• Senescent cells are characterized by an upregulation of proinflammatory cytokines, which is termed the senescence-associated secretory phenotype (SASP). (nature.com)
  • Senescent cells cause harm through what is known as the senescence-associated secretory phenotype (SASP) , the secretion of signals that spur inflammation, tissue modeling, and alterations in cellular behavior. (fightaging.org)
  • The gastric chief cell also contains many large secretory vesicles filled with digestive enzymes in the apical cytoplasm. (wikipedia.org)
  • After intracellular conversion into 11 C-serotonin and uptake into secretory vesicles by vesicular monoamine transporter 2 or biodegradation by monoamine oxidase A (MAO-A) into 11 C-5-hydroxyindoleacetic acid ( 11 C-HIAA), the tracer is rapidly excreted into the urine. (snmjournals.org)
  • CHL1 expression was found to correlate positively with insulin secretory index, GLP1R but inversely with HbA 1c and BMI. (lu.se)
  • [ 16 ] Potential mechanisms through which TCF7L2 variants influence T2DM include its role in adipogenesis, myogenesis, and pancreatic islet development, as well as in beta-cell survival and insulin secretory granule function. (medscape.com)
  • This phenotype is associated with increased subcutaneous adipose tissue mass, adipocyte hypertrophy, and inflammation. (medscape.com)
  • RNA sequencing data revealed a high expression of CHL1 in pancreatic islets and adipose tissues compared to liver and muscles tissues. (lu.se)
  • lower blood glucose, higher glucose utilization in tissues, higher glycogen synthesis, lower gluconeo-genesis, lower release of fatty acids from adipose tissues, and higher protein sysnthesis. (medium.com)
  • For the present proposal we will test the hypothesis, that adipose tissue is one of the links between systemic inflammation causing insulin resistance in critically ill patients and low-grade inflammation causing insulin resistance in obesity. (europa.eu)
  • In gastric tissue, a loss of parietal cells due to chronic inflammation has been shown to affect chief cell differentiation and can induce chief cells to transdifferentiate back into neck cells and can lead to the formation of mucus cell metaplasia known as spasmolytic polypeptide expressing metaplasia (SPEM) that could be precancerous. (wikipedia.org)
  • Cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) can be generated by inflammatory and nonimmune cells in response to inflammation, tissue injury, microbial invasion, and immunological reactions ( Dinarello, 1994 ). (jneurosci.org)
  • When the food antigen load surpasses the body's ability to clear the food immune complexes from the circulation, tissue deposition, complement activation, and secretory inflammation of the ear, nose and throat occur. (healthy.net)
  • COPD is characterised by tissue destruction and inflammation. (bmj.com)
  • Recent studies have indicated that adipose tissue plays a major role in the secretion of inflammatory factors, which have been called adipo-cytokines or adipokines. (europa.eu)
  • Senescent cells in aging tissues are characterized by increased inflammatory cytokine and growth factor secretion. (jax.org)
  • From birth to approximately 3 months , the mammary gland grows at roughly the same rate as the rest of the body (isometric growth). (grobernutrition.com)
  • From 3 months until approximately 10 months of age, the mammary gland develops at a faster rate than the body (allometric), contributes a large portion of the ductwork development and increases the size of the fat pad. (grobernutrition.com)
  • In the mammary gland, secretory epithelial cells are removed by apoptosis during involution. (brighton.ac.uk)
  • Groups A and B intervened with BA showed significant higher level of TBA in both maternal and fetal serum, more mortality rate of fetal rats, more concentration of SP-A in fetal serum, and wider alveolus mesenchyme of fetal rats than the control Group C. Higher level of BA associated with increased fetal risk and lower numerical density of mitochondria in type II alveolar epithelial cells. (hindawi.com)
  • The 273-gene signature was validated as cancer-associated genes by matching this set to additional independent tumor tissue samples from 163 patients with HCC, 56 patients with lung carcinoma, and 38 patients with breast carcinoma. (okstate.edu)
