Tissue airway respiratory mucosa. Medical search. Frequent questions

Conchae are composed of pseudostratified columnar, ciliated respiratory epithelium with a thick, vascular, and erectile glandular tissue layer. (wikipedia.org)
The respiratory epithelium that covers the erectile tissue (or lamina propria) of the conchae plays a major role in the body's first line of immunological defense. (wikipedia.org)
The respiratory epithelium is partially composed of mucus-producing goblet cells. (wikipedia.org)
The respiratory epithelium also serves as a means of access for the lymphatic system, which protects the body from being infected by viruses or bacteria. (wikipedia.org)
When inhaled, nitrogen mustard damages the respiratory tract epithelium and may cause death. (cdc.gov)
Histologically, inflammatory polyps are composed of a core of vascularized fibrous connective tissue covered by squamous of columnar epithelium. (vin.com)
The epithelium lining the respiratory tract from the nasal fossa through the bronchi is called the respiratory mucosa and is characterized by a pseudostratified ciliated epithelium with abundant non-ciliated cells known as goblet cells. (medcell.org)
Specifically, to investigate the impacts on the pulmonary system, we propose to use a 3D model of human upper airway epithelium (MucilAir TM , Epithelix Sàrl, Geneva, Switzerland) reconstituted from tissues of 8 healthy and 8 asthmatic individual donors. (cas.cz)
The model represents a fully differentiated and functional respiratory epithelium consisting of basal, goblet and ciliated cells [26] . (cas.cz)
Lower airway epithelium served as the principal target for primary infection. (blogspot.com)
Epithelial intracytoplasmic inclusion bodies, consistent with Guarnieri bodies, were usually inconspicuous by light microscopy, but when present, were most readily apparent in the stratified squamous epithelium of the oral mucosa and epidermis. (blogspot.com)
Multinucleated syncytial cells were also occasionally observed in the stratified squamous epithelium of the tongue, tonsil, and skin, and in the intestinal mucosa. (blogspot.com)
While PCD may be suspected based on history, clinical signs, diagnostic imaging and endoscopy, final diagnosis requires the observation of ciliary structure abnormalities after ciliogenesis (i.e. culture of ciliated cells) of biopsies of ciliated epithelium (i.e. the nasal, tracheal or bronchial mucosa) with the use of transmission electron microscopy. (oldenglishsheepdogclubofamerica.org)
Eosinophil-mediated damage to the respiratory epithelium is a major pathogenetic mechanism in asthma. (edu.pk)
The human pathogen Bordetella pertussis targets the respiratory epithelium and causes whooping cough. (uni-wuerzburg.de)
Chronic bronchitis a type of obstructive lung disease that is caused by chronic inflammation of the airway, which causes recurrent damage to the respiratory epithelium in the bronchi, resulting in hypertrophy of the mucus-secreting glands. (lesperssi.org)
The distal airway epithelium from control and IPF/UIP subjects and HC was populated by basal and ciliated cells. (nih.gov)
The distal airway contains a pseudostratified mucocilary epithelium that is defined by basal epithelial cells and mucus cells that express MUC5B predominantly. (nih.gov)
Covered in respiratory epithelium and mucous cells, this is the most substantial part of the nasal cavity. (nih.gov)
A healthy process that occurs in the sinus cavities, termed mucociliary clearance, allows the ciliated epithelium (hair-like structures located on tissues), in coordination with mucus production, to continually remove waste from the sinuses by facilitating drainage and particle removal. (iprogressivemed.com)
With rare exceptions B. pertussis infections are restricted to the airways and do not usually disseminate beyond the respiratory epithelium. (frontiersin.org)
The bronchial mucosa is made of pseudostratified ciliated columnar epithelium with goblet cells and basal cells. (medscape.com)

The usefulness and limitations of various techniques used for assessing distal airways were also evaluated, including pulmonary function tests and imaging. (ersjournals.com)
CLINICAL FEATURES - Patients with granulomatosis with polyangiitis (GPA) typically have both upper airway and pulmonary involvement, although a minority may have just one or the other [ 1 ]. (medilib.ir)
In fact, it is known that the development of cell immunity in pulmonary tissues is largely independent of the events occurring in both peripheral circulation and distal lymphoid organs. (nature.com)
Eosinophils are a prominent feature in the pulmonary inflammation that is associated with allergic airway diseases, suggesting that inhibition of interleukin-5 is a viable treatment. (biomedcentral.com)
Therefore, exclusively inhibiting the actions of interleukin-5 can suppress at least one of the alleged causes of asthma, namely tissue damage due to eosinophil accumulation during pulmonary inflammation. (biomedcentral.com)
It is covered under the umbrella term of Chronic Obstructive Pulmonary Disease (COPD).The COPD spectrum ranges from Emphysema to Chronic Bronchitis and it occurs when the airways become inflamed and the air sacs in your lungs are damaged. (lesperssi.org)
Eosinophilic bronchitis (EB) is now known to be a feature not only of bronchial asthma, but also of cough variant asthma, atopic cough, isolated chronic cough, respiratory symptoms without asthma, allergic rhinitis, and chronic obstructive pulmonary disease (COPD). (lesperssi.org)

