Tissue injury severity score. Medical search. Frequent questions

Sometimes bruises can be serious, leading to other more life-threatening forms of hematoma, such as when associated with serious injuries, including fractures and more severe internal bleeding. (wikipedia.org)
As the mothers pelvis becomes more lax during the course of her pregnancy, trauma can result in pelvic fractures as one of the more common injuries sustained through blunt trauma. (adlergiersch.com)
The impact of a dedicated orthoplastic operating list on time to soft tissue coverage of open lower limb fractures. (ox.ac.uk)
In a penetrating head injury, an object such as a bullet fractures the skull and enters brain tissue. (encyclopedia.com)
Although many authors use the term brain injury to mean acute traumatic damage to the central nervous system (CNS), others use the term head injury, which allows inclusion of skull injuries, fractures, or soft tissue damage to the face or head without any obvious neurologic consequences. (medscape.com)
Common complications for open reduction internal fixation (ORIF) of humeral shaft fractures include radial nerve injury, infection, and hardware failure 3 . (researchsquare.com)
Given the severity of open fractures, maximizing the effectiveness of current prophylactic procedures is essential. (biomedcentral.com)
The incidence of MCC upper extremity injury was 47.5%, with hand and forearm fractures the most common injuries (25.5% and 24.7% of total injuries). (sicot-j.org)

A broader definition of ecchymosis is the escape of blood into the tissues from ruptured blood vessels. (wikipedia.org)
Bruise colors vary from red, blue, or almost black, depending on the severity of broken capillaries or blood vessels within the bruise site. (wikipedia.org)
When the skull cracks or breaks, the resulting skull fracture can cause a contusion, or an area of bruising of brain tissue associated with swelling and blood leaking from broken blood vessels. (encyclopedia.com)

The alcohol group had a higher incidence of head injuries (46 (48%) versus 22 (9%)) with a lower incidence of limb injuries (39 (39%) versus 183 (76%)) than the no alcohol group. (bmj.com)
Traumatic brain injury (TBI) is the leading cause of death and disability in children and young adults around the world (Thurman et al 1999), with an incidence ranging from 108 to 392 per 100,000 population (Abelson-Mitchell 2008). (australian.physio)
The incidence of secondary overtriage in our rural trauma center is 26.4%, with head and neck injuries the most common reason for transfer. (nesurgical.org)
This is the first study to report the effectiveness of a single PRP injection in ankle syndesmosis injuries for Rugby Union players, who appear to have a high incidence of this injury. (bmj.com)
Several studies 1-3 have suggested that these injuries have a higher incidence than once thought, and are probably underdiagnosed. (bmj.com)
Despite vital protection for the brain and maxillofacial injury, helmeted MCC patients have an increased incidence of upper extremity injuries compared to non-helmeted patients, but overall have less severe injuries. (sicot-j.org)

The most common type and mechanism of injury was single fracture injury and fall less than 2m respectively. (pediatriconcall.com)
[2] While blunt trauma is by far the most common mechanism of maternal injury, 50%-70% of blunt trauma among pregnant patients is attributed to motor vehicle collisions. (adlergiersch.com)
Consequences of TBI can be relatively subtle or completely devastating, related to the severity and mechanism of injury. (encyclopedia.com)
Structural changes from head injury may be gross or microscopic, depending on the mechanism and forces involved. (msdmanuals.com)

The severity of both limb and head injury is greater and correlates directly with blood alcohol concentration. (bmj.com)
This study aimed to report the limb salvage outcomes in patients requiring multiple flap procedures for two or more concurrent extremity injuries. (usuhs.edu)
A retrospective cohort comparison of warfare-related extremity injuries treated for limb salvage from 2003 through 2012 at the National Capital Consortium was completed. (usuhs.edu)
Number of single and multiple flap limb salvages, Injury Severity Score, success rates, and complications were analyzed. (usuhs.edu)
Limb salvage requiring multiple flap procedures in the polyextremity-injured patent is safe and equally effective when compared with a single-limb-injured cohort despite a significantly higher injury severity score. (usuhs.edu)
Occasionally, an injury or condition that does not directly affect the vasculature has disabled the upper extremity to the extent that a prosthesis would be functionally superior to sparing the limb. (medscape.com)
Occasionally, the injury is so severe that the limb cannot be saved, and amputation is necessary. (thetraumapro.com)