  • From this signature, 30 genes were altered most significantly in tissue samples from high-risk individuals with cirrhosis and from patients with HCC. (okstate.edu)
  • Among them, 12 genes encoded secretory proteins found in sera. (okstate.edu)
  • These different genes produce pheochromocytomas with different ages of onset, secretory profiles, locations, and potential for malignancy. (medscape.com)
  • Following irradiation, SFR decreased while senescence-associated β-galactosidase-positive cells (via immunofluorescences) and senescence-related genes and secretory-phenotypes (e.g., p21 and MMP3 in qRT-PCR) increased. (lu.se)
  • SFR was unchanged following EVs treatment, but senescence-associated genes and secretory-phenotypes decreased. (lu.se)
  • Here, we show that nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the NAD + salvage pathway, governs the proinflammatory SASP independent of senescence-associated growth arrest. (nature.com)
  • The salivary gland is critical to the biological success of ticks indicating it may hold potential as a target tissue for acaricides. (phys.org)
  • Salivary gland function was evaluated 18 days after irradiation using salivary gland flow rate (SFR), gene expression (by qRT-PCR) and histopathology. (lu.se)
  • At the same time, we developed a sustainable histology process to reduce xylene utilization in histological processing for salivary gland tissue processing. (lu.se)
  • Normal body tissues and organs are attacked, causing the multiple autoimmune disorders that develop in people with IPEX syndrome. (medlineplus.gov)
  • Postnatal stem cells have been sourced from umbilical cord blood, umbilical cord, bone marrow, peripheral blood, body fat, and almost all body tissues, including the pulp tissue of teeth 8 . (bvsalud.org)
  • Also, the increased production rate of cytokines such as IL-6 or TNF-alpha has been implicated in the pathogenesis of car diovascular complications and insulin resistance. (europa.eu)
  • Salivary duct cells also produce cytokines, eventually damaging the secretory ducts. (msdmanuals.com)
  • Throughout this period, the cells incorporate linearly [ 3 H]leucine into protein for up to 4 h at a rate 90% greater than hemipituitaries, and they synthesize, transport intracellularly, and release the two major pituitary secretory products, growth hormone and prolactin. (rupress.org)
  • The requirement for a high-energy diet, to achieve the target growth rate of high genetic merit heifers, must be balanced with sufficient protein, and in particular, high quality by-pass protein. (grobernutrition.com)
  • The dataset contains over 1.92 million data points in protein isotope labeling kinetics, culminating as the in vivo turnover rates of 3,228 cardiac proteins and the expression levels of 8,064 proteins. (nature.com)
  • The present dataset was collected using a technology platform we recently developed, which overcame several technical challenges in quantifying individual protein turnover rates on a proteome scale. (nature.com)
  • In contrast to steady-state protein abundance, which may be quantified directly in mass spectrometry (MS) by spectral intensity 16 , 17 or sampling frequency 18 , 19 , protein turnover rates cannot be predicted from steady-state data 20 , requiring instead methods that can distinguish old and new protein molecules in mass spectra 11 , 21 . (nature.com)
  • The high-affinity folate binding protein (FBP) exists in humans in four isoforms, folate receptors (FRα and FRβ, or FOLR1 and FOLR2) that are attached to the outer cell surface by glycosyl-phosphatidyl-inositol (GPI) link, and FRγ (FOLR3) that is a secretory protein, and expressed at much lower levels than FRα and FRβ. (turkupetcentre.net)
  • Cortisol promotes hepatic protein synthesis and gluconeogenesis, and stimulates release of fatty acids from adipose tissue by maintaining the synthesis of hormone sensitive lipase. (medium.com)
  • The local action of these released peptides are known to increase tissue blood flow, capillary permeability, and inflammatory cell activities ( Holzer, 1988 ). (jneurosci.org)
  • On infusion, culture-expanded MSCs regulate inflammatory and immune responses and tissue repair. (bmj.com)
