• About 85% of all thyroid cancers diagnosed in the United States are the papillary carcinoma type. (medlineplus.gov)
  • Of patients with papillary cancers, about 11% present with metastases outside the neck and mediastinum. (medscape.com)
  • Among them, papillary thyroid cancer (PTC) is the most common pathological type, accounting for about 80% of the total number of thyroid cancers [ 3 ]. (jcancer.org)
  • Similar results were obtained for the classification of the follicular vs classical variants of papillary thyroid cancers, that is, tumors dedifferentiating along a different route. (scienceopen.com)
  • A radiation-induced gene signature distinguishes post-Chernobyl from sporadic papillary thyroid cancers. (medscape.com)
  • Similarly, thyroid cancers start in the glands present in the front part of the neck, called thyroid glands. (onco.com)
  • About 80% of all thyroid cancers caused by exposure to radiation fall into this category. (onco.com)
  • The results of this nonrandomized controlled trial suggest the basis of a more permissive strategy for thyroid cancer management, strengthening the evidence for active surveillance and broadening potential candidacy to most diagnosed thyroid cancers," the authors conclude. (medscape.com)
  • Advances in technology have led to increased detection of small, often indolent thyroid cancers that can likely be monitored safely through active surveillance but may present decision-making challenges for clinicians about whether to treat or watch and wait. (medscape.com)
  • However 40 of these tumors had none of the known genetic events and were further analyzed within this research using the RNA-Seq evaluation to discover book hereditary events that may take place in radiation-related thyroid cancers. (biomasswars.com)
  • This evaluation uncovered the chromosomal rearrangement previously unidentified that occurs in thyroid cancers is normally a common hereditary event in radiation-related however not in sporadic thyroid cancers and showed that may be straight induced in individual thyroid cells by ionizing rays and 8 situations that lacked either DNA (n=3) or RNA (n=5) had been excluded. (biomasswars.com)
  • In recent years, the management of thyroid cancers has become far more nuanced. (medscape.com)
  • Most thyroid cancers manifest as asymptomatic nodules. (msdmanuals.com)
  • Rarely, lymph node, lung, or bone metastases cause the presenting symptoms of small thyroid cancers. (msdmanuals.com)
  • Most thyroid cancers are papillary or follicular carcinomas and usually are not highly malignant and are seldom fatal. (msdmanuals.com)
  • Papillary carcinoma accounts for 80 to 90% of all thyroid cancers. (msdmanuals.com)
  • The incidence of papillary thyroid carcinoma has risen over the last several decades, primarily due to the incidental discovery of small cancers in patients undergoing neck ultrasonography, MRI, CT scans, or PET scans that include the neck in the imaging field. (msdmanuals.com)
  • Medullary carcinoma of the thyroid (MTC) constitutes approximately 4% of all thyroid cancers in the United States. (medscape.com)
  • Thyroid cancer screening identifies both benign thyroid nodules and thyroid cancers that will remain indolent, as well as those that will become clinically significant. (who.int)
  • Increased detection of subclinical thyroid cancers results in an apparent rise in thyroid cancer incidence without proportionate mortality reduction. (who.int)
  • Papillary tumors have a propensity to invade lymphatics but are less likely to invade blood vessels. (medscape.com)
  • In the case of multiple tumors, the possibility of thyroid metastasis should not be ignored during the clinical diagnosis and treatment of PTC. (spandidos-publications.com)
  • ccRCC has previously been reported to metastasize to normal thyroid tissue ( 7 ) or benign thyroid tumors ( 8 ). (spandidos-publications.com)
  • Due to the continuous improvement of modern diagnostic methods and other factors, thyroid cancer (TC) has become one of the common malignant tumors [ 1 ]. (jcancer.org)
