• Tumor glucose use in patients with non-islet-cell tumors has been difficult to measure, particularly in hepatoma, because of hepatic involvement by neoplasm. (jci.org)
  • Desmoid tumor constitute about 0.03% of sof tissue tumors and about 3% of all neoplasm with strong tendency to recur and local invasion. (iomcworld.com)
  • Tumors of the soft tissues composed of large eosinophilic cells. (beds.ac.uk)
  • Seven patients with ALK-positive mesenchymal tumors, including inflammatory epithelioid cell sarcoma, undifferentiated sarcoma, histiocytic neoplasm, smooth muscle tumor of uncertain malignant potential (STUMP), and atypical fibrohistiocytic tumor, were included on the basis of aberrant ALK immunoexpression. (yonsei.ac.kr)
  • In addition, larger tumors typically demonstrate areas of coagulative tumor necrosis and hyalinized tissue. (mayocliniclabs.com)
  • Malignant peripheral nerve sheath tumors are neoplasms involving the peripheral nerve. (mayocliniclabs.com)
  • All categories of soft tissue tumors have been reported to involve the upper aerodigestive tract. (basicmedicalkey.com)
  • These tumors have markedly different prognoses and require different treatments than those for soft tissue tumors. (basicmedicalkey.com)
  • Fibroblastic or myofibroblastic tumors make up the majority of soft tissue tumors of the aerodigestive tract and range from nonneoplastic or benign proliferations (fibromas) to high-grade malignancies (undifferentiated high-grade pleomorphic sarcomas). (basicmedicalkey.com)
  • Glioneuronal and neuronal tumors (GNTs) are rare neoplasms composed of neural and glial elements frequently located in the temporal lobe. (bvsalud.org)
  • Smooth muscle tumors represent the second most common mural mesenchymal neoplasm in the gastrointestinal tract, but established criteria for prognostic assessment of these tumors are lacking. (elsevierpure.com)
  • A large cohort of surgically resected intramural gastrointestinal smooth muscle tumors from 31 institutions was analyzed to identify potential prognostic features. (elsevierpure.com)
  • In the future the discovery may secure more precise treatment of tumors without causing damage to healthy tissues. (news-medical.net)
  • Accordingly, pleomorphic "adult"-type rhabdomyosarcoma and rhabdomyoma are the soft tissue tumors in which myoglobin is identified most often. (celltechgen.com)
  • Benign smooth muscle tumors, or leiomyomas, are common, well-circumscribed neoplasms that can arise from smooth muscle cells anywhere in the body, but are encountered most commonly in the uterus [1]. (peertechzpublications.org)
  • Tumors arising from the placental tissue include two distinct histological types: the benign vascular tumor, chorangioma, and very rarely, choriocarcinoma. (biomedcentral.com)
  • [ 1 ] Intestinal leiomyosarcomas are mesenchymal tumors of smooth muscle origin. (medscape.com)
  • GISTs, however, have been shown to lack characteristics of smooth muscle tumors on histologic examination. (medscape.com)
  • Approximately 1-2% of solid tumors are soft-tissue sarcomas, and leiomyosarcomas comprise roughly 2-9% of these sarcomas. (medscape.com)
  • [ 2 ] Studies in immunohistochemistry confirm that the tumors are almost totally matured neoplasms of clonal origin. (medscape.com)
  • A general term for a malignant neoplasm derived from muscular tissue. (wakehealth.edu)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • A variety of rare sarcoma having a reticulated fibrous stroma enclosing groups of sarcoma cells, which resemble epithelial cells and are enclosed in alveoli walled with connective tissue. (ouhsc.edu)
  • It is a slow-growing, persistent, and locally aggressive neoplasm of epithelial origin. (washington.edu)
  • It should be noted that the vast majority of neoplasms of the upper aerodigestive tract are epithelial and that some of these can show a spindle cell phenotype, e.g., spindle cell or sarcomatoid carcinoma and myoepitheliomas. (basicmedicalkey.com)
