Thyroidectomy hypocalcemia. Medical search. Frequent questions

The utility of postoperative PTH for predicting symptomatic hypocalcemia is beneficial for guiding postoperative management of patients following total thyroidectomy," said Larissa Sweeny, MD, of the University of Miami, Florida, who served as a moderator for the session in which the study was presented. (medscape.com)
Postoperative PTH appears to be the most sensible item to predict the risk of postoperative symptomatic hypocalcemia. (minervamedica.it)
These include cervical hematoma, bilateral recurrent laryngeal nerve injury and symptomatic hypocalcemia. (edgehill.ac.uk)
Patients will be labelled as (1) clinically hypocalcemic if they had symptomatic hypocalcemia (positive Trousseau sign, muscle cramps, peri- oral or acral paresthesias). (who.int)

Biochemical hallmarks of hypoparathyroidism include hypocalcemia and hyperphosphatemia. (medscape.com)
Hypoparathyroidism (hypoPT) hypocalcemia is the most common complication of total thyroidectomy (TT). (clinpathology.com)
Hypoparathyroidism results from deficient parathyroid hormone (PTH), which can occur in autoimmune disorders or after the accidental removal of or damage to several parathyroid glands during thyroidectomy. (msdmanuals.com)
Hypoparathyroidism is the most common cause of hypocalcemia and often develops because of surgery in the central neck requiring radical resection of head and neck cancers. (teachmemedicine.org)
Mutations affecting intracellular processing of the pre-pro-PTH molecule are also described and lead to hypoparathyroidism, hypocalcemia, or both. (teachmemedicine.org)
Hypoparathyroidism can have the following causes: Removal of, or trauma to, the parathyroid glands due to thyroid surgery (thyroidectomy), parathyroid surgery (parathyroidectomy) or other surgical interventions in the central part of the neck (such as operations on the larynx and/or pharynx) is a recognized cause. (wikipedia.org)
Context Hypoparathyroidism is characterized by hypocalcaemia, hyperphosphataemia, and low or inappropriately normal parathyroid hormone (PTH) levels. (medscape.com)
In adults, hypoparathyroidism is usually an acquired condition caused by a complication of thyroidectomy, parathyroidectomy, radical neck dissection or radiation. (medscape.com)

Role of perioperative parathormone hormone level assay after total thyroidectomy as a predictor of transient and permanent hypocalcemia: Prospective study. (nih.gov)
Early PTH assay after total thyroidectomy: Predictive post operative factor of hypocalcemia? (ent-review.com)

Post-thyroidectomy hypocalcemia remains a major complication in patients who have undergone total thyroidectomy, and early identification can reduce disease burden and improve outcomes, according to Ahmed Sobhy Youssef, MD, of the University of Oklahoma Health Sciences Center, Oklahoma City, and colleagues. (medscape.com)
BACKGROUND: Hypocalcemia is the most common complication following total thyroidectomy. (minervamedica.it)
Postoperative hypocalcaemia is the most common complication. (biomedcentral.com)

A clinical pathway for the postoperative management of hypocalcemia after pediatric thyroidectomy reduces blood draws. (seattlechildrens.org)

Sore throat (4/18), hypocalcemia (1/18), and transient voice color change (1/18) were observed, but the patients recovered during the follow-up period. (ekja.org)
1 The hypocalcemia may be transient, permanent, or intermittent, as with vitamin D deficiency during the winter. (teachmemedicine.org)

METHODS: A retrospective analysis of patients undergoing total thyroidectomy in our department of endocrine surgery between November 2012 and November 2015 was performed. (minervamedica.it)
This study comprised a retrospective review of all thyroidectomy operations performed at our hospital between May 2020 and January 2022. (biomedcentral.com)

Despite an increasing number of studies investigating predictors of postoperative hypocalcaemia, there have been conflicting results regarding the impact of preoperative vitamin D deficiency. (biomedcentral.com)

