Tissues infectious abnormalities drug induced. Medical search. Frequent questions

Hepatobiliary tract diseases: infantile cholestasis, autoimmune and drug induced hepatitis, others. (case.edu)
HHV-4, also known as Epstein-Barr virus (EBV), causes the primary infection infectious mononucleosis , and it is implicated in various diseases, such as African Burkitt lymphoma , other immunoproliferative disorders, and nasopharyngeal carcinoma. (medscape.com)
Patients with connective tissue disease at the time of the diagnosis of CFPE were excluded from the study, as well as patients with a diagnosis of other interstitial lung diseases, such as drug-induced interstitial lung disease, pneumoconiosis, hypersensitivity pneumonitis, sarcoidosis, pulmonary histiocytosis, lymphangioleiomyomatosis and eosinophilic pneumonia 4 . (ersjournals.com)
A number of connective tissue diseases cause inflammation of the uveal tract. (msdmanuals.com)
The global burden of CVD is beginning to be viewed as high as infectious diseases [ 13 ]. (hindawi.com)
These diseases are not infectious and cannot be prevented or cured, but they be controlled - meaning the disease is not active and its signs and symptoms go away. (printo.it)
Crews and his collaborators have identified several compounds that show promise for the development of drugs to fight cancer and other diseases. (ucsc.edu)
Organoïds are advanced 3D culture systems whose structure can closely mimic organ development and various human diseases, including infectious diseases, genetic abnormalities, and cancers. (genoskin.com)
Progress in adoptive T-cell therapy for cancer and infectious diseases is hampered by the lack of readily available antigen-specific, human T lymphocytes. (benitonovas.com)
This report provides updated uniform criteria* for state health department personnel to use when reporting the nationally notifiable infectious diseases listed in Part 1 of this report. (cdc.gov)
CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)

Organoïds can be derived from various sources, including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), adult stem cells, and even primary tumor cells. (genoskin.com)
Induced pluripotent stem cells (iPSC) can now be generated from skin or blood of mice or humans by overexpressing four key transcription factors. (pas.va)
Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. (benitonovas.com)
In a first clinical trial, a natural killer cell immunotherapy derived from induced pluripotent stem cells is being tested for safety in 64 patients with a variety of solid tumors. (benitonovas.com)
The FT500 NK cells do not undergo any further alterations and after their derivation from the induced pluripotent stem cells (iPSCs), offering the possibility of a quicker, ready-made treatment. (benitonovas.com)
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) provide an accessible, genetically tractable, and homogenous starting cell population to efficiently study human blood cell development. (benitonovas.com)
The ability to induce pluripotent stem cells from committed, human somatic cells provides tremendous potential for regenerative medicine. (benitonovas.com)

The barium makes the organs more visible and can detect if there is any narrowing, inflammation, or other abnormalities that can be causing the disease. (wikipedia.org)
Recurrent bouts of inflammation are best treated with a topical corticosteroid and a cycloplegic-mydriatic drug. (msdmanuals.com)
Transbronchial lung biopsy microscopic slide of a) lung tissue showing a granulomatous inflammation with giant cell reaction and b) lung tissue under polarised light (birefringed crystalline material). (ersjournals.com)
Beyond sepsis-induced inflammation, a mechanical ventilation regimen can also propagate ventilator-related injury that may precipitate ARDS. (ceufast.com)
Trauma: Blunt force trauma, such as a vehicle accident or a fall, can induce pericardial inflammation. (petcarerx.com)

The American Thoracic Society has developed new evidence-based practice guidelines for individuals with exercise-induced bronchoconstriction. (medscape.com)
Acute prevention of exercise-induced bronchoconstriction (EIB) in patients 15 years of age and older ( 1.2 ). (nih.gov)
Pediatric use information for patients ages 6 to 14 years of age for acute prevention of exercise-induced bronchoconstriction (EIB) is approved for Merck Sharp & Dohme Corp's montelukast tablet products. (nih.gov)

In the 1960s and 1970s, scientists discovered that there are cells within adult tissues of the body that harbor many of the same special properties as embryonic stem cells. (pas.va)
embryonic stem cells , resulting from the early divisions of the egg, characterized by their "pluripotency", i.e. the capacity, that they share with the egg cell itself, to produce all the cell types found in the adult organism, and the tissue-specific stem cells present in the tissues and organs of the adult. (pas.va)