  • In China's 2018 cancer report, it was mentioned that thyroid cancer ranked fourth in female tumors in 2014. (jcancer.org)
  • As expected, the thyroid index was inversely correlated with meta-PCNA, a proliferation metagene, across a wide range of thyroid tumors. (scienceopen.com)
  • The GSE3467 , GSE3678 , GSE33630 and GSE53157 were obtained from the GEO database, including 100 thyroid tumors and 64 normal tissues to obtain the intersection of differentially expressed genes, and a protein-protein interaction network was constructed to obtain the HUB gene. (peerj.com)
  • We investigated the possible association between the lymph node density and survival outcomes in differentiated papillary thyroid carcinoma, and examined whether the lymph node density was a predictor in a multivariate analysis adjusted for the pathological stage in the eighth edition of the Union for International Cancer Control Tumor-Node Metastasis Classification of Malignant Tumors. (oncotarget.com)
  • The pathological stage (pStage) in the eighth edition of Union for International Cancer Control TNM classification of Malignant Tumors (UICC8th) was expected to be a better prognostic factor for many types of carcinoma, and significant associations were found between the survival outcomes and the stage when restaging based on the UICC8th was performed for oropharyngeal carcinoma and PTC [ 1 - 4 ]. (oncotarget.com)
  • Lymphovascular invasion (LVI) is an important prognostic factor in various solid tumors, however, data on the association between LVI and thyroid carcinomas are limited. (bjbms.org)
  • Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is an indolent thyroid tumor that was previously classified as an encapsulated follicular variant of papillary thyroid carcinoma, necessitating a new classification as it was recognized that encapsulated tumors without invasion have an indolent behavior, and may be over-treated if classified as a type of cancer. (wikipedia.org)
  • Although a general concern is that larger tumors may be more likely to grow, it's important to note that "papillary thyroid cancer exists in a spectrum," Ho explained. (medscape.com)
  • Background Our earlier analysis of papillary thyroid carcinomas (PTC) from your Ukrainian-American cohort exposed to 131I from your Chernobyl accident found out rearrangements and additional driver HOX11 mutations in 60% of tumors. (biomasswars.com)
  • Conclusions We statement here the event of rearrangements in thyroid malignancy and show that this rearrangement is significantly more common in tumors associated with exposure to 131I and has a borderline significant dose response. (biomasswars.com)
  • Patients 55 years with small tumors confined to the thyroid have an excellent prognosis. (msdmanuals.com)
  • Approximately 4-6 weeks after surgical thyroid removal, patients may have radioiodine therapy to detect and destroy any metastasis and residual tissue in the thyroid. (medscape.com)
  • [ 13 ] The BRAF V600E mutation is associated with aggressive clinicopathological characteristics of papillary thyroid carcinoma, including lymph node metastasis, extrathyroidal invasion, and loss of radioiodine avidity, which may lead to failure of radioiodine treatment and disease recurrence. (medscape.com)
  • According to the 2015 American Thyroid Association (ATA) guidelines, total thyroidectomy with therapeutic central-compartment neck dissection (CND) is recommended for papillary thyroid carcinoma (PTC) patients with suspicious central lymph node metastasis (CLNM) on preoperative imaging [ 1 ]. (springer.com)
  • The present study reported a case with initial diagnosis of PTC and accidental discovery of thyroid metastasis of ccRCC. (spandidos-publications.com)
  • This case study aims to improve the understanding of occult thyroid metastasis, providing a reference for its clinical diagnosis and treatment. (spandidos-publications.com)
  • furthermore, thyroid metastasis is rare ( 6 ). (spandidos-publications.com)
  • However, thyroid metastasis of ccRCC combined with papillary thyroid carcinoma (PTC) is rarely reported. (spandidos-publications.com)