However, his condition deteriorated rapidly, and he died of respiratory obstruction 48 hours after admission. (cdc.gov)
It was concluded that both proximal and distal airways were involved in asthma and that distal airways were the major determinant of airflow obstruction. (ersjournals.com)
Although these airways contribute little to airflow obstruction in normal airways, studies have revealed that distal airways accounted for up to 50-90% of total airflow resistance in asthmatics [ 1 ], implying that distal airways were the main site of airflow obstruction in asthmatics. (ersjournals.com)
Nasopharyngeal polyps often result in signs of upper respiratory tract infection, upper airway obstruction, and possibly dysphagia. (vin.com)
It was concluded that she had chronic rheumatoid arthritis of the cricoarytenoid joints and that intubation of the trachea through the narrowed vocal cords had caused laryngeal oedema precipitating an acute upper airway obstruction. (ispub.com)
Despite the high incidence of rheumatoid involvement of the larynx, its presentation as acute upper airway obstruction is fortunately an uncommon event and has seldom been reported in recent anaesthetic literature. (ispub.com)
This stage of the disease is a potential hazard for the anaesthetist because intubation can cause laryngeal oedema in an already compromised airway precipitating respiratory obstruction. (ispub.com)
These poisonous gases then cause lung injuries, subsequently resulting in respiratory obstruction, cellular injury and organ failure. (thehealthsite.com)
The obstruction of airways in acute fatal asthma is due to contraction of bronchial smooth muscle, thickening of airway wall and intraluminal mucus and debris. (edu.pk)
After an incubation period of about 3-7 days, they cause the symptoms of a mild common cold/bronchitis (nasal obstruction, sneezing, runny nose, cough, headache, fever, pneumonia, asthenia, and inflammation in the airway) in avian and mammalian species. (scitcentral.com)
Attempts to do this with the use of foreign materials led to chronic infection, airway obstruction, migration of the prosthesis, erosion into major blood vessels and proliferation of granulation tissue. (biomedcentral.com)
Obstruction of the ostia leads to ciliary injury, mucosal edema, and general inflammation, which is further exacerbated by chronic colonization, in most cases with pathogens of the upper and lower respiratory tract such as Pseudomonas species, Staphylococcus aureus , and nontypable Haemophilus influenzae [ 7 ]. (hindawi.com)

Skin and mucosal surfaces of the respiratory and gastrointestinal tracts also exhibited variable proliferation of epithelial cells and subjacent fibroblasts. (blogspot.com)
Detectable poxviral antigen was limited to sites exhibiting obvious morphologic involvement and was most prominent within epithelial cells, macrophages, dendritic cells, and fibroblasts of affected tissues. (blogspot.com)
A. Microscopic view of the respiratory mucosa consisting of ciliated epithelial cells (i.e. presence of cilia at their apical surface). (oldenglishsheepdogclubofamerica.org)
Previous studies on the impact of CyaA on human epithelial cells have been carried out using cell lines derived from the airways or the intestinal tract. (uni-wuerzburg.de)
Here, we investigated the interaction of CyaA and its enzymatically inactive but fully pore-forming toxoid CyaA-AC- with primary human airway epithelial cells (hAEC) derived from different anatomical sites (nose and tracheo-bronchial region) in two-dimensional culture conditions. (uni-wuerzburg.de)
A deficiency of the CFTR leads to chloride channel dysfunction at the epithelial cells lining the airway and exocrine glands, causing accumulation of thickened mucous secretions. (hindawi.com)

Microscopic polyangiitis (MPA) affecting the respiratory tract is most often associated with alveolar hemorrhage [ 6,7 ]. (medilib.ir)
Airway and lung involvement - The most common respiratory symptoms in GPA and MPA are cough, hemoptysis (due to alveolar hemorrhage and/or tracheobronchial disease), dyspnea, and pleuritic pain. (medilib.ir)
The severity of symptoms and signs varies considerably from asymptomatic (one-third of patients) to acute and fulminant alveolar hemorrhage with respiratory failure. (medilib.ir)
These are located entirely within the lung and are represented by respiratory bronchioles, alveolar ducts, alveolar sacs, and alveoli. (medcell.org)
Each respiratory bronchiole branches into between 2 and 11 alveolar ducts that still contain smooth muscle fibers in their walls. (medcell.org)
Immunofluorescence was used to subtype mucus cells according to MUC5B and MUC5AC expression and to identify ciliated, basal, and alveolar type II (ATII) cells in tissue sections from control and IPF/UIP subjects. (nih.gov)

