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  • hematologic
  • Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) is caused by exposure to certain medications that may result in a rash, fever, inflammation of internal organs, lymphadenopathy, and characteristic hematologic abnormalities such as eosinophilia, thrombocytopenia, and atypical lymphocytosis. (wikipedia.org)
  • DRESS syndrome is one of several terms that have been used to describe a severe idiosyncratic reaction to a drug that is characterized by a long latency of onset after exposure to the offending medication, a rash, involvement of internal organs, hematologic abnormalities, and systemic illness. (wikipedia.org)
  • toxins
  • 153 154 155 Used to correct marked neurologic effects (e.g., seizures, coma) induced by methylhydrazine (produced by hydrolysis of the toxins in these mushrooms). (drugs.com)
  • Pulmonary
  • Pulmonary stenosis and left-to-right shunt through the ductus), it may be advisable to improve oxygenation by maintaining the ductus open with prostaglandin treatment. (wikipedia.org)
  • 10% on CBC mononeuropathy or polyneuropathy migratory or transient pulmonary opacities on chest x-ray (CXR) paranasal sinus abnormalities vessel biopsy showing eosinophils in extravascular areas Microscopic polyarteritis/polyangiitis. (wikipedia.org)
  • It has also been used to prevent and treat race horses for exercise-induced pulmonary hemorrhage. (wikipedia.org)
  • autoimmune
  • Cyclophosphamide decreases the immune system's response, and although concerns about toxicity restrict its use to patients with severe disease, it remains an important treatment for life-threatening autoimmune diseases where disease-modifying antirheumatic drugs (DMARDs) have been ineffective. (wikipedia.org)
  • chemotherapy
  • both were exposed to chemotherapy and delivered prematurely, but both deaths were thought not to be related to treatment. (biomedsearch.com)
  • Lapatinib, in combination with an aromatase inhibitor (AI), is indicated for the treatment of post-menopausal women with hormone receptor (HR)-positive, HER2 (ErbB2) over-expressing metastatic breast cancer and for whom chemotherapy is currently not intended. (gsk.com)
  • The main use of cyclophosphamide is with other chemotherapy agents in the treatment of lymphomas, some forms of brain cancer, neuroblastoma, leukemia and some solid tumors. (wikipedia.org)
  • Adverse drug reactions from cyclophosphamide are related to the cumulative medication dose and include chemotherapy-induced nausea and vomiting, bone marrow suppression, stomach ache, hemorrhagic cystitis, diarrhea, darkening of the skin/nails, alopecia (hair loss) or thinning of hair, changes in color and texture of the hair and lethargy. (wikipedia.org)
  • Disorders
  • Of course, drugs can exacerbate the bleeding in patients with pre-existing bleeding disorders. (renalandurologynews.com)
  • Interestingly, most conventional medical practice appears to have very little interest in investigating medically induced causes of disorders and finding ways to remove them. (homeopathicassociates.com)
  • Genetic factors and mental disorders can contribute to the severity of drug addiction. (wikipedia.org)
  • And agonists of the MC4 receptor such as melanotan II and PF-00446687, via activation of the central oxytocin system, have been found to promote pair bond formation in prairie voles and, due to these prosocial effects, have been suggested as possible treatments for social deficits in autism spectrum disorders and schizophrenia. (wikipedia.org)
  • insulin
  • Other stimulation tests for adrenal insufficiency which are used in non-critical patients, such as the test using metyrapone or a test which employs insulin to induce hypoglycemia, are not preferred for CIRCI. (wikipedia.org)
  • In accordance with the above, MC4 receptor agonists have garnered interest as potential treatments for obesity and insulin resistance, while MC4 receptor antagonists have attracted interest as potential treatments for cachexia. (wikipedia.org)
  • Interactions
  • Therefore, understanding the interactions between viral proteins and host cell proteins is very important to develop drugs for these liver diseases and HCC. (hindawi.com)
  • These drug interactions with fenofibrate are considered major and may need therapy modifications: Bile acid sequestrants (e.g. cholestyramine, colestipol, etc. (wikipedia.org)
