• Both DNA samples were subjected to unbiased to detect bacterial pathogens, we used it on DNA from a high-throughput DNA sequencing with a GS20 sequencer patient's feces during and after diarrheal illness. (cdc.gov)
  • Overall my research aims to elucidate how Gram-negative bacterial pathogens are able to successfully cause disease. (dundee.ac.uk)
  • All together, these areas contribute towards a better understanding of how Gram-negative bacterial pathogens interact with each other and with the host organism to proliferate and cause disease. (dundee.ac.uk)
  • We study a number of Gram-negative bacterial pathogens, mostly members of the Enterobacteriaceae, including the human pathogens Serratia marcescens , E. coli and Klebsiella pneumoniae , and the plant pathogens Erwinia spp. (dundee.ac.uk)
  • My laboratory is interested in understanding, treating, and preventing diarrheal disease caused by bacterial pathogens. (k-state.edu)
  • The goal of this study was to define how bacterial pathogens exploit eukaryotic secretory pathways. (k-state.edu)
  • Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens. (k-state.edu)
  • important virulence determinants of several bacterial pathogens, including and varieties3,4. (phytid.org)
  • While many two-component systems control basic cellular processes such as motility, nutrient uptake and cell division, bacterial pathogens use two-component systems to control virulence. (mechanobio.info)
  • SPase I has long been thought to be essential for viability in multiple bacterial pathogens. (microbialcell.com)
  • The Tat system is involved in a wide range of fundamental cellular processes in bacteria and is essential for the virulence of bacterial pathogens. (ox.ac.uk)
  • Bacterial effectors are proteins secreted by pathogenic bacteria into the cells of their host, usually using a type 3 secretion system (TTSS/T3SS), a type 4 secretion system (TFSS/T4SS) or a Type VI secretion system (T6SS). (wikipedia.org)
  • Once a pathogen genome has been sequenced, effectors can be predicted based on protein sequence similarity, but such predictions are not always precise. (wikipedia.org)
  • Finally, even within the same bacterial species, different strains often have different repertoires of effectors. (wikipedia.org)
  • Similarly, the Shigella effectors IpgD and OspG (a homolog of NleH) block apoptosis, the former by phosphorylating and stabilizing the double minute 2 protein (MDM2) which in turn leads to a block of NF-kB-induced apoptosis. (wikipedia.org)
  • The goal of this study was to determine how bacterial effectors inhibit type I interferon production. (k-state.edu)
  • We discovered that the mutation of order Brequinar effectors resulted in increased take a flight success but, paradoxically, increased bacterial survival also. (thetechnoant.info)
  • These effectors are involved in producing surface structures for adhesion, bacterial motility, manipulation of host functions, modulation of host defense responses, and other functions involved in facilitating survival of the pathogen. (bvsalud.org)
  • consists of one group of TTSS program, which translocates four bacterial effectors into sponsor cells to facilitate creating and disseminating severe attacks. (phytid.org)
  • Once translocated, both effectors perturb the sponsor Rac signalling program and trigger cell apoptosis/loss of life6,7,9,10. (phytid.org)
  • While some effector proteins specifically target bacterial or eukaryotic cells, others can target both types of cells (trans-kingdom effectors). (frontiersin.org)
  • Of note, the genes encoding these effectors and immunity proteins are widely distributed in Salmonella genomes, suggesting a relevant role in interbacterial competition and virulence. (frontiersin.org)
  • Oh C, Li L, Verma A, Reuven AD, Miao EA, Bliska JB, Aachoui Y. Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins. (uams.edu)
  • In addition, heterologous antisera directed against components of the Toc/Tic translocons and binding of a labeled precursor protein were used to discriminate between inner and outer envelope membranes. (biomedcentral.com)
  • Indeed, a dual localization of SecY protein in both cytoplasmic and thylakoid membranes from the cyanobacterium Synechococcus PCC7942 was reported [ 4 ]. (biomedcentral.com)
  • 4) Protein translocation across membranes. (nottingham.ac.uk)
  • has two type III secretory apparatuses (TTSAs) that translocate Gpr124 effector proteins across both bacterial and host membranes into the host cell cytoplasm. (thetechnoant.info)
  • These proteins are targeted to the mitochondria, translocated through the mitochondrial membranes, and sorted to the different mitochondrial subcompartments. (nih.gov)