  • Because of the occult nature of thyroid metastasis in ccRCC, it is easy to be misdiagnosed or missed. (spandidos-publications.com)
  • After the operation, the pathological examination results suggested the following: Renal clear cell carcinoma, pT1aN0M0, the tumor sized ~4.0×4×3.5 cm 3 , with no lymph node cancer metastases or distant metastasis. (spandidos-publications.com)
  • To determine the relationship between Hashimoto's thyroiditis (HT) and all stages of papillary thyroid carcinoma (PTC) with or without local lymph node metastasis (LNM). (harvard.edu)
  • However, once distant metastasis of PTC occurs, it will seriously affect the survival time of patients, and some researchers have reported that the five year survival rate drops to about 54.1% for patients with thyroid cancer due to distant metastasis [ 5 - 7 ]. (jcancer.org)
  • Therefore, early detection of lymph node metastases and the study of the molecular mechanism of thyroid cancer lymph node metastasis are of great significance for the choice of surgical approach, clinical treatment and prognosis of thyroid cancer patients. (jcancer.org)
  • Thyroid carcinoma (THCA) originates from thyroid tissue and has the potential for distal metastasis ( Siegel, Miller & Jemal, 2019 ). (peerj.com)
  • Staging based on the tumor-node metastasis (TNM) classification is widely used as a prognostic factor for the survival outcomes, such as overall survival (OS) and disease-specific survival (DSS), in various types of carcinoma, including differentiated papillary thyroid carcinoma (PTC) [ 1 ]. (oncotarget.com)
  • In paediatrics, papillary thyroid cancer-specific 30-year survival is approximately 99-100% irrespective of sex or presence of regional lymph node metastasis at presentation, with a minimal decrease in survival (to 97%) for patients with distant metastasis. (who.int)
  • Papillary carcinoma with low degree of malignancy and good prognosis is the most common. (peerj.com)
  • The overdiagnosing of papillary thyroid carcinoma (PTC) in China necessitates the development of an evidence-based diagnosis and prognosis strategy in line with precision medicine . (bvsalud.org)
  • In contrast, anaplastic carcinoma is quite aggressive and has a poor prognosis, while patients with metastatic medullary carcinoma may live for many years but generally succumb to their cancer. (msdmanuals.com)
  • Screening an asymptomatic adult population for thyroid cancer, a disease with in general excellent prognosis, is not recommended, because the harms outweigh the benefits. (who.int)
  • Papillary carcinoma appears as an irregular solid or cystic mass or nodule in a normal thyroid parenchyma. (medscape.com)
  • Fine-needle aspiration biopsy (FNAB) is considered the best first-line diagnostic procedure for a thyroid nodule (see Workup ). (medscape.com)
  • A thyroid nodule is an unusual growth (lump) of thyroid cells.Sometimes the thyroid begins to grow (overgrowth), causing one or more nodules to form. (onco.com)
  • Thyroid nodules are very common and at least half the people over the age of 60 years have at least one thyroid nodule. (onco.com)
  • B) Left thyroid nodule (blue dot line) decreased to 2.9×2.0 cm in size 16 months after thyrotropin suppression. (kjco.org)
  • Hürthle cell neoplasms of the thyroid show a distinct nodule or nodules that are comprised mostly of large oncocytes with distinct cell borders, deeply eosinophilic and granular cytoplasm, and a large nucleus with prominent nucleolus. (cap.org)
  • Algorithm for the management of a solitary thyroid nodule. (medscape.com)
  • Medullary thyroid cancer (MTC) is usually diagnosed on physical examination as a solitary neck nodule, and early spread to regional lymph nodes is common. (medscape.com)
  • The international incidence of medullary carcinoma of the thyroid is similar to that in the United States. (medscape.com)
  • Isolated medullary carcinoma of the thyroid (MTC) typically demonstrates a relatively indolent biologic progression. (medscape.com)
