Tissues embryonic stem cells. Medical search. Frequent questions

We portrayed the Notch system in embryonic stem cell (ESC)-derived embryoid bodies (EBs) differentiating under the standard protocols used to assess yolk sac (YS) hematopoiesis in vitro. (karger.com)
At this time I also began working with mouse and human embryonic stem cells resulting in the publication of some of the first papers describing the osteogenic differentiation of mouse ES and human cells in vitro and in vivo . (nottingham.ac.uk)
Hematopoietic Stem Cell and Leukaemic Stem Cell environmental stress responses (In vitro biomimicry of hypoxia, normoxia, hypothermia, hyperthermia, hypoglycemia and hyperglycemia): Effect on cellular growth, cell cycle distribution, apoptosis and cellular metabolism. (imperial.ac.uk)
A gene for a green fluorescent protein was inserted into the genomes of stem cells, which were then injected into macaque embryos grown for around four days in vitro. (planer.com)
An idea just in the planning stage is to select embryonal stem cells (ESCs) in vitro for phenotypes that may retard aging. (jax.org)
Federal financing would still be restricted to stem cell lines derived from embryos that were slated to be discarded by in vitro fertilization clinics. (consumerwatchdog.org)
The President's Council on Bioethics , in its January 2004 report, observes , 'Embryonic stem cells are capable of becoming many different types of differentiated cells if stimulated to do so in vitro (outside the body). (freerepublic.com)
However, 'it is not known for certain that human embryonic stem cells in vitro can give rise to all the different cell types of the adult body. (freerepublic.com)
Mouse nuclear transfer embryonic stem cells (NT-ESCs) were first established in 2000, and then proved to be able to differentiate either in vivo or in vitro, and give rise to individual tissues through germ line transmission or tetraploid complementation. (benthamscience.com)
Discuss how we can use stem cells combined with biomaterials for in vitro and in vivo applications. (manchester.ac.uk)
However, MSCs need to be expanded in vitro in order to obtain sufficient cells for clinical trials since they are extremely rare in various tissues. (hindawi.com)
Unlike embryonic stem cells, adult stem cells (MSCs) have a limited lifespan and stop proliferating during in vitro culture due to replicative senescence [ 8 ]. (hindawi.com)
The techniques that we use range from single molecule mechanics, (immuno) electron microscopy, exon microarray analysis, in vitro motility assays, low angle X-ray diffraction, cell physiology (including calcium imaging), muscle mechanics, and isolated heart physiology. (bio5.org)
Understanding how stem cells behave in the niche is extremely important in order to extract these cells from their natural habitat, expand them in vitro and transplant the stem cells back to the patient, to repair and/or regenerate tissues and organs, with no risks to the individual's integrity. (bvsalud.org)
To complement the in vivo system of chick embryos, we employ patient omics data, single cell RNA sequencing, human and mouse embryos, human cancer cell cultures, human pluripotent stem cells, chick embryo neural crest-derived in vitro crestosphere cultures, and zebrafish and mouse in vivo models. (lu.se)
To determine how the pathogenesis of these viruses differs, we compared their ability to induce disease in mice and replicate and induce cell death in vitro. (cdc.gov)
In vitro toxicity data of these metabolites derived in the development of validated and accepted in vitro and in silico embryonic stem cell test were used as input in the PBK model to extrapolate in vitro concentration-response curves to predicted approaches is urgently needed. (cdc.gov)

Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures. (ca.gov)
These data establish that subpopulations of proliferating hESCs whose tissue fate is predetermined exist, and challenge the notion that all cells within proliferating hESC cultures are truly 'pluripotent. (ca.gov)
Embryonic stem cells are known as pluripotent stem cells. (healthline.com)
Scientists have recently discovered how to turn adult stem cells into pluripotent stem cells. (healthline.com)
These new types of cells are called induced pluripotent stem cells (iPSCs). (healthline.com)
Since rodent models cannot recapitulate many of the human disease features, human induced pluripotent stem cells derived from Parkinson's patients have been used to generate brain organoids, greatly contributing to our understanding of the disease pathophysiology. (nature.com)
Researchers call stem cells 'pluripotent' cells, meaning that any given stem cell can become any of several types. (sciencedaily.com)
In this study, we have provided strong evidence that naïve monkey pluripotent stem cells possess the capability of differentiating in vivo into all the various tissues composing a monkey body,' co-author Professor Miguel Esteban from the University of Chinese Academy of Sciences, Guangzhou, China told Nature. (planer.com)
Kuldip S. Sidhu , " Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside ", Bentham Science Publishers (2012). (benthamscience.com)
Induced pluripotent stem cells, another types of pluripotent stem cells derived from any tissue by reprogramming and are the homologous source of stem cells. (benthamscience.com)
The unit will demonstrate various types of stem cells: adult, embryonic, induced pluripotent and their specialised culture methods. (manchester.ac.uk)
These progenitors which are derived from either embryonic stem cells (ESCs) or healthy induced pluripotent stem cells (iPSCs) express wild-type levels of a-syn, thus making them equally susceptible to developing Lewy bodies over time. (lu.se)
Direct neuronal reprogramming of a somatic cell into therapeutic neurons, without a transient pluripotent state, provides new promise for the large number of individuals afflicted by neurodegenerative diseases or brain injury. (lu.se)
No evidence of tumour formation was observed in the transplanted animals, a major concern when utilising a pluripotent cell source. (lu.se)
Firstly, we present a robust 2-week protocol for the differentiation of human pluripotent stem cells (PSCs) into forebrain neural progenitor cells. (lu.se)

In recent years, several competing viewpoints have emerged about embryonic stem cell research. (ipl.org)

Scientists announced this week that they have successfully produced embryonic stem cells by transferring the DNA of human skin cells into unfertilized human eggs to produce embryos, a technique the Church considers to be an abuse of human life. (womenofgrace.com)
Embryonic stem cell research "uses special cells found in three-to-five day old human embryos to seek cures for a host of chronic disease" (PRC). (ipl.org)
Embryonic stem cells come from human embryos that are three to five days old. (healthline.com)
But creating the stem cells now involves the destruction of human embryos, which some people, including Mr. Bush, say is immoral. (consumerwatchdog.org)
Even under the new legislation, scientists said, they could still not use federal money to create new cell lines if it involved the destruction of embryos. (consumerwatchdog.org)
Embryonic stem cells are derived from early embryos and have the ability to differentiate into any cell type. (spiked-online.com)
Embryonic stem cells come from pulling apart human embryos, and thus have aroused ethical concerns. (freerepublic.com)
The issue of research involving stem cells derived from human embryos is increasingly the subject of a national debate and dinner table discussions," said President George W. Bush in a 2001 speech announcing his policy on embryonic stem cell research. (erlc.com)
Where do the embryos for embryonic stem cells come from? (erlc.com)
Currently, all human embryonic stem cell lines in use today were created from embryos generated by IVF. (erlc.com)
Depending on the source, stem cells can be classified into two broad categories i.e. embryonic stem cells that are derived from embryos and non-embryonic stem cells that are derived from adult and fetal tissues. (benthamscience.com)
The cells used are derived from adult tissue such as fat, or bone marrow, thereby circumventing the ethical concerns raised by the use of cells derived from embryos. (ibtimes.com)