  • Because of this, one should be comfortable using immunohistochemistry or other methods with the diagnosis of these lesions, and to help exclude epithelial or melanocytic neoplasms ( Table 11.1 ). (basicmedicalkey.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • This is followed by coverage of neoplasms in the more traditional categories of epithelial, mesenchymal, and other categories. (abdominalkey.com)
  • Systemic Sclerosis Systemic sclerosis is a rare, chronic autoimmune connective tissue disorder characterized by degenerative changes and scarring in the skin, joints, and internal organs and by blood vessel abnormalities. (msdmanuals.com)
  • This suggests that circulating IGF-II-like proteins are partial insulin agonists, and that hypoglycemia in hepatoma with IGF-II production is predominantly due to glucose uptake by skeletal muscle and suppression of glucose production. (jci.org)
  • One of these rare cancers is Rhabdomyosarcoma (RMS), an aggressive neoplasm that originates in skeletal muscle from childhood to adulthood and leads to 3 different subtypes. (ibecbarcelona.eu)
  • In this PhD, the student will aim to recapitulate RMS biology using OoC to study the interactions and biochemical crosstalks between RMS tumor, its microenvironment (TME), and healthy skeletal muscle. (ibecbarcelona.eu)
  • and 2) the fields of skeletal muscle diseases and clinical and translational RMS research. (ibecbarcelona.eu)
  • The candidate will develop tissue engineering protocols to create 3D skeletal muscle tissues and fabricate new biomaterials to encapsulate cells. (ibecbarcelona.eu)
  • Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue. (omeka.net)
  • Results: Cancer-associated cachexia symptoms of the transgenic mice model used in this study mimic the progression of CAC seen in humans, including drastic body weight loss, skeletal muscle atrophy, and adipose tissue wasting. (nebraska.edu)
  • The field of activity of reconstructive surgery is very diverse: from the removal of skin neoplasms to laborious operations for the reconstruction of skin, muscle and bone tissues. (treatmentrussia.com)
  • Odontogenic keratocyst is an aggressive cyst known for its rapid growth and its tendency to invade the adjacent tissues, including bone. (washington.edu)
  • larger OKCs tend to expand bone, but mildly- obvious clinical expansion (which is the case in this patient) should be viewed with suspicion for a neoplasm . (washington.edu)
  • WHO Classification of Tumours Soft Tissue and Bone Tumours, 5th ed. (mayocliniclabs.com)
  • An eccentric contraction of muscle on the tensile side serves to decrease the tensile force applied to the bone. (musculoskeletalkey.com)
  • As muscle becomes fatigue, this protective mechanism is weakened and as a result the bone is subjected to higher repetitive forces leading to bone fatigue. (musculoskeletalkey.com)
  • Leiomyosarcomas are rare mesenchymal neoplasms characterized by a smooth muscle differentiation pattern. (oncotarget.com)
  • Because myoglobin appears relatively late in the maturational sequence of striated muscle, it is typically undetectable immunohistologically in embryonic neoplasms that show differentiation toward that tissue. (celltechgen.com)
  • Cutaneous leiomyomas are benign soft-tissue neoplasms that arise from smooth muscle (arrector pili). (medscape.com)
  • Cutaneous leiomyomas can develop wherever smooth muscles are present, but malignant transformation probably does not occur. (medscape.com)
  • However, genital leiomyomas are usually asymptomatic solitary lesions arising from the dartoic, vulvar, or mammillary muscles in the genital region or on the nipple. (medscape.com)
  • Cutaneous leiomyomas are known to arise from three locations viz, arrector pili muscle, dartos muscle in the scrotal sac, and smooth muscle layer of blood vessels. (panafrican-med-journal.com)
  • Smooth muscle neoplasms called leiomyomas are benign soft tissue neoplasms. (panafrican-med-journal.com)