The present review is the summary of an expert workshop that took place in Vence (France) in 2007 on the role of distal airways in asthma. (ersjournals.com)
The evidence showing inflammation and remodelling in distal airways, and their possible involvement in asthma control and natural history, was reviewed. (ersjournals.com)
Finally, the available data studying the benefit of treatment better targeting distal airways in asthma was examined. (ersjournals.com)
Inflammation in distal airways appeared more intense in severe and uncontrolled asthma. (ersjournals.com)
Distal airways were poorly attained by conventional aerosol of asthma medications owing to their granulometry, being composed of 3-5 μm particles. (ersjournals.com)
Thus, it is not surprising that the roles of distal airways in the natural history of asthma have long been neglected. (ersjournals.com)
Organoculture systems to investigate inflammatory responses (cytokine release) in skin (normal, psoriasis, atopic dermatitis) gastrointestinal tissues (normal and IBD) and lung (normal, COPD, and asthma). (reprocell.com)
We will investigate the toxicity of real-world complete ambient air in human lung bronchi and olfactory mucosa (a proxy to brain effects) tissues from healthy and diseased donors (asthma, Alzheimer´s disease). (cas.cz)
Without immediate therapy, corresponding to with your bronchial asthma inhaler or bronchodilator, your respiratory will turn into extra labored. (com.ng)
In an asthma exacerbation, the respiratory price will increase, the heart rate increases, and the work of respiration will increase. (com.ng)
461,000 Asthma is a long-term inflammatory disease of the airways of the lungs. (com.ng)
Air pollution is involved in acute disorders like asthma exacerbations and upper and lower respiratory infections, including bronchiolitis, tuberculosis, and pneumoniae. (encyclopedia.pub)
Pollutants can also contribute to the onset of chronic asthma, and they can lead to a deficit in lung function and growth, long-term respiratory damage, and eventually chronic respiratory illness. (encyclopedia.pub)
Eosinophils are known to be an indirect marker of airway inflammation in asthma. (edu.pk)
Asthma is an inflammatory disease of the airways characterized by its reversible, reactive nature. (edu.pk)
Airway inflammation is present during an acute exacerbation of asthma, and is characterized by infiltration and activation of both eosinophils and neutrophils 2 . (edu.pk)
Asthma is the most common chronic respiratory disease, especially among children. (who.int)
Smoke (tobacco smoke, smoke from wood-burning or kerosene stoves and fireplace), aerosol sprays, strong odours (perfumes, cologne, gasoline fumes) and dust and air pollution can trigger asthma attacks by irritating sensitive airways. (who.int)

In daycare centers, respiratory organisms spread easily through large droplet transmission among young children with poor hygienic habits who share toys contaminated with respiratory secretions or saliva. (cdc.gov)
Endoscopy revealed inflamed mucosa, moderate to large amounts of mucopurulent secretions along all the upper and lower airway tracts. (oldenglishsheepdogclubofamerica.org)
They also may be produced through manipulation of lesions or processing of tissue or secretions in the hospital or laboratory. (cdc.gov)
The infected individuals shed virus in nasal secretions and mucosa resulting in its transmission that can often be controlled, at least partially, by following hygienic measures. (scitcentral.com)

Diphtheria is an acute respiratory disease caused by infection with Corynebacterium diphtheriae . (cdc.gov)
Shock is a state of compromised tissue perfusion that causes cellular hypoxia and is defined as a syndrome initiated by acute hypoperfusion, leading to tissue hypoxia and vital organ dysfunction (see the image below). (medscape.com)
We recently provided evidence that the generation of endogenous extracellular vesicles (EVs) engineered for the incorporation of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 Nucleocapsid (N) protein induced immunity in the lungs of K18-hACE2 transgenic mice, which then can survive the lethal virus infection. (nature.com)
Several vaccines were developed and distributed within an unprecedentedly short time in response to the spread of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2. (nature.com)
Air pollution abatement policies, are contributing to mitigating air quality issues, but more efforts should be encouraged to improve acute childhood respiratory disease with possible positive long-term effects on lung function. (encyclopedia.pub)
A by-product of burning polyvinyl (a common compound used in upholstery and furniture), hydrogen chloride causes acute bronchitis by destroying the airways mucosa. (thehealthsite.com)
Studies in animals infected experimentally with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19, provide opportunities to study aspects of the disease that are not easily investigated in human patients. (nature.com)
Currently novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/2019- nCoV) pandemic has resulted in millions of deaths around the globe. (scitcentral.com)
Lung transplantation-related pathology encompasses a spectrum of disorders that include, but are not limited to, indications for lung transplantation (seen in explanted lungs), surgical complications (airway anastomotic and vascular complications), ischemia-reperfusion injury, rejection (acute and chronic), infections, and posttransplantation lymphoproliferative disorders (PTLDs). (medscape.com)