Mesenchymal stem cells (MSCs) possess great therapeutic potential. (hindawi.com)
The differentiation of mesenchymal stem cells (MSCs) into multiple cell lineages can be exploited as an attractive strategy for cell-based therapy and regenerative medicine [ 1 ]. (hindawi.com)
At BioXcellerator, our protocols are based on a specific type of stem cell - mesenchymal stem cells from donated umbilical cords. (maxim.com)
Mesenchymal stem/stromal cells (MSC) are the ideal source to study fat formation as they are the progenitors of adipocytes. (mdpi.com)
RepliCel Life Sciences Inc. today announced that it has been granted a patent by Japan's Ministry of International Trade and Industry for hair follicle mesenchymal stem cells and their use thereof. (baldingblog.com)

Eventually, the cells begin to differentiate, taking on a certain function in a part of the body. (healthline.com)
Adult stem cells can't differentiate into as many other types of cells as embryonic stem cells can. (healthline.com)
They can differentiate into all types of specialized cells in the body. (healthline.com)
The breakthrough has created a way to "de-differentiate" the stem cells. (healthline.com)
Studies showed that any given population of ESCs could be very heterogeneous and that their potential pluripotency, or capacity to differentiate into other cell types, could vary both among cells from the same embryo and from one lineage to another. (eurekalert.org)
In the early embryo, embryonic stem cells give rise to all of the cell types in the organism, including adult stem cells, which continually replace cells in the adult tissues that die or differentiate into more mature cells like red blood cells. (sciencedaily.com)
Embryonic stem cells are intriguing because they can differentiate into any of the specialized tissue cells of the body. (latimes.com)
Embryonic stem cells are able to differentiate into a variety of different tissues. (lbl.gov)
Stem cells are characterised by their unique ability to constantly renew themselves and differentiate into a diverse range of other specialised cell types. (derstandard.at)
As stem cells within a developing human embryo differentiate within the cell, their capacity to diversify generally becomes more limited and their ability to generate many differentiated cell types also becomes more restricted. (erlc.com)
By learning how stem cells differentiate and become specialized, scientists hope to gain a better understanding of how cells in general work and what can go wrong. (erlc.com)
Adult stem cells are sometimes referred to as somatic stem cells to differentiate them from human germ cells, sperm cells and egg cells. (erlc.com)
Tissue regeneration occurs due to the proliferation of stem cells, which can not only divide, but also differentiate into cells of the tissue whose regeneration is taking place. (vechnayamolodost.ru)
Dental pulp stem cells have been isolated from deciduous and permanent teeth and have the potential to self-renew and differentiate. (bvsalud.org)
We show that human and chimpanzee cells differentiate in a similar man¬ner and that the difference in interspecies protein abundance is higher than transcript-level differences, suggesting that post-transcriptional mechanisms play a role in the difference between human and chim¬panzee brain development. (lu.se)

Directed differentiation of human embryonic stem cells (hESCs) has generated much interest in the field of regenerative medicine. (ca.gov)
He is also interim president of the state's new stem cell agency, the California Institute for Regenerative Research. (latimes.com)
For more than half a century, the regenerative possibilities of stem cells - which the body stores to repair damaged tissue and organs and restore blood supply - have tantalized the medical community. (truthdig.com)
Although many breakthroughs have been reported and hailed in scientific journals over the years, the number of regenerative medicine treatments in medical use today is still limited and the efficacy is variable and transient because more comprehensive investigation is required for understanding the biology of tissue-repair and regeneration and the cellular mechanism of stem cell niche. (techscience.com)
The focus of this special issue is to capture the current advances in cell membrane repair and stem cell regenerative biology. (techscience.com)
In adults, stem cells act as a repair system for the body, replenishing specialised cells, and maintaining the normal turnover of regenerative organs such as blood, skin or intestinal tissues. (derstandard.at)
If stem cells can be used to produce new and differentiated cells that are damaged because of disease (such as Parkinson's disease) or injury (e.g., spinal cord damage), it would transform regenerative medicine. (erlc.com)
Stem cells are emerging as an important source of material for diseases in regenerative medicine. (benthamscience.com)
The study of biology of stem cells is the hallmark of the recent emerging field of regenerative medicine and medical biotechnology. (benthamscience.com)

Embryonic stem cells (ESCs) can give rise to many different types of tissues and organs. (eurekalert.org)
At the turn of the present century, these cells were believed to offer hope of treatment for several health problems, but as research advanced, scientists realized that understanding and controlling the behavior of ESCs would be a more daunting challenge than initially imagined. (eurekalert.org)
Researchers at the Center for Cell-Based Therapy (CTC) in Ribeirão Preto, São Paulo State, have now investigated the functioning of 31 miRNAs observed in human ESCs and identified signaling pathways involved in both pluripotency and differentiation. (eurekalert.org)
According to Panepucci, the human ESCs used in scientific research are usually in the intermediate development stage of primed pluripotency, when they have not yet differentiated but are primed, i.e., a step closer to assuming a distinct cell identity. (eurekalert.org)
At this stage, they are less versatile than mouse ESCs, which are typically isolated when the cells are naive and hence widely used as a research model. (eurekalert.org)
ESCs are immortal, but develop into normal tissues, including germ cells, after injection into an early embryo. (jax.org)
There is no disagreement among experts about the capacity of (ESCs) to form any and all cells and tissues of the body,' Groopman declares. (freerepublic.com)
Embryonic stem cells (ESCs) are stem cells that have been taken from the inner cell mass of a blastocyst, an embryo of about 150 cells that has not yet implanted into a woman's uterus. (erlc.com)
Embryonic stem cells (ESCs) can grow infinitely and give rise to all types of cells in human body, thus of tremendous therapeutic potentials for a variety of diseases, such as Parkinson's disease, spinal cord injury, and diabetes. (benthamscience.com)
However, tissue rejection following ESCs derivatives transplantation greatly hinders its application. (benthamscience.com)
What is more, by deriving NT-ESCs from patient cells, the problem of immune rejection may be avoided. (benthamscience.com)

