AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentInformation ScienceHealth Care
MyocarditisCoxsackievirus InfectionsEnterovirus B, HumanAutoimmune DiseasesMyocardiumEnterovirus InfectionsCardiomyopathy, DilatedChagas CardiomyopathyEnterovirusAcute DiseaseCardiovirus InfectionsEncephalomyocarditis virusRats, Inbred LewCardiac MyosinsEndocardiumBiopsyReoviridae InfectionsPericarditisMyosinsVirus DiseasesHeartCardiomyopathiesGiant CellsEdema, CardiacMice, Inbred BALB CDisease Models, AnimalTrypanosoma cruziParvovirus B19, HumanFatal Outcome
Fulminant myocarditisInflammationGiant cell myocarditisVaccinationRisk of myocarditisSymptomsAcute myocarditisCases of myocarditis and pericarditisSevere2023Causes of myocarditisPericarditis and myocarditisCardiomyopathyViral infectionClinicalCardiacEosinophilic myocarditisInfection2021TherapeuticPatientsInfectionsIncidenceDisseminated intravascul2022ComplicationsCorticosteroidsEtiologyInfectiousPfizerOutcomesRegimensOnsetImmuneChagasChestCohortChemotherapyAdjuvant TreatmentUncommonMRNA vaccinesImmunosuppressive therapyMyocardial
Fulminant myocarditis6
  • Fulminant myocarditis is defined as sudden and severe myocarditis that is associated with signs and symptoms of heart failure while at rest. (wikipedia.org)
  • More specifically, fulminant myocarditis is characterized by a distinct, rapid onset of severe heart failure symptoms, such as shortness of breath and chest pain, that develop over the course of hours to days. (wikipedia.org)
  • Acute non-fulminant myocarditis has a less distinct onset in contrast to fulminant myocarditis, and evolves over days to months. (wikipedia.org)
  • While the symptoms of acute myocarditis overlap with those of fulminant myocarditis, they do not typically occur at rest, and treatment does not require the use of mechanical circulatory support. (wikipedia.org)
  • Giant cell myocarditis (GCM) is a rare and commonly fatal form of fulminant myocarditis. (hindawi.com)
  • Moreover, new perspectives are emerging in terms of clinical, non-invasive diagnosis through Cardiac Magnetic Resonance (CMR) and treatment to favor the spontaneous resolution of fulminant myocarditis, by putting the heart temporarily at rest with Extra Corporeal Membrane Oxygenation (ECMO). (mdpi.com)
Inflammation14
  • Myocarditis is inflammation of the heart muscle. (medlineplus.gov)
  • Myocarditis, also known as inflammatory cardiomyopathy, is an acquired cardiomyopathy due to inflammation of the heart muscle. (wikipedia.org)
  • The signs and symptoms associated with myocarditis are varied, and relate either to the actual inflammation of the myocardium or to the weakness and dysfunction of the heart muscle that is secondary to the inflammation. (wikipedia.org)
  • Post-marketing surveillance of Pfizer's and Moderna's COVID vaccination has identified a possible association between its use and subsequent episodes of myocarditis and pericarditis - two forms of heart inflammation. (acsh.org)
  • Myocarditis is an inflammation of the middle layers of the heart's wall, and it too causes pain and may lead to the heart failing its function in fully circulating our blood. (acsh.org)
  • Brighton defined three levels of certainty associated with myocarditis and pericarditis: Level 1, a definite case, confirmed biopsy or MRI, Level 2, and Level 3, a possible case, based upon symptoms, an abnormal EKG, and some biomarkers of inflammation not of cardiac injury (e.g., c-reactive protein). (acsh.org)
  • Myocarditis is a general term for inflammation of the heart muscle. (uvmhealth.org)
  • If we are concerned about myocarditis, we can run specific lab tests to determine if the heart has been injured or if the body is demonstrating a very high level of inflammation. (uvmhealth.org)
  • There have been rare reports of people-particularly male adolescents and young adults-who received the mRNA vaccines (Pfizer/BioNTech & Moderna) and experienced symptoms of myocarditis or pericarditis (heart inflammation conditions) within several days of getting their shot. (utah.edu)
  • In very rare cases, inflammatory diseases of the heart may occur following vaccination with Pfizer or Moderna: myocarditis (inflammation of the heart muscle) or pericarditis (inflammation of the outer lining of the heart). (rivm.nl)
  • An unusual spike in the number of newborns in the U.K. developing myocarditis - inflammation of the heart muscle - is fueling online misinformation about COVID-19 vaccines. (politifact.com)
