• bite
  • Ehrlichiosis anaplasmosis (formerly human granulocytic ehrlichiosis or HGE) Organism: Ehrlichia chaffeensis, E. equi (renamed to Anaplasma phagocytophilum, see Human granulocytic anaplasmosis for another example) Vector: Lone star tick (Amblyomma americanum), I. scapularis Region (US): South Atlantic, South-central Bartonella: Bartonella transmission rates to humans via tick bite are not well established but Bartonella is common in ticks. (wikipedia.org)
  • Immediately upon the onset of a tick bite, it transmits a pain killer, anti-histamine and an anti-coagulant. (lymebook.com)
  • The illness follows a lone star tick bite, and clinically resembles Lyme disease, but sufferers usually test negative for Lyme. (wikipedia.org)
  • The recently discovered B miyamotoi species is transmitted by tick bite and may be transmissible via blood transfusion. (medscape.com)
  • Alzheimer's
  • We and others have examined patients with various neurodegenerative and behavioral neurological conditions, such as Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Alzheimer's disease (AD) and Autistic Spectrum Disorders ([ASD], including Autism, Attention Deficit Disorder, Asperger Syndrome), and found evidence for systemic intracellular bacterial and viral infections in a majority of patients. (townsendletter.com)
  • Endemic
  • Lyme disease is most endemic in Northern Hemisphere temperate regions, but sporadic cases have been described in other areas of the world. (wikipedia.org)
  • This might be due to the very low incidence in an endemic region (0.2%, CI 95% 0.0% to 1.1%) as demonstrated in 517 patients hospitalized for psychiatric diseases. (blogspot.com)
  • neurological
  • 1-5 One of the biochemical changes found in essentially all neurological degenerative diseases is the over-expression of oxidative free radical compounds (oxidative stress) that cause lipid, protein, and genetic structural changes. (townsendletter.com)
  • An attractive model for neurodegeneration resulting in neurological disease involves the action of toxic products produced as a result of chronic bacterial and/or viral infections. (townsendletter.com)
  • Can microbes and immune reactions to them actually contribute to cognitive decline, degenerative neurological disease, developmental disabilities, mental illness, personality changes and, at the most extreme, even violent and criminal behavior? (psychologytoday.com)
  • Although most patients with Lyme/tick-borne disease do not become violent, a small percent of patients who become infected develop a type of neurological dysfunction that can increase their risk of aggressiveness. (psychologytoday.com)
  • ALS is a motor neuron disease, also spelled "motor neurone disease", which is a group of neurological disorders that selectively affect motor neurons, the cells that control voluntary muscles of the body, including amyotrophic lateral sclerosis (ALS), primary lateral sclerosis, progressive muscular atrophy, progressive bulbar palsy, pseudobulbar palsy, and spinal muscular atrophy. (wikipedia.org)
  • systemic
  • Patients with neurodegenerative diseases and behavioral disorders often have systemic bacterial, viral, and/or fungal infections that are important in disease progression and severity. (townsendletter.com)
  • In the first part of this review we considered neurodegenerative and neurobehavioural diseases and the findings that these diseases commonly are associated with systemic and central nervous system bacterial and viral infections. (blogspot.com)
  • However, about 10-15% of patients with Lyme arthritis fail the initial course of antibiotics, and some of those develop a chronic inflammatory arthritis optimally treated with local or systemic immunosuppressive agents. (springer.com)
  • antibiotics
  • In the US, neuroborreliosis is typically treated with intravenous antibiotics which cross the blood-brain barrier, such as penicillins, ceftriaxone, or cefotaxime. (wikipedia.org)
  • 11 In contrast, if the SF-36 was used to determine Quality of Life (QOL) in post-Lyme patients, the average SF-36 physical component summary (40±9, range 29-44) and mental component summary (39±14, range 23-46) of the QOL assessment were worse than the general USA population, and they could be significantly improved by anti-Lyme antibiotics (46% versus 18%, p =0.007). (blogspot.com)
  • His clinical work has involved advising upon infectious disease for cardiac transplant patients, advising on antibiotics and their use, teaching at the University of North Carolina at Chapel Hill and becoming involved in clinical research associated with these fields. (lymediseaseaction.org.uk)