  • OBJECTIVE: To evaluate the efficacy of oral administration of a novel composition composed of Quercetin, Curcumin, Acetylcysteine in reducing pain in women affected by endometriosis, through the reduction of the inflammatory-hyperproliferative component of the ectopic endometrial tissue. (endometriosistreatmentreport.com)
  • Recently, bile acid was found to cause surfactant inactivation by enhancing the activity of secretory phospholipase A2 (sPLA2) and induce inflammatory response of fetal lung [ 5 , 8 ]. (hindawi.com)
  • The gastrointestinal (GI) epithelium is a highly regenerative tissue with the potential to provide a renewable source of insulin+ cells after undergoing cellular reprogramming. (diabetesresearchconnection.org)
  • 3 4 Since then, it has become evident that MSCs reside in many tissues, including mesenchymal tissues (bone, adipose tissue, connective tissue), umbilical cord and several organs including the liver, spleen and lung. (bmj.com)
  • This high rate of turnover is a protective mechanism designed to protect the epithelial lining of the stomach from both the proteolytic action of pepsin and the acid produced by parietal cells. (wikipedia.org)
  • Even a small number of senescent cells, say 1% of the cells in an organ, can alter tissue structure and the behavior of normal cells to a great enough degree to produce disease symptoms. (fightaging.org)
  • Reprogramming of antral stomach cells assembled into bioengineered mini-organs in vitro yielded transplantable units that also suppressed hyperglycemia in diabetic mice, highlighting the potential for development of engineered stomach tissues as a renewable source of functional β cells for glycemic control. (diabetesresearchconnection.org)
  • The gastrointestinal (GI) tissues are potential sources for such continued generation of β cells. (diabetesresearchconnection.org)
  • We sought to devise improved strategies to derive functional insulin-secreting (insulin+) cells from GI tissues and to harness the regenerative capacity of these tissues as a renewable source of β cells. (diabetesresearchconnection.org)
  • A new procedure has been developed for dissociating anterior pituitary tissue and producing a viable suspension of single cells. (rupress.org)
  • By electron microscopy five types of secretory cells (somatotrophs, mammotrophs, thyrotrophs, gonadotrophs, and corticotrophs) plus endothelial and follicular cells can be identified and are morphologically well preserved up to 20 h after dissociation. (rupress.org)
  • These effects were partially mediated through enhanced TGF-β signaling, which contributes to tissue fibrosis and epithelial-mesenchymal transition (EMT) of tumor cells. (jci.org)
  • Together, these results suggest that senescent cells accelerate and improve tissue repair. (jax.org)
  • Scar tissue (stained for collagen, in orange) is evident in healed wounds from transgenic p16-3MR mice lacking senescent cells (bottom panel, GCV-treated) compared to control mice (top panel, PBS-treated). (jax.org)
  • A function-blocking anti-b1 integrin antibody doubled the rate of apoptosis in single cells cultured with basement membrane, indicating that integrin-mediated signals contributed to survival. (brighton.ac.uk)
  • We suggest that an analysis of the apoptotic rate induced by serum in Jurkat cells and the levels of soluble CD95 in serum could be helpful during the prognosis and treatment of women detected with precancerous lesions or cervical cancer. (pdgfreceptor.com)
  • In vitro cell culture and animal studies have demonstrated that mesenchymal stromal cells (MSCs) have the capacity to modify immune responses and to enhance tissue repair. (bmj.com)
  • Characteristics influencing the grading of a tumor include the cell subtype (as described above), the rate at which the tumor cells are multiplying and the tumor is growing (cell proliferation and mitotic index are terms that express this concept) and the degree of brain invasion by the tumor. (brainsciencefoundation.org)
  • These tumors exhibit slow growth and very little multiplication of cells and very rarely invade the brain tissue. (brainsciencefoundation.org)
  • Cortisol maintains tissue responsiveness to catecholamines, and stimulates a-adrenegic receptor function and receptors in vascular smooth muscle and nerve cells. (medium.com)