  • In very young babies, enterovirus can, on rare occasions, lead to a severe complication called myocarditis - which causes inflammation of the heart," Ladhani said. (politifact.com)
  • COVID-19 can sometimes lead to myocarditis , an inflammation of the heart muscle. (kidshealth.org)
  • Myocarditis is inflammation of the muscle tissue of the heart (myocardium) that causes tissue death. (msdmanuals.com)
Giant cell myocarditis12
  • Giant cell myocarditis (GCM) is a rare and frequently fatal disorder with no proven treatment. (nih.gov)
  • Rare causes of specific inflammatory cardiomyopathies include cardiac sarcoidosis, giant cell myocarditis and eosinophilic myocarditis. (intechopen.com)
  • In patients with cardiac sarcoidosis, giant cell myocarditis or eosinophilic myocarditis the use of immunosuppressive treatment is recommended, as is the case in myocarditis associated with autoimmune disorders. (intechopen.com)
  • Giant cell myocarditis (GCM) is a rare clinical condition characterized by rapid compromise of cardiac systolic function, ultimately leading to severe cardiogenic shock. (hindawi.com)
  • MyMediTravel currently has no pricing information available for Giant Cell Myocarditis Treatment procedures in Philippines. (mymeditravel.com)
  • Costa Medica Healthcare and Diagnostic Center, located in Rosario, Cavite, Philippines offers patients Giant Cell Myocarditis Treatment procedures among its total of 162 available procedures, across 2 different specialties. (mymeditravel.com)
  • Currently, there's no pricing information for Giant Cell Myocarditis Treatment procedures at Costa Medica Healthcare and Diagnostic Center, as all prices are available on request only. (mymeditravel.com)
  • Then you should expect to rest for a few more days before you begin to commence light activity again - remember, Giant Cell Myocarditis Treatment is a major surgery and your body needs time to recover. (mymeditravel.com)
  • The success rate for Giant Cell Myocarditis Treatment in Philippines is now extremely high given the recent advances in medical technology and surgeon experience. (mymeditravel.com)
  • Giant cell myocarditis is a rare, severe form of myocarditis that has a rapid onset. (msdmanuals.com)
  • In people with giant cell myocarditis, the heart is suddenly unable to pump enough blood to support the body's functions (called cardiogenic shock). (msdmanuals.com)
  • Giant cell myocarditis has a poor prognosis but immunosuppressive therapy can help improve survival. (msdmanuals.com)
Vaccination8
  • COVID myocarditis: immune reaction to vaccination or a settlement of the coronavirus within the myocardium? (mdpi.com)
  • An increasing number of myocarditis/pericarditis incidences has been reported after coronavirus disease-19 (COVID-19) vaccination in adolescents and young adults. (mdpi.com)
  • Myocarditis and Vaccination: Is It Worth the Risk? (uvmhealth.org)
  • Researchers stressed that the risks are small, and that the benefit of vaccination far outweighs concerns about myocarditis. (tctmd.com)
  • Two new research letters and one case report, published in Circulation this week, are highlighting the temporal association between vaccination for COVID-19 and the onset of myocarditis, a rare side effect that has the attention of regulators in the United States, Europe, and elsewhere. (tctmd.com)
  • With myocarditis being an extremely rare adverse event, he stressed, the benefits of vaccination continue to far outpace the risks. (tctmd.com)
  • The reports indicate that the cases of myocarditis and pericarditis mostly started within the first fourteen days after vaccination, and were more likely to occur after the second vaccination than after the first. (rivm.nl)
  • Those cases, which were often mild and responded to treatment, most frequently occurred in adolescent and young adult men within seven days of receiving the second dose of an mRNA vaccination, the CDC reported . (politifact.com)
Risk of myocarditis3
  • The FDA and European Medicines Agency estimates the risk of myocarditis after the Covid-19 vaccine as 1 case per 100,000 of those who are vaccinated. (wikipedia.org)
  • Are adolescents at risk of myocarditis if they get the COVID-19 vaccine? (uvmhealth.org)
