Arthritis, RheumatoidArthritisGenotypeDisease SusceptibilityGenetic Predisposition to DiseaseArthritis, ExperimentalArthritis, InfectiousSynovial MembranePolymorphism, Single NucleotideArthritis, JuvenileAntirheumatic AgentsAllelesPolymorphism, GeneticSynovial FluidRheumatoid FactorArthritis, PsoriaticQuantitative Trait, HeritableHaplotypesGene FrequencyJointsGenetic VariationGeneticsCase-Control StudiesPhenotypeGenome-Wide Association StudyArthritis, ReactiveHLA-DRB1 ChainsChromosome MappingGenetic MarkersSynovitisGenetic LinkageLinkage DisequilibriumOsteoarthritisHLA-DR AntigensGenetics, PopulationMethotrexateAutoantibodiesSeverity of Illness IndexModels, GeneticBlood SedimentationAutoimmune DiseasesMice, Inbred DBATumor Necrosis Factor-alphaLupus Erythematosus, SystemicEpistasis, GeneticMolecular Sequence DataSulfasalazineRheumatoid NoduleImmunoglobulin GMetacarpophalangeal JointMutationPolymerase Chain ReactionGenome, HumanCrosses, GeneticGold Sodium ThiomalatePeptides, CyclicHLA-DQ AntigensMicrobial Sensitivity TestsGenetic Association StudiesArthrographySpondylitis, AnkylosingRheumatologyGenetic LociRisk FactorsMicrosatellite RepeatsSequence Analysis, DNARheumatic DiseasesWrist JointCohort StudiesHLA-DR4 AntigenHLA-DQ beta-ChainsDisease Models, AnimalTreatment OutcomeCrohn DiseaseAntibodies, MonoclonalQuantitative Trait LociHLA-DR3 AntigenImmunity, InnateGenetic TestingHLA AntigensFinger JointPlant DiseasesPedigreeNod2 Signaling Adaptor ProteinEuropean Continental Ancestry GroupBiological MarkersGenetic Diseases, InbornBase SequenceCollagen Type IIAsian Continental Ancestry GroupMice, Inbred C57BLTime FactorsSpecies SpecificityCytokinesCitrullineAnti-Bacterial AgentsCells, CulturedPolymorphism, Restriction Fragment LengthComplement C4aReceptors, Tumor Necrosis Factor