Toxicities maximum tolerated dose. Medical search. Frequent questions

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Anatomy13

Liver Cells, Cultured Kidney Cell Line Lung Cell Line, Tumor Brain Organs at Risk Bone Marrow Heart Tumor Cells, Cultured Skin Neurons

Organisms13

Rats, Sprague-Dawley Rats, Wistar Rabbits Dogs Rats, Inbred F344 Mice, Inbred BALB C Rats, Inbred Strains Mice, Inbred Strains Mice, Inbred ICR Mice, Nude Swine Guinea Pigs Cattle

Diseases37

Neoplasms Radiation Injuries Neutropenia Leukopenia Body Weight Lung Neoplasms Drug-Related Side Effects and Adverse Reactions Disease Models, Animal Thrombocytopenia Nausea Hematologic Diseases Drug-Induced Liver Injury Vomiting Breast Neoplasms Neoplasm Metastasis Neoplasm Recurrence, Local Adenocarcinoma Stomatitis Carcinoma, Non-Small-Cell Lung Neoplasms, Experimental Brain Neoplasms Recurrence Disease Progression Abnormalities, Drug-Induced Prostatic Neoplasms Gastrointestinal Diseases Plant Poisoning Drug Eruptions Head and Neck Neoplasms Neurotoxicity Syndromes Colorectal Neoplasms Drug Overdose Kidney Diseases Diarrhea Ovarian Neoplasms Melanoma Necrosis

Chemicals and Drugs81

Antineoplastic Agents Cisplatin Fluorouracil Doxorubicin Antineoplastic Agents, Phytogenic Paclitaxel Deoxycytidine Cyclophosphamide Antimetabolites, Antineoplastic Camptothecin Antibodies, Monoclonal Plant Extracts Recombinant Proteins Carboplatin Antidotes Taxoids Drug Combinations Methotrexate Etoposide Organoplatinum Compounds Antineoplastic Agents, Alkylating Leucovorin Prodrugs Antibiotics, Antineoplastic Insecticides Vinblastine Glutathione Radioisotopes Environmental Pollutants Acetaminophen Water Pollutants, Chemical Vincristine Enzyme Inhibitors Iodine Radioisotopes Drug Carriers Teratogens Carcinogens Pyridines Ifosfamide Antioxidants Cadmium Dacarbazine Antibodies, Monoclonal, Humanized Liposomes Immunosuppressive Agents Indoles Polyethylene Glycols Anti-Bacterial Agents Calcium Topotecan Radiation-Sensitizing Agents RNA, Messenger Immunotoxins Organometallic Compounds Organophosphorus Compounds Aluminum Melphalan Aerosols Cytarabine Bacterial Toxins Prednisone Radiopharmaceuticals Peptides Amifostine Endotoxins Thiazoles Bleomycin Methylmercury Compounds Neurotoxins Oxygen Quinazolines Anti-Inflammatory Agents, Non-Steroidal Herbicides Pyrroles Granulocyte Colony-Stimulating Factor Triazines Pyrazines Carmustine Reactive Oxygen Species Placebos Niacinamide

Analytical, Diagnostic and Therapeutic Techniques and Equipment78

Toxicity Tests Toxicity Tests, Acute Lethal Dose 50 Drug Administration Schedule Administration, Oral Treatment Outcome Antineoplastic Combined Chemotherapy Protocols Maximum Tolerated Dose Infusions, Intravenous Radiation Dosage Toxicity Tests, Chronic Radiotherapy Dosage Area Under Curve Radiometry Dose Fractionation Injections, Intravenous Dose-Response Relationship, Radiation Drug Evaluation No-Observed-Adverse-Effect Level Combined Modality Therapy Double-Blind Method Body Weight Radiotherapy Planning, Computer-Assisted Survival Analysis Metabolic Clearance Rate Models, Biological Disease Models, Animal Drug Evaluation, Preclinical Drug Therapy, Combination Radiotherapy, Intensity-Modulated Disease-Free Survival Survival Rate Prospective Studies Injections, Subcutaneous Radiotherapy Follow-Up Studies Chromatography, High Pressure Liquid Injections, Intraperitoneal Retrospective Studies Body Burden Toxicity Tests, Subchronic Analysis of Variance Feasibility Studies Neoplasm Staging Random Allocation Remission Induction Clinical Trials as Topic Clinical Trials, Phase I as Topic Administration, Inhalation Organ Size Drug Carriers Salvage Therapy Likelihood Functions Reproducibility of Results Animal Testing Alternatives Drug Delivery Systems Infusions, Parenteral Heart Rate Injections, Intramuscular Neoplasms, Experimental Thermoluminescent Dosimetry Blood Pressure Radiotherapy, Conformal Phantoms, Imaging Risk Assessment Biological Assay Tomography, X-Ray Computed Mutagenicity Tests Radioimmunotherapy Blood Cell Count Toxicity Tests, Subacute Leukocyte Count Radiosurgery Drug Overdose Drug Monitoring Injections Carcinogenicity Tests Placebos