  • Even though the CDC and the European Medicines Agency are continuing to monitor the number of reported cases, experts stressed that vaccination's benefits exceed the relatively small risk of myocarditis. (tctmd.com)
Symptoms13
  • Myocarditis can be hard to diagnose because the signs and symptoms often mimic those of other heart and lung diseases, or a bad case of the flu. (medlineplus.gov)
  • Contact your provider if you have symptoms of myocarditis, especially after a recent infection. (medlineplus.gov)
  • Additionally, myocarditis is often associated with pericarditis, and many people with myocarditis present with signs and symptoms that suggest myocarditis and pericarditis at the same time. (wikipedia.org)
  • Myocarditis can be distinguished as either fulminant or acute based on the severity of symptoms on presentation, as well as the time course over which symptoms develop and persist. (wikipedia.org)
  • Thus, treatment is generally initiated when symptoms become clinically significant or progressive. (medscape.com)
  • If symptoms of myocarditis occur, always contact a doctor. (rivm.nl)
  • Doctors have made progress developing treatments to reduce symptoms and prolong life, but there is no cure. (mountsinai.org)
  • Treatment involves a combination approach to treat the immune response, improve circulation, and stop the progression of skin symptoms. (mountsinai.org)
  • But some children with more serious symptoms (such as those with MIS-C) need treatment in a hospital. (kidshealth.org)
  • What are symptoms of myocarditis? (sott.net)
  • When children develop myocarditis, some signs and symptoms can include fever, fainting, difficulty in breathing, rapid breathing, and rapid or abnormal heart rhythms. (sott.net)
  • Mayo Clinic doctors say treatment focuses on the cause of the condition and symptoms, such as heart failure and shortness of breath. (sott.net)
  • Specific symptoms and severity of AGS vary among persons, and no treatment or cure is currently available. (cdc.gov)
Acute myocarditis3
  • Myocardial hyperemia assessment by contrast-enhanced first-pass MRI can be used as a quick diagnostic tool in patients with acute myocarditis. (medscape.com)
  • In 2013, about 1.5 million cases of acute myocarditis occurred. (wikipedia.org)
  • Diagnosis and risk stratification in patients presenting with acute myocarditis is especially challenging due to the great heterogeneity of clinical presentation. (medsci.org)
Cases of myocarditis and pericarditis1
  • Based on data from the Vaccine Adverse Event Reporting System (VAERS) , there have been roughly 475 cases of myocarditis and pericarditis in people ages 30 years and younger. (tctmd.com)
Severe9
  • We describe a 47-year-old man with severe acute heart failure due to GCM in whom the left ventricular ejection fraction normalized and the myocardial inflammatory infiltrate resolved rapidly after treatment with muromonab-CD3, cyclosporine, azathioprine, and corticosteroids. (nih.gov)
  • In severe cases, treatment with mechanical circulatory support and/or heart transplantation may be required. (intechopen.com)
  • Our case highlights the value of this novel, flexible, and disposable device for hemodynamic monitoring, accurate therapy guidance, and potential VA-ECMO weaning process of patients with this form of severe myocarditis. (hindawi.com)
  • Despite this approach and consistent with other severe irAEs, patients often do not have improvement or resolution of myocarditis and require additional treatment with other agents. (nature.com)
  • A March 3, 2023, MMWR provides updated clinical treatment considerations about using therapeutics to treat severe mpox cases, including ocular infections, neurologic complications, myopericarditis, complications associated with mucosal lesions, and complications from uncontrolled viral spread. (cdc.gov)
  • For patients at high risk for progression to severe disease, treatment should be administered early in the course of illness along with supportive care and pain control. (cdc.gov)
  • The study results may inform treatment and prevention of severe illness and deaths associated with mpox in people with advanced HIV. (cdc.gov)
  • It was immediately followed by a Zero Hedge headline that read: "WHO Warns Of 'Unusual' Surge in Severe Myocarditis in Babies. (politifact.com)
  • The reported increase in severe myocarditis associated with enterovirus infection among newborns was unusual, the WHO reported . (politifact.com)