Embryonic stem cell transplants have been an ethical, social, and legal controversy since the first successful transplant of human stem cells in 1998. (ipl.org)
Doctors have been performing stem cell transplants, also known as bone marrow transplants, for decades using hematopoietic stem cells in order to treat certain types of cancer. (healthline.com)
Bone marrow transplants for cancer patients, which rely on blood stem cells, fulfill this potential. (truthdig.com)
Transplantations of fetal tissue in the 1980s and 1990s provided proof-of-concept for the potential of cell replacement therapy for PD and some patients benefitted greatly from their transplants. (lu.se)

Reversible Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Mouse Embryonic Stem Cells. (ca.gov)
Here, we profile the DNA methylome, transcriptome, and global occupancy of histone modifications (H3K4me1, H3K4me3, H3K27me3, and H3K27ac) in a series of mouse embryonic stem cells (mESCs) with varying DNA methylation levels to study the effects of DNA methylation on deposition of histone modifications. (ca.gov)
Mouse embryonic stem cells are known to be tumorigenic - that is, they can grow uncontrollably and become cancerous. (spiked-online.com)
physiologically based animals because a mouse embryonic stem cell line is used. (cdc.gov)
the EST, which assesses the effects of compounds on the differentiation of mouse embryonic stem cells into contracting cardiomyocytes, can be used to rank the potency of chemicals within a series of alkoxyacetic acid metabolites formed from The implementation of the European REACH (Registration, glycol ethers. (cdc.gov)

To understand the multifaced aspects of Parkinson's disease, it may be desirable to expand the complexity of these models, to include different brain regions, vasculature, immune cells as well as additional diverse organ-specific organoids such as gut and intestine. (nature.com)
Researchers investigating many other conditions, including Parkinson's , also have been known to use embryonic stem cells. (salon.com)
Scientists hope one day to produce tissues to repair the damage caused by Parkinson's disease, diabetes and other diseases. (consumerwatchdog.org)
Scientists anticipate that in the future stem cell lines will provide a virtually unending supply of pancreatic cells for diabetic patients, neuronal cells for patients with neural disorders such as Parkinson's or Alzheimer's disease, and a host of heart cells that may treat a variety of cardiac problems. (spiked-online.com)
The ultimate aim is to develop these cells and technologies for use in brain repair, with focus on Parkinson's disease. (lu.se)
Therapies based on the application of stem cells have great potential in the prevention and treatment of several diseases, such as cancer, diabetes, cardiovascular disease, spinal cord injuries, neurological diseases such as Parkinson's and Alzheimer's, and in the regeneration of various tissues and organs. (bvsalud.org)
Shane Grealish: Cell Replacement Therapy for Parkinson's Disease: The Importance of Neuronal Subtype, Cell Source and Connectivity for Functional Recovery. (lu.se)

Therapeutic cloning, which creates embryonic stem cells . (medlineplus.gov)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
Nor could federal money be used for therapeutic cloning, in which stem cells are created from a body cell of a person. (consumerwatchdog.org)
Such therapeutic cloning might be used to create stem cells from people with specific diseases. (consumerwatchdog.org)
A renewable, tissue culture source of human cells capable of differentiating into a wide variety of cell types would have broad applications in basic research and therapeutic techniques. (spiked-online.com)
So we decided to use these stem cells in association with an artificial, netlike matrix to support formation of functional tissue-like structures that can be used in a new therapeutic approach to repair the heart. (derstandard.at)
In this regard, cell-based therapy may be an alternative therapeutic approach. (lu.se)

Current screening of potential new drugs is done using cell lines derived from animals or 'abnormal' human tissue such as tumor cells. (spiked-online.com)
It turned out that old cells, on the one hand, act as tumor suppressors (since they irreversibly stop dividing themselves and reduce the risk of transformation of surrounding cells), and on the other hand, the specific metabolism of old cells can cause inflammation and degeneration of neighboring precancerous cells into malignant ones. (vechnayamolodost.ru)
After successful completion of the module, students will have in-depth knowledge of cell biology and molecular biology from all aspects of tumor biology. (tum.de)
TS-REX was applied to predict regulators of Polycomb group genes in six human tumor tissues and in human embryonic stem cells. (lu.se)
We are intrigued by how we can utilize the setting of normal embryonic development to understand tumor initiation. (lu.se)

These stem cells come from developed organs and tissues in the body. (healthline.com)
Sex differences in the human body affect many different organs and tissues, some of them have an effect on the human brain and its development. (dissertations.se)
Currently, clinical trials are underway of drugs that selectively eliminate old cells in organs and tissues, thereby preventing degenerative changes in organs and cancer. (vechnayamolodost.ru)
Stem cells that exist in almost all organs and tissues are able to divide indefinitely. (vechnayamolodost.ru)

Buaas and Braun agreed that it sounded as if the mice were born with germ stem cells, the cells that produce sperm, but then lost their germ line early in puberty. (sciencedaily.com)
This is happening in natural killer cells, T cells, dendritic cells from human skin, and epidermal stem cells in mice," says Samantha B. Larsen, a former graduate student in the laboratory of Elaine Fuchs at The Rockefeller University. (scitechdaily.com)
So the Fuchs lab once again exposed mice skin to irritants, and watched as stem cells in the skin changed. (scitechdaily.com)
The strain is now valued as a source of embryonic stem cells for making knockout mice. (jax.org)
I am investigating a human connective tissue disorder in mice. (bio5.org)
I also describe the development of a novel behavioural task that is predictive of mesDA neuron cell loss in mice. (lu.se)

During a recent appearance on the Oprah Winfrey show, the popular cardiovascular surgeon and television personality, Dr. Mehmet Oz, announced to a stunned audience that due to advances in adult stem cell technology, the debate over embryonic stem cells "is dead. (womenofgrace.com)
For example, hematopoietic stem cells are a type of adult stem cell found in bone marrow. (healthline.com)
So it is with their current combined attack on adult stem cell research, designed to support the alternative of embryonic stem cells . (freerepublic.com)
The result says Chris Mooney in the Washington Monthly is that 'conservatives have latched onto fringe science in order to advance moral arguments' by embracing adult stem cell research. (freerepublic.com)
Amazingly, there are also more than 300 adult stem cell clinical trials . (freerepublic.com)
Embryonic stem cell propagandists will tell you adult stem cell research had a huge head start and embryonic stem cells only need time (and more importantly, massive government funding) to catch up. (freerepublic.com)
Dozens of adult stem cell treatments are moving through clinical trials and showing early success, raising hopes that some could reach the market within five years. (ibtimes.com)
Some adult stem cell niches have already been described, but the majority of them remain unclear, including the dental pulp stem cell niches. (bvsalud.org)