See Pediatric Concussion and Other Traumatic Brain Injuries , a Critical Images slideshow, to help identify the signs and symptoms of TBI, determine the type and severity of injury, and initiate appropriate treatment. (medscape.com)
Serious traumatic brain injuries need emergency treatment. (rxwiki.com)

Even though these are intended to temporarily incapacitate individuals, it is often encountered that kinetic impact projectiles can cause penetration, severe injuries, permanent disabilities and even mortality. (journaltocs.ac.uk)
For those with more severe injuries, loss of consciousness (LOC) occurs at the time of trauma, lasting from a few minutes or hours to several weeks or even months. (brainline.org)
People with severe injuries usually need rehabilitation. (rxwiki.com)
Patients with less severe injuries may have no gross structural damage. (msdmanuals.com)

Assessing outcomes objectively is challenging, but the evolution of injury severity scoring systems with sufficient precision and reproducibility now permits trauma centers to compare their processes and outcomes, facilitating identification of best practices that form the foundations of quality improvement programs. (medscape.com)
The hip functional outcomes were assessed with the Harris hip score (HHS). (bvsalud.org)
[4] Aside from injuries to the pregnant patient herself, the likelihood of miscarriage, early labor, premature rupture of membranes, abruption, [5] and fetal demise are possible medical outcomes for the fetus. (adlergiersch.com)
An earlier study conducted in the state of Washington between 1989-1997 reviewed all post-trauma hospital admissions and sought to distinguish patient outcomes between those with major and minor injuries. (adlergiersch.com)
The study ultimately concluded that women hospitalized after a motor vehicle collision are indeed at an increased risk for adverse pregnancy outcomes regardless of the presence or absence of identifiable physical injuries. (adlergiersch.com)
Patient outcomes following a minor polytrauma are often worse than those with a single severe injury. (medsci.org)
Further, gender differences in societal expectations of self-care after injury and the rate of recovery may potentiate negative patient outcomes for men. (asbmb.org)
Blast injury emerged as a primary source of morbidity among US military personnel during the recent conflicts in Iraq and Afghanistan, and led to an array of adverse health outcomes. (biomedcentral.com)
Differences in individual alveolar or bronchiolar outcomes and severity correlated with physical dimensions and how the materials agglomerated. (cdc.gov)
Particles of greater nominal tube length were generally associated with increased severity of histopathology outcomes. (cdc.gov)

Advances in combat casualty care, medical transport, and personal protective equipment led to a greater survivability from wounds, and the US Military Health System subsequently faced a growing number of service members and veterans with injury-related sequelae [ 3 ]. (biomedcentral.com)

[ 1 ] Contusions are formed in 2 ways: direct trauma and acceleration/deceleration injury. (medscape.com)

In the first few days after the injury, maintaining adequate brain perfusion and oxygenation and preventing complications of altered sensorium are important. (msdmanuals.com)

Diffuse axonal injury, or shear injury, may follow contrecoup injury even if there is no damage to the skull or obvious bleeding into the brain tissue. (encyclopedia.com)
The results of a closed head injury tend to affect broad areas of the individual's functioning, primarily due to the diffuse axonal injury . (brainline.org)

[9] (Patients with an Injury Severity Score or ISS [10] greater than 9 were considered to be severely injured. (adlergiersch.com)

Amputation of a hand because of tissue necrosis. (medscape.com)
Hemorrhage within the contusion can result in ischemia and edema, which can progress to tissue destruction, necrosis of neuronal structures, and cavitation with overlying reactive gliosis. (medscape.com)