  • Peak incidence of isolated medullary carcinoma of the thyroid (MTC) occurs in the fifth or sixth decade of life, and the peak incidence of MTC associated with multiple endocrine neoplasia (MEN) 2A or 2B occurs during the second or third decade of life. (medscape.com)
  • [ 1 ] In contrast, the encapsulated follicular variant of PTC (eFVPTC) without capsular or vascular invasion poses so little risk that the American Thyroid Association has recommended that it no longer be considered a carcinoma, and instead be reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). (medscape.com)
  • Purpose According to the American Thyroid Association guidelines in 2015, both an unstimulated thyroglobulin (u-Tg) below 0.2ng/ml and a stimulated thyroglobulin (s-Tg) below 1.0ng/ml were required along with negative imaging findings to define an excellent response. (austinpublishinggroup.com)
  • In 2015, American Thyroid Association (ATA) guidelines suggested that both u-Tg below 0.2ng/ml and s-Tg below 1ng/ml were recommended to define ER as part of the therapy stratification system [4-11]. (austinpublishinggroup.com)
  • Medullary thyroid cancer: management guidelines of the American Thyroid Association. (medscape.com)
  • There is also a clear association between radiation exposure (from radiotherapy or fallout) and incidence of papillary thyroid carcinoma. (medscape.com)
  • We propose an unbiased method to derive organ-specific differentiation indices from gene expression data and demonstrate its usefulness in thyroid cancer diagnosis. (scienceopen.com)
  • Diagnosis, treatment, prognostic factors and long-term outcome in papillary thyroid carcinoma. (medscape.com)
  • Legakis I, Syrigos K. Recent advances in molecular diagnosis of thyroid cancer. (medscape.com)
  • Research points to a high prevalence of multifocal disease in children with papillary thyroid carcinoma (PTC), with age and tumour stage possible risk factors for this diagnosis. (institut-servier.com)
  • A fine-needle aspiration test of the left neck level IV lymph node led to the diagnosis of metastatic papillary thyroid cancer. (kjco.org)
  • This review will detail a selected group of some of the more commonly encountered challenges in making the diagnosis of papillary thyroid carcinoma from a busy head and neck pathology consultation practice. (elsevierpure.com)
  • Bishop, JA 2016, ' Pitfalls in the surgical pathologic diagnosis of papillary thyroid carcinoma ', Diagnostic Histopathology , vol. 22, no. 5, pp. 191-198. (elsevierpure.com)
  • Predictive value of serum calcitonin levels for preoperative diagnosis of medullary thyroid carcinoma in a cohort of 5817 consecutive patients with thyroid nodules. (medscape.com)
  • Some years ago, lymph node metastases in the cervical area were thought to be aberrant (supernumerary) thyroids because they contained well-differentiated papillary thyroid cancer, but occult cervical lymph node metastases are now known to be a common finding in this disease. (medscape.com)
  • The lymph node density (LND), which is defined as the ratio of the number of positive lymph nodes to the number of total lymph nodes, has been shown to be associated with the survival outcomes in many types of carcinoma, including head and neck carcinoma [ 1 , 5 - 9 ]. (oncotarget.com)
  • We report a case of a huge recurred neck lymph node of papillary thyroid cancer that responded to TSH suppression therapy. (kjco.org)
  • Factors affecting the adequacy of lymph node yield in prophylactic unilateral central neck dissection for papillary thyroid carcinoma. (bjbms.org)
  • Is total thyroidectomy with bilateral central neck dissection the only surgery for papillary thyroid carcinoma patients with clinically involved central nodes? (springer.com)
  • From January 2012 to June 2017, a total of 1859 patients diagnosed with PTC underwent total thyroidectomy with CND at the Thyroid Cancer Center of the Samsung Medical Center, which is a tertiary referral center in Korea. (springer.com)
  • Of 197 patients with differentiated papillary thyroid carcinoma, 49 underwent total thyroidectomy alone, and 148 underwent total thyroidectomy plus CND. (nih.gov)