Innate lymphoid cells (ILCs), a heterogeneous cell population, are critical in orchestrating immunity and inflammation in the intestine, but whether ILCs influence immune responses or tissue homeostasis at other mucosal sites remains poorly characterized. (nih.gov)
INTRODUCTION - "Classic" granulomatosis with polyangiitis (GPA) is a form of systemic vasculitis (polyangiitis) with necrotizing granulomatous inflammation of the upper and lower respiratory tracts, systemic necrotizing vasculitis, and necrotizing glomerulonephritis [ 1,2 ]. (medilib.ir)
Once activated, these proteases are capable of degrading various extracellular matrix components, which can lead to tissue damage and chronic inflammation. (justia.com)
this in turn results in chronic mucus plugging and inflammation of nasal cavities, trachea and lower airways. (oldenglishsheepdogclubofamerica.org)
As a consequence, clinical signs will include chronic respiratory abnormalities such as rhinosinusitis, bronchitis, bronchopneumonia and bronchiectasis (i.e dilation of bronchi secondary to chronic inflammation). (oldenglishsheepdogclubofamerica.org)
We can also assess species differences in airway inflammation, using our ex vivo precision-cut lung slice (PCLS) and parenchymal explant models. (reprocell.com)
Lung microbiota dysbiosis is related to inflammation, pathological airway alterations, immune responses, and the aggravation of clinical symptoms in patients with COPD [6] . (researchsquare.com)
Pathogens stimulate inflammatory cells to produce inflammatory media that often destroy the immune function of the airway and mucosa, leading to chronic inflammation and lung microbiota dysbiosis, further aggravating COPD [7] . (researchsquare.com)

This is exemplified by the main bronchi, large bronchi, small bronchi, bronchioles, and alveoli inhalation toxicity of diacetyl, a component of butter flavoring with tissue dimensions obtained from the literature. (cdc.gov)
The respiratory airways extend from the respiratory bronchioles to the alveoli. (medcell.org)
The respiratory bronchioles have a diameter of 0.5 millimeters and feature a few alveoli scattered along their walls. (medcell.org)
These specialized cells generally function to clear particles depositing in the alveoli by enveloping them in a process called phagocytosis and then moving to the airways, where the particle-containing macrophages are transported out of the lungs via mucociliary clearance. (cdc.gov)
It is composed of an extensive branching system of airway passages that transmit the air from the atmosphere to the alveoli (the gas-exchange units). (medscape.com)
The last 2-3 generations of bronchioles are lined with alveoli and make up the respiratory zone. (medscape.com)
Alveoli, the functional units of the respiratory system, start appearing at the level of the respiratory bronchioles. (medscape.com)

Early pathological changes of rheumatoid arthritis in the larynx affect the synovium and can present with symptoms of pain, tenderness, dysphonia, redness and swelling of the mucosa. (ispub.com)
When there are signs of granular nasal mucosa, a biopsy is both a specific and sensitive way of diagnosing WG but where there are no symptoms or signs then a biopsy is unlikely to help. (bmj.com)
For example, anosmia is a common presentation, and many patients with anosmia show no or only minor respiratory symptoms 1 . (nature.com)
In contrast to animals, wherein they have been shown to infect several tissues causing a large variety of diseases, mainly human respiratory infections with mild common cold-like symptoms, with occasional gastrointestinal problems have been reported. (scitcentral.com)
Clinical features of lung transplantation-related pathology can range from an absence of symptoms to signs and symptoms of respiratory distress and/or infection and are not detailed in this article. (medscape.com)

The standardized botanicals and nutrients in Sinatrol target sinus related issues by clearing airway passages, decreasing the viscosity of mucus and supporting immune health. (iprogressivemed.com)

At this phase, dendritic cells (DCs) of the nasal mucosa take up the allergen, process it, and nest it to the draining lymph node, presenting it to the naive CD4 + T cells [ 4 , 5 ]. (hindawi.com)

For both the human and rat models, a close more effectively to the lower airways of the human than the rat. (cdc.gov)
Also, as the air passes through, the nasal cavity removes minute airborne particles and other debris before the air reaches the lower airways. (nih.gov)

As a ciliated mucous membrane with shallow blood supply, the nasal mucosa cleans and warms the inhaled air in preparation for the lungs. (wikipedia.org)
In the lamina propria there are mixed seromucous (protein- and mucous-secreting) glands, lymphatic tissue, and broad veins. (medcell.org)
Mucous and seromucous glands and diffuse lymphatic tissue are associated with smaller bronchi but are not found distal to the region where there is a loss of cartilage plates. (medcell.org)