However, trauma mortality prediction in individual patients by any scoring system is limited and is in general no better than good clinical judgment. (medscape.com)
Traumatic brain injury (TBI), also known as acquired brain injury, head injury, or brain injury, causes substantial disability and mortality. (medscape.com)
Acute respiratory distress syndrome (ARDS) is a life-threatening, high mortality pulmonary condition characterized by acute lung injury (ALI) resulting in diffuse alveolar damage. (lu.se)
Moreover, motor vehicle collisions also remain one of the leading causes of both maternal and fetal mortality, with an estimated mortality rate ranging from a 1.4 per 100,000 to 3.7 point seven per 100,000 pregnancies, even though direct fetal injury occurs less than one percent of the time. (adlergiersch.com)
Background: Traumatic brain injury (TBI) is a serious hazard to human health and is characterized by high rates of disability and mortality. (aging-us.com)
Therefore, even with the increased risk of injury helmets may expose to the upper extremity, helmets reduced overall morbidity and mortality. (sicot-j.org)

Upper extremity injuries following motorcycle crashes (MCC) incur increased healthcare costs and rehabilitation needs. (sicot-j.org)
We aim to characterize the epidemiology of MCC upper extremity injuries and identify factors that influence the severity of and cost of care for upper extremity injuries. (sicot-j.org)
We performed a retrospective cohort analysis of 571 patients with upper extremity injuries after MCC at a level 1 trauma center from 2002 to 2013. (sicot-j.org)
Upper extremity injuries are common in motorcyclists. (sicot-j.org)
In addition to mandatory helmet laws, we advocate for further development of safety equipment focusing specifically on the prevention of upper extremity injuries. (sicot-j.org)

For example, coup-contrecoup injury may occur in a rear-end collision, with high speed stops, or with violent shaking of a baby, because the brain and skull are of different densities, and therefore travel at different speeds. (encyclopedia.com)
As such, the radiographic findings are usually associated with underlying brain contusions, although significant brain injury may occur without these findings. (medscape.com)
it may also occur as a war injury. (wikipedia.org)
In sum, after a closed head injury, damage can occur both in specific brain areas (due to bruising and bleeding) and also be found throughout the brain (due to stretched or destroyed axons). (brainline.org)
As an individual regains consciousness (those with the severest injuries may never do so), a variety of neurologically based symptoms may occur: irritability, aggression and other problems. (brainline.org)
Doctors refer to injuries that do not occur at or around the time of birth and are not genetic or degenerative as an acquired brain injury. (asbmb.org)
Closed head injuries typically occur when the head is struck, strikes an object, or is shaken violently, causing rapid brain acceleration and deceleration. (msdmanuals.com)
Chronic Traumatic Encephalopathy (CTE) Chronic traumatic encephalopathy (CTE) is a progressive degenerative brain disorder that may occur after repetitive head trauma or blast injuries. (msdmanuals.com)

The ability to predict survival after trauma is perhaps the most fundamental use of injury severity scoring, Furthermore, injury severity scoring can provide objective correlations with resource utiliziation such as length of stay and costs of treatment, as well as inform clinical decisions regarding management of injuries of specific severity. (medscape.com)
Injury severity scoring is indispensable in stratifying patients into comparable groups for prospective clinical trials. (medscape.com)
The study is noteworthy in that it revealed that women classified as sustaining "minor injuries" nonetheless show an increased risk of abruption, infant hypoxia, and fetal death when compared to uninjured women, thus underscoring the clinical distinction between any degree of traumatic insult and the absence of trauma during pregnancy. (adlergiersch.com)
There are several clinical classifications for brain injuries. (asbmb.org)
A TBI can cause brain-cell death and tissue degeneration, potentially leading to many negative clinical symptoms for the patient, depending on the severity of the injury. (asbmb.org)
A total of 1972 US military personnel who sustained a blast-related injury during military operations in Iraq and Afghanistan were identified from clinical records. (biomedcentral.com)
Clinical manifestations vary markedly in severity and consequences. (msdmanuals.com)