  • Transport of proteins across membranes is a fundamental process, achieved in every cell by the 'Sec' translocon. (elifesciences.org)
  • The encapsulation and compartmentalisation of cells has necessitated the evolution of machineries that conduct proteins across membranes, including for protein secretion and organellar import. (elifesciences.org)
  • This course will introduce how proteins are translocated across membranes and secreted outside of bacterial cells or even transported into the hose cells. (ntu.edu.tw)
  • Theseresults provide an experimental avenue for real-time monitoring of bacterial T3 effector translocation into plant cells with apathological consequence. (ias.ac.in)
  • The Sec translocase which provides a major pathway of protein translocation from the cytosol across the cytoplasmic membrane in bacteria is best investigated in Escherichia coli . (biomedcentral.com)
  • This SecYEG complex and the hydrophilic protein SecA, which acts as the translocation ATPase, are the primary components of the Sec translocation machinery. (biomedcentral.com)
  • The twin arginine translocation (TAT) system ferries folded proteins across the bacterial membrane. (aston.ac.uk)
  • Electron cryoEM structures of mitochondrial, chloroplast, and bacterial ATP synthases have revealed the architecture of the FO region, helping to explain the mechanisms of proton translocation, dimerization of the enzyme in mitochondria, and cristae formation. (tcdb.org)
  • Protein components in the matrix partake in energetically driving translocation in a reaction that depends on the membrane potential and matrix-ATP. (nih.gov)
  • Molecular chaperones in the matrix exert multiple functions in translocation, sorting, folding, and assembly of newly imported proteins. (nih.gov)
  • In prokaryotes, SecYEG associates with the motor ATPase SecA to carry out translocation for pre-protein secretion. (elifesciences.org)
  • This paper explores how the protein folding process per se may be exploited to drive protein translocation. (elifesciences.org)
  • The protein must then fold during or after the translocation process. (elifesciences.org)
  • Pneumococci then actively translocate across undamaged endothelial layers [8] by means of specific receptor binding and translocation. (biobender.com)
  • More importantly, it is difficult to prove experimentally that a predicted effector is actually secreted into a host cell because the amount of each effector protein is tiny. (wikipedia.org)
  • We show that the bacterial effector protein SseI (also called SrfH), which is translocated into host cells by the Salmonella Pathogenicity Island 2 (SPI2) type III secretion system (T3SS), is required for Salmonella typhimurium to maintain a long-term chronic systemic infection in mice. (pasteur.fr)
  • Modulation of host cytoskeleton function by the enteropathogenic Escherichia coli and Citrobacter rodentium effector protein EspG. (k-state.edu)
  • 2003). Within this ongoing function we thought we would research due to its well-characterized secreted effector protein. (thetechnoant.info)
  • The Tat protein export system translocates folded proteins across the bacterial cytoplasmic membrane and the plant thylakoid membrane. (markwallace.org)
  • The Tat system is a recently discovered protein export pathway that serves to translocate folded proteins, often containing redox cofactors, across the bacterial cytoplasmic membrane. (ox.ac.uk)
  • Phagocytes recognize bacteria directly [e.g., through the so-called scavenger receptor A which recognizes bacterial lipopolysaccharide (LPS) ] or indirectly through antibodies (IgG) and complement proteins (C3bi) which coat the bacteria and are recognized by the Fcγ receptors and integrinαmβ2 (complement receptor 3). (wikipedia.org)
  • Our largest research area is the Type VI secretion system (T6SS) , which is widespread in Gram-negative bacteria and is a complex, dynamic nanomachine which 'fires' toxic effector proteins into target cells. (dundee.ac.uk)
  • Bacteriocins are protein antibiotics produced by strains of bacteria that are active against related bacteria. (nottingham.ac.uk)
  • Bacterial swarming is an important mechanism for flagellated bacteria to effectively cover large distances on soft surfaces, such as tissues. (aps.org)
  • In GRAM NEGATIVE BACTERIA, multiprotein complexes that function to translocate pathogen protein effector molecules across the bacterial cell envelope, often directly into the host. (bvsalud.org)
  • Our findings highlight alternative strategies for handling and export of amyloid protein sequences.Gram-negative bacteria assemble biofilms from amyloid fibres, which translocate across the outer membrane as unfolded amyloid precursors through a secretion system. (ox.ac.uk)