From the upper airways, pathogens may invade adjacent structures, such as the lungs, middle ear, or nasal sinuses, and may penetrate into the bloodstream, causing invasive diseases. (cdc.gov)
In the past, the term "limited" GPA was used to describe patients with clinical findings isolated to the upper respiratory tract or lungs, which occurs in approximately one-fourth of cases. (medilib.ir)
Many patients with disease limited to upper respiratory tract or lungs subsequently develop systemic involvement [ 9 ]. (medilib.ir)
Induction of effective immunity in the lungs should be a requisite for any vaccine designed to control the severe pathogenic effects generated by respiratory infectious agents. (nature.com)
Lymphocytes in lungs are maintained separately from the pool of circulating lymphocytes, and their continuous loss through intraepithelial migration toward the airways is constantly replenished by homeostatic proliferation 9 . (nature.com)
The largest size asbestos particles tend to deposit on the nasal mucosa or the oropharynx and are sneezed out or swallowed never reaching the lungs [NIOSH 2011a]. (cdc.gov)
A tracheal or bronchial rupture is a tear or break in the windpipe (trachea) or bronchial tubes, the major airways leading to the lungs. (medlineplus.gov)
Bronchitis Bronchitis is swelling of the lining of the large airways called bronchi in the lungs. (lesperssi.org)

Triggered by the flow of the air, the pressure of the air in the nose, and the quality of the air, impulses from the nasal mucosa are transmitted by the trigeminal nerve to the breathing centres in the brainstem, and the generated response is transmitted to the bronchi, the intercostal muscles, and the diaphragm. (wikipedia.org)
When the bronchi enter the lung, the C-shaped cartilages that characterize the trachea and primary bronchi are replaced by irregular plates or cartilage that completely surround the cylindrical muscular airway tube. (medcell.org)
At REPROCELL, our scientists can compare the effects of your test compounds on the constriction or relaxation of animal and human airways (bronchi). (reprocell.com)
By definition, bronchi are airways with cartilaginous walls. (medscape.com)
The amount of cartilage in the walls of bronchi progressively decreases and eventually disappears by the time the bronchi divide into airways of about 1 mm diameter. (medscape.com)
The initial 16 divisions or generations of bronchi make up the conducting zone of the airways, in which gas is transported from and to the exterior via trachea and nasal passages. (medscape.com)

The respiratory tract was modeled as a series of airways: nose, trachea, toxicity data difficult (USEPA, 1994) . (cdc.gov)
She had a CT scan which showed soft tissue swelling of the cricoarytenoid joints as well as constriction of the trachea posteriorly as a result of adduction of the vocal cords. (ispub.com)
The bronchus (from Greek bronkhos "windpipe") is the part of the respiratory system that connects the trachea to the lung parenchyma. (medscape.com)

The smaller airways that lack cartilage are called bronchioles. (medscape.com)

The mucosa in WG has a granular quality and stagnant mucus superinfected with nasal commensals from the nasal vestibule can coat the septum and lateral nasal wall (see fig 1 ). (bmj.com)
Crusting and mucus stagnation with erythematous granular mucosa in the left nasal airway. (bmj.com)
This type of epithelial lining also secretes mucus that coats the lining and helps with the mucociliary clearance of minute aerosolized particles that become trapped in the nasal mucosa. (nih.gov)
Sinatrol contains a synergistic blend of ingredients that support sinus health by increasing mucociliary clearance, decreasing the build-up of mucus and boosting immune response during seasonal respiratory challenges. (iprogressivemed.com)
Stinging nettles leaf balance hyper-immune response and N-acetyl cysteine clear the airways by promoting normal viscosity of mucus. (integrativehealthcarespringfieldmo.com)
Specialized cells of the mucosal tissue, known as goblet cells, secrete a thin layer of mucus to absorb microbes and allergens, such as dust, dirt, pollen, and mold, inhaled through the nose. (integrativehealthcarespringfieldmo.com)
Sinatrol contains a synergistic blend of nutrients and botanical ingredients to quickly boost immune response, decrease mucus build-up and increase mucociliary clearance during upper respiratory challenges. (integrativehealthcarespringfieldmo.com)
Standardized botanical extracts and nutrients support sinus health by reducing the viscosity of mucus, clearing airway passages, and promoting nasal microbial and inflammatory balance. (integrativehealthcarespringfieldmo.com)
N-Acetyl Cysteine (NAC) is an amino acid that boosts antioxidant function and is commonly used as an agent to help clear sinus and airway congestion caused by mucus overproduction. (integrativehealthcarespringfieldmo.com)
Although the dominant clinical features of CF are lower respiratory tract infections and pancreatic insufficiency, the vast majority of CF patients will also develop chronic rhinosinusitis due to sinonasal mucus accumulation [ 2 - 5 ]. (hindawi.com)