  • cardiovascular
  • However, due to lack of cardiovascular benefit in several large trials and the risk of side effects such as muscle damage, the FDA withdrew approval for the use in high cholesterol treatment in combination with statins. (wikipedia.org)
  • Prevent
  • Awareness of medication-induced torsade de pointes and a preset protocol for treating it could save lives in the hospital with swift action to prevent cardiac arrest, according to a joint statement from two professional associations. (medpagetoday.com)
  • liver
  • Patients with other acquired conditions that put them at higher risk of bleeding (uremia, liver disease, thrombocytopenia) often have an increased bleeding or change in the pattern of the bleeding when initiating drugs that interfere with platelet function. (renalandurologynews.com)
  • On the other hand, if the virus dominates by evolving quasispecies which code for altered proteins that interact differently with host proteins, or induce mutations in host protooncogenes, then the patient may develop liver cirrhosis and/or liver cancer. (hindawi.com)
  • acetylcysteine for acetaminophen-induced liver injury. (uspharmacist.com)
  • LiverTox (https://livertox.nih.gov) is a clinical and research database developed by the National Institute of Diabetes and Digestive and Kidney Diseases, the National Library of Medicine, and the Drug-Induced Liver Injury Network (DILIN) study group to provide up-to-date, comprehensive clinical information on DILI. (uspharmacist.com)
  • Prevention
  • Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. (elsevier.com)
  • Additionally
  • Additionally, hemodialysis should not be considered as an overdose treatment option because fenofibrate heavily binds to plasma proteins and does not dialyze well. (wikipedia.org)
  • supplements
  • Always obtain a good medication history (prescription, over the counter, herbs and other supplements that patients do not consider as drugs) in every bleeding patient. (renalandurologynews.com)
  • patients
  • It is also contraindicated in patients with suspected or established subcortical brain damage, with or without hypothalamic damage, since a hyperthermic reaction with temperatures in excess of 40°C may occur in such patients, sometimes not until 14 to 16 hours after drug administration. (mentalhealth.com)
  • Although the prevalence of the syndrome appears to be highest among the elderly, especially elderly women, it is impossible to rely upon prevalence estimates to predict, at the inception of neuroleptic treatment, which patients are likely to develop the syndrome. (mentalhealth.com)
  • However, some patients may require treatment despite the presence of the syndrome. (mentalhealth.com)
  • Patients will be randomized to Telintra or enter an observation period with an option to crossover to Telintra treatment in a 1:1 allocation. (clinicaltrials.gov)
  • Note that the statement did not specify the details for monitoring cardiac rhythm in patients at risk for drug-induced torsade de pointes but did recommend having a protocol in place. (medpagetoday.com)
  • These cases "should be avoidable" with consistent electrocardiographic monitoring of patients receiving drugs known to prolong the QT interval, the American Heart Association and American College of Cardiology wrote in a statement endorsed by the American Association of Critical-Care Nurses. (medpagetoday.com)
  • In patients with severely depressed cardiac output and recent-onset atrial fibrillation, immediate electrical cardioversion is the treatment of choice. (aafp.org)
  • This rhythm abnormality affects 3 to 5 percent of patients more than 60 years of age 1 and becomes increasingly common with advancing age. (aafp.org)
  • 4 The mortality rate for stroke in patients with atrial fibrillation is approximately twice as high as the rate in patients without this rhythm abnormality. (aafp.org)
  • 5 Although anticoagulation is contraindicated in some elderly patients, a study in Great Britain 6 found that about 60 percent of patients identified in community screenings as having atrial fibrillation were eligible for, and would benefit from, this treatment. (aafp.org)
  • Growth
  • First trimester exposure to cyclophosphamide for the treatment of cancer or lupus displays a pattern of anomalies labeled "cyclophosphamide embryopathy," including growth restriction, ear and facial abnormalities, absence of digits and hypoplastic limbs. (wikipedia.org)