20234
  • Cite this: FDA OKs Pembrolizumab for Adjuvant Treatment of NSCLC - Medscape - Jan 27, 2023. (medscape.com)
  • Reference: "A long-term follow-up of treatment for young children with obesity: a randomized controlled trial" by Anna Ek, Markus Brissman, Karin Nordin, Karin Eli and Paulina Nowicka, 25 October 2023, International Journal of Obesity . (scitechdaily.com)
  • Between June 2022 and April 2023 in Wales, 10 newborns under 28 days old developed myocarditis associated with infections from enterovirus, some of the most prevalent viruses in the world, according to the World Health Organization and the Welsh minister for health and social services. (politifact.com)
  • From June 2022 to April 2023 in Wales, 10 newborns younger than 28 days old who were hospitalized and tested positive for enterovirus infections also developed myocarditis, according to the WHO . (politifact.com)
Causes of myocarditis2
Pericarditis and myocarditis1
Cardiomyopathy4
  • The most common cause of inflammatory cardiomyopathy is lymphocytic myocarditis, which is most usually triggered by a viral infection, and occasionally by other infectious agents. (intechopen.com)
  • The pathogenetic mechanisms of viral myocarditis as a cause of cardiomyocyte death, evolving towards dilated cardiomyopathy. (mdpi.com)
  • The ACC's Accelerating Innovation for Medical Excellence in Hypertrophic Cardiomyopathy (AIME HCM) initiative is designed to amplify education, research efforts, clinical guidance and practical tools to increase awareness and understanding of hypertrophic cardiomyopathy and optimize treatment and outcomes. (acc.org)
  • Heart failure can occur at all ages and result from many different forms of heart disease, including congenital heart disease, cardiomyopathy , myocarditis and cardiotoxicity. (choa.org)
Viral infection3
  • Myocarditis is most often due to a viral infection. (wikipedia.org)
  • In its statement, the WHO said that the most common cause of myocarditis is viral infection, including infection from enteroviruses, which are among the world's most prevalent class of viruses. (politifact.com)
  • In the United States and most other developed nations, infectious myocarditis is most often caused by a viral infection. (msdmanuals.com)
Clinical11
  • Patients in Europe with MSI-H/dMMR colorectal cancer have had only chemotherapy-containing regimens available to them in the first-line treatment setting and have historically faced poor outcomes," said Dr. Vicki Goodman, vice president, clinical research, Merck Research Laboratories. (merck.com)
  • The KEYTRUDA clinical program seeks to understand the role of KEYTRUDA across cancers and the factors that may predict a patient's likelihood of benefitting from treatment with KEYTRUDA, including exploring several different biomarkers. (merck.com)
  • James de Lemos, MD (UT Southwestern Medical Center, Dallas, TX), a coauthor on the case series with Rosner and colleagues, said the clinical profile of the male patients presenting with myocarditis tends to be quite similar, but all responded well to treatment and there isn't anything at this point to suggest they won't completely recover. (tctmd.com)
  • Some adult patients required treatment for up to 12 weeks in clinical trials. (nih.gov)
  • Jensen CJ, Zadeh B, Wambach JM, Lambers M, Nassenstein K, Bruder O. Association of QRS-T angle and Late Gadolinium Enhancement in patients with a Clinical Suspicion of Myocarditis. (medsci.org)
  • Diagnosis and risk stratification in patients with suspected myocarditis is particularly challenging due to a great spectrum of clinical presentations. (medsci.org)
  • We enrolled 97 consecutive patients that were referred to CMR imaging for a clinical suspicion of myocarditis. (medsci.org)
  • Aim of this study was to investigate a possible association between an abnormal QRS-T-angle on the routine surface ECG and myocardial necrosis as visualized by LGE in patients with a clinical suspicion of myocarditis. (medsci.org)
  • The FDA's acceptance of our application adds to our momentum of advancing new treatment options to address the most challenging cancers facing women," said Dr. Scot Ebbinghaus, vice president, clinical research, Merck Research Laboratories. (businesswire.com)
  • The clinical value of Huangqi injection in the treatment of leucopenia: a meta-analysis of clinical controlled trials. (epnet.com)