Type 1 damage to the large airways involves sloughing of airway mucosa as pseudomembranes. (msdmanuals.com)

In humans, the conchae divide the nasal airway into four groove-like air passages, and are responsible for forcing inhaled air to flow in a steady, regular pattern around the largest possible surface area of nasal mucosa. (wikipedia.org)
This powerful combination actively promotes healthy nasal and sinus passages for individuals with elevated histamine and respiratory irritation. (integrativehealthcarespringfieldmo.com)
The sinuses and nasal passages are lined with soft tissue, called mucosa, that feature thin, hair-like projections called cilia. (integrativehealthcarespringfieldmo.com)

Notably, mouse ILCs accumulated in the lung after infection with influenza virus, and depletion of ILCs resulted in loss of airway epithelial integrity, diminished lung function and impaired airway remodeling. (nih.gov)
Collectively, our results demonstrate a critical role for lung ILCs in restoring airway epithelial integrity and tissue homeostasis after infection with influenza virus. (nih.gov)
To understand the cause(s) of this morbidity and mortality better, we assessed the tissue distribution of infectious virus and viral genomic RNA at 2, 4 and 6 days post infection (dpi) in mice receiving 10 5 PFU of SARS-CoV-2. (nature.com)
HHV-5, also known as cytomegalovirus (CMV), causes a primary infection of the salivary glands and other tissues, and it is believed to have a chronic form. (medscape.com)

Most bacterial pathogens responsible for such infections are enclosed by polysaccharide capsules that protect them from phagocytosis and complement- mediated killing, ensuring their persistence on the respiratory mucosa and survival in the bloodstream and deep body tissues. (cdc.gov)
Some respiratory viral infections can aggravate allergic rhinitis, such as a respiratory syncytial virus (RSV) and human metapneumovirus (hMPV). (hindawi.com)
Human respiratory syncytial virus (RSV) is a ubiquitous virus of worldwide distribution and is the leading cause of infant morbidity from respiratory infections. (intechopen.com)
Primary ciliary dyskinesia (PCD), previously called immotile cilia syndrome (ICS), is a divers group of inherited structural and functional abnormalities affecting the cilia of the respiratory tract mucosa and other organs which results mainly in recurrent respiratory tract infections. (oldenglishsheepdogclubofamerica.org)

Pertussis or whooping cough, mainly caused by Bordetella pertussis , is a severe respiratory disease that can affect all age groups but is most severe and can be life-threatening in young children. (frontiersin.org)
Whooping cough, also referred to as pertussis, is a severe respiratory disease that can be life threatening in newborns and non-vaccinated young children. (frontiersin.org)
The main causative agent of whooping cough is Bordetella pertussis ( 2 ), a gram negative coccobacillus which is able to colonize the human upper respiratory tract by attaching to the ciliated cells. (frontiersin.org)

The conchae comprise most of the mucosal tissue of the nose and are required for functional respiration. (wikipedia.org)
The authors suggest that smooth muscle hyperresponsiveness to substance-P caused by the perfusion of airways with HOCl occurs through HOCl inactivation of mucosal NEP. (cdc.gov)
Mucosal ion channel assays, investigating sodium, chloride, and potassium channels in intact mucosa of the respiratory and gastrointestinal systems. (reprocell.com)
Bromelain enhances the absorption of quercetin and supports mucosal tissue health. (integrativehealthcarespringfieldmo.com)

Therefore, protection at the level of the respiratory mucosa may be helpful for an improved control of pertussis. (frontiersin.org)

Respiratory bronchiole e. (histology-world.com)

The major features of respiratory tract involvement in GPA and MPA will be reviewed here. (medilib.ir)
The relative degree of involvement among lymphoid tissues suggested that tonsil, mediastinal, and mandibular lymph nodes were also infected early in the course of the disease, and may have served as additional, although subordinate, sites of primary replication. (blogspot.com)
Larynx: Throat tightness, voice changes, and breathing trouble (indicators of possible airway involvement), potentially life-threatening. (medscape.com)
Despite the strong association of this airway epithelial marker with disease, little is known of mucin expressing structures or of airway involvement in IPF/UIP. (nih.gov)

The bronchial wall is made up of mucosa, lamina propria, smooth muscle, and submucosa with interspersed cartilage. (medscape.com)

