Mice, TransgenicCell ProliferationPlants, Genetically ModifiedTransgenesAnimals, Genetically ModifiedCells, CulturedTobaccoCell LineMice, Inbred C57BLGreen Fluorescent ProteinsCell DivisionSignal TransductionApoptosisCell Line, TumorCell DifferentiationCell CycleRNA, MessengerBromodeoxyuridineImmunohistochemistryBlotting, WesternGene ExpressionCell SurvivalCell MovementGene Expression RegulationReverse Transcriptase Polymerase Chain ReactionLymphocyte ActivationRats, TransgenicDisease Models, AnimalPhosphorylationMice, KnockoutProliferating Cell Nuclear AntigenMolecular Sequence DataGene Expression Regulation, NeoplasticTumor Cells, CulturedDown-RegulationKi-67 AntigenRNA, Small InterferingFlow CytometryT-LymphocytesTranscription FactorsTransfectionEpithelial CellsBase SequencePhenotypeCell Growth ProcessesTime FactorsUp-RegulationPromoter Regions, GeneticStem CellsDose-Response Relationship, DrugMice, Inbred BALB CGene Expression Regulation, DevelopmentalCyclin D1RNA InterferenceMutationHyperplasiaCell CountFibroblastsMice, NudeCell Transformation, NeoplasticDNADNA-Binding ProteinsProto-Oncogene Proteins c-aktThymidineMuscle, Smooth, VascularCyclin-Dependent Kinase Inhibitor p27Enzyme ActivationProto-Oncogene ProteinsProto-Oncogene Proteins c-mycRats, Sprague-DawleyCell Cycle ProteinsEnzyme InhibitorsDNA PrimersRecombinant ProteinsNuclear ProteinsGrowth InhibitorsProtein-Serine-Threonine KinasesGene Knockdown TechniquesTranscription, GeneticAmino Acid SequenceExtracellular Signal-Regulated MAP KinasesMyocytes, Smooth MuscleModels, BiologicalCyclin-Dependent Kinase Inhibitor p21Gene Expression ProfilingRecombinant Fusion ProteinsTrans-ActivatorsAntineoplastic AgentsMitogensMAP Kinase Signaling SystemTransforming Growth Factor betaB-LymphocytesIn Situ HybridizationLiverMitogen-Activated Protein Kinase 3Breast NeoplasmsIn Situ Nick-End LabelingTumor Suppressor Protein p53G1 PhaseNeovascularization, Pathologic