Publishing their results in Cell, the authors analysed 26 different tissues, showing that donor cells accounted for 21 to 92 percent of the constituent cells, with an average incidence of 67 percent. (planer.com)
The use of expression levels of transcription factor-encoding genes according to hierarchical anatomical classifications covering different tissues and cell types makes it possible to filter out irrelevant binding site predictions and to identify candidates of potential functional importance for further experimental testing. (lu.se)

This means that CSCs represent a logical source for cardiac regeneration therapy because, unlike other adult stem cells, they are intrinsically programmed to generate cardiac tissue in the lab and thus increase cardiac tissue viability in humans. (derstandard.at)
We then joined the cardiac tissue built from the mesh scaffold onto the diseased structure of the heart to stimulate the regeneration of the optimal cell types for that particular portion of the heart. (derstandard.at)
Second, stem cells may prove to be an indispensable source of transplantable cells and tissues for repair and regeneration. (erlc.com)
During cell division, tissue rejuvenation occurs: new cells take the place of damaged ones, while repair (elimination of DNA damage) occurs more intensively and regeneration is possible in case of tissue damage. (vechnayamolodost.ru)
Likewise, the knowledge of stem cell biology is crucial to the development of stem cell therapies, based on tissue engineering applied to dentistry, seeking the regeneration of dental tissues damaged or lost by caries, trauma or genetic diseases. (bvsalud.org)

Noninvasive detection and imaging of molecular markers in live cardiomyocytes derived from human embryonic stem cells Biophysical Journal. (nottingham.ac.uk)

The U.S. Food and Drug Administration (FDA) has approved the world's first human clinical trial of a therapy involving embryonic stem cells, a move that has been condemned by the Vatican as "unacceptable. (womenofgrace.com)
There are major obstacles to overcome before a stem cell line is liable to reach clinical trials. (spiked-online.com)
The number of clinical trials involving embryonic stem cells? (freerepublic.com)
The non-embryonic stem cells like adult stem cells are in clinical use for many years and embryonic stem cells are now emerging as an alternative source for the same purpose with huge potentials in drug discovery and toxicological studies. (benthamscience.com)
The clinical application of MSCs to tissue engineering has been introduced due to their numerous advantages including high expansion potential and extensive differentiation potential [ 6 , 7 ]. (hindawi.com)
There are stem cell clinics in the U.S., but FDA regulations currently don't allow the more advanced treatment protocols we've developed that are backed by more than 20 years of clinical research. (maxim.com)
Today, clinical trials using stem cell-derived dopaminergic progenitors have commenced. (lu.se)
Next, in order to study the potential of autologous cell replacement therapy we transplanted progenitors derived from a PD patient into a pre-clinical rat model. (lu.se)
A potentially pre-clinical aspect of this thesis is detailed in paper №4 where I describe a robust protocol for the generation of functional mesDA neurons from human embryonic stem cells that are functional in a rat model of PD. (lu.se)

Funding for stem cell research in two of the most liberal states in the nation - California and Maryland - appears to be shifting away from embryonic to adult stem cells. (womenofgrace.com)
Over 60 organizations, including the Association of American Universities, wrote to Senate leaders opposing prohibitions or restrictions that would further impede the use of federal funding for fetal tissue or embryonic stem cell research. (aau.edu)
STEM CELL RESEARCH is a very controversial topic in today's time. (ipl.org)
Stem cell research is not worth supporting. (ipl.org)
Advocates of stem cell research believe that the cells are not equivalent to human life because it is inside the womb even facing the fact that the start of a human life is in the moment of conception. (ipl.org)
While many people say the use of the cell research is a way to advance medical knowledge and expand treatments, there is no guarantee that the treatments will work. (ipl.org)
In this article R. Alta Charo states that we have a right to use fetal tissue for research and therapy (Fetal Tissue, 1) The article goes into how a lot of people find this to be a moral issue and a matter of the conscience and explains how the antiabortion activist that don't agree with the research are actually benefitting from the fetal tissue. (ipl.org)
All of this debate raises an important question, Should embryonic stem cell research be conducted for treatment of present and future diseases? (ipl.org)
People who believe that an embryo should not be destroyed tend to say that embryonic stem cell research should not be conducted. (ipl.org)
On the other hand, people who believe that embryonic stem cell research creates means of curing diseases reply that the research should be conducted. (ipl.org)
However, more research is needed to help understand the potential uses of amniotic fluid stem cells. (healthline.com)
From 1999 onwards my research has been focused primarily on osteoblast biology and approaches to tissue engineer and model bone biology, pathology and repair. (nottingham.ac.uk)
My research continues to focus on stem cells and osteoblasts and in particular 3D cell culture models and microenvironments. (nottingham.ac.uk)
My research interests focus mainly on stem cells (embryonic, 'adult' and fetal origins) and their applications in tissue engineering, particularly the osteoblast and bone tissue. (nottingham.ac.uk)
The study was supported by São Paulo Research Foundation - FAPESP , and the results are published in Stem Cell Research & Therapy . (eurekalert.org)
But the story has taken a new twist as religious groups are now beginning to discourage followers from participating -- because ALS research at times relies on embryonic stem cells. (salon.com)
She added that donors "can stipulate where their money goes and can ask that it not pay for embryonic stem cell research. (salon.com)
The Archdiocese suggests people who want to do the challenge contribute to the John Paul II Medical Research Institute, "where the research is only conducted using adult stem cells. (salon.com)
Early polio research included the use of embryonic tissue . (salon.com)
there are reasons to have conversations about embryonic stem cell research and fetal tissue research. (salon.com)
Researchers used stem cells obtained from the embryonic tissue of cynomolgus monkeys, a type of macaque commonly used in genetics research because of their similarity to humans. (planer.com)
So when St. Francis Memorial Hospital in San Francisco announced that the topic of his speech there last week would be "Stem Cell Research: Hope or Hype? (latimes.com)
Skepticism about the potential of stem cell research was wholly absent from the campaign for Proposition 71. (latimes.com)
Gene therapy and monoclonal antibodies didn't arrive with even a fraction of the hype surrounding embryonic stem cell research. (latimes.com)
A bill approved by the Senate yesterday to spur stem cell research would go a long way toward removing restrictions that have slowed progress, burdened laboratories with red tape, reduced American competitiveness and discouraged young researchers from entering the field, several leading stem cell scientists said. (consumerwatchdog.org)
The legislation would end a policy put in place by Mr. Bush that restricts federal financing for human embryonic stem cell research only to cell lines, or colonies, that were derived on or before Aug. 9, 2001, the day the policy was announced. (consumerwatchdog.org)
And over time some of the cells have accumulated genetic abnormalities that make them more difficult to use even for basic research. (consumerwatchdog.org)
Scientists are tenacious and resourceful, so we figure out ways to get our work done regardless," said Dr. Evan Snyder, professor and director of the stem cell program at the Burnham Institute for Medical Research in San Diego. (consumerwatchdog.org)
Alternatively, research using eggs may point the way to methods which mimic their properties using other human cells and chemical agents. (spiked-online.com)
Yet as a new book called The Proteus Effect points out, both types of stem cell research date back half a century. (freerepublic.com)
Research with embryonic stem cells has progressed at snail's pace simply because they are so terribly difficult to work with. (freerepublic.com)
Through medical research, stem cells can now be grown and transformed into a variety of specialised cells with characteristics consistent with tissues such as muscles or nerves. (derstandard.at)
But medical researchers hope to be able to use technologies derived from stem cell research to treat a much wider variety of diseases. (derstandard.at)
Though not intended to be an exhaustive explanation of this important topic, we believe this will help to clarify and explain the questions most frequently asked about embryonic stem cell research. (erlc.com)
Why are stem cells so important to research? (erlc.com)
There are two main reasons stem cells are of interest to both scientific and medical research. (erlc.com)
The Daily Signal ) The Trump administration is investing up to $20 million for the next two years to determine effective alternatives to using tissue from aborted babies for research. (liveaction.org)
The announcement Monday from the Department of Health and Human Services comes after the administration in September terminated a government contract with California-based Advanced Bioscience Resources Inc. to provide human fetal tissue research. (liveaction.org)
This means that we understand and appreciate that medical research and the testing of new medical treatments using fetal tissue raises inherent moral and ethical issues," HHS spokeswoman Caitlin Oakley said in a prepared statement. (liveaction.org)
The NIH will fund research to develop alternative models to the use of human fetal tissue in biomedical research. (liveaction.org)
After a recent review of a contract between Advanced Bioscience Resources Inc. and the Food and Drug Administration to provide human fetal tissue to develop testing protocols, HHS was not sufficiently assured that the contract included the appropriate protections applicable to fetal tissue research or met all other procurement requirements," Oakley said. (liveaction.org)
As a result, HHS is now conducting an audit of all acquisitions involving human fetal tissue to ensure conformity with procurement and human fetal tissue research laws and regulations," she said. (liveaction.org)
The announcement also comes amid blistering attacks from the mainstream media that halting federal funding of fetal tissue research is preventing a study to "discover a cure for HIV. (liveaction.org)
In September, HHS issued a statement announcing an audit would be conducted of all acquisitions involving human fetal tissue to ensure conformity with procurement and human fetal tissue research laws and regulations," Oakley said regarding the San Francisco contract. (liveaction.org)
In addition, HHS has initiated a comprehensive review of all research involving fetal tissue to ensure consistency with statutes and regulations governing such research, and to ensure the adequacy of procedures and oversight of this research in light of the serious considerations involved," Oakley said. (liveaction.org)
Eric Stoffers had already enjoyed success as an entrepreneur before he founded BioXcellerator , a company which is rapidly gaining a global reputation as a leader in stem cell therapy and research. (maxim.com)
That's because the research clearly shows that these cells can significantly improve patient outcomes through safe treatment protocols and are ethically sourced. (maxim.com)
But we do our best to make as much information available as widely as possible because when patients do research stem cell therapy, they discover that these improved outcomes are based on many scientific studies published by accredited academic and research organizations. (maxim.com)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
His main research areas are developmental biology, cell morphogenesis, adult stem cells and cardiac function analysis. (amrita.edu)
The focus of my research is to understand cell fate specification in the developing brain and in human neural progenitor cells using cell-based models of neuronal differentiation. (lu.se)

Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development. (ox.ac.uk)
Mathematical modeling of Hematopoietic Stem Cell and Leukaemic Stem Cell culture systems. (imperial.ac.uk)

Abstract Stem cells constitute the source of cells that replenishes the worn out or damaged cells in our tissue and enable the tissue to carry out the destined function. (techscience.com)

Researchers hope to use these cells to grow healthy tissue to replace injured or diseased tissues in the human body. (medlineplus.gov)
Researchers have identified the first gene linked to the productivity of the stem cells that produce sperm in mammals. (sciencedaily.com)
What researchers are trying to do is unravel the mystery of the adult germ stem cells in male testicles, which are capable of producing an average of 1,500 sperm during every human heartbeat - or an average of 130 million sperm a day. (sciencedaily.com)
But researchers do not know how the germ stem cells "decide" whether to create other germ stem cells or commit to becoming sperm. (sciencedaily.com)
After a series of tests, the researchers concluded that because of the mutation, the cells were more likely to convert from germ stem cells into sperm, than to produce more germ stem cells to keep the process going. (sciencedaily.com)
Using a fluorescent antibody against the PLZF protein, the researchers were able to show directly that PLZF is expressed in the adult germ stem cells. (sciencedaily.com)
The researchers went on to show that another protein, OCT4, which functions to maintain the stem cells in the early embryo and in cultured embryonic stem cells, is also present in the adult germ stem cell. (sciencedaily.com)
Today, the regrowth of Prometheus' liver has become a symbol to medical researchers for the possible renewal of damaged human organs through the use of human stem cells. (derstandard.at)
Using this technique in animals, the researchers have observed an increase in physiological functions such as the cardiac ejection fraction - a measure of the efficacy of the heart's contraction - and an improvement of cardiac chamber volumes following the placement of these tissue structures on the surface of the animal's damaged hearts. (derstandard.at)
The case sent a chill through the scientific community when it came to light 15 years ago and typifies some of the hurdles researchers have faced while trying to bring stem cell therapies to the market. (ibtimes.com)

The findings, which could someday have implications for infertility, contraception, and stem cell transplantation therapy, will be published in the June issue of Nature Genetics. (sciencedaily.com)
as well as diagnostic techniques, drug development and tissue transplantation. (who.int)
The resulting tissue will be an almost exact genetic match to the patient and will therefore not face rejection and transplantation can be made much safer without the need for immune suppression. (spiked-online.com)
But we realized that cell transplantation may not always be suitable for catastrophic events, such as a heart attack in which there is major myocardial damage. (derstandard.at)
These new transplantation systems enhance the viability of cells and stimulate their outward migration so that they can populate and help regenerate injured tissues. (derstandard.at)
In co-culture with human cortical neurons and after transplantation (AT) into human brain tissue resected. (lu.se)
In co-culture with human cortical neurons and after transplantation (AT) into human brain tissue resected from patients with drug-resistant epilepsy, light-activated channelrhodopsin-2 (ChR2) expressing hdINs induced postsynaptic currents in human neurons, strongly suggesting functional efferent synapse formation. (lu.se)
This involves transplantation of developing midbrain cells from aborted fetuses, (the part that form mesDA neurons), into the striatum of a PD patient. (lu.se)
We still do not know what specific factors contribute to the success in transplantation i.e. what cells are responsible for motor recovery? (lu.se)
The aim of this thesis was to understand how particular factors such as neuronal content, placement and cell source, affect functional outcome after transplantation into the rodent brain. (lu.se)