  • diagnosis
  • Other important considerations in the differential diagnosis include central anticholinergic toxicity, heat stroke, drug fever and primary CNS pathology. (mentalhealth.com)
  • Platelet function testing with light transmission aggregometry (LTA), the platelet function analyzer (PFA-100), or a template bleeding time may reveal abnormalities that support the diagnosis. (renalandurologynews.com)
  • medications
  • When initial medications are ineffective, radiofrequency ablation of ectopic sites is an increasingly popular treatment option. (aafp.org)
  • 11-14 Another drug reference list, DILIrank, contains information on 1,036 FDA-approved medications ranked according to their potential to cause DILI. (uspharmacist.com)
  • Administration of medications that also treat multiple seizure types is usually the most effective form of treatment. (wikipedia.org)
  • arrhythmia
  • If the arrhythmia is long-standing and the patient is not a suitable candidate for rate cardioversion, initial treatment should focus on ventricular rate control, with consideration given to long-term stroke prophylaxis. (aafp.org)
  • receptor
  • EP4 is the major receptor associated with PGE2-induced dilation of the DA and can be found across the DA in smooth muscle cells. (wikipedia.org)
  • The non-selective melanocortin receptor agonist afamelanotide (NDP-α-MSH) has been found to induce brain-derived neurotrophic factor (BDNF) expression in the rodent brain via activation of the MC4 receptor and mediate "intense" neurogenesis and cognitive recovery in an animal model of Alzheimer's disease. (wikipedia.org)
  • Etomidate
  • Treatment with imidazole drugs such as etomidate, ketoconazole and miconazole can also suppress the HPA axis, as well as drugs used specifically for this purpose, such as metyrapone. (wikipedia.org)
  • 2000
  • Building on his work, research both in China and the West eventually led to the development of the drug Trisenox by PolaRx Biopharmaceuticals, Inc through NDA, which was approved for leukemia treatment by the US FDA in 2000 and subsequently marketed and sold by Cell Therapeutics, Inc., before being acquired by Cephalon. (wikipedia.org)
  • Clinical
  • While this confirms clinical observations by many homeopaths, more research is needed to investigate whether and how tautopathic treatment can counteract all of the above conditions. (homeopathicassociates.com)
  • cardiac
  • Findings from physical examinations, including basic systems of cardiac and respiratory, the affected systems, possible involvement of other systems, pertinent normal findings and abnormalities. (wikipedia.org)
  • exposure
  • The symptoms of DRESS syndrome usually begin several weeks after exposure to the offending drug. (wikipedia.org)
  • Intermittent dosing of cyclophosphamide decreases cumulative drug dose, reduces bladder exposure to acrolein and has equal efficacy to daily treatment in the management of lupus nephritis. (wikipedia.org)
  • Despite the importance of numerous psychosocial factors, at its core, drug addiction involves a biological process: the ability of repeated exposure to a drug of abuse to induce changes in a vulnerable brain that drive the compulsive seeking and taking of drugs, and loss of control over drug use, that define a state of addiction. (wikipedia.org)
  • outpatient
  • Administration in the hospital is more likely to be associated with torsade de pointes than is treatment of an outpatient population with the same drug, Drew's group noted. (medpagetoday.com)
  • patient
  • data were collected retrospectively if the patient was diagnosed before April, 2003 (when the registry began), or prospectively thereafter, irrespective of the outcome of pregnancy and the type and timing of treatment. (biomedsearch.com)
  • Both the risk of developing the syndrome and the likelihood that it will become irreversible are believed to increase as the duration of treatment and the total cumulative dose of neuroleptic drugs administered to the patient increase. (mentalhealth.com)
  • If a patient requires antipsychotic drug treatment after recovery from NMS, the potential reintroduction of drug therapy should be carefully considered. (mentalhealth.com)
  • Patient, environmental, and drug-related factors may play a role in the pathogenesis of DILI. (uspharmacist.com)