  • At this time it is possible that mRNA and adenoviral DNA vaccines could influence key miRNA's in the causal pathway to a primary arrhythmic cardiac death in the absence of clinical myocarditis. (ldsfreedomforum.com)
Cardiac3
  • Cardiac magnetic resonance imaging (MRI) is useful to differentiate between myocarditis and other cardiomyopathies, as well as to target endomyocardial biopsy sites. (medscape.com)
  • Late gadolinium enhancement (LGE) on contrast-enhanced cardiac magnetic resonance (CMR) imaging depicts myocardial necrosis and later replacement fibrosis (scar) in patients with myocarditis with high spatial resolution. (medsci.org)
  • Impella devices are catheter-based heart pumps inserted in the cardiac catheterization lab that can support the heart function until recovery or longer-term treatments can be planned. (choa.org)
Eosinophilic myocarditis1
Infection6
  • Globally, Chagas disease is the leading cause of myocarditis, which results from infection with the protozoan Trypanosoma cruzi. (wikipedia.org)
  • Can COVID-19 infection cause myocarditis? (uvmhealth.org)
  • In people over 12, myocarditis is even more likely to occur after a COVID-19 infection. (rivm.nl)
  • The U.S. Centers for Disease Control and Prevention and Johns Hopkins Medicine also list infection as the most common cause of myocarditis. (politifact.com)
  • Myocarditis may be caused by many disorders, including infection, toxins and drugs that affect the heart, and systemic disorders such as sarcoidosis, but often the cause is unknown. (msdmanuals.com)
  • Treatment of toxocariasis varies, depending on the type of infection. (cdc.gov)
20216
  • Among the next 30 patients (treated March 2020-August 2021), 22 patients with grade ≥ 3 myocarditis received corticosteroids in combination with the selective costimulation modulator abatacept and, in 17 patients, the JAK1 and JAK2 inhibitor ruxolitinib. (nature.com)
  • On June 18, 2021, the CDC's Advisory Committee on Immunization Practices (ACIP) is scheduled to meet and provide an update on vaccine safety, including myocarditis after receipt of one of the mRNA-based vaccines. (tctmd.com)
  • Major Study Reveals Real Myocarditis Risk with mRNA Vaccines-Young Males Most at Risk , TrialSite News, December 9, 2021. (cairco.org)
  • KEYTRUDA was also granted accelerated approval in September 2019, and received full approval in July 2021, in combination with LENVIMA ® (lenvatinib) for the treatment of patients with advanced endometrial carcinoma that is not MSI-H or dMMR, who have disease progression following prior systemic therapy in any setting and are not candidates for curative surgery or radiation. (businesswire.com)
  • During March 2020–January 2021, the period that coincided with the COVID-19 pandemic, the risk for myocarditis was 0.146% among patients diagnosed with COVID-19 during an inpatient or hospital-based outpatient encounter and 0.009% among patients who were not diagnosed with COVID-19. (cdc.gov)
  • with a myocarditis ICD-10-CM code during March 2020–February 2021. (cdc.gov)
Therapeutic2
  • 6 recently published their experience in treating 40 consecutive patients who were admitted to a single cardio-oncology unit (at Hôpital Pitié‐Salpétrière, Paris, France) for ICI-associated myocarditis using various therapeutic strategies. (nature.com)
  • The role of endomyocardial biopsy in establishing the histotype of myocarditis, with inherent therapeutic and prognostic implications. (mdpi.com)
Patients31
  • The objective of this study was to identify the patient, institutional, and utilization characteristics associated with outcome in hospitalized pediatric patients with myocarditis. (nih.gov)
  • A total of 427,615 patients were discharged, and 216 (0.05%) were diagnosed with myocarditis. (nih.gov)
  • Myocarditis patients who died presented with a higher severity of illness and required frequent use of extracorporeal membrane oxygenation and other ICU therapies. (nih.gov)
  • In conclusion, pediatric patients with myocarditis have considerable variability in their presentations and outcomes, use more resources, and die more often than children with other diagnoses. (nih.gov)
  • Bacteria can also result in myocarditis, although it is rare in patients with normal heart function and without a preexisting immunodeficiency. (wikipedia.org)