  • Two-component regulatory systems (TCRS) are important mediators of signal transduction that enable bacteria to detect physical and/or chemical changes and then relay this signal through the cytoplasm to the bacterial nucleoid, where modulation of gene expression occurs. (mechanobio.info)
  • In which the spacing between these epithelial cells increases and allows bacterial proteins or bacterial components like lipopolysaccharide, saccharides, or even whole bacteria themselves to translocate into our bloodstream. (rheumatoidsolutions.com)
  • The Type VI Secretion System (T6SS) is a multiprotein device that has emerged as an important fitness and virulence factor for many Gram-negative bacteria through the injection of effector proteins into prokaryotic or eukaryotic cells via a contractile mechanism. (frontiersin.org)
  • Secretion of proteins into the extracellular environment is crucial for the normal physiology and virulence of pathogenic bacteria. (microbialcell.com)
  • In bacteria, this comprises SecY, SecE and usually SecG, with the protein-conducting pore running through the centre of SecY. (elifesciences.org)
  • The CusB protein is part of the CusCBA periplasmic Cu(I) efflux system in Gram-negative bacteria, and it was recently reported to play a key role in the functioning of the whole CusCBA system, in which conformational changes as well as the assembly/disassembly process control the opening of the transporter. (biorxiv.org)
  • Salmonella typhimurium bacteria cause diarrhea using a novel mechanism: the bacterial protein flagellin finds its way through the first layer of the intestinal cells lining the gut, where the body's response mechanisms kicks in to try and rid the foreigner. (science-bbs.com)
  • The finding, due to be published early next year and reported here today, is the first report of any bacteria actively translocating a protein across an entire cell layer. (science-bbs.com)
  • Many bacteria, including the ubiquitous Escherichia coli and many types of 'good' bacteria, produce and secrete flagellin, a protein that makes up bacterial flagella. (science-bbs.com)
  • It has been observed in some children that bacteria can translocate directly from the nasopharynx into the CNS via olfactory neurones [12]. (biobender.com)
  • Effector proteins may have many different activities, but usually help the pathogen to invade host tissue, suppress its immune system, or otherwise help the pathogen to survive. (wikipedia.org)
  • Gram negative microbes are also suspected to deploy bacterial outer membrane vesicles to translocate effector proteins and virulence factors via a membrane vesicle trafficking secretory pathway, in order to modify their environment or attack/invade target cells, for example, at the host-pathogen interface. (wikipedia.org)
  • For many of our studies we use the potent anti-bacterial T6SS of the opportunistic pathogen Serratia marcescens as a model system. (dundee.ac.uk)
  • The helical-rod shape of Helicobacter pylori, a human stomach pathogen, is important for its pathogenesis and is an ideal model system for studying complex bacterial cell shapes. (aps.org)
  • A prominent example is the gram-negative pathogen Salmonella Typhimurium , which is a frequent cause of bacterial gastroenteritis. (mechanobio.info)
  • Protein secretion systems are molecular machines used by bacterial cells to translocate specific sets of proteins out of the bacterial cell, either to the extracellular milieu or directly into target cells (eukaryotic or prokaryotic. (dundee.ac.uk)
  • Secretion systems, and the diverse proteins that they secrete, represent key virulence factors against eukaryotic host organisms. (dundee.ac.uk)
  • It is increasingly becoming recognised that protein secretion systems can also be important mediators of competition between bacterial cells, with such systems delivering anti-bacterial toxins. (dundee.ac.uk)
  • We are interested in the molecular mechanisms and regulation of the T6SS machinery, but also in the identification and characterisation of new anti-bacterial toxins secreted by the system. (dundee.ac.uk)
  • This episode: Bacterial toxins could be modified to deliver life-saving proteins into neurons! (bacteriofiles.com)
  • I will conclude with a brief note on how mechanically-stimulated regulatory events influence a host of important processes such as bacterial competence, which regulates the uptake of extracellular DNA. (aps.org)
  • Second, the extracellular location of the enzymatic pocket makes this target relatively accessible as it obviates the requirement of the inhibitor to traverse the bacterial membrane. (microbialcell.com)
