Arthritis, RheumatoidArthritisDisease SusceptibilityGenotypeGenetic Predisposition to DiseaseArthritis, ExperimentalArthritis, InfectiousSynovial MembraneArthritis, JuvenileAntirheumatic AgentsPolymorphism, Single NucleotidePolymorphism, GeneticSynovial FluidAllelesRheumatoid FactorArthritis, PsoriaticJointsHaplotypesGene FrequencyGeneticsCase-Control StudiesArthritis, ReactiveGenetic VariationHLA-DRB1 ChainsGenome-Wide Association StudySynovitisOsteoarthritisHLA-DR AntigensMethotrexateAutoantibodiesLinkage DisequilibriumPhenotypeGenetic MarkersGenetics, PopulationSeverity of Illness IndexGenetic LinkageChromosome MappingBlood SedimentationAutoimmune DiseasesTumor Necrosis Factor-alphaMice, Inbred DBALupus Erythematosus, SystemicSulfasalazineRheumatoid NoduleImmunoglobulin GMetacarpophalangeal JointMolecular Sequence DataGold Sodium ThiomalatePeptides, CyclicHLA-DQ AntigensMicrobial Sensitivity TestsPolymerase Chain ReactionArthrographyModels, GeneticSpondylitis, AnkylosingMutationRheumatologyGenome, HumanRheumatic DiseasesEpistasis, GeneticRisk FactorsWrist JointGenetic Association StudiesGenetic LociHLA-DR4 AntigenSequence Analysis, DNAHLA-DQ beta-ChainsCohort StudiesTreatment OutcomeAntibodies, MonoclonalCrohn DiseaseDisease Models, AnimalQuantitative Trait LociHLA-DR3 AntigenMicrosatellite RepeatsFinger JointHLA AntigensImmunity, InnateGenetic TestingNod2 Signaling Adaptor ProteinCollagen Type IIBiological MarkersAsian Continental Ancestry GroupPlant DiseasesCytokinesGenetic Diseases, InbornEuropean Continental Ancestry GroupCitrullineComplement C4aMice, Inbred C57BLBase SequenceCells, CulturedAnti-Bacterial AgentsReceptors, Tumor Necrosis FactorTime FactorsGenes, MHC Class IIDrug Therapy, CombinationPolymorphism, Restriction Fragment LengthChromosomes, Human, Pair 6Homozygote