• therapeutic
  • A review of the literature regarding benzodiazepine hypnotics and Z-drugs concluded that these drugs can have adverse effects, such as dependence and accidents, and that optimal treatment uses the lowest effective dose for the shortest therapeutic time period, with gradual discontinuation in order to improve health without worsening of sleep. (wikipedia.org)
  • effects
  • In conclusion, the present study showed that modulation of the GSK3β signaling pathway might also have neuroprotective effects in tg mice by regulating APP maturation and processing and further supports the notion that GSK3β might be a suitable target for the treatment of AD. (jneurosci.org)
  • In support of a role for BMP6 in defective neurogenesis in AD, we show in an in vitro model of adult neurogenesis that treatment with amyloid-β 1-42 protein (Aβ) resulted in increased expression of BMP6, and that exposure to recombinant BMP6 resulted in reduced proliferation with no toxic effects. (jneurosci.org)
  • Long-term use of chloral hydrate is associated with a rapid development of tolerance to its effects and possible addiction as well as adverse effects including rashes, gastric discomfort and severe kidney, heart, and liver failure. (wikipedia.org)
  • 4 Cl2 + C2H5OH + H2O → Cl3CCH(OH)2 + 5 HCl Chloral hydrate is metabolized in vivo to trichloroethanol, which is responsible for its physiological and psychological effects. (wikipedia.org)
  • In the Land of Pain is a collection of notes by Alphonse Daudet chronicling the pain and suffering he experienced from tabes dorsalis, its effects on his relationships with friends, family, and other people, and the various drugs he took and physical treatments he underwent in his fight against the disease. (wikipedia.org)
  • antidotes
  • The initial evaluation and management of poisoned patients should be comprehensive and include an accurate history whenever possible, stabilization of the patient's condition, a physical assessment to evaluate the extent of poisoning and the presence of concurrent conditions, decontamination of the gastrointestinal tract using activated charcoal, gastric lavage, administration of ipecac or irrigation, poison-specific treatment with administration of antidotes when indicated and proper disposition. (aafp.org)
  • poison-specific treatment, including administration of antidotes when appropriate, and disposition. (aafp.org)
  • If the poison can be identified, reference texts or local poison control centers should be contacted to determine specific antidotes or treatments. (thefreedictionary.com)
  • Uses
  • More reputable uses of chloral hydrate include its use as a clearing agent for chitin and fibers and as a key ingredient in Hoyer's mounting medium, which is used to prepare permanent or semi-permanent microscope slides of small organisms, histological sections, and chromosome squashes. (wikipedia.org)
  • effective
  • In recent years, considerable effort has been dedicated at developing new and more effective treatments for Alzheimer's disease (AD), a leading cause of dementia in the aging population. (jneurosci.org)
  • vitro
  • In vitro studies in a model of adult neurogenesis showed that Aβ 1-42 treatment increased BMP6 expression, and recombinant BMP6 reduced cell proliferation. (jneurosci.org)
  • Although preliminary studies have shown DCA can slow the growth of certain tumors in animal studies and in vitro studies, as of 2012 there is insufficient evidence to support the use of DCA for cancer treatment. (wikipedia.org)
  • Although preliminary studies have shown DCA can slow the growth of certain tumors in animal studies and in vitro studies, the American Cancer Society stated that "available evidence does not support the use of DCA for cancer treatment at this time . (wikipedia.org)
  • dementia
  • While physiological stress factors vary from person to person, aromatherapy results in a significant decrease in stress and anxiety levels in patients.Lavender oil is a potential treatment for agitated behavior in patients with dementia through application via aromatherapy. (wikipedia.org)
  • patients
  • [ 2 , 18 ] In a systematic review of pharmacologic therapy for persistent/intractable hiccups in 341 patients in 15 studies, Steger et al noted that treatment of the underlying condition was the most successful, but there were no high-quality data to allow pharmacologic treatment recommendations. (medscape.com)