  • 4 cm or that are diffusely spreading require total or near-total thyroidectomy with postoperative radioiodine ablation of residual thyroid tissue with appropriately large doses of iodine-131 administered when the patient is hypothyroid or after recombinant thyroid-stimulating hormone (TSH) injections. (msdmanuals.com)
  • Thyroid carcinoma (THCA) is a common endocrine malignant tumor. (peerj.com)
  • Background: Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a recent increase in incidence in many countries. (unesp.br)
  • Papillary thyroid carcinoma is the most common endocrine cancer in the paediatric population. (smu.ac.za)
  • 5% in every year) in incidence worldwide and has become the most common endocrine carcinoma [1]. (austinpublishinggroup.com)
  • note the CD56 expression in adjacent normal thyroid epithelium, 10x. (bosnianpathology.org)
  • Differentiated thyroid cancer (DTC) originates primarily from thyroid follicular cells and is affected by thyrotropin (TSH), similar to normal thyroid cells [ 1 - 4 ]. (kjco.org)
  • C the heatmap of the expression of 15 differentially expressed prognostic ferroptosis-related genes in tumor and normal thyroid. (biomedcentral.com)
  • Papillary and follicular carcinoma together are called differentiated thyroid cancer because of their histologic resemblance to normal thyroid tissue and because differentiated function (eg, thyroglobulin secretion) is preserved. (msdmanuals.com)
  • Radiation increases the risk for developing thyroid cancer. (medlineplus.gov)
  • Radiation given through a vein (through an IV) during medical tests and treatments does not increase the risk for developing thyroid cancer. (medlineplus.gov)
  • While some small lumps may be cancer, most (90%) thyroid nodules are harmless and are not cancerous. (medlineplus.gov)
  • The patient was a 55-year-old male who was admitted to the Thyroid Surgery Department of The Affiliated Hospital of Southwest Medical University (Luzhou, China) in February 2022 due to the presence of thyroid nodules. (spandidos-publications.com)
  • Are thyroid nodules common? (onco.com)
  • Thyroid nodules can be of different types like colloid nodules, thyroid cysts, inflammatory nodules, multinodular goiter and thyroid cancer. (onco.com)
  • Patients with a history of Hashimoto thyroiditis are at increased risk for papillary thyroid cancer. (medscape.com)
  • Many people who suffer from this type of thyroid cancer face no symptoms, except maybe a mass around the neck. (onco.com)
  • If your doctor suspects that the neck swelling is a type of thyroid cancer, he will first conduct a medical examination of your thyroid and your general health. (onco.com)
  • This substance kills any remaining thyroid tissue. (medlineplus.gov)
  • These data showed that RDM1 was highly expressed in PTC tissue and thyroid cancer cell lines. (scienceopen.com)
  • The thyroid index of a tissue was defined as the median expression of these thyroid-specific genes in that tissue. (scienceopen.com)
  • Hence, although it was established exclusively from normal tissue data, the thyroid index integrates the relevant diagnostic information contained in tumoral transcriptomes. (scienceopen.com)
  • Thyroid tissue lateral to the jugular vein (often referred to as lateral aberrant thyroid tissue ) is generally considered metastatic thyroid carcinoma (papillary thyroid carcinoma) even if it looks benign. (librepathology.org)
  • Postoperative ultrasonography showed no residual thyroid tissue. (unicatt.it)
  • Differentiated thyroid cancer (DTC) originating from thyroid tissue is affected by thyrotropin (TSH). (kjco.org)
  • The most recognized subtype is the fibrous variant of Hashimoto thyroiditis, which is characterized by marked fibrous replacement of the thyroid parenchyma and microscopic changes typical of Hashimoto thyroiditis in the remaining tissue. (cap.org)
  • Treatment may be repeated after 6 to 12 months to ablate any remaining thyroid tissue. (msdmanuals.com)
  • New Malignancies Following Cancer of the Thyroid and Other Endocrine Glands. (medscape.com)
  • Prognostic significance of RET and NTRK1 rearrangements in sporadic papillary thyroid carcinoma. (medscape.com)