Phenomena and Processes42

Lethal Dose 50 Time Factors Dose-Response Relationship, Drug Maximum Tolerated Dose Radiation Dosage Area Under Curve Dose-Response Relationship, Radiation No-Observed-Adverse-Effect Level Cell Survival Drug Interactions Half-Life Kinetics Body Weight Metabolic Clearance Rate Biological Availability Drug Synergism Biotransformation Apoptosis Pregnancy Hydrogen-Ion Concentration Organ Size Species Specificity Oxidative Stress Algorithms Tissue Distribution Temperature Mutation Heart Rate Blood Pressure Cell Death Molecular Structure Drug Tolerance Blood Cell Count Cell Division Metabolic Detoxication, Drug Structure-Activity Relationship Leukocyte Count Oxidation-Reduction Drug Resistance Drug Resistance, Neoplasm Muscle Contraction Necrosis

Disciplines and Occupations1

Technology, Industry, Agriculture3

Nanoparticles Liposomes Polyethylene Glycols

Information Science7

Radiotherapy Planning, Computer-Assisted Radiotherapy, Intensity-Modulated Survival Rate Molecular Sequence Data Algorithms Computer Simulation Radiotherapy, Conformal

Health Care26

Treatment Outcome Radiation Dosage Area Under Curve Dose-Response Relationship, Radiation Radiation Injuries Double-Blind Method Survival Analysis Disease-Free Survival Survival Rate Prospective Studies Follow-Up Studies Retrospective Studies Body Burden Analysis of Variance Feasibility Studies Random Allocation Relative Biological Effectiveness Clinical Trials as Topic Clinical Trials, Phase I as Topic Likelihood Functions Reproducibility of Results Temperature Maximum Allowable Concentration Thermoluminescent Dosimetry Risk Assessment Safety

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Technology, Industry, Agriculture Information Science Health Care

Toxicity Tests Toxicity Tests, Acute Lethal Dose 50 Drug Administration Schedule Time Factors Administration, Oral Treatment Outcome Dose-Response Relationship, Drug Antineoplastic Combined Chemotherapy Protocols Maximum Tolerated Dose Antineoplastic Agents Infusions, Intravenous Radiation Dosage Toxicity Tests, Chronic Radiotherapy Dosage Neoplasms Area Under Curve Radiometry Dose Fractionation Injections, Intravenous Cisplatin Dose-Response Relationship, Radiation Drug Evaluation Liver Radiation Injuries Fluorouracil Rats, Sprague-Dawley No-Observed-Adverse-Effect Level Cell Survival Combined Modality Therapy Drug Interactions Doxorubicin Half-Life Double-Blind Method Antineoplastic Agents, Phytogenic Kinetics Neutropenia Paclitaxel Leukopenia Deoxycytidine Cyclophosphamide Body Weight Radiotherapy Planning, Computer-Assisted Antimetabolites, Antineoplastic Survival Analysis Lung Neoplasms Drug-Related Side Effects and Adverse Reactions Cells, Cultured Metabolic Clearance Rate Rats, Wistar Models, Biological Camptothecin Toxicology Antibodies, Monoclonal Kidney Disease Models, Animal Drug Evaluation, Preclinical Drug Therapy, Combination Radiotherapy, Intensity-Modulated Plant Extracts Disease-Free Survival Biological Availability Thrombocytopenia Drug Synergism Recombinant Proteins Survival Rate Carboplatin Rabbits Nausea Prospective Studies Antidotes Dogs Injections, Subcutaneous Hematologic Diseases Taxoids Radiotherapy Rats, Inbred F344 Follow-Up Studies Drug Combinations Methotrexate Chromatography, High Pressure Liquid Etoposide Organoplatinum Compounds Injections, Intraperitoneal Retrospective Studies Body Burden Cell Line Antineoplastic Agents, Alkylating Leucovorin Drug-Induced Liver Injury Prodrugs Antibiotics, Antineoplastic Biotransformation Insecticides Vinblastine Toxicity Tests, Subchronic Analysis of Variance Lung Glutathione Radioisotopes

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