Special regard in the examination was given to Glasgow coma scale, a precise anatomical description of injuries, results of investigations and treatment were recorded. (bmj.com)
TBIs may be closed or open injuries and are categorized on the basis of severity as measured by the Glasgow Coma Scale score (GCS). (medscape.com)
A 15-point test, called the Glasgow Coma Scale, helps a doctor or other emergency medical personnel assess the initial severity of a brain injury by checking a person's ability to follow directions and move their eyes and limbs. (rxwiki.com)
Doctors determine the severity of the injury using the Glasgow coma scale , which examines motor response, verbal ability and eye opening - ranking patient responses with a total score between 3 and 15. (asbmb.org)

It is important to remember that no injury severity score exists as a guide for severe upper-extremity trauma. (medscape.com)
An indication for amputation after nerve injury is the development of uncontrolled trophic ulcers in an anesthetic upper extremity. (medscape.com)
Intoxicated patients were more likely to have a high cost of care ( p = 0.012), extended LOS ( p = 0.038), plastic surgery involvement in their care ( p = 0.038), but fewer upper extremity bony injuries ( p = 0.019). (sicot-j.org)
Intoxicated patients have fewer upper extremity bony injuries, but the higher cost of care, and extended LOS. (sicot-j.org)

Severe peripheral vascular disease, traumatic injury, thermal and electrical injury, and frostbite commonly require amputation. (medscape.com)
Brain contusions commonly are identified in patients with traumatic brain injury (TBI) and represent regions of primary neuronal and vascular injury. (medscape.com)
15 - 18 The source images from the CT angiography (CTA) vascular acquisition provide clinically relevant data concerning tissue perfusion level. (ajnr.org)

The goal of management is early recognition in order to restore tissue perfusion and thereby prevent progression to multisystem organ failure and death. (medscape.com)

An UCCAO caused a slight cerebral ischemia (cerebral blood flow [CBF] 70%) without hypotension (MABP 85 mmHg), systemic inflammation, multiple organs injuries, or neurological injury. (medsci.org)
An HS caused a moderate cerebral ischemia (52% of the original CBF levels), a moderate hypotension (MABP downed to 22 mmHg), systemic inflammation, and peripheral organs injuries. (medsci.org)
However, combined an UCCAO and an HS caused a severe cerebral ischemia (18% of the original CBF levels), a moderate hypotension (MABP downed to 17 mmHg), systemic inflammation, peripheral organs damage, and neurological injury, which can be attenuated by whole body cooling. (medsci.org)

When combined with an HS, an UCCAO is associated with ischemic neuronal injury in the ipsilateral hemisphere of adult rat brain, which can be attenuated by therapeutic hypothermia. (medsci.org)

Similarly, this technique can be used retrospectively to identify and control for differences in baseline injury severity between patient populations. (medscape.com)

Surgery is often needed in patients with more severe injury to place monitors to track and treat intracranial pressure elevation, decompress the brain if intracranial pressure is increased, or remove intracranial hematomas. (msdmanuals.com)

Especially, pulmonary administration of PSLipos-L-NAC could significantly reduce the inflammatory response of M1-like macrophages in lung tissue and promote lung injury repair in a bleomycin-induced acute lung injury (ALI) mouse model, providing a potential therapeutic approach for ALI. (biomedcentral.com)
The TNF-α pathway is commonly upregulated in acute lung injury (ALI) and acute liver failure (ALF). (sinica.edu.tw)

Although, decisions for individual patients should never be based solely on a statistically derived injury severity score, scoring systems can nonetheless serve to estimate quantitatively the level of acuity of injured patients that are applied to adjustments in hospital outcome assessments. (medscape.com)