The expression of TIMP-1, TIMP-2 and TIMP-3 was unchanged following stem cells differentiation into neurons and glia. (uea.ac.uk)
In the developing nervous system, sex differences can bias the number or functionality of neurons, glial cells or synapses. (dissertations.se)
Almost 'every other week there's another interesting finding of adult (stem) cells turning into neurons or blood cells or heart muscle cells,' notes molecular biologist Eric Olson at the University of Texas Southwestern Medical Center in Dallas. (freerepublic.com)
Our current focus is to learn how to direct and efficiently drive controlled differentiation of human stem cells into subtype-specific neurons. (lu.se)
Because of this local degeneration of a relatively small population of dopaminergic neurons in the midbrain, PD has been considered an especially interesting candidate for cell-replacement therapy. (lu.se)
First, we utilized single cell sequencing to dissect the differentiation of stem cells to midbrain dopaminergic neurons. (lu.se)
This approach could be potentially applied directly in the brain by targeting resident cells as a source of new neurons. (lu.se)
The first part of the thesis (Paper I, II, III) shows the development and improvement of a hESC-based system of for virus-mediated direct reprogramming of human glial progenitor cells into both induced dopaminergic neurons (iDANs) and GABAergic interneurons. (lu.se)
CRT aims to replace neurons that have degenerated in PD, with donor cells that have the potential to functionally re-integrate into the host circuitry. (lu.se)

Stroke is a severe cerebrovascular disease in which the neuronal tissue and vasculature of the brain undergo ischemia-evoked alterations. (dissertations.se)
Direct neuronal conversion of resident glial cells is advantageous since they are ubiquitously distributed brain cells able to self-renew and replenish their number, making them ideal candidates for endogenous repair. (lu.se)
Through understanding functional recovery in terms of neuronal subtype and connectivity, the work presented in this thesis aims to bring the prospect of CRT closer to the clinic, I also describe the generation of a very promising alternative cell source that could rival fetal tissue. (lu.se)

Likewise, these cells give rise to progenitor cells committed to a particular cell lineage, and play a crucial role in tissue repair and homeostasis. (bvsalud.org)

This co-culture approach also will enable identification of other distinct hESC subpopulations, and selection for these should prove valuable in generating tissue-specific reagents for cell-based therapy. (ca.gov)
California voters received, instead, a TV campaign promising cures tomorrow for a host of diseases, some of which may never respond to stem cell therapy. (latimes.com)
Those older cell lines, because they were grown using animal cells or serum, might not be suitable for use as medical therapy. (consumerwatchdog.org)
Since natural sugars are difficult to manage, the development of proteoglycan mimics could significantly decrease the cost and complexity of tissue engineering and stem cell therapy. (lbl.gov)
however, cell-based therapy has its risks. (techscience.com)
Using a hybrid therapy that incorporates tissue engineering, we seeded a biodegradable mesh with cardiac stem cells. (derstandard.at)
Exploring these opportunities, Eric discovered that although some U.S. clinics offer stem cell therapy, FDA regulations do not allow the most advanced forms of this treatment. (maxim.com)
Word quickly spread about the exceptional results that stem cell therapy delivers in alleviating chronic pain, treating sports & orthopedic injuries and a wide variety of autoimmune and degenerative diseases, and even reducing the impact of aging. (maxim.com)
Maxim interviewed Eric to find out about his company, how stem cell therapy works, why patients travel outside the U.S. for treatment, and what Eric calls his "moonshot" goal to make age 100, "the new 60. (maxim.com)
But stem cell therapy helps heal the body, reduce the impact of aging and enhance overall wellness - and that's what's most exciting to me. (maxim.com)
That's why professional athletes and "weekend warriors" alike seek out stem cell therapy to alleviate chronic pain and help them heal quicker from injuries and training. (maxim.com)
If stem cell therapy offers so much potential, why isn't treatment available in the U.S. (maxim.com)
I'd also like to see more information available online about stem cell therapy. (maxim.com)
The overall aim of this thesis has been to assess the potential of autologous grafting in cell replacement therapy for PD. (lu.se)
One such idea is cell replacement therapy (CRT). (lu.se)

We have a very high level of contribution, with the donor cells forming a big part of the tissues (and) complex structures all over the monkey body. (planer.com)
In his original report, Thompson demonstrated that human embryonic stem cells could be coaxed into developing gut-like structures, bone, cartilage and muscle (1). (spiked-online.com)
Discuss the importance of mimicking structures of tissues and organs. (manchester.ac.uk)
George D. Snell of The Jackson Laboratory won the 1980 Nobel Prize in Physiology or Medicine for "discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions. (jax.org)

I returned full time to Imperial College in 1999 to take up a lectureship in cell biology and tissue engineering and was also actively involved in establishing the Tissue Engineering Centre. (nottingham.ac.uk)
I cover mainly cell biology and physiology. (nottingham.ac.uk)
Ewen Callaway investigates a new field in cell biology. (nature.com)
NIH on Monday released a notice of intent to publish new funding opportunity announcements inviting applications to develop and refine human tissue models that can be used to accurately model embryonic development or other aspects of human biology but do not rely on the use of fetal tissue obtained from elective abortions. (liveaction.org)
General basics of molecular cell biology are also taught, especially in the first part, while the second part focuses on translational aspects. (tum.de)
2) Textbook of Molecular Cell Biology, Alberts et al. (tum.de)
Dr. Rajaguru Aradhya and Jagla, K., "Insulin-dependent Non-canonical Activation of Notch in Drosophila: A Story of Notch-Induced Muscle Stem Cell Proliferation", in Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling, vol. 1227, J. Reichrath and Reichrath, S., Eds. (amrita.edu)
My group works with translational stem cell biology. (lu.se)
However, further studies are required to gain complete understanding of stem cell biology, which is fundamental for the development of successful cell-based therapies 1-3 . (bvsalud.org)