  • Patients are in need of new treatments that can improve survival outcomes, and these positive results support the potential of KEYTRUDA in combination with chemotherapy as a first-line treatment for patients with the most common form of malignant mesothelioma. (merck.com)
  • There have been few treatment advances for patients with malignant pleural mesothelioma, which can be challenging to treat through surgery and radiation alone," said Dr. Quincy Chu, CCTG's study chair of the IND.227 trial/KEYNOTE-483 trial. (merck.com)
  • The results from the trial have the potential to make a difference for patients with this disease who have had limited treatment options available to them. (merck.com)
  • The trial evaluated KEYTRUDA in combination with chemotherapy for the treatment of patients with unresected advanced malignant pleural mesothelioma. (merck.com)
  • KEYTRUDA is indicated for the treatment of patients with unresectable or metastatic melanoma. (merck.com)
  • The immunotherapy has already been approved for several other NSCLC indications , including as first-line treatment along with pemetrexed and platinum chemotherapy for patients with metastatic nonsquamous NSCLC without EGFR or ALK genomic tumor aberrations. (medscape.com)
  • Two patients experienced fatal myocarditis . (medscape.com)
  • Educate patients about the natural history, progression, and treatment of the disease. (medscape.com)
  • Patients with myocarditis may complain of chest pain, shortness of breath, irregular or fast heartbeat or profound fatigue. (uvmhealth.org)
  • I think it's a very small number compared to the number of patients vaccinated and it's also very small compared with the annual global incidence of myocarditis related to viral illnesses or other etiologies. (tctmd.com)
  • Additionally, Rosner said they were reassured that patients presented quite typically for myocarditis, which allowed them to quickly identify it and start treatment. (tctmd.com)
  • In patients with early Parkinson's disease, selegiline and other drugs in a class called monoamine oxidase type B inhibitors are cheap and effective treatments that reduce disability and the need for levodopa, researchers reported in the British Medical Journal. (digitalnaturopath.com)
  • Balsalazide is aminosalicylate indicated for the treatment of mildly to moderately active ulcerative colitis in patients 5 years of age and older. (nih.gov)
  • To investigate the association of a wide QRS-T angle on the surface ECG and late gadolinium enhancement on contrast-enhanced cardiovascular magnetic (CMR) imaging in patients with clinically suspected myocarditis. (medsci.org)
  • Late gadolinium enhancement (LGE) visualizes myocardial necrosis and fibrosis in patients with biopsy-proven myocarditis. (medsci.org)
  • 78 of 97 patients with suspected myocarditis had LGE on CMR. (medsci.org)
  • A wide QRS-T angle of 90 degrees or more is linked to myocardial fibrosis or necrosis (late gadolinium enhancement) in patients with suspected myocarditis. (medsci.org)
  • We prospectively enrolled 97 consecutive patients that underwent CMR at the Cardiovascular MRI Center, Department of Cardiology and Angiology, Elisabeth Hospital Essen, Germany for clinically suspected myocarditis. (medsci.org)
  • KEYTRUDA monotherapy is already playing a role for the treatment of certain patients with advanced endometrial carcinoma through the tumor-agnostic MSI-H indication which received accelerated approval four years ago. (businesswire.com)
  • KEYTRUDA is approved for the treatment of adult and pediatric patients with unresectable or metastatic MSI-H or dMMR solid tumors that have progressed following prior treatment and who have no satisfactory alternative treatment options. (businesswire.com)
  • Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. (epnet.com)
  • Patients with endocarditis require early diagnosis and long-term antibiotic treatment (at least 18 months) for a successful outcome. (cdc.gov)
  • Compte tenu du nombre croissant d'infections et de décès par le virus de la grippe pandémique (H1N1) 2009 confirmés en laboratoire dans la Région OMS de la Méditerranée orientale, le Bureau régional a convoqué une réunion consultative d'experts impliqués dans la prise en charge clinique de patients infectés par ce virus. (who.int)
  • Among patients with COVID-19, the first myocarditis encounter could have occurred during or after the first COVID-19 health care encounter. (cdc.gov)