Diffuse brain damage associated with closed head injury may result from back-and-forth movement of the brain against the inside of the bony skull. (encyclopedia.com)
The impact of the collision causes the soft, gelatinous brain tissue to jar against bony prominences on the inside of the skull. (encyclopedia.com)
In closed head injury, damage occurs because the person receives a blow to the head that whips the head forward and back or from side to side (as in a car crash), causing the brain to collide at high velocity with the bony skull in which it is housed. (brainline.org)

By definition, TBI requires that there be a head injury, or any physical assault to the head leading to injury of the scalp, skull, or brain. (encyclopedia.com)
Open head injuries involve penetration of the scalp and skull (and usually the meninges and underlying brain tissue). (msdmanuals.com)

Either of these types of skull fracture can cause bruising of the brain tissue, called a contusion. (encyclopedia.com)

18.6% of injuries sustained by children assessed as PMT were soft tissue injuries suggesting patients are being over-triaged. (pediatriconcall.com)
Among patients with the most severe grades of injury (Gustilo types IIIB and IIIC), there was a trend towards an improved time to first skeletal stabilisation (29.5 vs 14.2 hours, p=0.068), an improvement in time to soft tissue coverage (173.6 vs 88.1 hours, p=0.009) and a trend towards a reduced length of inpatient stay (32.6 vs 23.2 days, p=0.138). (ox.ac.uk)
In 1764, Baurienne originally described an idiopathic, rapidly progressive soft-tissue necrotizing process that led to gangrene of the male genitalia. (medscape.com)

There are three levels of TBI severity: mild, moderate and severe. (asbmb.org)

Minor bruises may be easily recognized in people with light skin color by characteristic blue or purple appearance (idiomatically described as "black and blue") in the days following the injury. (wikipedia.org)
Dr. Kolodenker treats a variety of common and rare conditions of the foot and ankle, including injuries (minor as well as severe trauma), general foot pain, heel pain, hammertoes, bunions, flat feet, plantar fasciitis, and neuromas. (insighthack.com)
In common parlance, concussion may refer to any minor injury to the head or brain. (encyclopedia.com)

Injuries are commonly categorized as open or closed. (msdmanuals.com)

Bruises which do not blanch under pressure can involve capillaries at the level of skin, subcutaneous tissue, muscle, or bone. (wikipedia.org)

