• pathological
  • However, under pathological conditions inducing mucous cell metaplasia, an increased goblet cell population in the mucosa produces excessive mucins, while the loss of ciliated cells in the mucosa results in the dysfunction of the mucociliary transport system, leading to subsequent problems such as fluid accumulation and repeated infections. (hindawi.com)
  • When cells are faced with physiological or pathological stresses, they respond by adapting in any of several ways, one of which is metaplasia. (wikipedia.org)
  • clinical
  • Atoh1 and SPDEF could be the therapeutic targets for otitis media associated with mucous cell metaplasia which is frequently considered "intractable" in the clinical settings. (hindawi.com)
  • cells
  • The presence of endocervical cells is one measure of the adequacy of a Pap smear, indicating that the transformation zone has been sampled. (powershow.com)
  • The following table lists some common tissues susceptible to metaplasia, and the stimuli that can cause the change: Epigenetics Induced stem cells List of biological development disorders Reprogramming Transdifferentiation The AMA Home Medical Encyclopedia, Random House, p. 683 Robbins and Cotran - Pathologic Basis of Disease, 7th Edition, Saunders, p. 10 Prof. Dr. Clark S., Australian Cancer institute, premalignant conditions. (wikipedia.org)
  • condition
  • Metaplastic change is often viewed as a premalignant condition that requires immediate intervention, either surgical or medical, because metaplasia is associated with cancer. (wikipedia.org)
  • In this condition, cartilaginous metaplasia takes place within the synovial membrane of the joint. (wikipedia.org)
  • While stomatitis nicotina that is caused by heat is not a premaligant condition (i.e. it does not carry an increased risk of transformation to oral cancer), the condition that is caused by reverse smoking is premalignant. (wikipedia.org)
  • areas
  • Histopathology of the lesion shows large areas of mature fibrous stroma undergoing hyaline cartilage metaplasia resulting in conspicuous lobules or gradual transformation into chondroid foci. (wikipedia.org)
  • cell
  • On the other hand, SAM-pointed domain-containing Ets transcription factor (SPDEF), a member of the "Ets" transcription factor family, has been reported to trigger the mucous cell metaplasia of pulmonary infectious diseases or athsma. (hindawi.com)