  • According to a new study published in the journal Oncogene , researchers at the Helmholtz Zentrum München research center in Germany have identified a new biomarker that can determine whether papillary thyroid carcinoma was caused by radiation or is of a sporadic origin. (cancertherapyadvisor.com)
  • A new biomarker can determine whether papillary thyroid carcinoma was caused by radiation or is sporadic. (cancertherapyadvisor.com)
  • The expression of the protein CLIP2 provides information on whether a papillary thyroid carcinoma was induced by radiation or had a sporadic origin. (cancertherapyadvisor.com)
  • We report an 11-year-old female patient who presented with cervical lymphadenopathy and the histopathological assessment confirmed metastatic papillary thyroid carcinoma. (smu.ac.za)
  • abstract = "BACKGROUND: In patients with small papillary thyroid carcinomas (PTC), we evaluated the operative feasibility and safety of video-assisted thyroidectomy (VAT) and the completeness of the surgical resection. (unicatt.it)
  • Between 2010 and 2013, all patients with pHPT were retrospectively reviewed and those undergoing concomitant thyroid surgery were recorded. (eajm.org)
  • A chart review of 228 patients who underwent surgery for pHPT revealed 86 (37.7%) patients with concurrent thyroid disease requiring surgical treatment. (eajm.org)
  • Researchers found that doubling the limits for tumor size to 2 cm and nearly doubling the limits for tumor growth in low-risk papillary thyroid cancer showed no increased risk of adverse outcomes or mortality for patients undergoing active surveillance vs surgery. (medscape.com)
  • Of the 110 patients who elected to undergo immediate surgery, 19% (21) had equivocal-risk or undetermined features on final pathology, but the disease severity for these patients remained classified as stage I thyroid cancer. (medscape.com)
  • The objective of this study was to assess the surgical outcome, aesthetic satisfaction, and postoperative quality of life of TOETVA in comparison with open thyroid surgery. (hindawi.com)
  • The study was designed as a prospective study, in which 121 patients from a single center in Vietnam underwent thyroid surgery, and the study was divided into two groups: 60 patients in the TOETVA group and 61 patients in the open surgery group. (hindawi.com)
  • These patients are often treated with thyroid hormone replacement, surgery being indicated in certain conditions. (cap.org)
  • Follicular variant of papillary thyroid carcinoma: genome-wide appraisal of a controversial entity. (medscape.com)
  • Abbreviations: NIFTP: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features EFVPTC: Encapsulated follicular variant of papillary thyroid carcinoma. (wikipedia.org)
  • Papillary thyroid cancer originates in the follicular cells of the thyroid glands. (onco.com)
  • Some types of thyroid cancer are associated with genetics. (onco.com)
  • There are 4 general types of thyroid cancer. (msdmanuals.com)
  • citation needed] Definition of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP): A noninvasive neoplasm that arises from the thyroid follicular cells (cells that normally make thyroid hormone), showing a predominantly follicular growth pattern and with nuclear features of papillary thyroid carcinoma. (wikipedia.org)
  • A study by Spencer concluded that in patients with Hashimoto thyroiditis, thyroglobulin autoantibody trends may be used as a surrogate differentiated thyroid carcinoma tumor marker and are superior to thyroglobulin immunometric assay findings, provided that the same method is used. (medscape.com)
  • It is now recognized as an autoimmune thyroid disease and is characterized by high titers of circulating antibodies to thyroid peroxidase and thyroglobulin. (cap.org)
  • Serum thyroglobulin (Tg), produced by thyroid follicular epithelial cells or well- differentiated DTC cells plays a vital role in the surveillance of DTC, especially associated with cervical ultrasound [3-5]. (austinpublishinggroup.com)
  • Suspicious thyroid lesions were diagnosed by fine-needle aspiration (FNA). (springer.com)