Review of the literature demonstrated a Finnish study by Honkanen 1 and an American study by Hingson 2 investigating alcohol related falls although there has been more research on the effect of alcohol on general brain injury. (bmj.com)
Pediatric trauma patients with brain injury, central venous catheters, immobilization, or surgical procedures are at highest risk for developing a deep venous thrombosis. (uzh.ch)
This glossary provides information and definitions of medical terms associated with brain injury and rehabilitation to help you or your family. (brainline.org)
acquired brain injury - the implication of this term is that the individual experienced normal growth and development from conception through birth, until sustaining an insult to the brain at some later time which resulted in impairment of brain function. (brainline.org)
This study aimed to investigate whether resuscitation after a hemorrhagic shock (HS) and/or mild cerebral ischemia caused by a unilateral common carotid artery occlusion (UCCAO) can cause brain injury and concomitant neurological dysfunction, and explore the potential mechanisms. (medsci.org)
Traumatic brain injury (TBI) is the result of physical trauma to the head causing damage to the brain. (encyclopedia.com)
TBI is sometimes known as acquired brain injury. (encyclopedia.com)
Symptoms, complaints, and neurological or behavioral changes following TBI depend on the location (s) of the brain injury and on the total volume of injured brain. (encyclopedia.com)
Usually, TBI causes focal brain injury involving a single area of the brain where the head is struck or where an object such as a bullet enters the brain. (encyclopedia.com)
Although damage is typically worst at the point of direct impact or entry, TBI may also cause diffuse brain injury involving several other brain regions. (encyclopedia.com)
Coup," or French for "blow," refers to the brain injury directly under the point of maximum impact to the skull. (encyclopedia.com)
Contrecoup," or French for "against the blow," refers to the brain injury opposite the point of maximum impact. (encyclopedia.com)
Huang L , Kang J , Chen G , Ye W , Meng X , Du Q , Feng Z , . Low-intensity focused ultrasound attenuates early traumatic brain injury by OX-A/NF-κB/NLRP3 signaling pathway. (aging-us.com)
Traumatic brain injury (TBI) remains a major global public health problem [ 1 ]. (aging-us.com)
Brain injury often results in various physical and mental sequelae, such as epilepsy, chronic encephalopathy, and depression [ 2 ], which cause great harm to sufferers and have a tremendous economic impact on families and the social health system. (aging-us.com)
Brain injury is often defined differently in published reports. (medscape.com)
Skull radiographs are notoriously unhelpful in predicting underlying brain injury. (medscape.com)
This case study shows the benefit of long- term physical rehabilitation in reducing activity limitations and enhancing participation levels in an individual with chronic traumatic brain injury-related mobility deficits. (australian.physio)
Evidence indicates that brain injury is a dynamic condition that changes over time (Corrigan & Hammond 2013). (australian.physio)
Rather than being static, brain injury can evolve into a lifelong health condition, chronic brain injury (CBI) (Hammond & Malec 2013). (australian.physio)
Below is a glossary of important terms that can help you better understand traumatic brain injury. (casperdetoledo.com)
If you have questions or concerns about a case, please contact a Connecticut brain injury lawyer from Casper & de Toledo, LLC. (casperdetoledo.com)
Traumatic brain injury (TBI) refers to damage or destruction of brain tissue due to a blow to the head, resulting from an assault, a car crash, a gunshot wound, a fall, or the like. (brainline.org)
Traumatic brain injury (TBI) happens when a sudden trauma causes damage to the brain. (rxwiki.com)
Traumatic brain injury (TBI) is a form of acquired brain injury that occurs when a sudden trauma causes damage to the brain. (rxwiki.com)
March is Brain Injury Awareness Month, a time to bring public attention to an issue affecting millions of people in the U.S. every year. (asbmb.org)
The Brain Injury Association of America leads this campaign with the purpose of destigmatizing brain injury, empowering those who have survived a brain injury, and promoting the many types of support available. (asbmb.org)
According to the BIAA , a person in the U.S. sustains a brain injury every nine seconds, culminating in more than 3.5 million injuries each year. (asbmb.org)
An ABI can be either a nontraumatic or a traumatic brain injury , depending on the injury's inciting source. (asbmb.org)
Falls are a major cause of brain injury, resulting in 40.5% of all TBIs. (asbmb.org)
Traumatic brain injury (TBI) is physical injury to brain tissue that temporarily or permanently impairs brain function. (msdmanuals.com)
Sports-Related Concussion Sports activities are a common cause of concussion, a form of mild traumatic brain injury. (msdmanuals.com)

These lobes house major brain centers involved in speech and language, so problems with communication skills often follow closed head injuries of this type. (encyclopedia.com)
Damage following open head injuries tends to be focal, not diffuse, and the implications for subsequent impairment tend, also, to be focal and limited. (brainline.org)
However, such injuries can be as severe as closed head injuries, depending on the destructive path of the bullet or other invasive object within the brain. (brainline.org)

Abstract During the last decades, there has been an increase in the development and use of kinetic energy non-lethal projectiles, mainly because of their ability to neutralise without inflicting serious injuries. (journaltocs.ac.uk)
In such serious injuries, the first few days after trauma may also produce negative changes in respiration (breathing) and motor functions. (brainline.org)

The least severe and most common type of TBI is termed a concussion, which is technically defined as a brief loss of consciousness after a head injury without any physical evidence of damage on an imaging study such as a CT or MRI scan. (encyclopedia.com)

Conclusions This pilot study shows that, following ankle syndesmosis injury, a single autologous PRP injection may accelerate safe and successful return to Rugby Union, with improved functional capacity and reduced fear avoidance. (bmj.com)