  • The key elements of tissue engineering are stem cells, morphogen, and a scaffold of extracellular matrix. (bvsalud.org)
  • All tissues originate from stem cells. (bvsalud.org)
  • A stem cell is commonly defined as a cell that has the ability to continuously divide and produce progeny cells that differentiate (develop) into various other types of cells or tissues. (bvsalud.org)
  • These dental stem cells are considered mesenchymal stem cells (MSCs) and possess different levels of capacities to become specific tissue forming cells. (bvsalud.org)
  • Cortisol promotes conservation of glucose to maintain the activity of glyconeogenic enzymes in the liver, and inhibits glucose utilization in the peripheral tissues. (medium.com)
  • For instance, the increase of GH levels is responsible for insulin resistance in the liver and other peripheral tissues, leading to impaired glucose tolerance or overt diabetes mellitus. (medscape.com)
  • 13. Epinephrine and, to a suf cient control over its uni- formance, such that many of the sensitive erotic tissue of rats nesc injection to combat racism and (hetero)sexism operate through social interactions between spermatozoa static secretions (eps), secretory damage of the. (ben.edu)
  • Multidrug resistance-associated proteins (MRPs) and organic anion transporters (OATs) transport folates in addition to many other substrates, mostly in epithelial tissues. (turkupetcentre.net)
  • GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. (thermofisher.com)
  • Collagen VI (COL6) is highly expressed in adipose tissue, upregulated in the obese state, and enriched in breast cancer lesions and is a stimulator of mammary tumor growth. (jci.org)
  • The correct type of extracellular matrix was required, since only a basement membrane, not plastic or a collagen I matrix, lowered the rate of apoptosis. (brighton.ac.uk)
  • 11 12 MSCs furthermore contribute to tissue homeostasis through anti-apoptotic and regenerative properties. (bmj.com)
  • Although current treatment modalities offer high levels of success for many conditions, an ideal form of therapy might consist of regenerative approaches in which diseased or necrotic pulp tissues are removed and replaced with healthy pulp tissue to revitalize teeth. (bvsalud.org)
  • One novel approach to restore tooth structure is based on regenerative endodontic procedures by application of tissue engineering. (bvsalud.org)
  • Subsequent regenerative dental procedures include the development of guided tissue or bone regeneration (GTR, GBR) procedures and distraction osteogenesis 2 the application of platelet rich plasma (PRP) for bone augmentation 17 . (bvsalud.org)
  • The purpose of this article is to review the biological principles of tissue engineering and the hurdles that must be overcome to develop regenerative endodontic procedures. (bvsalud.org)
  • Interestingly, MSCs showed enhanced glycolysis during challenge with cPE, but no significant changes in oxygen consumption rates (OCR). (stanford.edu)
  • Interestingly, similar secretory responses occur during tissue injury. (jax.org)
  • Interestingly, PDGF-AA applied topically to GCV-treated mice increased myofibroblast numbers and rescued wound closure rates. (jax.org)
  • Newer induction immunosuppressive agent combinations [T-cell-depleting antibody (anti-CD3 antibody, alemtuzumab, or antithymocyte globulin) and a tumor necrosis factor alpha (TNF- α ) inhibitor (etanercept or infliximab)] have improved long-term diabetes reversal rates (~50% in 5 years at the most experienced centers) [ 9 ], presumably by preserving transplanted β -cell mass. (hindawi.com)
  • Public reversal rates remains lower than that found in negative feedback on ef cacy outcome during multi- institutional in-of ce dose titration clinical trials in 21 different centers. (ben.edu)
  • A cancer that begins in the bone and soft tissue. (rozlytrek.com)
  • The dose deposition profile of protons in the form of a "Bragg peak" imparts a unique normal tissue sparing ability [ 6 ] while depositing maximal dose within tumours [ 4 , 7 ]. (frontiersin.org)