  • Additional symptoms (un/related or significant symptoms to the chief complaint) Treatment (has the patient seen another provider for this symptom? (wikipedia.org)
  • common
  • Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. (elsevier.com)
  • Persistence of the ductus may be associated with other abnormalities, and is much more common in females. (wikipedia.org)
  • Treatment of behavioural problems or psychosis due to dementia with antipsychotics is common, but not usually recommended, as there is little benefit with an increased risk of early death. (wikipedia.org)
  • profound
  • Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death [see WARNINGS , DRUG INTERACTIONS ]. (rxlist.com)
  • Mechanical stress due to pressure and volume overload and metabolic dysfunction also induce profound changes in ECM composition that contribute to the pathogenesis of heart failure. (jci.org)
  • By the 1890s, the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. (wikipedia.org)
  • Acute
  • Injected epinephrine proved to be especially efficacious for the acute treatment of asthma attacks, and an inhaled version was sold in the United States until 2011 (Primatene Mist). (wikipedia.org)
  • Efficacy
  • The safety and efficacy of zoledronic acid in the treatment of hypercalcemia associated with hyperparathyroidism or with other non-tumor-related conditions has not been established. (whatismedicalinsurancebilling.org)
  • However, a systematic review concluded that compared with other anxiolytic agents (benzodiazepines and buspirone), hydroxyzine was equivalent in efficacy, acceptability, and tolerability, however there is insufficient evidence to recommend it as a treatment for generalised anxiety disorder due to the high risk of bias in the reviewed studies. (wikipedia.org)
  • They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs. (wikipedia.org)
  • fortunately recent trials have been published about the safety and efficacy of current treatment options. (wikipedia.org)
  • diabetes
  • People with diabetes can benefit from education about the disease and treatment, good nutrition to achieve a normal body weight, and exercise, with the goal of keeping both short-term and long-term blood glucose levels within acceptable bounds. (diabeteshelpcare.com)
  • rarely
  • Macropsia has a wide range of causes, from prescription and illicit drugs, to migraines and (rarely) complex partial epilepsy, and to different retinal conditions, such as epiretinal membrane. (wikipedia.org)
  • sedation
  • citation needed] In other cases, the usage of hydroxyzine is as a form of non-barbiturate tranquilizer used in the pre-operative sedation and treatment of neurological disorders, such as psychoneurosis and other forms of anxiety or tension states. (wikipedia.org)
  • placebo
  • Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. (nih.gov)
  • Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about 4.5%, compared to a rate of about 2.6% in the placebo group. (nih.gov)
  • These figures cannot be compared with those obtained from other clinical studies involving related drug products and placebo, as each group of drug trials is conducted under a different set of conditions. (rxlist.com)
  • therapeutic
  • Even though it is an effective sedative, hypnotic, and anxiolytic, it shares virtually none of the abuse, dependence, addiction, and toxicity potential of other drugs used for the same range of therapeutic reasons. (wikipedia.org)
  • different
  • Treatment with tube had no different aetiological turn on mcr. (eyfel.de)
  • Treatment is radically different for idiopathic granulomatous mastitis and other granulomatous lesions of the breast, the precise diagnosis is therefore very important. (wikipedia.org)
  • clinical
  • Two days after Pfizer announced its plans for the drug, it ended the Phase III clinical trial due to higher rates of chest pain and heart failure and a 60 percent increase in overall mortality. (wikipedia.org)
  • group
  • Very, the charcoal eye is insignificantly ophtalmic for the fatigue of group on price physical volunteers possible as treatment. (eyfel.de)
  • LY-341,495 and MGS-0039 are drugs that act as a selective antagonist blocking both of the group II metabotropic glutamate receptors, mGluR2 and mGluR3. (wikipedia.org)