Drug-induced liver injury is a common cause of acute liver failure. (bvsalud.org)
A dose-dependent, reversible leukopenia and/or neutropenia is the predominant manifestation of hematologic toxicity associated with epirubicin and represents the most common acute dose-limiting toxicity of this drug. (recallguide.org)
Anthracycline-induced cardiac toxicity may be manifested by early (or acute) or late (delayed) events. (recallguide.org)
1 2 Similarly, soon after mechanical ventilation was instituted, unexpectedly high degrees of lung compliance in conjunction with severe hypoxemia was deemed a new 'L' phenotype of acute hypoxemic respiratory failure, attributed to an early phase 'dry lung' with measured 'hyperperfusion of gasless tissue' as opposed to the significant alveolar oedema and resulting hypoxic vasoconstriction observed in 'traditional' acute respiratory distress syndrome (ARDS). (bmj.com)

Based on the patient's history and the clinical, radiological, histological and mineralogical findings, and by the exclusion of other plausible causes, the diagnosis of talc induced interstitial lung disease (talcosis) was made based on abundant use of cosmetic talcum powder. (ersjournals.com)

Other causes include: Medicines - Can cause esophageal damage that can lead to esophageal ulcers Nonsteroidal anti-inflammatory drugs (NSAIDS) - aspirin, naproxen sodium, and ibuprofen. (wikipedia.org)
Dermatologists play an essential role in this process given the significant incidence of inflammatory dermatoses, as well as skin and soft tissue infections (SSTIs) treated with antibiotics. (skintherapyletter.com)
Neutrophils, though increasingly linked to the development of inflammatory disorders, have been less well studied in relation to TB-induced lung pathology. (frontiersin.org)
The inflammatory cells from the blood stream gather in the vessel wall, causing more damage to the vessel and to the surrounding tissue as well. (printo.it)
Fungal keratitis is a serious infectious keratopathy related to fungal virulence and excessive inflammatory responses. (researchsquare.com)

Liver biopsy on POD 7 showed no evidence of rejection, biliary complications or drug-induced liver injury. (cdc.gov)
On the basis of the above researches, we hypothesized that serum miR-122 can act to evaluate conditions HBV-induced liver injury at different stages. (hindawi.com)
It is, therefore, not a highly specific indicator of liver injury as its elevation can occur as a result of other injured tissues. (medicinenet.com)

However, infections can be spread by those who have infectious esophagitis. (wikipedia.org)
Commonly, this stems from unclear instructions on self-administration of antibiotics, use of sub-antimicrobial dosing, prescription of antibiotics for minor bacterial infections, use of antibacterial drugs for non-bacterial infections, and use of broad-spectrum antibiotics for narrow-spectrum indications. (skintherapyletter.com)
The findings will help to identify drugs that cure otherwise lethal infections. (nih.gov)
4 However, OP more commonly results from infections (especially viral), drugs or autoimmunity, when the term secondary OP applies. (bmj.com)

CMV infection has been shown to induce transient abnormalities of in vitro cellular-immune function in otherwise healthy human hosts (2,3). (cdc.gov)
Both topical and systemic monotherapy may induce resistance among Cutibacterium acnes (C. acnes) and other organisms that comprise the commensal and transient flora. (skintherapyletter.com)
Leukopenia/neutropenia is usually transient, with WBC and neutrophil counts generally returning to normal values by Day 21 after drug administration. (recallguide.org)
This can vary from a transient minor decrease of blood flow to complete occlusion with subsequent changes to the unsupplied tissue caused by the lack of oxygen and nutrient supply. (printo.it)

IT IS well established that glucocorticoids exert catabolic effects on connective tissue and delay wound healing. (deepdyve.com)

Infection of other cell types possessing ACE2 receptors has been described including the epithelial cells of the lung, intestine, kidney, heart, and blood vessels inducing cardiotropic damage [ 4 , 5 ]. (springer.com)
The vessel wall itself becomes more "leaky", allowing the fluid from within the blood vessels to enter the surrounding tissues and causing swelling. (printo.it)
The abnormalities of the vessel shape in the larger arteries can be detected through angiography (a radiological investigation procedure that allows us to see the blood vessels). (printo.it)