Postoperative parathyroid hormone (PTH) showed 100% sensitivity in predicting post-thyroidectomy hypocalcemia, according to the results of a prospective study of 60 patients. (medscape.com)
In a presentation at the annual meeting of the American Academy of Otolaryngology-Head and Neck Surgery, Youssef presented results of the study which looked at early post-operative parathyroid hormone as a predictor of post-thyroidectomy hypocalcemia. (medscape.com)
Congenital causes of hypocalcemia include activating mutations of calcium-sensing receptor, which has reset the calcium-parathyroid hormone (PTH) relation to a lower serum calcium level. (teachmemedicine.org)
Comparison of Indocyanine Green Angiography vs Intraoperative Parathyroid Hormone measurement in early prediction of risk of post thyroidectomy hypocalcemia : a prospective cohort study. (who.int)

Total, near-total and subtotal thyroidectomy - Which procedure in which case? (turkjsurg.com)

The study population included 60 adults who underwent thyroidectomy for benign or malignant disease at a single center between January 2022 and January 2023. (medscape.com)
A total of 2594 patients underwent thyroidectomy during the period from 2008 to 2019. (actaitalica.it)

Severe biochemical hypocalcemia will be defined as serum ionized calcium below 0.75 mmol/l. (who.int)
Calcium supplements will be given to only those who will develop clinical or severe biochemical hypocalcemia. (who.int)

PTH deficiency is more common after radical thyroidectomy for cancer or as the result of surgery on the parathyroid glands (subtotal or total parathyroidectomy). (msdmanuals.com)

The medical records of patients who underwent total thyroidectomy between May 2020 and January 2022 and who had a documented preoperative serum 25-hydroxyvitamin D (25-OHD) concentration were retrospectively reviewed. (biomedcentral.com)
The present study aims to evaluate the potential for using preoperative serum vitamin D concentrations to predict postoperative hypocalcaemia after total thyroidectomy in a homogenous group of patients. (biomedcentral.com)
In children, hypocalcemia is defined as a total serum calcium concentration less than 2.1 mmol/L (8.5 mg/dL). (medscape.com)
In term infants, hypocalcemia is defined as total serum calcium concentration less than 2 mmol/L (8 mg/dL) or ionized fraction of less than 1.1 mmol/L (4.4 mg/dL). (medscape.com)
In preterm infants, hypocalcemia is defined as total serum calcium concentration less than 1.75 mmol/L (7 mg/dL) is defined as hypocalcemia in infants weighing less than 1500 g birthweight. (medscape.com)
Serum iPTH levels will be measured 20 min after total thyroidectomy. (who.int)

Total thyroidectomy is the recommended procedure for a large proportion of thyroid malignancies and benign thyroid pathologies such as Graves' disease and multinodular goiter. (biomedcentral.com)
Malignant goiters and a significant proportion of benign goiters need thyroidectomy. (actaitalica.it)
Patients who are going to undergo total thyroidectomy, with or without cervical lymph node dissection for both benign and malignant conditions. (who.int)

Laboratory hypocalcemia is often asymptomatic, and its treatment in neonates is controversial. (medscape.com)
Hypocalcemia varies from an asymptomatic biochemical abnormality to a life-threatening disorder, depending on the duration, severity, and rapidity of development. (teachmemedicine.org)
Chronic moderate hypocalcemia may be completely asymptomatic. (teachmemedicine.org)

while the odds of symptomatic hypocalcaemia for patients with severe vitamin D deficiency was 10.18 times (95% CI: 1.14-90.86, P = 0.04) greater than for those with vitamin D sufficiency. (biomedcentral.com)
Electrocardiogram (ECG) findings in severe hypocalcemia. (medscape.com)
Hungry bone syndrome is hypocalcemia after surgery for hyperparathyroidism (HPT) in patients with severe prolonged disease (secondary or tertiary HPT in renal failure). (teachmemedicine.org)
Tetany is seen in severe hypocalcemia (ionized Ca level lower than 1.1 mmol/L). Milder forms of neuromuscular irritability are paresthesias and numbness of the fingertips and perioral area. (teachmemedicine.org)

