• gene
  • The aim of the present study was to investigate the mechanism of acute cellular xenograft rejection in a strain of mice with a targeted gene disruption of the toll-like receptor (TLR) signal adaptor protein MyD88. (diva-portal.org)
  • Regulation occurs at various levels of TLR signaling, from receptor ligation to gene transcription ( 7 ). (rupress.org)
  • Although
  • Although inflammatory cytokines produced by activation of Toll-like receptors (TLRs) are essential for early host defense against infection, they also mediate a vast array of pathologies, including autoimmune disease, hypersensitivity reactions, and sepsis. (rupress.org)