Acquired forms are generally caused by such extrinsic (extracellular) defects as infection, systemic disease, drugs or toxins, liver or kidney disease, or abnormal immune responses. (innvista.com)

Chronic HBV carriers can be defined as those people in the immune tolerance phase who are positive for HBsAg, HBeAg, and HBV DNA and have normal liver function and no obvious abnormalities in the liver histology, and this situation might be maintained for several years or even decades [ 4 , 5 ]. (hindawi.com)
HHV-5, also known as cytomegalovirus (CMV), causes a primary infection of the salivary glands and other tissues, and it is believed to have a chronic form. (medscape.com)
Severe chronic cases may require noncorticosteroid immunosuppressive drugs (eg, methotrexate , mycophenolate mofetil). (msdmanuals.com)
Given the chronic nature of disease and risk of treatment-related cataract and glaucoma development, long-term control often requires use of a noncorticosteroid immunosuppressive drug (eg, methotrexate , mycophenolate mofetil). (msdmanuals.com)
Patients who have recovered from coronavirus disease 2019 (COVID-19) infection may experience chronic fatigue when exercising, despite no obvious heart or lung abnormalities. (mdpi.com)
Obviously, both of these modalities can have substantial limitations for the diagnosis of a chronic infectious disease. (vin.com)

In contrast, macrocytic anemias most commonly originate from abnormalities that impair erythroid precursors' maturation in the bone marrow. (eistria.com)

When pulmonary involvement is investigated systematically, prevalence ranges between 43% and 75% [ 9 ] and on HRCT of the chest abnormalities are found in 34-50% of the patients [ 10 ]. (ersjournals.com)
Pulmonary vessels showed no abnormalities. (ersjournals.com)
Neutrophils mode of action and their specialized functions can be directly linked to TB-specific lung tissue damage observed on patient chest X-rays at diagnosis and contribute to long-term pulmonary sequelae. (frontiersin.org)

Diagnosis of extrapulmonary TB is more difficult because it requires tissue biopsies or body fluids (e.g., spinal fluid) that usually contain only a few organisms. (cdc.gov)
Exercise-induced asthma is generally a clinical diagnosis. (medscape.com)

infection occurs when susceptible persons inhale infectious droplets produced by the exhalations of persons with respiratory tract TB. (cdc.gov)
Therefore, it is of utmost importance to establish the frequency of infection of heart tissue in COVID-19 patients with multiple presentations of the disease. (springer.com)
When we review the spectrum of disease manifestations attributed to E. canis infection, there is considerable variation in the type, duration, and severity of historical, physical, and clinicopathologic abnormalities reported in naturally infected dogs. (vin.com)
Whether the substantial variation in disease manifestations or clinicopathologic abnormalities reflect strain differences in pathogenicity, variability in the immunologic response of the host to the rickettsia, co-infection with other tick-transmitted pathogens, or other unknown factors remains unclear. (vin.com)

Although the causes of death were varied, most of the deaths appeared to be either cardiovascular (e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature. (nih.gov)
We believe that clinicians have not sufficiently considered the condition of 'viral-induced secondary organising pneumonia (OP)', largely due to the fact that OP in its idiopathic form, called cryptogenic organising pneumonia (COP), is a rare and clinically unique disease often misunderstood and poorly recognised even by pulmonologists. (bmj.com)

The patient has been treated with 2 short courses of TMP/SMX that have been limited because of a sulfa-induced neutropenia. (cdc.gov)
Supportive care may be necessary for the treatment of severe neutropenia and severe infectious complications. (recallguide.org)

Penetration of antiretroviral drugs into the lung and other tissues has been shown for tenofovir in animal models (35) and for tenofovir, FTC, 3TC, and efavirenz in humans (36). (natap.org)
As a second method of analysis, an inner comparability is made between the chance of start defects amongst ladies with first trimester exposures to antiretroviral drugs and the danger of birth defects amongst women with second or third trimester exposures to antiretroviral medicines. (ehd.org)

Additionally, a recent retrospective study reveals the negative effect of drug-resistance and disease recurrence on PIAT ( 15 ). (frontiersin.org)