  • In the poster section, Joanna Shisler (University of Illinois at Urbana-Champaign [UIUC], Urbana) reported that the modified virus, Ankara, activates nuclear factor κB through the mitogen-activated protein kinase, extracellular signal–regulated kinase (MEK)/extracellular signal–regulated kinase (ERK) pathway, possibly facilitating the host immune response. (cdc.gov)
  • The envelope translocase can be envisaged as a prokaryotic feature missing in higher plant chloroplasts but retained in cyanelles, likely for protein transport to the periplasm. (biomedcentral.com)
  • Prokaryotic importers require additional extracytoplasmic binding proteins (one or more per systems) for function. (embl.de)
  • Structural evidence that colicin A protein binds to a novel binding site of TolA protein in Escherichia coli periplasm Journal of Biological Chemistry. (nottingham.ac.uk)
  • FapF forms a trimer of gated β-barrel channels in which opening is regulated by a helical plug connected to an extended coil-coiled platform spanning the bacterial periplasm. (ox.ac.uk)
  • TPS systems are TpsA for translocated proteins to the bacterial surface and TpsB for the transporter proteins. (biomedcentral.com)
  • The spermidine transporter of consists of five proteins, i.e., the periplasmic substrate-binding protein SpuD and SpuE, the ATPase SpuF, as well as the internal membrane permeases SpuG and SpuH that constitute the cross-membrane route18. (phytid.org)
  • A putative bacterial ABC transporter circumvents the essentiality of signal peptidase. (microbialcell.com)
  • This transporter apparently compensates for SpsB's essential function by mediating alternative cleavage of a subset of proteins at a site distinct from the SpsB-cleavage site, leading to SpsB-independent secretion. (microbialcell.com)
  • Over-expression of the ABC transporter overcomes the S. aureus lethality caused by either pharmacologic inhibition or genetic ablation of SpsB, and is associated with secretion of alternatively cleaved proteins [3] [5] (see Figure 2 for a model). (microbialcell.com)
  • GSD type Id is deficiency in a transporter that translocates free glucose molecules from microsomes into the cytosol. (medscape.com)
  • Colicins are protein antibiotics produced by strains of Escherichia coli to kill non-producing strains of the same organims presumably as a method of competitive inhibition. (nottingham.ac.uk)
  • Escherichia coli strains blocked in Tat-dependent protein export exhibit pleiotropic defects in the cell envelope. (ox.ac.uk)
  • instead, both DNA samples, 20% of the total sequences showed they amplify single isolated DNA molecules and analyze the best matches for the currently reported bacterial DNA them with massively parallel processing. (cdc.gov)
  • These biological nanopores have been designed to protect the interior of the bacterial cell from leakage of toxic compounds while selectively allowing the entry of the molecules needed for cell growth and function. (ibecbarcelona.eu)
  • Here we present a theoretical framework for analysing the filter of general porins in relation to translocating molecules with the aid of enhanced molecular simulations quantitatively. (ibecbarcelona.eu)
  • Proteins are directed into this system by the TAT signal peptide present at the amino terminus of the precursor protein, which contains the twin arginine residues that give the system its name. (aston.ac.uk)
  • The TatC component of the twin-arginine protein translocase functions as an obligate oligomer. (markwallace.org)
  • Type I signal peptidase (SPase I) mediates the final step of bacterial secretion, by cleaving proteins at their signal peptide once they are translocated by the Sec or twin-arginine (Tat) translocon. (microbialcell.com)
  • We sought to determine if there was antibody deposition in SAH livers and whether antibodies extracted from SAH livers were cross-reactive against both bacterial antigens and human proteins. (elifesciences.org)
  • antibody responses to polysaccharide antigens are decreased and antibody responses to protein antigens are slightly reduced. (medscape.com)
  • We directly detected the causative pathogenic bacterial species in both samples belonged to the phylum microbe in a clinical human sample (diarrheic feces) by Bacteroidetes, the normal fl ora of the human intestine. (cdc.gov)
  • More broadly, I have had a long-standing interest in inter-bacterial interactions, including past work on quorum sensing in pathogenic Enterobacteriaceae. (dundee.ac.uk)
  • Unraveling the mechanism of SpsB-independent secretion may provide an interesting twist to the paradigm of bacterial secretion. (microbialcell.com)