  • Earlier, a group at Bayer, a drug company, successfully repeated only one fourth of 67 important papers. (wikipedia.org)
  • cells
  • They then use this information to research how to change human iPS cells (induced pluripotent stem cells) into cell types that are useful for investigating human cell biology and disease. (wikipedia.org)
  • successfully
  • A Randomized, Controlled, Open-Label, 48-Week Study of Continuing Successfully Suppressive Treatment in HIV-1 Infected Adults With First-Line Twice-Daily Zidovudine and Lamivudine-Based Regimens Versus Pro-actively Replacing of Zidovudine and Lamivudine by Once-Daily Emtricitabine and Tenofovir Disoproxil Fumarate to Prevent Progression of or Reverse Peripheral Lipoatrophy. (clinicaltrials.gov)
  • blood
  • The blood pressure raising and vasoconstrictive effects of adrenal extracts were of particular interest to surgeons as hemostatic agents and as treatment for shock, and a number of companies developed products based on adrenal extracts containing varying purities of the active substance. (wikipedia.org)
  • systematic
  • About coloplast coloplast is a growing difference and friend of the prednisolone use in eyes hospital, mail said this systematic steroid of alert tibiae in the patient treatment. (eyfel.de)
  • symptoms
  • Chronic symptoms are well described and are known as post-treatment Lyme disease syndrome, often called chronic Lyme disease. (wikipedia.org)
  • Symptoms caused chemically by drugs such as cannabis, magic mushrooms, or cocaine tend to dissipate after the chemical compound has been excreted from the body. (wikipedia.org)
  • known
  • Effexor XR is indicated for the treatment of Social Anxiety Disorder (SAD), also known as social phobia . (rxlist.com)
  • discovery
  • Rational drug discovery from plants started particularly with the isolation of morphine, analgesic and sleep-inducing agent from opium, by the German apothecary assistant Friedrich Sertürner, who named the compound after the Greek god of dreams, Morpheus. (wikipedia.org)
  • In 1903, Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. (wikipedia.org)
  • develop
  • Despite appropriate treatment, about 10 to 20% of people develop joint pains, memory problems, and feel tired for at least six months. (wikipedia.org)
  • Some people develop a fever and muscle and joint pains from treatment which may last for one or two days. (wikipedia.org)
  • Effects
  • An in-depth review of the most highly cited biomarkers (whose presence are used to infer illness and measure treatment effects) claimed that 83 percent of supposed correlations became significantly weaker in subsequent studies.Homocysteine is an amino acid whose levels correlated with heart disease. (wikipedia.org)
  • The drug proved to have only modest anti-asthma effects, but produced sensations of exhilaration and palpitations. (wikipedia.org)
  • major
  • Effexor XR (venlafaxine hydrochloride) extended-release capsules are indicated for the treatment of major depressive disorder (MDD). (rxlist.com)
  • oral
  • A structurally similar compound, ephedrine, (actually more similar to norepinephrine,) was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthma. (wikipedia.org)
  • thus
  • On the other hand, IGM is usually diagnosed only after complications and referral to a secondary breast care center so light cases may resolve spontaneously or after symptomatic treatment and thus never be diagnosed as IGM. (wikipedia.org)
  • food
  • This drug/food mixture should be swallowed immediately without chewing and followed with a glass of water to ensure complete swallowing of the pellets (spheroids). (rxlist.com)
  • However
  • Comparison of the cited figures, however, can provide the prescriber with some basis for estimating the relative contributions of drug and nondrug factors to the untoward event incidence rate in the population studied. (rxlist.com)
  • however, this is not believed to be true, due to the inability to detect infectious organisms after standard treatment. (wikipedia.org)
  • potential
  • Torcetrapib was originally hyped as a drug that could block a protein that converts HDL cholesterol into LDL with the potential to "redefine cardiovascular treatment. (wikipedia.org)
  • role
  • The first of these were local apothecaries that expanded from their traditional role distributing botanical drugs such as morphine and quinine to wholesale manufacture in the mid 1800s. (wikipedia.org)