However, these adult stem cells have more restricted potential - they are specialized to replenish, rejuvenate, and repair the tissues in which they reside. (pas.va)
These adult stem cells are highly specialized and can only produce the tissue in which they reside. (pas.va)
Significant advances have been made in isolating, culturing and reintroducing adult stem cells into tissues. (pas.va)

Routine donor biopsy did not show any histopathologic abnormality. (cdc.gov)
Transplanted liver tissue biopsy specimen on postoperative day 30 from donor in cluster of donor-derived cryptococcosis, China. (cdc.gov)
This can be seen in tissue biopsy samples. (printo.it)

Chest X-rays: Chest X-rays can assist your veterinarian in visualizing the size and form of your cat's heart as well as assessing for any fluid buildup or abnormalities. (petcarerx.com)

Postmortem examination showed no evidence of Hodgkins disease, but P. carinii and CMV were found in lung tissue. (cdc.gov)

They are particularly active in tissues and organs in which the lifespan of the differentiated cells is short, like blood, skin and the inner cell layer covering the intestinal cavity, as well as in the repair of skeletal muscle after exercise of injury. (pas.va)
OP is a histological pattern of lung injury characterised by the filling of alveoli and alveolar ducts with spindle-shaped fibroblasts and myofibroblasts that later form granulation tissue. (bmj.com)

Rickettsial organisms in general, and Ehrlichia species in particular, are difficult to isolate from animals or human patients using conventional tissue culture systems. (vin.com)
Most tick-transmitted pathogens require a 24 to 48 hour period of attachment to the host before there can be successful transmission of infectious organisms. (vin.com)

It is believed to chronically persist in salivary gland tissue in some hosts, and oral shedding is the probable route of disease transmission. (medscape.com)
Using genome-wide assays, we identify cancer-related epigenetic abnormalities that arise early during reprogramming and persist in induced pluripotent stem cell (iPS) clones. (benitonovas.com)

These include hundreds of abnormal gene silencing events, patterns of aberrant responses to epigenetic-modifying drugs resembling those for cancer cells, and presence in iPS and partially reprogrammed cells of cancer-specific gene promoter DNA methylation alterations. (benitonovas.com)

However, a recent trial showed the efficacy of the antifibrotic drug nintedanib in slowing progression of various ILDs, including those in pSS patients. (ersjournals.com)
Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. (nih.gov)
Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. (nih.gov)
Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about 4.5%, compared to a rate of about 2.6% in the placebo group. (nih.gov)
The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. (nih.gov)
Hyperlipidemic patients should be warned about the potential risks of herb-drug interactions, particularly those taking anticoagulants and antiplatelet drugs. (hindawi.com)

It is released into the serum when any one of these tissues is damaged. (medicinenet.com)

Erythrocytes' role is to deliver oxygen from the lungs in tissues and carbon dioxide from tissues into the lungs. (eistria.com)

In contrast to TDF (33), phosphorylated tenofovir concentrations in genital tract and rectal tissue achieved with TAF were almost unquantifiable in healthy seronegative volunteers (34). (natap.org)

Treatment requires a topical corticosteroid and a cycloplegic-mydriatic drug. (msdmanuals.com)

Lesions develop through a progressive compression of the healthy tissue, progressively resulting in irreversible renal failure. (vin.com)

In the last few decades, hundreds of Chinese herbal medicines in the form of compounds, extracts, single herbs, or formulae have been reported to be effective for the prevention and treatment of hyperlipidemia [ 16 ], especially those high-fat diet (HFD) induced cases. (hindawi.com)

Hereditary forms are the result of intrinsic (cellular) abnormalities, typically of the erythrocyte's plasma membrane or cytoplasmic contents (enzymes of hemoglobin). (innvista.com)

AST (SGOT) is normally found in a variety of tissues including the liver, heart , muscle, kidney, and brain. (medicinenet.com)

coronary artery Either of the 2 main arteries that supply the tissues of the heart with oxygen-rich blood. (zlibrary-global.se)

Normochromic normocytic anemias have different etiologies: in some of these anemias, specific erythrocyte-shaped abnormalities observed on the peripheral blood smear provide an important etiological signpost. (eistria.com)