  • Fetal rhabdomyoma occurs most often in the subcutaneous tissues of the head and neck in children between birth and age 3 years. (medscape.com)
  • The fetal rhabdomyoma is usually found in the subcutaneous tissues of the head and neck. (medscape.com)
  • Angiomyolipoma (AML) of classic type are benign mesenchymal neoplasms composed of blood vessels, smooth muscle, and adipose tissue. (pediagenosis.com)
  • Background: Cancer-associated cachexia (CAC) is a complex syndrome of progressive muscle wasting and adipose loss with metabolic dysfunction, severely increasing the morbidity and mortality risk in cancer patients. (nebraska.edu)
  • Morphometry and signalling markers of muscle atrophy (n ≥ 6) and adipose tissue wasting (n ≥ 7) were assessed during CAC progression. (nebraska.edu)
  • The adipose tissue wasting was based on thermogenesis, supported by the up-regulation of uncoupling protein 1 (UCP1). (nebraska.edu)
  • The mouse model in this study showed proteolysis in muscle atrophy, browning in adipose tissue wasting, elevation of serum activin A and GDF15, and atrophy of pancreas and liver. (nebraska.edu)
  • Leiomyosarcoma of somatic soft tissues: a tumor of vascular origin with multivariate analysis of outcome in 42 cases. (mayocliniclabs.com)
  • George S, Serrano C, Hensley ML, Ray-Coquard I. Soft Tissue and Uterine Leiomyosarcoma. (mayocliniclabs.com)
  • Of this uncommon group of highly malignant neoplasms, the leiomyosarcoma is the most common histiotype. (medscape.com)
  • Purpose: We investigated the effect of a neurovascular intact gracilis muscle urethral wrap to restore urinary continence in men with severe stress urinary incontinence after radical retropubic prostatectomy. (elsevierpure.com)
  • Conclusions: An autologous gracilis muscle urinary neosphincter can be constructed in the bulbous urethra in a fashion similar to that of the artificial urinary sphincter with encouraging results in this preliminary series. (elsevierpure.com)
  • Leiomyosarcomas are malignant neoplasms of smooth-muscle cells that typically occur from middle age to older individuals. (mayocliniclabs.com)
  • Leiomyosarcomas (LMS) are sarcomas that comprise spindle-cell neoplasms that develop from smooth muscle tissue and affect approximately 1 out of 100,000 Americans per year [ 2 - 4 ]. (oncotarget.com)
  • Wilms tumor is believed to arise from embryonic tissues called nephrogenic rests that fail to undergo normal involution ( 7 ). (abdominalkey.com)
  • Contrary, Organ-on-a-chip (OoC) devices offer new cancer-modeling and drug discovery approaches by combining biologically relevant in vitro models of tissues and organs with integrated analytical biosensors. (ibecbarcelona.eu)
  • The authors used various nomenclatures to describe conditions related to the presence of IgG4 until 2010 in Kanazawa, where it was unified as an "IgG4-related disease" with the consensus that it can affect various organs, including the thyroid and the eye with its adnexa and extraocular muscles [ 4 ]. (hindawi.com)
  • The lesion was broad-based and firmly attached to the underlying tissues. (peertechzpublications.org)
  • 19120-RT Excision of cyst, fibroadenoma, or other benign or malignant tumor, aberrant breast tissue, duct lesion, nipple or areolar lesion (except 19300), open, male or female, 1 or more lesions (90 global days). (aapc.com)
  • Rhabdomyoma is a lesion of striated muscle. (medscape.com)
  • Chromosomes of the neoplasm were studied by the fluorescence in situ hybridization technique and the tumor was found to carry XX chromosomes. (biomedcentral.com)
  • Desmoid tumor classified as deep fibromatoses , a type of benign myofibroblastic neoplasm originating from the muscle aponeurosis(1). (iomcworld.com)
  • Sarcomas are rare tumours that arise from mesenchymal tissues and comprise 1% of all adult solid cancers [ 1 ]. (oncotarget.com)