  • This encompasses both deposition, which is the process of removing particles in various regions of the respiratory tract during the breathing of particle-laden air, and clearance, which refers to the rates and routes by which deposited parti- cles are removed from the respiratory tract. (cdc.gov)
  • Chronic exposures result in respiratory tract burdens that continue to increase over time until the rate of deposition is offset by the rate of clearance, thereby resulting in a steady-state burden from that time on. (cdc.gov)
  • The islets of Langerhans are the major constituent of the neuroendocrine pancreas, and neuronal tissue makes up the remaining part. (snmjournals.org)
  • Uptake of 11 C-5-HTP in the normal human pancreas is generally high, but this has not previously been systematically investigated despite the fact that islets and some neuronal tissue constitute the only amine precursor uptake and decarboxylase tissue within the pancreas. (snmjournals.org)
  • These histological subtypes are organized into three grades that generally reflects the rate of growth and likelihood of recurrence based on cytological features. (aans.org)
  • Antibiotics increase the recurrence rate of otitis media. (healthy.net)
  • The main criticism implantation rate or recurrence, maintenance of libido is related to erectile dys- patients with generalized anxiety disorder. (ben.edu)
  • WHO graded each of these meningioma subtypes into one of three categories based primarily upon the likelihood of recurrence and the rate of growth exhibited by each. (brainsciencefoundation.org)
  • A higher tumor grade is associated with a greater likelihood of the tumor's recurrence and/or faster growth rate and increased potential of brain invasion (often referred to as more aggressive behavior). (brainsciencefoundation.org)
  • Atypical meningiomas (WHO grade II, which account for 18% of meningioma cases) exhibit increased tissue and cell abnormalities. (aans.org)
  • Malignant meningiomas (WHO grade III) show increased cellular abnormalities and grow at a faster rate than benign and atypical meningiomas. (aans.org)
  • Atypical meningiomas represent approximately 7-8% of meningiomas and exhibit increased tissue and cell abnormalities. (brainsciencefoundation.org)
  • These tumors show increased cellular abnormalities as well as a faster growth rate compared to benign and atypical meningiomas. (brainsciencefoundation.org)
  • One pathologist might look at the tissue and decide that it is a type of meningioma that falls into the atypical, Grade II category, while a different pathologist may look at the same tissue and decide that the meningioma should be classified as a subtype that falls into the benign, Grade I category. (brainsciencefoundation.org)
  • In conclusion, we identified a unique gene signature in the tissue samples of patients with cirrhosis, which may be used as candidate markers for diagnosing the early onset of HCC in high-risk populations and may guide new strategies for chemoprevention. (okstate.edu)
  • However, the metabolic role and possible consequences of adipose tissue as a secretory organ in critically ill patients has not been investigated to date. (europa.eu)
  • To test this obesity we will characterize adipose tissue as a secretory organ using interstitial fluid sampling techniques and advanced peptide analysis in critically ill patients and healthy controls. (europa.eu)
  • SYN: natural i., nonspecific i.. local i. a natural or acquired i. to certain infectious agents, as manifested by an organ or a tissue, as a whole or in part. (theodora.com)
  • We found that low vinculin (VCL) and cortactin (CTTN) mRNA expression predicts favorable survival rates and has diagnostic value to discriminate between Tz-sensible and Tz-resistant HER2+ BC patients. (bvsalud.org)
  • These terminals transduce thermal, mechanical, and chemical stimuli such that the rate of axon discharge is increased as a function of stimulus intensity. (jneurosci.org)
  • On the one hand, senescence is thought to protect tissues from potentially oncogenic stimuli such as DNA damage. (jax.org)
  • These tumors grow at a faster rate than benign meningiomas and are often characterized by brain invasion. (aans.org)
  • These tumors exhibit a faster growth rate than benign meningiomas and, on occasion, some degree of brain invasion. (brainsciencefoundation.org)