In 1969, researchers developed the Abbreviated Injury Scale (AIS) to grade the severity of individual injuries. (medscape.com)
A systematic history and examination permitted calculation of injury severity scores as per abbreviated injury scale update 1998. (bmj.com)
Also to assess the relationship in critically ill patients between: sequential organ failure assessment (SOFA) score, Braden Scale score for predicting pressure injury risk, Acute Physiology and Chronic Health Evaluation II (APACHE II) severity of disease classification score, and IP and TR. (hud.ac.uk)
A mild TBI lands on the higher side of the scale, whereas a severe TBI results in a lower score. (asbmb.org)
Admission National Institutes of Health Stroke Scale (NIHSS) score, onset-to-imaging time, CTA-SI Alberta Stroke Program Early CT Score, MCA M1 occlusion, cerebrovascular collaterals score, and CTA-SI lesion volume were correlated with 3- to 6-month follow-up modified Rankin Scale (mRS). We developed 2 stepwise regression models: one for patients with complete MCA M1 recanalization and one for patients without complete recanalization. (ajnr.org)
All of the patients were referred for imaging by a stroke neurologist who determined an initial National Institutes of Health Stroke Scale (NIHSS) score. (ajnr.org)

Symptoms of a TBI may not appear until days or weeks following the injury. (rxwiki.com)
Depressive ( P = 0.002) and anxiety ( P = 0.003) symptoms were associated with a poor global Pittsburgh Sleep Quality Index score among recovered female participants ( P = 0,034) who had low-to-medium education level ( P = 0.004). (who.int)

apoptosis - cell death that occurs naturally as part of normal development, maintenance, and renewal of tissues within an organism. (brainline.org)
The combination of injuries often occurs in modern warfare and automobile and industrial accidents [ 13 - 15 ]. (medsci.org)
Open head injury, the second type of TBI, occurs when the skull is penetrated, for example by a bullet. (brainline.org)
There is usually primary spinal cord injury (SCI) that occurs within minutes of the original insult. (medscape.com)

However, one of the main challenges in using large animal models of preclinical research is that fewer species-specific experimental tools and metrics are available for evaluating the extent of lung injury, as compared to rodent models. (lu.se)
In the mouse ALI model, aptTNF-α/aptTNF-α-PEG treatment attenuated the severity of LPS-induced ALI, as indicated by the improvement of oxygen saturation and lung injury scores, the reduction of protein-rich fluid leakage and neutrophil infiltration in the alveolar spaces, and the suppression of pro-inflammatory cytokines/chemokines expressions in the lung tissues. (sinica.edu.tw)

Abstract To effectively assess the injury risk of the blunt impact of the SIR-X sponge grenade on the human thorax, in this paper, we used a numerical simulation technique to test the non-lethal kinetic energy projectiles that blunt impact on the Hybrid III 50th dummy model. (journaltocs.ac.uk)
abstract = "BACKGROUND: Trauma patients with high-energy injuries often present with severe tissue damage that extends beyond the immediate zone of injury and requires recruitment of vascularized tissues from distant sites. (johnshopkins.edu)

As a type of hematoma, a bruise is always caused by internal bleeding into the interstitial tissues which does not break through the skin, usually initiated by blunt trauma, which causes damage through physical compression and deceleration forces. (wikipedia.org)
Hemorrhage from pelvic fracture is common in victims of blunt traumatic injury. (east.org)
The study aimed to estimate the association between thoracic injury severity as evaluated by computed tomography (CT) and arterial blood gas and acid base status in dogs sustaining natural, blunt trauma. (vin.com)
They typically involve bullets or sharp objects, but a skull fracture with overlying laceration due to severe blunt force is also considered an open injury. (msdmanuals.com)

Maternal and fetal deaths were found to be highest with injuries to the mother's pelvis, abdomen, and thorax. (adlergiersch.com)
Thorax injuries were classified as pleural space, rib cage or pulmonary and each of these three components of the thorax were scored according to severity. (vin.com)