We made a clinical diagnosis of respiratory diphtheria. (cdc.gov)
Achieve early indication of clinical drug performance using ethically sourced human fresh tissues. (reprocell.com)
With our unparalleled access to ethically donated human tissue, REPROCELL has developed the most clinically relevant functional human tissue models, that avoid species differences, improve understanding of disease pathology and reduce clinical attrition by demonstrating proof of concept in human disease. (reprocell.com)
Additionally, we will soon be launching a clinical iPSC manufacturing service in which we can identify donors, collect tissue, derive seed stock iPSCs, and generate Master and Working Cell Banks in accordance with clinical regulatory guidelines. (reprocell.com)
The clinical manifestations of GPA and MPA outside the respiratory tract are discussed separately. (medilib.ir)
Approximately one-third of all respiratory abnormalities during human clinical trials can be attributed to unforeseen drug-mediated changes in airway resistance. (reprocell.com)
More recently, few clinical attempts have offered encouraging results with ex vivo or stem cell-based engineered airways and tracheal allografts implanted after heterotopic revascularization. (biomedcentral.com)

Although advances in tissue typing and cross-match testing have helped to deter severe transplant rejection, rejection may result from direct cellular attack (cellular rejection) or be mediated by antibodies (humoral rejection). (medscape.com)

Computed tomography showed extensive soft tissue edema causing near-complete airway narrowing from the choana to supraglottis and multiple enlarged cervical lymph nodes. (cdc.gov)
Both types of abscesses are well demonstrated on lateral soft tissue neck x-ray or CT scan. (entcentergr.com)
A widening of the prevertebral retropharyngeal soft tissue may be noted. (entcentergr.com)
The sinuses are composed of hollow cavities that are lined with soft tissue, called mucosa. (iprogressivemed.com)

Both proximal and distal airways might be targeted either by delivering medications systemically or by aerosol of extra-fine particles. (ersjournals.com)
As one example, the respiratory tract represents one of the largest surface areas in the body and acts as an interface with the external environment that is frequently exposed to foreign particles or pathogens. (biomedcentral.com)
The most important means of removal of insoluble asbestos particles deposited in respiratory tract airways is by mucociliary clearance. (cdc.gov)
Particles that get past the nasal vestibule then become trapped in the mucosa of the nasal cavity. (nih.gov)

Studies of distal airways have proved difficult, owing to their small size and their peripheral location. (ersjournals.com)
Staining patterns were quantified for distal airways (Control and IPF/UIP) and in honeycomb cysts (HC). (nih.gov)
MUC5B-expressing cells (EC) were detected in the majority of control distal airways. (nih.gov)
The frequency of MUC5B+ and MUC5AC+ distal airways was increased in IPF/UIP subjects. (nih.gov)

We will expose MucilAirTM tissues derived from 8 asthmatic and 8 healthy subjects and hOM from 8 AD and 8 healthy controls to ambient air for up to 6 hours/day for 5 consecutive days. (cas.cz)
Lavage fluid from the lumen of the asthmatic airway contains numerous mediators including histamine, prostaglandins (predominantly PGD2 and PGF2), leukotrienes, kinins, kallikrein, and eosinophil derived major basic protein. (edu.pk)

Although the respiratory system signs are usually the most important, several signs related to pathology in other tissues with ciliated epithelia or microtubules can occur, such as otitis media, infertility in males and females, hydrocephalus, and renal fibrosis or dilation of renal tubules. (oldenglishsheepdogclubofamerica.org)

This trend has substantial public health consequences because the incidence of infectious diseases in general, and of those caused by respiratory pathogens in particular, has substantially increased among daycare center attendees. (cdc.gov)
It is likely that L-DCs play an important role in antigen uptake and processing of respiratory pathogens and are major contributors to respiratory tract immunity and may be ideal tools for future in vitro or ex vivo studies. (biomedcentral.com)
Bacteria in the respiratory tract resist colonization by foreign pathogens. (researchsquare.com)

Inhaled asbestos fibers are deposited in the upper and lower respiratory tracts. (cdc.gov)

The muscles, vessels and visceral structures of the neck are encased in connective tissue. (entcentergr.com)
Fascial spaces are potential areas between the connective tissues. (entcentergr.com)

The flow of blood to the nasal mucosa in particular the venous plexus of the conchae is regulated by the pterygopalatine ganglion and heats or cools the air in the nose. (wikipedia.org)
They invade the respiratory tract via the nose. (scitcentral.com)
Rhinosinusitis is an inflammatory process of multifactorial etiology, involving the mucosa of the nose and one or more sinus. (hindawi.com)

Thus in cases of advanced rheumatoid arthritis alternatives to endotracheal intubation like a laryngeal mask airway or a regional technique may be more appropriate 7 . (ispub.com)