  • The mechanism of Tat transport is radically different from that employed by other protein transporters, enabling it to translocate folded proteins without compromising the ion permeability barrier of the membrane. (ox.ac.uk)
  • The control of nuclear localization via phosphorylation and dephosphorylation serves as the primary regulatory mechanism for MiT family proteins, and several kinases and phosphatases have been identified to directly determine the transcriptional activities of MiT proteins. (molcells.org)
  • These nanomachines have crucial roles in pathogenesis, motility, and antibiotic resistance, and are amongst the most mechanistically interesting proteins in the cell. (ox.ac.uk)
  • The Type IX secretion system (T9SS) which is involved in severe dental disease and in bacterial gliding motility. (ox.ac.uk)
  • NDRs are functionally important in proteins throughout the three kingdoms of life as well as being implicated in cancer, amyloid diseases and bacterial pathogenesis. (nottingham.ac.uk)
  • Functionally, BNIP3L-mediated mitophagy appears to be advantageous for bacterial exit from the host cell as BNIP3L depletion drastically reduces the number of reinfection events. (bvsalud.org)
  • The secretion of bacterial functional amyloid requires a bespoke outer-membrane protein channel through which unfolded amyloid substrates are translocated. (ox.ac.uk)
  • This multi-component system exports proteins through a huge pore in the outer membrane using the energy of the inner membrane proton electrochemical gradient. (ox.ac.uk)
  • More commonly, however, the target is rival bacterial cells, making the T6SS a key player in inter-bacterial competition and competitive fitness, and therefore an indirect virulence factor. (dundee.ac.uk)
  • The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function. (k-state.edu)
  • EspG functions as a Rab GTPase-activating protein (Rab-GAP), trapping Rab-GTPases in their inactive GDP bound form, and reducing ER-Golgi transport (of IL-8 and other proteins). (wikipedia.org)
  • The microphthalmia-associated transcription factor family (MiT family) proteins are evolutionarily conserved transcription factors that perform many essential biological functions. (molcells.org)
  • The best studied functions of MiT proteins include lysosome biogenesis and autophagy induction. (molcells.org)
  • These subtypes are clinically indistinguishable from one another, except for the fact that patients with GSD type Ib have altered neutrophil functions predisposing them to gram-positive bacterial infections. (medscape.com)
  • While showing several structural and functional features typical for bacterial cellulose active LPMOs, Sc LPMO10D is only active on chitin. (nature.com)
  • The majority of this work uses machine learning to predict protein structural and functional features. (giwebb.com)
  • However, most current approaches used for functional annotation simply focus on the use of protein-level information but ignore inter-relationships among annotations.Here, we established PFresGO, an attention-based deep-learning approach that incorporates hierarchical structures in Gene Ontology (GO) graphs and advances in natural language processing algorithms for the functional annotation of proteins. (giwebb.com)
  • showing the cavities through the channel, with the protein in grey surface, the pre-protein pore constrictions in red (SecY) or purple (SecA) mesh, and the SecY plug in red helix. (elifesciences.org)
  • Phosphate-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • oryzae are translocated into rice cells to inducevirulence and avirulence on susceptible- and resistant-rice varieties Nipponbare and IRBB10, respectively. (ias.ac.in)
  • Our computational imaging framework allows us to extract 3D shapes of individual bacterial cells from fluorescence microscopy images. (aps.org)
  • SseI inhibits normal cell migration of primary macrophages and dendritic cells (DC) in vitro, and such inhibition requires the host factor IQ motif containing GTPase activating protein 1 (IQGAP1), an important regulator of cell migration. (pasteur.fr)
  • Cells secrete a large number of proteins to communicate with their surroundings. (cipsm.de)
  • The team concluded that the bacterial protein flagellin induces nausea by traveling all the way through the first layer of endothelial cells in the gut to enter the body's inner domain. (science-bbs.com)
  • Proteins such as pneumolysin can Veliparib result in apoptosis on entering cells by damage of the mitochondria. (biobender.com)