The workings of stem cells within the testicles are not well understood in mammals, though a few genes have been linked to stem cell self-renewal in the fruit fly, which has a simpler anatomical structure. (sciencedaily.com)
A chimeric monkey has been created using embryonic stem cells with two different sets of genes, a new study has demonstrated. (planer.com)
Alternatively, transgenesis and gene targeting techniques can be used to introduce the patient's genes into the stem cell line. (spiked-online.com)
Safeguards, such as suicide genes to destroy implanted tissue, will have to be considered. (spiked-online.com)
After cloning the antibody genes into an expression vector, this is then transfected into an appropriate host cell line for antibody expression. (cellsignal.com)
In addition, their osteogenic differentiation potential was increased, and genes involved in cell adhesion, FGF-2 signalling, cell cycle, stemness, cell differentiation, and cell proliferation were upregulated, compared to that of the MSCs cultured on uncoated plates. (hindawi.com)
Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
However, when applying this concept to genomes of multicellular organisms such as mammals, one has to deal with a large number of false positive predictions since many transcription factor genes are only expressed in specific tissues or cell types. (lu.se)
We developed TS-REX, a database/software system that supports the analysis of tissue and cell type-specific transcription factor-gene networks based on expressed sequence tag abundance of transcription factor-encoding genes in UniGene EST libraries. (lu.se)
Methods: We analysed methylation status of 807 cancer-related genes in 189 fresh frozen primary breast tumours and four normal breast tissue samples using an array-based methylation assay. (lu.se)

Technically, manufacturers are required to submit stem cell therapies for review as a drug, and to provide evidence of their safety and efficacy, but the U.S. Food and Drug Administration hasn't enforced the rule consistently. (truthdig.com)
Stem cell therapies already exist in medical practice. (derstandard.at)
The data presented in this thesis may serve as valuable resources to help optimize future cell replacement therapies for patients suffering from PD. (lu.se)

Blastocytes obtained through nuclear transfers would be used to generate the embryonic stem cells that could be differentiated to specific tissues or organs for transfer to the nuclear donor. (spiked-online.com)
It's well established that embryonic stem cells can generate any kind of tissue found in the body,' Mooney writes flatly. (freerepublic.com)
But we already know embryonic cells cannot generate placental tissue . (freerepublic.com)
that is, they have the ability to generate other stem cells and perpetuate themselves. (bvsalud.org)

Notch receptors and Notch ligands were detected in virtually all cells throughout EB development. (karger.com)
Since positional information plays an important role in the embryonic development of several tissue systems, we tested whether AGM HSC induction is influenced by the surrounding dorsal and ventral tissues. (ox.ac.uk)
Growth factors guide the development of embryonic stem cells but often require proteoglycans - surface-bound sugar - to interact with the cell. (lbl.gov)
Liver injury can cause steatosis and inflammation, and further activation of hepatic stellate cells (HSCs) often leads to the development of nonalcoholic liver fibrosis. (techscience.com)
Traditional polyclonal and monoclonal antibodies are the product of normal B cell development and genetic recombination. (cellsignal.com)
All specialized cells arise originally from stem cells, and ultimately form a small number of embryonic cells that appear during the first few days of development. (erlc.com)
We develop novel single-cell genomic technologies and apply them to better understand lung development and disease. (bio5.org)
The molecular study of fat cell development in the human body is essential for our understanding of obesity and related diseases. (mdpi.com)
Human cortical organoids (hCOs), derived from human embryonic stem cells (hESCs), provide a platform to study human brain development and diseases in complex three-dimensional tissue. (nih.gov)
The development and progression of tumors is taught on a molecular genetic and cell biological basis. (tum.de)
Neuroscience focusing on human development and disease has long been hampered due to ethical rea¬sons, low tissue availability, and low translatability from animal models. (lu.se)

Cord blood stem cells are harvested from the umbilical cord after childbirth. (healthline.com)
A tiny vial no larger than the palm of his hand, he told the group, contains roughly 10 million live stem cells, harvested from the placenta, amniotic fluid, umbilical cord or amnion, the membrane that surrounds the fetus in the womb. (truthdig.com)
Adult stem cells come from all over the body, plus umbilical cords and placentas. (freerepublic.com)
Groopman specifically mentions Fanconi's Anemia, but it was first treated with umbilical cord stem cells 16 years ago. (freerepublic.com)
Several technologies have been described over the past 10 years to create functional heart tissue by using stem cells that have been isolated from other tissues such as bone marrow, skeletal muscle, and umbilical cord blood. (derstandard.at)

Cytopathology of bone and soft tissue tumors. (wikipedia.org)
Many clinics offer stem cells taken from a patient's own bone marrow or fat. (truthdig.com)
MSCs can easily be obtained from various human tissue sources such as the bone marrow, cord blood, placenta, and adipose [ 2 - 5 ]. (hindawi.com)
Such cells exist in the crypts of the intestine, in the basal layer of the skin epithelium, in the bone marrow (hematopoietic cells). (vechnayamolodost.ru)
We're actually developing products now," said Timothy Mayleben, chief executive of Aastrom, which is using cells derived from a patient's own bone marrow to develop treatments for cardiovascular disease. (ibtimes.com)

Neurodegeneration and neurodegenerative diseases (including the shared mechanisms of nerve cell death that contribute to many diseases), Vascular Cognitive Impairment and Dementia (VCID), NINDS tissue/cell resources, basic invertebrate neuromuscular junction (NMJ). (nih.gov)
While at the hospital she was unaware that the doctors there were experimenting on her taking cell samples from her body, to help find a resolution to multiple diseases. (ipl.org)
Since stem cells have the ability to turn into various other types of cells, scientists believe that they can be useful for treating and understanding diseases. (healthline.com)
My PhD focussed on investigating the distributions and possible functions of nitric oxide/nitric oxide synthases in the physiology and pathology of a variety of tissues and organs and I was fortunate enough to publish some of the first papers on the involvement of these molecules in human diseases, notably in the cardiovascular system. (nottingham.ac.uk)
Ironically, some of the very diseases he says embryonic stem cells may conquer have long been treated with adult stem cells. (freerepublic.com)
So when Groopman says adult marrow cells may not be 'fully optimal as treatment for many fatal diseases,' he's ignoring at least 13 other adult stem cells that could be. (freerepublic.com)
In recent years, molecular mechanisms of cell aging, their connection with oncological diseases and inflammation have been discovered. (vechnayamolodost.ru)
Symptoms and Signs Amyotrophic lateral sclerosis and other motor neuron diseases are characterized by steady, relentless, progressive degeneration of corticospinal tracts, anterior horn cells, bulbar motor nuclei. (msdmanuals.com)

Nor are they sure how well a patient's body will accept stem cell treatments derived from cells donated by a stranger, or whether the growth of implanted cells can be managed. (latimes.com)
The cost of surgery and the time of hospitalization would be reduced, and the standard use of life-long immune suppression medications would be unnecessary in the case of an engineered myocardium using a patient's own tissue. (derstandard.at)

Thus, understanding the molecular events driving the successful differentiation of stem cells into several lineages is essential for its better manipulation of human applications. (techscience.com)