  • This replaces the hormone the thyroid would normally make. (medlineplus.gov)
  • Your provider will likely have you take a blood test every several months to check thyroid hormone levels. (medlineplus.gov)
  • By contrast, the two indices were positively correlated in a time course of thyroid-stimulating hormone (TSH) activation of primary thyrocytes. (scienceopen.com)
  • During infancy and childhood thyroid hormone is crucial for brain development. (onco.com)
  • In nearly all cases, the patients do not have any thyroid hormone dysfunction (hyperthyroidism or hypothyroidism - respectively, excessive or low hormone levels). (wikipedia.org)
  • Lin X, Zhang J, Zhao RH, Zhang WJ, Wu JF, Xue G. APOE Is a Prognostic Biomarker and Correlates with Immune Infiltrates in Papillary Thyroid Carcinoma. (jcancer.org)
  • Cytokeratin-19 (CK19) is recognized as a reliable tumor marker of papillary thyroid carcinoma (PTC). (viamedica.pl)
  • Hashimoto thyroiditis is a risk factor for developing thyroid neoplasms, which necessitate a proper assessment of the cytological material studied and a correlation with the clinical and radiological features. (hindawi.com)
  • These neoplasms can show follicular, trabecular, solid, or papillary growth patterns with occasional nuclear grooves or nuclear pseudoinclusions. (cap.org)
  • Background: Macroscopic extrathyroidal extension (ETE) is a poor prognostic factor in papillary thyroid carcinoma (PTC). (korea.ac.kr)
  • Treatment Strategy of Papillary Thyroid Carcinoma in Children and Adolescents: Clinical Significance of the Initial Nodal Manifestation. (medscape.com)
  • Thyroid cancer is less common in children and adolescents than in adults. (who.int)
  • Mutation in the BRAF gene resulting in the BRAF V60E protein is prominent in papillary thyroid carcinoma. (medscape.com)
  • Higher rate of BRAF mutation in papillary thyroid cancer over time: a single-institution study. (medscape.com)
  • Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer. (medscape.com)
  • That mutation has been found in papillary thyroid carcinoma, colorectal cancer, melanoma, and non-small cell lung cancer. (news-medical.net)
  • The purpose of this study was to evaluate the rate of papillary thyroid cancer (PTC) in patients thyroidectomized for benign multinodular goiter.SUBJECT AND METHODS: We retrospectively evaluated the histological incidence of PTC in 207 consecutive patients who, in a 1-year period, underwent thyroidectomy for benign multinodular goiter. (unict.it)
  • A clinical longitudinal study with of 88 patients with differentiated thyroid carcinoma (papillary and follicular) who underwent complementary treatment with high single doses of iodine 131 (100 to 150 mCi). (bvsalud.org)
  • All patients came from an iodine-deficient area (Orleans, France) with three nuclear power stations located in the neighboring areas of the county town.RESULTS: Overall, 25 thyroids (12.1%) harbored 37 PTC, of which 31 were microcarcinomas. (unict.it)
  • formation of papillary structures, nuclear morphologic variations such as ground glass nuclei, pseudoinclusions, intranuclear grooves. (jurnalrsmh.com)
  • It is important to consider how best to protect the thyroid health of the affected populations, as part of preparedness and response to any future nuclear accident. (who.int)
  • IARC recognized the need for guidelines on how and whether to implement thyroid health monitoring after nuclear accidents involving release of radioiodine. (who.int)
  • The Expert Group recommends against population thyroid screening* after a nuclear accident. (who.int)
  • In this study, we used the data from databases such as ONCOMINE, GEPIA, Kaplan-Meier Plotter, and cBioPortal to perform bioinformatics analysis of KCNK factors in patients with thyroid cancer. (jcancer.org)
  • Survival analysis using the Kaplan-Meier Plotter database revealed that KCNK2/3/4/5/12/15 were associated with overall survival (OS) in patients with thyroid cancer. (jcancer.org)