  • The risk for myocarditis was defined as the percentage of patients with myocarditis and was calculated among patients with and without COVID-19, overall and by sex (male or female) and age group (<16, 16–24, 25–39, 40–49, 50–64, 65–74, and ≥75 years). (cdc.gov)
  • The percentage of myocarditis patients with a history of COVID-19 was calculated for each age group. (cdc.gov)
Infections2
Incidence4
Disseminated intravascul1
  • Other noted complications included renal failure, myocarditis, pancreatitis and disseminated intravascular coagulation. (aafp.org)
20221
  • In the six years before June 2022, only two similar myocarditis cases were identified in the South Wales region, the WHO said. (politifact.com)
Complications1
Corticosteroids2
  • Management guidelines for ICI-associated myocarditis follow the traditional pathway that is used for other immune-related adverse events (irAEs), with corticosteroids as the initial therapy 4 , 5 . (nature.com)
  • Prolonged treatment with corticosteroids leads to a large number of comorbidities such as diabetes mellitus, hypertension, osteoporosis, and psychiatric disease. (medscape.com)
Etiology2
Infectious2
  • Infectious causes and treatment guidelines are summarized below. (medscape.com)
  • Myocarditis may result from infectious or noninfectious causes. (msdmanuals.com)
Pfizer2
  • Last week, the US Centers for Disease Control and Prevention (CDC) generated headlines when it reported a higher-than-expected number of myocarditis cases among young people who received the Pfizer/BioNTech or Moderna mRNA-based COVID-19 vaccines. (tctmd.com)
  • Japan is particularly raising concerns about the risks of myocarditis in young men injected with Pfizer or Moderna's gene-therapy treatment. (cairco.org)
Outcomes1
  • Involving over 170 children from Sweden in a randomized study, the research showed improvements in children's weight status across different treatment groups, with the best outcomes observed in children whose parents received additional support and follow-up calls. (scitechdaily.com)
Regimens1
  • Treatment regimens should take into account the most recent official treatment guidelines (e.g. those of the WHO) and local information on the prevalence of resistance to antimalarial drugs. (who.int)
Onset1
Immune5
  • Immune-checkpoint-inhibitor-associated myocarditis has a high fatality rate, warranting the development of more-effective treatment strategies. (nature.com)
  • Abatacept/ruxolitinib and screening for concomitant respiratory muscle failure to mitigate fatality of immune-checkpoint inhibitor myocarditis. (nature.com)
  • Immune-checkpoint-inhibitor (ICI)-associated myocarditis is one of the most feared and deadly toxicities to arise from these transformative anticancer therapies. (nature.com)
  • Myocarditis is an inflammatory disease of the heart muscle, both infective and immune in origin. (mdpi.com)
  • Advances in therapy for both viral and immune myocarditis. (mdpi.com)
Chagas1
Chest3
  • If the provider suspects myocarditis based on the exam and chest x-ray, an electrocardiogram may also be done to help make the diagnosis. (medlineplus.gov)
  • Lyme Myocarditis Presenting as Chest Pain in an Adolescent Girl. (canlyme.com)
  • In mild cases of myocarditis, common s ymptoms include chest pain and shortness of breath . (sott.net)
Cohort1
  • A patient-level cohort was created to assess the association between COVID-19 and myocarditis. (cdc.gov)
Chemotherapy1
  • Cardiotoxicity: A muscle injury that may result from certain medications and treatments, such as chemotherapy and radiation. (choa.org)
Adjuvant Treatment1
  • The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. (epnet.com)
Uncommon1
MRNA vaccines2
  • Myocarditis can be a rare side-effect of the Covid-19 mRNA vaccines. (wikipedia.org)
  • There were roughly 19.7 million doses of the mRNA vaccines administered and 417 cases of myocarditis or pericarditis found in the Ontario registry. (acsh.org)
Immunosuppressive therapy1
  • Three previously published cases with less impressive responses to treatment including muromonab-CD3 and a critical review of the published data on immunosuppressive therapy are included in this report. (nih.gov)
Myocardial2
  • Treatment of acute myocardial infarction 18. (muni.cz)
  • Details for: Treatment of reversible myocardial ischemia-angina pectoris. (who.int)