Toxicity rats to methoxychlor. Medical search. Frequent questions

Extrapolating human effect thresholds from animal toxicity data for the derivation of immediately dangerous to life and health values. (cdc.gov)

Actual damage to bee populations is a function of toxicity and exposure of the compound, in combination with the mode of application. (wikipedia.org)
Insecticide toxicity is generally measured using acute contact toxicity values LD50 - the exposure level that causes 50% of the population exposed to die. (wikipedia.org)
Acute toxicity may depend on the mode of exposure, for instance, many pesticides cause toxic effects by contact while neonicotinoids are more toxic when consumed orally. (wikipedia.org)
The effects of in vivo exposure of methoxychlor to immature rats on serum progesterone and estradiol levels and the ex vivo formation of progesterone by theca-interstitial cells. (cdc.gov)
170) 1.Hazardous substances - toxicity 2.Environmental exposure 3.Guidelines I.Series ISBN 92 4 157170 5 (NLM Classification: WA 465) ISSN 0250-863X The World Health Organization welcomes requests for permission to reproduce or translate its publications, in part or in full. (inchem.org)
Adult D. magna were exposed to either 1) virgin 10-20µm polyethylene pellets, 2) methoxychlor, or 3) various combinations of the same pellet and methoxychlor concentrations for 48 hours or 7 days using a static exposure method. (umwrcd.net)

The primary purpose of this chapter is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective on the toxicology of methoxychlor. (cdc.gov)

This is because several of the contaminants in technical grade methoxychlor are directly estrogenic (Kupfer and Bulger 1987b), whereas pure methoxychlor is proestrogenic and requires metabolic activation before exhibiting estrogenic activity (Bulger et al. (cdc.gov)
Some of the estrogenic contaminants of technical grade methoxychlor are the same as those formed by metabolism in vivo (Bulger et al. (cdc.gov)

Methods for UV filter analysis followed the principles of European standardized methods for pesticide residue analysis (EN 15289). (researchgate.net)
This study assessed the potential synergistic or antagonistic effects of polyethylene nanoparticles and the organochlorine pesticide methoxychlor on the viability and mobility of Daphnia magna. (umwrcd.net)

Sanchez-Ramos JFacca ABasit ASong S Toxicity of dieldrin for dopaminergic neurons in mesencephalic cultures. (jamanetwork.com)
Pregnenolone protects neurons against cell toxicity and toxin-induced cell death. (genemedics.com)

1980. Toxicity and bioaccumulation of endrin and methoxychlor in aquatic invertebrates and fish. (cdc.gov)
Thus far, few studies have examined the ability of NPs to influence the toxicity of organochlorine pesticides in aquatic invertebrates. (umwrcd.net)
Few laboratory studies have examined the relationship between acidified rainfall and the release of trace metals from coal ash and the impacts of such rainfall on the toxicity of coal ash leachates on aquatic invertebrates. (umwrcd.net)
This study will provide important information regarding the potential impacts of acidified rainfall on the mobilization of trace contaminants and toxicity of coal ash leachates on aquatic invertebrates. (umwrcd.net)

The acute toxicity of pesticides on bees, which could be by contact or ingestion, is usually quantified by LD50. (wikipedia.org)
Acute toxicity of pesticides causes a range of effects on bees, which can include agitation, vomiting, wing paralysis, arching of the abdomen similar to sting reflex, and uncoordinated movement. (wikipedia.org)

2000. The effect of raloxifene on the uterine weight response in immature mice exposed to 17- estradiol, 1,1,1-trichloro-2,2- bis ( p -chlorophenyl)ethane, and methoxychlor. (cdc.gov)
1999. Methoxychlor given in the pre- implantation period blocks sexual arousal in male mice. (cdc.gov)
In mice and rats, pregnenolone administration enhances learning and memory. (genemedics.com)
In mice and rats, pregnenolone supplementation improves performance in various mazes. (genemedics.com)

At that time, the Joint Meeting did not recommend an acceptable daily intake because of the concern that the technical product might contain hexachlorocyclopentadiene since no information was available on the composition of technical chlordane and the nature and toxicity of terminal residues. (inchem.org)
1963). Both technical chlordane and one of its pure isomers (gamma-chlordane) have been shown to have stimulating effects on rat liver microsomes for the metabolism of certain drugs (Burns et al. (inchem.org)
1964). In vitro metabolism by hepatic microsomal enzymes from rats treated 8 days previously with single i.p. doses of 10 or 100 mg/kg of chlordane in corn oil was increased for the 3 drugs reported (hexobarbital, aminopyrine and chlorpromazine). (inchem.org)

1953). It is stored in the adipose tissue of rats, sheep, goats, and cows and accumulates in the milk. (inchem.org)

Please refer to Chapter 4 for more detailed information on the composition of methoxychlor. (cdc.gov)

The acute toxicity, although more lethal, is less common than sub-lethal toxicity or cumulative effects. (wikipedia.org)
While this project is currently ongoing, we expect to find a significant difference in mobility parameters and mortality rates when exposed to the combination of polyethylene pellets and methoxychlor compared to the effects from each contaminant alone. (umwrcd.net)

1974. Pesticidal chemicals affecting some energy-linked functions of rat liver mitochondria in vitro . (cdc.gov)

It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on the relevance of toxicity and toxicokinetic data to public health. (cdc.gov)

It is important to recognize that because of the biological activity of these contaminants, dose-response relationships obtained using technical grade methoxychlor may not be directly applicable to pure methoxychlor. (cdc.gov)

the terms used were postnatal development, toxicity, rodents and physical and reflexological parameters. (bvsalud.org)

Srivastava AShivanandappa T Hexachlorocyclohexane differentially alters the antioxidant status of the brain regions in rat. (jamanetwork.com)