  • However, the immune system can malfunction and attack the body's own tissues and organs instead, which is known as autoimmunity. (medlineplus.gov)
  • Folate receptors FRα and FRβ bind folate and its reduced forms, and are important in folate tissue uptake, and FRα especially in renal reabsorption. (turkupetcentre.net)
  • Less completely secretory prepared by the grass-tree of the respiration. (cultruta.com)
  • We found reduced basal, maximal and ATP-production coupled respiration rates, and decreased proton leak in Mφ during challenge with cPE. (stanford.edu)
  • Accordingly, pregnancy success rates currently achieved by natural or assisted conception for women at high-risk for EPL or RPL can only be increased by an improved understanding of the cellular and molecular mechanisms that control endometrial function during the periimplantation period. (frontiersin.org)
  • However, the risk of exposure of the surrounding normal tissues remains a concern for patient outcomes [ 2 ], with the potential for late tissue damage and escalating the risk of initiating secondary cancers in a patient's lifetime, especially for paediatric patients [ 3 ]. (frontiersin.org)
  • B, manded that a portion and spinal marrow the tissue-elements themselves up the wounds. (cultruta.com)
  • Apoptosis is an active mechanism of cell death required for normal tissue homeostasis. (brighton.ac.uk)
  • Recent studies show that normal tissue sparing can be further enhanced through proton delivery at 100 Gy/s and above, in the so-called FLASH regime. (frontiersin.org)
  • With recent technological advances, modalities such as Intensity Modulated Radiotherapy (IMRT), Stereotactic Body Radiotherapy (SBRT) or Volumetric Modulated Arc Therapy (VMAT) can conform doses to tumours more precisely than possible a few decades ago sparing the normal tissue to a larger extent. (frontiersin.org)
  • Due to this higher normal tissue sparing effect relative to any of the photon based modalities, proton therapy has drawn an increasing interest with globally over 150 proton therapy centres being operational and under construction or at the planning stage [ 8 ]. (frontiersin.org)
  • Langer and Vacanti 19 defined tissue engineering as an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function. (bvsalud.org)
  • The estradiol/progesterone ratio plays crucial role in increasing implantation rate. (gremjournal.com)
  • it is expressed ubiquitously in mammalian tissues, including intestinal and colonic epithelia, basolateral membrane of renal proximal tubules, and blood-brain barrier , and although usually it is considered to be a facilitative transporter, in case of negatively charged folates it can work strongly against concentration gradient. (turkupetcentre.net)
  • Increased numbers of highly fucosylated Haptoglobin alpha isoforms in ascitic fluids and the presence of fucosylated Haptoglobin in tumor tissues of ovarian cancer Mexican patients associated with advanced stages of the disease, reinforce the potential of fucosylated Haptoglobin alpha isoforms to be characterized as biomarkers for disease progression. (biomedcentral.com)
  • Similarly, Seahorse XF Glycolytic Rate Assay Kit was used to detect the extracellular acidification rate (ECAR) and Seahorse XF Real-Time ATP Rate Assay kit was used to detect the real-time ATP production rates from OXPHOS and glycolysis. (stanford.edu)
  • Cell viability, apoptosis, and proliferation rate were not affected. (lu.se)
  • Cellular senescence is a stable growth arrest that is implicated in tissue ageing and cancer. (nature.com)
  • Thyroid hormones influence general tissue growth as well as tubular functions, electrolyte handling and neural input. (avmi.net)
  • From 10 months to calving, the mammary growth slows to a rate more consistent with body growth. (grobernutrition.com)
  • A large amount (80%) of mammary growth occurs during gestation with most of the milk secretory tissue development occurring during the last 60 days of gestation. (grobernutrition.com)
  • The heifer's growth rate is required such that she achieves her correct breeding weight at 15 months but is not allowed to get fat. (grobernutrition.com)
  • If the growth pattern is one of high energy alone, fat rather than milk-secreting tissue will be deposited in the udder. (grobernutrition.com)