MRI findings typically demonstrate the lesions from the onset of injury, but many facilities cannot perform MRI on an emergent basis. (medscape.com)
Typically, "severity of injury" refers to the degree of brain tissue damage. (brainline.org)

Note the acute inflammatory cells in the necrotic tissue. (medscape.com)

Trauma scoring also is used for quality assurance by allowing evaluation of trauma care both within and between trauma centers, a contentious and controversial area that is likely to only increase in importance. (medscape.com)

The median Index Severity Score for TARN patients was 9. (pediatriconcall.com)
The Saudi cohort was younger, the median age being 36 years compared with 50 years, with 51% of injuries caused by road traffic incidents. (bmj.com)

Results: LIFUS improved tissue damage, neurological deficits, and brain edema. (aging-us.com)

Therefore, semi-quantitative histological scoring systems designed to evaluate tissue-level injury in large animal models of ALI/ARDS are needed. (lu.se)

A bruise, also known as a contusion, is a type of hematoma of tissue, the most common cause being capillaries damaged by trauma, causing localized bleeding that extravasates into the surrounding interstitial tissues. (wikipedia.org)
The likelihood and severity of bruising depends on many factors, including type and healthiness of affected tissues. (wikipedia.org)
Histological injury in these models differs due to the type and severity of the injury being modeled. (lu.se)
Participant type, body mass index (BMI), Braden and APACHE II scores and patient body temperature were considered as between-groups factors and covariates. (hud.ac.uk)
In this type of injury, damage to the part of the nerve that communicates with other nerves degenerates and releases harmful substances that can damage neighboring nerves. (encyclopedia.com)
the frontal and temporal lobes are particularly vulnerable to this type of injury. (msdmanuals.com)

Results Groups were comparable in anthropometrics, playing position and MRI injury severity. (bmj.com)
Their results showed therapeutic promise, with observed reductions in cell death and tissue degeneration when silencing calpain-1. (asbmb.org)
Neurogenic shock, another form of distributive shock, usually results from a cervical or high thoracic spine injury (above T6) leading to the sudden loss of sympathetic tone. (medscape.com)

The pCO 2 was not significantly different from any of the thoracic injury variables indicating normal alveolar ventilation. (vin.com)
Spherical agglomerated particles of smaller nominal tube dimension were linked to granulomatous inflammation while a mixture of smaller and larger dimensional CNT/F resulted in more severe alveolar injury. (cdc.gov)

Closed head injury refers to TBI in which the head is hit by or strikes an object without breaking the skull. (encyclopedia.com)
In a penetrating skull fracture, bone fragments enter brain tissue. (encyclopedia.com)
TBI can result when the head suddenly and violently hits an object or when an object pierces the skull and enters brain tissue. (rxwiki.com)

Anatomy2

Organisms2

Diseases42

Chemicals and Drugs1

Analytical, Diagnostic and Therapeutic Techniques and Equipment51

Phenomena and Processes5

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture7

Humanities2

Information Science11

Named Groups2

Health Care51

Geographicals4

Fractures8

Blood vessels3

Incidence6

Mechanism4

Limb7

Traumatic Brain In2

Severe injuries4

Outcomes10

Wounds1

Acceleration-deceleration1

Complications1

Diffuse axonal2

Patients with an Injury Sever1

Necrosis2

Mortality6

Extremity injuries5

Occur8

Clinical7

Glasgow Coma4

Upper-extremity4

Vascular3

Perfusion1

Hypotension3

Hypothermia1

Patient populations1

Hematomas1

Acute lung i2

Statistically1

Bony3

Scalp2

Bruising of the brain tissue1

Soft3

Moderate1

Minor3

Commonly1

Bruises1

Brain injury32

Head injuries3

Serious injuries2

Concussion1

Conclusions1

Scale6

Symptoms2

Occurs4

Lung injury2

Abstract2

Blunt4

Thorax2

Typically2

Necrotic1

Trauma centers1

Median2

Deficits1

Designed to evaluate1

Type6

Results3

Alveolar2

Skull3