  • Because primary care physicians are frequently the health care professionals first contacted by patients who have ingested poisons, knowledge of the proper initial evaluation and treatment of these patients is essential. (aafp.org)
  • The plasma, serum or blood concentrations of chloral hydrate and/or trichloroethanol, its major active metabolite, may be measured to confirm a diagnosis of poisoning in hospitalized patients or to aid in the medicolegal investigation of fatalities. (wikipedia.org)
  • At present, FD patients can be expected to function independently if treatment is begun early and major disabilities avoided. (wikipedia.org)
  • All five patients were receiving other treatments during the study. (wikipedia.org)
  • blood
  • The pathophysiology of vascular headaches, especially migraine, is thought to be related to dilation of these cerebral blood vessels, so drugs that act to constrict them are used in the treatment of these problems. (wikipedia.org)
  • found
  • Prior to World War II, ethyl carbamate saw relatively heavy use in the treatment of multiple myeloma before it was found to be toxic, carcinogenic, and largely ineffective. (wikipedia.org)
  • given
  • The end of the treatment was marked by the abundance of stools and then castor oil was given to the patient as a further purgative. (wikipedia.org)
  • Symptoms
  • For the treatment of rheumatoid arthritis, strategies have shifted from controlling symptoms (such as nonsteroidal anti-inflammatory drugs and corticosteroids) to restraint the disease process with the suppression of immune system (the usage of disease-modifying antirheumatic drugs (DMARDs) and biologic agents) [ 1 ]. (hindawi.com)
  • least
  • therefore, the overall unpredictability necessitates either pre-planned hospitalization, treatment coordinated with a doctor, or at the very least rapid access to medical care, and a supporting system of friends or family should be introduced prior to addressing detoxification. (wikipedia.org)
  • drugs
  • Chloral hydrate has not been approved by the FDA in the United States or the EMA in the European Union for any medical indication and is on the list of unapproved drugs that are still prescribed by clinicians. (wikipedia.org)
  • discuss
  • What should I discuss with my health care provider before using chloral hydrate rectal? (drugs.com)
  • Elliott, I am going to explore the definition of amblyopia and discuss the rationale behind amblyopia treatment before going on to discuss how binary option demo account tional treatment concepts should be modified in the light of recent work on the subject. (thebestforextraining.com)
  • For those seeking addiction treatment for themselves or a loved one, our caring advisors are standing by to discuss your treatment options. (sobercollege.com)
  • Diet
  • The week following the treatment a diet of a special tonic and simple and easy to digest meals would relax the patient. (wikipedia.org)
  • chemical
  • Both DCA and TCA are used for cosmetic treatments (such as chemical peels and tattoo removal) and as topical medication for the chemoablation of warts, including genital warts. (wikipedia.org)
  • different
  • The following statement from the Mayo Clinic, though made in 1932, still describes the situation perfectly: "The amount of knowledge on any subject such as this can be considered as being in inverse proportion to the number of different treatments suggested and tried for it. (medscape.com)
  • He describes the different physical treatments he underwent, including being suspended in the air, diets, and a variety of injections. (wikipedia.org)
  • available
  • A Cochrane review concluded that the available evidence was insufficient to guide treatment of persistent or intractable hiccups by either pharmacologic or nonpharmacologic means. (medscape.com)
  • sometimes
  • Congress has sometimes scheduled other substances through legislation such as the Hillory J. Farias and Samantha Reid Date-Rape Prevention Act of 2000, which placed gamma hydroxybutyrate in Schedule I. Classification decisions are required to be made on criteria including potential for abuse (an undefined term), currently accepted medical use in treatment in the United States, and international treaties. (wikipedia.org)
  • cell
  • Treatment with HEM reduced MPTP-induced dopaminergic cell loss, apoptotic cell death induced by oxidative stress, as well as the level of glutathione, nitrotyrosine and 4-hydroxy-2-nonenal (4-HNE). (biomedcentral.com)