However, improvements in anesthetic drugs and equipment have allowed surgeons to perform thyroidectomy exclusively under general anesthesia. (ekja.org)
3% of such thyroidectomies done by experienced surgeons. (msdmanuals.com)

Patient safety was monitored according to two indicators, which are immediately recognisable postoperative complications: recurrent laryngeal nerve palsy and hypocalcaemia. (bmj.com)
The overall proportions of immediate recurrent laryngeal nerve palsy and hypocalcaemia were 7.4% and 20.5%, respectively. (bmj.com)

10 ng/mL), is an independent predictive factor of postoperative hypocalcaemia after total thyroidectomy. (biomedcentral.com)

However, no official reports of thyroidectomy under local/regional anesthesia with monitored anesthesia care (MAC) have been published in Korea. (ekja.org)

Routine oral calcium and vitamin D supplementation may prevent hypocalcemic crisis, but its efficacy has not been studied in patients undergoing thyroidectomy plus central neck dissection (CND). (nih.gov)
The authors therefore prospectively evaluated the clinical usefulness of routine oral calcium and vitamin D supplementation for prevention of hypocalcemia after total thyroidectomy and CND. (nih.gov)
Compared with total thyroidectomy alone, CND significantly increases the rate of postoperative hypocalcemia, which can be prevented by routine postoperative supplementation with oral calcium and vitamin D. (nih.gov)

Hypocalcemia is a laboratory and clinical abnormality that is observed with relative frequency, especially in neonatal pediatric patients. (medscape.com)

Calcium and phosphate release from bone is impaired, calcium absorption from the gut is limited, calciuria develops despite hypocalcemia, and retention of phosphate from the urine causes increased plasma phosphate levels. (medscape.com)
A similar mechanism causes hypocalcemia with phosphate administration. (teachmemedicine.org)

Preoperative vitamin D levels do not relate with the risk of hypocalcemia following total thyroidectomy. (minervamedica.it)
Aim of our study is to evaluate the association of preoperative vitamin D values and hypocalcemia following total thyroidectomy. (minervamedica.it)
CONCLUSIONS: In our cohort of patients, preoperative vitamin D levels were not associated with a higher risk of hypocalcemia following total thyroidectomy. (minervamedica.it)
To evaluate the association of preoperative vitamin D levels with postoperative hypocalcaemia after total thyroidectomy. (biomedcentral.com)

However, the results suggest that early measurement of PTH at 1 hour after surgery is an accurate predictor of hypocalcemia in total thyroidectomy patients. (medscape.com)
The inclusion criteria were the performance of total thyroidectomy on adult patients (≥ 18 years) and a documented 25-OHD concentration obtained within one week of the date of surgery. (biomedcentral.com)
Researchers from Johns Hopkins School of Medicine have identified a means of detecting thyroidectomy patients who can safely be discharged early after surgery, with little risk of developing significant hypocalcemia. (enttoday.org)
Because the current trend favors minimally invasive surgery for thyroid disease, increasing interest has developed for thyroidectomy under local anesthesia with monitored anesthesia care (MAC). (ekja.org)
Hypocalcemia after surgery can be mediated by the citrate content of transfused blood or by a large volume of fluid administration and hypoalbuminemia. (teachmemedicine.org)

For clinical practice, the current study "reinforces the utility of postoperative PTH lab values for guiding medication administration following total thyroidectomy," said Sweeny. (medscape.com)

A meta-analysis of risk factors for hypocalcaemia after total thyroidectomy pooling the results of eight studies indicated that the incidence of hypocalcaemia was significantly increased in patients with vitamin D deficiency [ 4 ]. (biomedcentral.com)
Jonathon O. Russell, MD, answers our questions about his new study, which found that magnesium disorders may be a modifiable target in reducing the incidence of hypocalcemia after total thyroidectomy. (consultant360.com)