  • The doctor rashly (pun intended) diagnosed Lyme's disease (I'd also been feasted upon by four ticks in the previous 2 weeks) and put me on antibiotics. (blogspot.de)
  • infections
  • 1 In addition to genetic changes and changes in gene expression, it is thought that nutritional deficiencies, head trauma, environmental toxins, chronic bacterial and viral infections, autoimmune immunological responses, vascular diseases, accumulation of fluid in the brain, changes in neurotransmitter concentrations, and other causes are involved in various neurodegenerative diseases. (townsendletter.com)
  • B . hispanica and B . crocidurae infections have been detected in northern and southern Morocco, respectively, along with the tick vectors responsible for their transmission ( Ornithodoros erraticus and O . sonrai , respectively) ( 8 ). (cdc.gov)
  • 1 In this second part we continue with psychiatric diseases, autoimmune diseases, fatiguing illnesses, and other chronic diseases where chronic infections play an important role. (blogspot.com)
  • arthritis
  • It was first identified in 1975 in the town of Old Lyme, CT after an outbreak of juvenile rheumatoid arthritis. (davidson.edu)
  • Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three connecticut communities. (springer.com)
  • Orczyk K, Swidrowska-Jaros J, Smolewska E. When a patient suspected with juvenile idiopathic arthritis turns out to be diagnosed with an infectious disease - a review of Lyme arthritis in children. (springer.com)
  • bacterium
  • Transmission of the bacterium that causes Lyme disease is well understood to require a substantial feeding period. (wikipedia.org)
  • This is because OspA allows the bacterium to adhere to the gut of the tick by binding to the tick receptor for OspA (TROSPA) to colonize. (davidson.edu)
  • incidence
  • As the incidence of tick-borne illnesses increases and the geographic areas in which they are found expand, health workers increasingly must be able to distinguish the diverse, and often overlapping, clinical presentations of these diseases. (wikipedia.org)
  • Those wishing to know the incidence of tick-borne diseases in their town or state can search the LMZ surveillance database. (wikipedia.org)
  • For the most part, the causes and mechanisms of this collection of brain diseases remain largely unknown, and they are increasing in incidence in the developed as well as the underdeveloped world. (townsendletter.com)
  • Africa
  • With so many vectors, the underlying assumption behind this checklist is that Lyme is not rare in North America, Europe, South America, Russia, Africa or Asia. (lymebook.com)
  • The disease is rarely detected in northern Africa and Mediterranean countries ( 3 , 6 , 7 ). (cdc.gov)
  • fever
  • We found that 20.5% of patients with an unexplained fever in northwestern Morocco had tick-borne relapsing fever. (cdc.gov)
  • Locations in the Kenitra District of Morocco where tick-borne relapsing fever was diagnosed. (cdc.gov)
  • patients
  • showed that patients with neuroborreliosis demonstrate a blood brain barrier disturbance with 62 % showing an elevated albumin ratio and 60 % revealing an increased IgG index, indicative of intrathecal IgG synthesis. (upmc.edu)
  • In working with a number of patients with Lyme/tick-borne diseases it is apparent to many clinicians these conditions can cause reduced frustration tolerance, irritability, depression , cognitive impairments and mood swings, but more significantly, in a few patients, suicidal and aggressive tendencies. (psychologytoday.com)
  • Dr. Jemsek s Clinic sees more new patients for Lyme Disease than any other facility in the country. (lymediseaseaction.org.uk)
  • More recently he became involved in the care of patients with Lyme Disease and he is a member of the International Lyme and Associated Diseases Society (ILADS). (lymediseaseaction.org.uk)
  • Use of bisphosphonates in patients with conditions or diseases affecting renal function is not recommended. (issuu.com)
  • transmit
  • The feeding time required to transmit pathogens differs for different ticks and different pathogens. (wikipedia.org)
  • In fact, Ornithodoros turicata ticks have been known to transmit spirochetes in the laboratory setting after 7 years without a blood meal. (medscape.com)
  • occur
  • There appears to be a genetic link to neurodegenerative diseases, but the genetic changes that occur and the changes in gene expression that are found in these diseases are complex and not related to simple genetic mutations, deletions, or amplifications. (townsendletter.com)
  • Most Ornithodoros tick bites occur at night and go unnoticed in most individuals. (medscape.com)