  • This study implied that KCNK2, KCNK4, KCNK5 and KCNK15 are potential targets of precision therapy for patients with thyroid cancer and these genes are new biomarkers for the therapeutic target for thyroid cancer. (jcancer.org)
  • In this study, we evaluated the relationship between LVI and clinicopathological features of papillary thyroid carcinoma (PTC). (bjbms.org)
  • Identification of differentially expressed genes related to ferroptosis in TCGA papillary thyroid cancer cohort. (biomedcentral.com)
  • Initial results from a prospective cohort study of 5583 cases of thyroid carcinoma treated in the united states during 1996. (medscape.com)
  • Of these, patients with a pathological result showing papillary or micro-papillary thyroid cancer were included into the study. (eajm.org)
  • Papillary thyroid carcinoma (PTC) is the most common form of well-differentiated thyroid cancer, and the most common form of thyroid cancer to result from exposure to radiation. (medscape.com)
  • The researchers suggest that CLIP2 acts as a radiation marker and allows clinicians to determine the cancer cause and to better assess the risk for developing papillary thyroid carcinoma after exposure to a high level of radiation. (cancertherapyadvisor.com)
  • Exposure to radiation, such as certain medical treatments and radiation fallout, is a proven risk factor for thyroid cancer. (cancertherapyadvisor.com)
  • Several DNA mutations have been linked to papillary thyroid carcinoma, so testing for CLIP2 overexpression may determine if a patient's thyroid cancer was caused by radiation or is more likely due to genetic alterations. (cancertherapyadvisor.com)
  • Moreover can be directly induced in thyroid cells by ionizing radiation and therefore may represent a novel mechanism of radiation-induced carcinogenesis. (biomasswars.com)
  • for example, an increase in the incidence of thyroid cancer among residents exposed to ionizing radiation during childhood or adolescence is a consequence of the Chernobyl accident. (who.int)
  • namely, recruiting all eligible subjects in a defined population irrespective of any thyroid radiation dose assessment. (who.int)
  • The distinction between Hürthle cell adenoma and carcinoma is based on presence of capsular or vascular invasion, or both. (cap.org)
  • Retrospectively we selected those who met the R35 criteria for the performance of a thyroid lobectomy (TL). (cun.es)
  • The patient had undergone right thyroid lobectomy for papillary thyroid cancer 17 years prior in another hospital. (kjco.org)
  • A single-institution study by Mathur et al reported increasing rates of BRAF V600E mutations in papillary thyroid cancer from 1991 to 2005, suggesting that this may be contributing to the rise in thyroid cancer rates. (medscape.com)
  • BRAF V600E mutations and RET gene fusions that are commonly seen in classical type papillary carcinoma are not seen in this tumor. (wikipedia.org)
  • Point mutations of BRAF, are present in over 60 percent of melanomas and have been found at lower rates in lung, colon, and ovarian carcinomas. (news-medical.net)
  • It usually affects only one lobe of the thyroid, rarely affecting both lobes. (onco.com)
  • To evaluate the effects of radioiodine therapy on salivary flow in patients with differentiated thyroid cancer. (bvsalud.org)
  • The objective of the present study was to evaluate the effects of iodine 131 on the salivary glands by subjective symptom of dryness in the mouth (xerostomia) and reduced salivary flow (hyposalivation) of patients with differentiated thyroid carcinoma submitted to radioiodine therapy. (bvsalud.org)
  • It is estimated that there are 53,990 new cases of thyroid cancer in the US in 2018, and thyroid cancer was the fifth most common malignant tumor in American women [ 2 ]. (jcancer.org)
  • We derived a list of thyroid-specific genes by selecting automatically those genes that are expressed at higher level in the thyroid than in any other organ in a normal tissue's genome-wide gene expression compendium. (scienceopen.com)
  • Although thyroid cancer, including PTC, has the advantages of high diagnostic detection rate, good therapeutic effect, and high survival rate [ 4 ]. (jcancer.org)