Giant cell arteritis (GCA), also known as temporal arteritis, is a granulomatous vasculitis that mostly affects large- and medium-sized arteries, particularly the branches of the proximal aorta. (rheumatologyadvisor.com)
Cutaneous polyarteritis nodosa (CPN) is an uncommon form of vasculitis of the small-and medium-sized arteries in the reticular dermis and subcutaneous tissue. (annals.edu.sg)
Optic1
Local ocular complications include hematoma formation, optic nerve damage and perforation of the globe with possible blindness. (wikipedia.org)
Mechanisms2
Understand the mechanisms of actions, toxicity, and proper use of the major pharmacological agents used in Internal Medicine. (xusom.com)
Through intraovarian and central adverse suggestions mechanisms, progesterone acts to suppress new follicular growth. (ehd.org)
Vasculitis2
Cutaneous polyarteritis nodosa (CPN) is an uncommon form of vasculitis of the small-and medium-sized arteries in the reticular dermis and subcutaneous tissue. (annals.edu.sg)
Central nervous system vasculitis can mimic PRES but the MRI findings are usually more diffuse and irreversible. (abcmedicalnotes.com)
Vein1
Bleeding from neovascular and fragile vessels in proliferative diabetic retinopathy, proliferative sickle cell retinopathy, ischemic retinopathy secondary to retinal vein occlusion, and retinopathy of prematurity are among the most common pathological causes of vitreous hemorrhage. (medscape.com)
Cocaine Toxicity2
1] Although nearly every organ system can be affected by cocaine toxicity, most patients present with cardiovascular complaints. (medscape.com)
Acute cocaine toxicity has three reported phases. (medscape.com)
Hemorrhage3
however, bleeding from abnormal new vessels or rupture of normal retinal vessels from direct or indirect trauma frequently is associated with vitreous hemorrhage. (medscape.com)
The second most frequent pathological mechanism for vitreous hemorrhage is tearing of the retinal vessels caused by either a break in the retina or detachment of the posterior vitreous, while the cortical vitreous is adherent to the retinal vessels. (medscape.com)
In addition, patients with sickle cell retinopathy may show a salmon-patch hemorrhage caused by blowout in the vessel wall following abrupt occlusion in the arterioles by aggregated sickled red blood cells. (medscape.com)
Neovascularization1
This condition may result directly from retinal tears or neovascularization of the retina, or it may be related to bleeding from preexisting blood vessels in these structures. (medscape.com)
Coronary1
Is evidence of myocardial infarction or coronary artery disease present? (medscape.com)
Systemic1
Systemic complications include local anesthetic toxicity, brainstem anesthesia, and stimulation of the oculocardiac reflex. (wikipedia.org)
Gastrointestinal2
Gastrointestinal Perforation and Fistula Formation: Gastrointestinal perforation and fistula, including death, have occurred. (nih.gov)
Use with caution in patients at risk for gastrointestinal perforation or fistula. (nih.gov)
Optic nerve2
Local ocular complications include hematoma formation, optic nerve damage and perforation of the globe with possible blindness. (wikipedia.org)
C3671 Traumatic Injury C99147 Neonatal Research Network Terminology C101036 Retinopathy of Prematurity with Plus Disease Retinopathy of Prematurity with Plus Disease A stage of retinopathy of prematurity characterized by the presence of the following in at least two quadrants around the optic nerve: dilation and tortuosity of major retinal vasculature as a result of increased blood flow. (nih.gov)
Syndrome9
BACKGROUND: Using rat stomach perforation as a prototypic direct lesion applied in cytoprotection research, we focused on the first demonstration of the severe occlusion/ occlusion-like syndrome induced by stomach perforation. (bvsalud.org)
The revealed stomach-induced occlusion/occlusion-like syndrome corresponds to the previously described occlusion/occlusion-like syndromes in rats suffering multicausal pathology and shared severe vascular and multiorgan failure. (bvsalud.org)
AIM: To reveal the stomach perforation-induced general occlusion/occlusion-like syndrome and BPC 157 therapy effect. (bvsalud.org)
METHODS: The procedure included deeply anesthetized rats, complete calvariectomy, laparotomy at 15 min thereafter, and stomach perforation to rapidly induce vascular and multiorgan failure occlusion/occlusion-like syndrome. (bvsalud.org)
CONCLUSION: We revealed stomach perforation as a severe occlusion/occlusion-like syndrome, peripherally and centrally, and rapid counteraction by BPC 157 therapy. (bvsalud.org)
We focused on the first demonstration that antiarrhythmics, particularly class II and class III antiarrhythmic and beta-blocker sotalol can induce severe occlusion/occlusion-like syndrome in rats. (bvsalud.org)
In this syndrome, as in similar syndromes with permanent occlusion of major vessels, peripheral and central, and other similar noxious procedures that severely disable endothelium function, the stable gastric pentadecapeptide BPC 157-collateral pathways activation, was a resolving therapy. (bvsalud.org)
BPC 157 therapy (10 µg, 10 ng/kg given intragastrically at 5 min or 90 min sotalol-time) effectively counteracted sotalol-occlusion/occlusion-like syndrome. (bvsalud.org)
Basilar artery thrombosis can present with progressive neurologic deficits and can result in tetra paresis, coma, or locked-in syndrome. (abcmedicalnotes.com)
Overdose1
Accordingly, it is appropriate to consider domestic violence when evaluating a patient for alcohol intoxication or drug toxicity and overdose. (medscape.com)
Vessels1
As in all the described occlusion/occlusion-like syndromes with permanent occlusion of major vessels, peripheral and central, and other similar noxious procedures that severely affect endothelium function, the stable gastric pentadecapeptide BPC 157 was resolving therapy. (bvsalud.org)
Rupture1
In addition to adverse effects experienced by cocaine users, body packers-people who swallow bags of cocaine in order to smuggle the drug from one country to another-may experience acute toxicity if any of the bags rupture. (medscape.com)
Chronic1
PMID- 5097490 TI - 100-day LD 50 index of chronic toxicity. (nih.gov)
Indirect1
Transscleral and indirect ophthalmoscope diode laser retinal photocoagulation: experimental quantification of the therapeutic range for their application in the treatment of retinopathy of prematurity , Graefes Arch Clin Exp Ophthalmol , vol. 231, no. 7, pp. 378-83, 1993. (uni-luebeck.de)
Wall1
C26715 Cellulitis C99147 Neonatal Research Network Terminology C101022 Cerebral Arterial Aneurysm Cerebral Arterial Aneurysm A balloon type pouch or bulge in the wall of a cerebral artery. (nih.gov)
Group1
The most common pathogenesis of bleeding in this group of disorders is believed to be retinal ischemia causing the release of angiogenic vasoactive factors, most notably vascular endothelial growth factor (VEGF), basic fibroblast growth factors (bFGF), and insulin-like growth factor (IGF). (medscape.com)
High1
Although the total dosage of ICG during the continuous injection was high, the enhancement of retinal burn and choriocapillary occlusion was small. (uni-luebeck.de)
Therapy1
At 5 min post-perforation time, rats received therapy [BPC 157 (10 µg or 10 ng/kg) or saline (5 mL/kg, 1 mL/rat) (controls)] into the perforated defect in the stomach). (bvsalud.org)
Loss1
Continue until loss of response at re-escalated dose or unacceptable toxicity. (unboundmedicine.com)