  • Though LMS may arise from any site in the body containing a smooth muscle layer, they most often occur in the uterus, the retroperitoneum, and the extremities [ 5 , 6 ]. (oncotarget.com)
  • and lymphoma, a solid neoplasm that originates in the lymphocytes -- a type of white blood cell in the bloodstream. (petmd.com)
  • Normally, the pressure in the pulmonary arteries is low, allowing the right side of the heart to be less muscular than the left side (because relatively little muscle and effort are needed to push the blood through the lungs via the pulmonary arteries). (msdmanuals.com)
  • It accounts for only 0.8 to 1% of all cancers and represents 1 to 1.8% of superficial soft tissue sarcomas. (thieme-connect.de)
  • Deposits of IgM, IgG and the third complement component are detected in the walls of the blood vessels of skeletal muscles. (symptoms.tips)
  • The arrector pili muscle contracts in response to cold, most commonly, or to fear or pleasure, causing what is commonly known as goose bumps. (medscape.com)
  • New abnormal growth of tissue. (lookformedical.com)
  • Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. (lookformedical.com)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
  • Primary LMSs rarely occur in the oral and maxillofacial region, probably due to paucity of smooth muscle tissue in the area [1,3]. (peertechzpublications.org)
  • whether the tumor is a primary placental or uterine neoplasm. (biomedcentral.com)
  • A new technique has been presented that results in an acceleration of delayed primary healing with full thickness skin and subcutaneous tissue coverage. (who.int)
  • Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. (lookformedical.com)
  • By means of phagocytosis the capsules got into the MSC, and after that the cells were treated with infrared light that penetrates the tissues deeply without damaging them. (news-medical.net)
  • Source of smooth muscle in the oral cavity may be the arterial tunica media, lingual duct, circumvallate papillae and pluripotential mesenchymal cells [1]. (peertechzpublications.org)
  • Histologically, the nodule was composed of bundles of smooth muscle cells. (biomedcentral.com)
  • C3H/He mice were anesthetized and implanted with osteolytic NCTC clone 2472 cells into the humeri or injected with 4% carrageenan into the triceps muscles of both forelimbs. (umn.edu)
  • The histopathology of adult rhabdomyoma is characterized by the presence of well-differentiated large cells that resemble striated muscle cells. (medscape.com)
  • The histopathology of fetal rhabdomyoma reveals the presence of a mixture of spindle-shaped cells with indistinct cytoplasm and muscle fibers, which resemble striated muscle tissue observed in intrauterine development at 7-12 weeks. (medscape.com)
  • The pituitary gland produces thyroid stimulating hormone (TSH) that goes into the blood stream to activate thyroid cells, which then secrete T3 and T4 into the peripheral tissues. (cdc.gov)
  • however, some authors believe it may be solely due to contraction of muscle fibers. (medscape.com)
  • Model parameters in liver and neoplasm were not significantly different, and glucose transport and phosphorylation were twofold and fourfold greater than in muscle. (jci.org)
  • The additional 32 micrograms is the result of T4 to T3 conversion by the deiodinase enzyme, located in almost all tissues of the body, mainly the liver. (cdc.gov)
  • Dermatofibrosarcoma protuberans (DFSP) is an uncommon, painless, slow-growth, superficial soft tissue malignant sarcoma corresponding to less than 0.1% of all malignancies. (thieme-connect.de)
  • Dermatofibrosarcoma protuberans (DFSP) is a rare superficial and uncommon low-grade soft tissue malignant sarcoma that is locally invasive and often characterized as a keloid sarcoma. (thieme-connect.de)
  • Neoplasms of the placenta are uncommon. (biomedcentral.com)
  • Journal of Cachexia, Sarcopenia and Muscle , 13 (2), 1289-1301. (nebraska.edu)
  • Tissue examination is necessary to establish the diagnosis. (medscape.com)