  • Mn, serum Mn, urine Mn, Centromere-positive micronuclei in periphery blood lymphocytes, DNA protein-crosslinks in peripheral white blood cells, oxidative stress as urinary 8OHdG, and long-term oxidative damage measured as erythrocytic superoxide dismutase (SOD) activity (measure of systemic oxidative stress) and serum malondialdehyde (MDA) (product of lipid peroxidation and reflect tissue injuries). (who.int)
  • The presence of cross-reacting anti-bacterial IgG and IgA autoantibodies in the liver may participate in the pathogenesis of SAH. (elifesciences.org)
  • In certain bacterial transporters, these regions are found on different polypeptides. (embl.de)
  • This ability to exploit structure within a pre-protein is an unexplored area of protein transport, which may apply to other protein transporters, such as those of the endoplasmic reticulum and mitochondria. (elifesciences.org)
  • Additionally, bacterial virulence proteins utilize many molecular mechanisms that are also conserved among viruses of importance to biosecurity. (k-state.edu)
  • My research team has discovered several mechanisms by which bacterial proteins subvert the host innate immune system to promote bacterial colonization and transmission. (k-state.edu)
  • 2016). Here, we show that ATP enhances this process by modulating secondary structure formation within the translocating protein. (elifesciences.org)
  • Our model of RapA in complex with ATP and double-stranded DNA (dsDNA) suggests that RapA may bind to and translocate on dsDNA. (proteopedia.org)
  • Proteins that bind to and are involved in the metabolism of phosphate ions. (uams.edu)
  • The eukaryotic proteins are more complicated than the bacterial enzyme complexes. (tcdb.org)
  • The variant TatC proteins retained the ability to interact with TatB and with a Tat substrate but were unable to support the in vivo assembly of TatA complexes. (markwallace.org)
  • Blue-native PAGE analysis showed that the variant TatC proteins produced smaller TatBC complexes than the wild type TatC protein. (markwallace.org)
  • Mitochondria import many hundreds of different proteins that are encoded by nuclear genes. (nih.gov)
  • He also showed that double-stranded (ds)RNA- and ZDNA binding proteins had a role in poxvirus pathogenesis. (cdc.gov)
  • The systems mediate a complicated membrane transport procedure that directly provides bacterial effector proteins from bacterial cytoplasm into eukaryotic cell cytoplasm to allow bacterial infections. (phytid.org)
  • Both proteins mediate protein-protein and protein-RNA interactions for cooperative RNA-binding during spliceosome assembly. (cipsm.de)
  • Our findings highlight alternative strategies for handling and export of amyloid protein sequences. (diamond.ac.uk)
  • Our work is grounded in protein biochemistry and bacterial cell biology to which we add a full range of cutting edge molecular techniques. (ox.ac.uk)
  • Hereditary inactivation of TTSS considerably attenuated the virulence of stress PAO1, the genes necessary for the TTSS equipment are clustered inside a 12-kb area from the chromosome, where in fact the and genes mainly encode the TTSS structural parts, as well as the and genes encode the regulatory protein. (phytid.org)
  • There are currently only two computational methods for the prediction of TAT translocated proteins from sequence. (aston.ac.uk)
  • RapA, as abundant as sigma70 in the cell, is an RNA polymerase (RNAP)-associated Swi2/Snf2 protein with ATPase activity. (proteopedia.org)
  • A combination of molecular simulation with hydrogendeuterium-exchange mass spectrometry and electron paramagnetic resonance spectroscopy reveal an asymmetry across the membrane: ATP-induced conformational changes in the cytosolic cavity promote unfolded pre-protein structure, while the exterior cavity favours its formation. (elifesciences.org)
  • To date, only a few predictors are available for identifying general bacterial promoters with limited predictive performance.In this study, we developed TIMER, a Siamese neural network-based approach for identifying both general and species-specific bacterial promoters. (giwebb.com)
  • Specifically, TIMER uses DNA sequences as the input and employs three Siamese neural networks with the attention layers to train and optimize the models for a total of 13 species-specific and general bacterial promoters. (giwebb.com)
  • A family of Type VI secretion system effector proteins that form ion-selective pores. (dundee.ac.uk)
  • Bacterial F-type ATPases pump 3-4 H + and/or Na + (depending on the system) out of the cell per ATP hydrolyzed. (tcdb.org)
  • The Tat system in Escherichia coli is comprised of TatA, TatB and TatC proteins. (markwallace.org)
  • The typical bacterial scenario seemed to be a two-component sHsps system of two homologous sHsps, such as the Escherichia coli sHsps IbpA and IbpB. (cipsm.de)