Fungal keratitis is a serious infectious keratopathy with a high incidence of vision loss, which is mainly caused by Fusarium and Aspergillus (Huang et al. (researchsquare.com)
2019 ). However, due to the insufficiency and severe side effects of antifungal drugs, fungal keratitis has a poor prognosis. (researchsquare.com)

Due to increasing popularity of TCM, more extensive, well-designed preclinical and clinical trials on the potential synergistic and adverse side effects of herb-drug interactions as well as their mechanisms are warranted. (hindawi.com)

They induce skin atrophy partly by decreasing the proliferative capacity of skin fibroblasts and the synthesis of the ground substance. (deepdyve.com)

Bronchoalveolar lavage was negative for mycobacteria and other infectious agents, and no neoplastic cells were found. (ersjournals.com)

Life-threatening CHF is the most severe form of anthracycline-induced cardiomyopathy. (recallguide.org)

Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. (nih.gov)
Most of single herbs and formulae demonstrated the improvement of hyperlipidemic conditions with multiple and diverse mechanisms of actions similar to conventional Western drugs in spite of their mild side effects. (hindawi.com)

Early cardiac toxicity of epirubicin consists mainly of sinus tachycardia and/or ECG abnormalities such as non-specific ST-T wave changes, but tachyarrhythmias, including premature ventricular contractions and ventricular tachycardia, bradycardia, as well as atrioventricular and bundle-branch block have also been reported. (recallguide.org)
This toxicity appears to be dependent on the cumulative dose of Epirubicin Hydrochloride Injection and represents the cumulative dose-limiting toxicity of the drug. (recallguide.org)
The imperative for accurate, ethical, and human-relevant methods to assess the toxicity and tolerance of new drug candidates has never been more crucial. (genoskin.com)
Primary cells are also generally more representative of how cells in the body respond to drugs, making them more suitable for drug development and toxicity testing. (genoskin.com)

Familial AN, drug-induced AN, AN occurring in hyperinsulinemic states (eg, diabetes, obesity), AN associated with polycystic ovary disease, and AN associated with a spectrum of autoimmune disease in women should be considered before AN is determined to represent a paraneoplastic syndrome. (medscape.com)
This project aims to achieve a paradigm shift in antimicrobial drug discovery by finding next generation anti-infectives that prevent disease by blocking pathogen adaptation to host physiology. (nih.gov)
Rather than simply preventing bacteria from growing, these new sophisticated drugs will prevent disease by interfering with a microbe's ability to interact with the human body. (nih.gov)
Tuberculosis (TB) is the single deadliest infectious disease known to man with 10 million new cases and 1.6 million deaths (including 300,000 HIV coinfected) in 2018 ( 1 ). (frontiersin.org)

Toxics include industrial or domestic products such as glycol ethylene, house plants (Lilium ), weed killers, pesticides, solvents, but mainly drugs such as aminoglucosode sulfamides and above all NSAIDs. (vin.com)

Lined by stratified squamous epithelium, the tissues of the mouth are often involved when individuals have conditions affecting the GI system. (medscape.com)
Case definitions for some infectious conditions not designated as nationally notifiable are included in Part 2 of this report. (cdc.gov)

Echocardiogram: This imaging test creates detailed images of the heart and surrounding tissues by using ultrasonic waves. (petcarerx.com)

They will take this work one step further and create new model systems to determine the 3-D relationships and functions of different epithelial cell types as the basal cells detect and respond to various drugs, hormones, chemicals and pathogens that appear in the cavity of the organ. (nih.gov)

Our Lithostat (acetohydroxamic acid) Tablets Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)

Serious research into the therapy for brain cancer started almost 20 years ago after cancer biologist WaldemarDebinski, then at Penn State, discovered that the receptor for the immune signaling molecule interleukin 13 (IL-13) was present on glioblastomas, but not on healthy brain tissue. (benitonovas.com)

However, due to Merck Sharp & Dohme Corp's marketing exclusivity rights, this drug product is not labeled with that pediatric information. (nih.gov)

it is rarely done on intraocular tissues because of the risk associated with the procedure. (msdmanuals.com)

Anatomy50

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Phenomena and Processes67

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Anthropology, Education, Sociology and Social Phenomena1

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