  • Molecular investigation of ALK-positive mesenchymal neoplasms could allow for an accurate diagnosis and personalized treatment. (yonsei.ac.kr)
  • These devices also have attachments for gathering samples of tissue and fluid, so that a biopsy can be performed to confirm the preemptive diagnosis. (petmd.com)
  • Neither CT nor MRI is tissue specific, and tissue diagnosis may be required. (medscape.com)
  • Ischiorectal fossa: benign and malignant neoplasms of this "ignored" radiological anatomical space. (beds.ac.uk)
  • Myoglobin is found in skeletal and cardiac muscle but not in smooth muscle. (celltechgen.com)
  • A leiomyoma is a relatively harmless and non-spreading tumor that arises from the smooth muscle of the stomach and intestinal tract. (petmd.com)
  • A rare benign smooth muscle neoplasm involving the placental parenchyma is presented. (biomedcentral.com)
  • A patient with a placental smooth muscle tumor that appears to be a uterine leiomyoma entrapped entirely in the placenta during its growth is presented. (biomedcentral.com)
  • This is a study of perioperative pembrolizumab or enfortumab vedotin in combination with pembrolizumab in participants who are cisplatin-ineligible or decline cisplatin with muscle-invasive bladder cancer (MIBC). (msdoncologyclinicaltrials.com)
  • MRI has shown potential for detection of muscle invasion but has not specifically been evaluated for this purpose in the setting of bladder cancer patients without evidence of muscle invasion on initial biopsy. (nyu.edu)
  • The radiologists identified whether cases suspicious for invasion demonstrated disruption of the T2-hypointense muscularis layer of the bladder wall, peri-vesical fat stranding, and peri-vesical soft tissue nodularity. (nyu.edu)
  • Conclusion: MRI demonstrated high sensitivity for detection of muscle invasion in cases of bladder cancer without invasion on initial histologic assessment. (nyu.edu)
  • This mouse line would be the best preclinical model to aid in clarifying molecular mediators of CAC and dissecting metabolic dysfunction and tissue atrophy during the progression of CAC. (nebraska.edu)
  • The tumor is usually circumscribed by a pseudocapsule formed of compressed renal and perirenal tissues. (abdominalkey.com)
  • Adult rhabdomyoma usually is localized to the oropharynx, the larynx, and the muscles of the neck. (medscape.com)
  • Some neoplasms appear more unique to the area, e.g., angiofibroma, while most can occur throughout the soft tissues of the entire body. (basicmedicalkey.com)
  • Results: Suspicion was raised for muscle invasion in eight of 23 cases, four of which exhibited invasion on follow-up pathology. (nyu.edu)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • Demographic, Clinical and Histopathological Features of Oral Neural Neoplasms: A Retrospective Study. (beds.ac.uk)
  • Histopathology demonstrated monomorphic fusiform cell neoplasm, in a "swirled" focal arrangement, infiltrative of dermal tissue, compatible with DFSP. (thieme-connect.de)
  • Immunoglobulin G4-related disease (IgG4-RD) is a chronic inflammatory disorder associated with fibrosis and abundant tissue lymphoplasmacytic infiltrations. (hindawi.com)
  • CT examination revealed well-defined, superficial masses with subcutaneous fat tissue infiltration. (thieme-connect.de)
  • The mass was suggested as a soft tissue tumor by computed tomographic (CT) examination. (thieme-connect.de)
  • Pathologic features were assessed by expert gastrointestinal and/or soft tissue pathologists at each center. (elsevierpure.com)
  • The histopathology report indicated both free soft (confirming the previous report) and hard tissue margins. (peertechzpublications.org)
  • The cut surface is typically solid, soft, and gray or pink, with a texture and appearance resembling brain tissue. (abdominalkey.com)
  • This is in contrast to other soft tissue sarcomas in which the lung is the most common site of metastasis. (medscape.com)