But the benefits using these types of stem cells have ranged from marginal, to transient, to nil. (derstandard.at)
These cancers originate from cells of the sympathetic nervous system (SNS), in turn derived from the transient embryonic neural crest stem cell population. (lu.se)

These cells have been successfully used to treat children with blood cancers, such as leukemia, and certain genetic blood disorders. (healthline.com)
Cloning describes the processes used to create an exact genetic replica of another cell, tissue or organism. (medlineplus.gov)
Pinning proteins to its genetic material at the height of inflammation, the cells bookmark where they left off in their last tussle. (scitechdaily.com)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
Banking of multiple cell lines with varying genetic spectrum that can be matched to patients is one possibility. (spiked-online.com)
Here, the stem cell line is created using the genetic properties of the prospective recipient via somatic cell nuclear transfer. (spiked-online.com)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)

Chimeric explant cultures with genetically distinguishable AGM and ventral tissues show that the increase in HSC activity is not from ventral tissue-derived HSCs, precursors or primordial germ cells (as was previously suggested). (ox.ac.uk)
To create iPSCs, scientists genetically reprogram the adult stem cells so they behave like embryonic stem cells. (healthline.com)
It might also allow replacement tissues to be made that are genetically matched to a patient, so they would not be rejected when implanted. (consumerwatchdog.org)

At these sites, which are a compound of stromal cells, extracellular matrix and soluble factors, complex molecular interactions that maintain the essential properties of stem cells occur, such as self-renewal and differentiation into multiple lineages, according to the organism's needs. (bvsalud.org)

The proteoglycan mimic facilitated this interaction and allowed the stem cells to develop into neural rosettes, which are precursors to nerve cells. (lbl.gov)

Use of human fetal tissue raises several ethical issues, but are there alternative cell sources that can substitute effectively? (lu.se)

Scientists at Stanford University in California have been able to coax embryonic stem cells into becoming eggs and sperm, which could one day lead to the creation of children through entirely artificial means. (womenofgrace.com)
British scientists are hailing the recent creation of human sperm cells that they believe could revolutionize fertility treatment. (womenofgrace.com)
Scientists are hoping that the cells can be made from someone's own skin to treat a disease. (healthline.com)
This may allow scientists to culture healthy tissue cells in the lab to replace damaged ones in the human body. (latimes.com)
Scientists have long suspected that even cells that are not traditionally involved in the immune response have the rudimentary ability to remember prior insults and learn from experience. (scitechdaily.com)
That would free scientists to use federal money to do experiments with many of the scores of stem cell lines that have been derived since then either in other countries or with private money in the United States. (consumerwatchdog.org)
Scientists have been able to derive and work with newer cell lines, but only by using private or state money. (consumerwatchdog.org)
The exact process of differentiation is not yet understood and although embryonic stem cells can, in principle, provide for all human tissue, scientists are some way from controlling the process. (spiked-online.com)
It might be expected that the richest nation on Earth would encourage its top scientists to pursue this work with vigor rather than limiting funding opportunities, creating legal barriers and fencing off any newly developed cell lines. (spiked-online.com)
Scientists have already discovered at least 14 different types of adult stem cells. (freerepublic.com)

Isoform 1 is expressed in all tissues except brain, skeletal muscle and PBMC, 3 is ubiquitous, 4 is expresed in all tissues except brain, skeletal muscle, lung and prostate and 5 is detectable only in testis and at very low level in brain and prostate. (lu.se)

The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)

That life may not even be worth it because it takes multiple tries before the stem cells are even suitable for use in medical treatments. (ipl.org)
Hall says he believes that a crucial part of the stem cell agency's mission is public education, including admonitions that the journey from today's knowledge to clinically effective treatments is "a long, hard road. (latimes.com)
Alongside scientifically proven treatments, an industry has sprung up in which clinics offer miracle remedies from stem cell products. (truthdig.com)
In contrast, the number of treatments using embryonic stem cells is zero. (freerepublic.com)

We generated light-sensitive human embryonic stem cell (hESC)-derived GABAergic interneurons (hdIN) and tested their functionality. (lu.se)

Chimerism is a phenomenon where an organism features two or more sets of cells with different genomes. (planer.com)
There was no evidence that the aging of individual cells plays an important role in the aging of the whole organism. (vechnayamolodost.ru)
Before Hayflick's discovery, the prevailing view was that cells are immortal, and aging and death are a property of the organism as a whole. (vechnayamolodost.ru)

While polyclonal antibodies are secreted by many different B cell clones and recognize multiple antigenic epitopes, monoclonals originate from a single B cell clone and are specific for just one epitope. (cellsignal.com)

There are several types of stem cells that can be used for different purposes. (healthline.com)
Introduce students to various types of stem cells, their differentiation capabilities and their potential applications. (manchester.ac.uk)

This cell is called a zygote, or a fertilized egg. (healthline.com)
The zygote divides into two cells, then four cells, and so on. (healthline.com)

Conserved molecular portraits of bovine and human blastocysts as a consequence of the transition from maternal to embryonic control of gene expression. (mpg.de)
But the molecular mechanism that explained this process, and how the cell could use it to respond to types of inflammation and injury that it had never seen before, remained a mystery. (scitechdaily.com)
Users of the Molecular Foundry created a mimic of proteoglycans - surface-bound sugars - that are critical in the differentiation of embryonic stem cells into neural cells. (lbl.gov)

Anatomy51

Organisms11

Diseases5

Chemicals and Drugs71

Analytical, Diagnostic and Therapeutic Techniques and Equipment55

Psychiatry and Psychology1

Phenomena and Processes62

Disciplines and Occupations5

Technology, Industry, Agriculture1

Humanities1

Information Science2

Vitro17

Pluripotent15

Emerged about embryonic stem cel1

Embryos12

Mesenchymal5

Differentiate15

Regenerative9

ESCs11

Transplants4

Mouse embryonic5

Parkinson's7

Therapeutic7

Tumor5

Organs and tissues4

Mice6

Adult stem8

Different tissues2

Regeneration5

Cardiomyocytes1

Clinical9

Research51

Hematopoietic stem2

Abstract1

Researchers10

Transplantation10

Neurons9

Neuronal3

Progenitor cells1

Therapy15

Structures4

Biology9

Genes11

Therapies3

Generate4

Development11

Umbilical5

Bone5

Diseases8

Patient's2

Differentiation of stem cells1

Transient2

Genetic8

Genetically3

Self-renewal and differentiation1

Precursors1

Fetal tissue raises1

Scientists10

Skeletal muscle1

Somatic1

Treatments4

HESC1

Organism3

Clones1

Types of stem cells2

Zygote2

Molecular3