiosurgeryDose FractionationPhantoms, ImagingDrug Delivery SystemsMovementTreatment OutcomeModels, MolecularComputer-Aided DesignReproducibility of ResultsDelivery, ObstetricCrystallography, X-RayMolecular Docking SimulationLigandsStructure-Activity RelationshipQuantitative Structure-Activity RelationshipProtein ConformationBinding SitesDrug DiscoveryMolecular StructureResearch DesignProtein BindingCystine Knot MotifsAmino Acid SequenceMolecular ConformationPharmaceutical PreparationsMolecular Sequence DataDrug Evaluation, PreclinicalMolecular Dynamics SimulationPregnancyChemistry, PharmaceuticalDrug CarriersCatalytic DomainComputer SimulationProtein Structure, TertiaryHydrogen BondingCystine-Knot MiniproteinsProteinsStructural Homology, ProteinAlgorithmsSmall Molecule LibrariesProtein Structure, SecondaryModels, ChemicalAntineoplastic AgentsCyclotidesComputational BiologyEquipment DesignThermodynamicsCesarean SectionEnzyme InhibitorsTime FactorsNanoparticlesDelivery of Health CareNeoplasmsSoftwareGene Transfer TechniquesDose-Response Relationship, DrugDatabases, PharmaceuticalPeptidesSubstrate SpecificityBoranesDatabases, ProteinKineticsHydrophobic and Hydrophilic InteractionsGenetic TherapyMagnetic Resonance SpectroscopyDelayed-Action PreparationsInhibitory Concentration 50Prospective StudiesGenetic VectorsModels, BiologicalRecombinant ProteinsCrystallizationInfant, NewbornAdministration, OralLipoxygenasesInformaticsDouble-Blind MethodSequence Homology, Amino AcidNuclear Magnetic Resonance, BiomolecularCell Line, TumorHeterocyclic Compounds, 2-RingTechnology, PharmaceuticalDrug-Related Side Effects and Adverse ReactionsAntiviral AgentsHigh-Throughput Screening AssaysUser-Computer InterfaceInternetProtein EngineeringSequence AlignmentMutation