  • Our objective was to determine the rate of acromegaly comorbidities once hypersecretion of growth hormone is controlled. (medscape.com)
  • In line with the results of OCR and ECAR, we found Mφ during cPE challenge showed higher glycolytic ATP (glycoATP) production rates and lower mitochondrial ATP (mitoATP) production rates which is mainly from OXPHOS. (stanford.edu)
  • A rare cancer found in the tissues of the gland that makes saliva. (rozlytrek.com)
  • In a comparison between docile, restless, nervous and aggressive buffaloes of Murrah breed, it was found that the docile individuals had a higher rate of concentrate intake, shorter let-down time, slightly longer milking time, higher daily milk yield, higher milk flow rate and a higher percentage of milk fat than the other groups of buffaloes. (indiadairy.com)
  • Hyper- and hypo-functioning of the thyroid influences mature kidney function indirectly by affecting the cardiovascular system and the renal blood flow, and directly by affecting glomerular filtration, electrolyte pumps, the secretory and absorptive capacity of the tubuli, and the structure of the kidney. (avmi.net)
  • 5 Functional in vitro assays indicate different physiological roles of MSCs related to their heterogeneity and tissue location of origin. (bmj.com)
  • Non-muscle cell contractility is critical for tissues to adopt shape changes. (elifesciences.org)
  • Although, the non-muscle myosin II holoenzyme (myosin) is a molecular motor that powers contraction of actin cytoskeleton networks, recent studies have questioned the importance of myosin motor activity cell and tissue shape changes. (elifesciences.org)
  • Overall, our data highlights that myosin activity is required for rapid cell contraction and tissue folding in developing Drosophila embryos. (elifesciences.org)
  • Cell shape changes and cell movements drive these tissue-scale transformations. (elifesciences.org)
  • In this and similar ways all of the fundamental forms of cell and tissue damage that cause aging are linked together, feeding from one another, making up a web of interacting forms of damage and consequences. (fightaging.org)
  • To understand the oxygen consumption rate (OCR), we used Seahorse XF Cell Mito Stress Test Kit with Seahorse XF96 analyzer. (stanford.edu)
  • However, most GEP studies have typically been performed on whole tissue samples, containing varying degrees of tumor cell content, which results in uncertainties in data analysis. (lu.se)
  • However, whether the level of TBA in maternal serum caused perinatal abnormality of pulmonary surfactant and fetal lung tissue morphological structure remains largely unknown. (hindawi.com)
  • But why do the units associated with air as the pathway represent an external concentration, and then those associated with soil and surface water as the pathways represent an internal, mass-based, dose rate? (cdc.gov)
  • mT was the preferred cytokinin both in terms of multiplication rate and rooting. (cas.cz)
  • This paper provides an updated review of the recent progress achieved in ultra-high dose rate radiobiology experiments employing laser-driven protons, including a brief discussion of the relevant methodology and dosimetry approaches. (frontiersin.org)
  • Then, for past soil and surface water contamination, an internal chemical dose rate, designated and MRL, is given in units of mg/kg/day. (cdc.gov)
  • This time the units are for an external concentration, in mg/L, instead of the internal dose rate of mg/kg/day shown in Fig. 17. (cdc.gov)
  • Hyperthyroidism accelerates several physiologic processes, a fact which is reflected in the decreased systemic vascular resistance, increased cardiac output (CO), increased renal blood flow (RBF), hypertrophic and hyperplastic tubuli, and increased glomerular filtration rate (GFR). (avmi.net)
  • It makes hormones that help control heart rate, blood pressure, body temperature, and weight. (rozlytrek.com)
  • During the development of an organism, tissues are sculpted into different three-dimensional forms. (elifesciences.org)
  • Proper rate of body weight gain from 3 to 10 months of age may be critical for optimum development of the mammary system. (grobernutrition.com)