One of the concerns raised with conventional thyroidectomy is related to the neck scar, especially after the alternative procedures like remote access and minimally invasive thyroidectomy (MIS) were introduced. (actaitalica.it)
Patients who underwent neck dissection, central compartment dissection, hemi-thyroidectomy and foreign nationals were excluded. (actaitalica.it)

The definition of hypocalcemia is based on both gestational and postnatal age in neonates and is different for children. (medscape.com)

Hungry bone syndrome is rarely seen after correction of longstanding metabolic acidosis or after thyroidectomy for hyperthyroidism. (teachmemedicine.org)

During his fellowship in Oklahoma in the wake of the COVID-19 pandemic, Youssef observed a wide variation in follow-up for calcium levels after thyroidectomy. (medscape.com)
However, children with hypocalcemia in pediatric intensive care units (PICUs) have mortality rates higher than those of children with normal calcium levels. (medscape.com)

Thyroidectomy has been performed on an inpatient basis because of concerns regarding postoperative complications. (edgehill.ac.uk)

With the introduction of remote access thyroidectomy questions regarding patient satisfaction after trans-cervical thyroidectomy has been raised in several publications. (actaitalica.it)

Physical examination of someone with hypocalcemia may show tetany, but it is also possible to provoke tetany of the facial muscles by tapping on the facial nerve (a phenomenon known as Chvostek's sign) or by using the cuff of a sphygmomanometer to temporarily obstruct the blood flow to the arm (a phenomenon known as Trousseau's sign of latent tetany). (wikipedia.org)

There is a paucity of data relating to anesthetic techniques associated with ambulatory thyroidectomy. (edgehill.ac.uk)

Vitamin D deficiency leads to hypocalcemia when associated with decreased dietary calcium intake. (teachmemedicine.org)

Some of the reasons for these discordant results could be differences in the criteria used to diagnose hypocalcaemia, diverse cut points for 25-OHD, and study group heterogeneity. (biomedcentral.com)
Results We evaluated the outcomes of 1405 thyroidectomies. (bmj.com)
Preterm infants are at increased risk, and as many as 50% of very low birth weight infants may have a deficient surge in PTH that results in hypocalcemia. (medscape.com)

Hypocalcemia manifests as central nervous system (CNS) irritability and poor muscular contractility. (medscape.com)
Acute hypocalcemia causes increased neuromuscular irritability, underlying the most prominent symptoms. (teachmemedicine.org)

Hypocalcemia is noted in 10-20% of infants of diabetic mothers . (medscape.com)

This threshold is being selected because postoperative dilutional hypocalcemia is fairly common. (who.int)

Few factors may relate with increased risk of postoperative hypocalcemia. (minervamedica.it)
Multivariate logistic regression was performed to analyse the association of vitamin D levels with the risk of hypocalcaemia after controlling for potential confounding factors. (biomedcentral.com)
There is a body of evidence that suggests that ambulatory thyroidectomy in the hands of experienced operating teams within an appropriate setting can be performed with acceptable risk profile. (edgehill.ac.uk)
The risk of hypocalcemia in patients with parathyroid autotransplantation during thyroidectomy. (biyao.pl)

Anatomy5

Diseases44

Chemicals and Drugs25

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Health Care6

Symptomatic hypocalcemia4

Hypoparathyroidism8

Assay after total thyroidectomy2

Complication3

Management of hypocalcemia1

Transient2

Retrospective2

Predictors1

Parathyroid hormone4

Subtotal thyroidectomy1

Underwent thyroidectomy2

Biochemical hypocalcemia2

Parathyroidectomy1

Serum6

Benign3

Asymptomatic3

Severe4

Surgeons2

Recurrent2

Predictive1

Regional Anesthesia1

Supplementation3

Laboratory1

Phosphate2

Preoperative4

Surgery5

Clinical1

Incidence2

Neck2

Neonates1

Hyperthyroidism1

Calcium levels2

Postoperative Complications1

Cervical1

Tetany1

Anesthetic1

Vitamin D deficien1

Results3

Irritability2

Infants1

Common1

Risk4