Focuses on the role of bioactive foods in mediating the riskof arthritis and other inflammatory tissue diseases. (current-reports.com)
This invention relates to a compound of formula I and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases. (justia.com)
The eosinophil is therefore an ideal target for selectively inhibiting the tissue damage that accompanies allergic diseases, without inducing the immunosuppressive consequences that can arise from systemic use of pleiotropic drugs such as steroids. (biomedcentral.com)
Yifei Sanjie Formula (YS) is widely used to treat diseases in respiratory systems, yet its mechanisms are little known. (researchsquare.com)

Some of the smaller inhaled asbestos fibers are deposited on the surface of the larger airways where some of them are cleared by mucociliary transport and swallowing. (cdc.gov)
Upper respiratory challenges may impair this process, known as mucociliary clearance, and contribute to fluid entrapment within the sinus cavities. (integrativehealthcarespringfieldmo.com)

The conchae are located laterally in the nasal cavities, curling medially and downward into the nasal airway. (wikipedia.org)

With disease and chronicity, the tympanic bullae become sclerotic and thickened, and the tympanic cavity may contain a fluid or tissue density. (vin.com)
Since olfactory mucosa is considered one of the most feasible routes of air pollutants entry into the brain [27] , we will further study the effects of air pollution exposure in human olfactory mucosa cells (hOM) obtained from 8 healthy subjects and 8 Alzheimer's disease (AD) patients (provided by a collaborative institution - Prof. Katja Kanninen, University of Eastern Finland). (cas.cz)
The durability and retention of the fibers in lung tissue and elsewhere in the body may lead to a risk of disease. (cdc.gov)
The incubation period of RSV respiratory disease is estimated to be three to five days (Black, 2003). (intechopen.com)
Lanari, M. Outdoor Air Pollution and Childhood Respiratory Disease. (encyclopedia.pub)
Outdoor Air Pollution and Childhood Respiratory Disease" Encyclopedia , https://encyclopedia.pub/entry/45465 (accessed November 30, 2023). (encyclopedia.pub)
White V, Ruparelia P. Respiratory disease. (medlineplus.gov)
It is believed to chronically persist in salivary gland tissue in some hosts, and oral shedding is the probable route of disease transmission. (medscape.com)
However, there are a number of significant features peculiar to the donkey that practitioners should be aware of when attempting to investigate and treat respiratory disease. (ivis.org)

Implantation of nonviable tissues-chemically treated, frozen or lyophilized-has been associated with poor functional results. (biomedcentral.com)

nasal vestibule, respiratory region, and olfactory region. (nih.gov)

Exposure to high concentrations of this vapor in certain vapor was allowed to absorb (or desorb) from tissues based on mass occupations has been associated with bronchial wall thickening transfer coefficients. (cdc.gov)

For immune defense, the respiratory tract contains DCs that function as a robust antigen presentation system. (biomedcentral.com)
Sinatrol is a specialized preparation of botanicals and nutrients formulated to support immune health and provide immediate support for respiratory challenges. (iprogressivemed.com)

12 hours later an anaesthetist and an ENT surgeon were called to attend to her urgently because she was in respiratory distress. (ispub.com)

2003]. Still, many asbestos fibers are retained in lung tissue for many years. (cdc.gov)
Virus replicated to high titres in lung tissue at 2 dpi and decreased at 4 and 6 dpi (Fig. 1b ). (nature.com)
This allele was strongly associated with increased MUC5B gene expression in lung tissue from unaffected subjects. (nih.gov)

Interestingly, these chemosensory GPCRs (csGPCRs) are expressed in several tissues of the body where they are supposed to play a role in biological functions other than chemosensation. (mdpi.com)

Tracheas were isolated from male Hartley-guinea-pigs, and used for airway contraction studies. (cdc.gov)

Another by-product of fire is carbon dioxide, which can increase respiratory drive and make breathing difficult. (thehealthsite.com)

Anatomy34

Organisms4

Diseases23

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment26

Phenomena and Processes14

Disciplines and Occupations2

Technology, Industry, Agriculture1

Health Care1

Epithelium22

Pulmonary7

Obstruction12

Epithelial cells6

Alveolar6

Asthma18

Secretions4

Acute9

Inflammation8

Alveoli7

Symptoms5

Decreasing the viscosity of mucus1

Dendritic cells1

Lower airways2

Mucous3

Lungs8

Bronchi6

Trachea3

Bronchioles1

Mucus10

Large airways1

Passages3

Infection4

Infections4

Cough3

Mucosal4

Level of the respiratory1

Bronchiole1

Involvement4

Cartilage1

Clinical7

Severe1

Soft tissue4

Particles4

Distal airways4

Asthmatic2

Pathology1

Pathogens3

Tracts1

Connective2

Nose3

Laryngeal1

Diseases4

Mucociliary2

Nasal cavities1

Disease9

Functional1

Olfactory1

Bronchial wall1

Immune2

Distress1

Lung tissue3

Several tissues1

Contraction1

Carbon dioxide1