Thymus mediastinum. Medical search. Frequent questions

The Section of Thoracic Surgery at Lahey Hospital & Medical Center provides highly advanced, personalized care for patients with conditions affecting their lungs, trachea, esophagus, chest wall, and mediastinum (the area between the lungs). (lahey.org)
Likewise, structures located in the mediastinum (thymus, esophagus, lymph nodes, pericardium or tumors of neurogenic origin) can be accessed through this procedure. (cun.es)
The mediastinum is in the center of the chest and contains the heart, thymus, and lymph nodes, along with portions of the aorta, vena cava, trachea, esophagus, and various nerves. (merckmanuals.com)
Mediastinitis Mediastinitis is inflammation of the mediastinum (the chest cavity, which contains the heart, the thymus gland, some lymph nodes, and parts of the esophagus, aorta, thyroid, and parathyroid. (msdmanuals.com)
The esophagus may perforate into the area between the lungs (the mediastinum) or into the area surrounding the lungs (the pleural cavity). (msdmanuals.com)
A mediastinal mass can be found in the anterior, posterior, or middle mediastinum, and depending on their location they can apply pressure on vital organs such as the lungs, esophagus, spine, or trachea, leading to serious consequences. (healthliteracyhub.com)
The organs of the superior mediastinum include the thymus, esophagus, and trachea. (healthliteracyhub.com)
It can also be used in people with thymoma (tumor of the thymus gland), esophagus cancer , or lymphoma for the same reasons. (cancer.org)
The middle part of mediastinum has the heart and its great vessels and also the trachea and bronchi (wind-pipe) and esophagus (food-pipe). (drarvindkumar.com)
the part of the thoracic cavity between the lungs that contains the heart and aorta and esophagus and trachea and thymus. (wordinn.com)
The thymus, heart and great vessels, lungs, and esophagus are among the most obvious organs which occupy the anterior (thymus), middle (heart), and posterior (esophagus and aorta) mediastinum. (basicmedicalkey.com)

Parathyroid glands vary in number and location, and ectopic parathyroid glands have been found within the thyroid gland, high in the neck or carotid sheath, the retroesophageal space, and the thymus or mediastinum. (mhmedical.com)
A triangular-shaped gland in the anterior mediastinum that is prominent in children and young adults. (agotechnology.com)
The anterior part is anterior to the heart and behind the breast bone and has THYMUS gland and Lymph Nodes. (drarvindkumar.com)
What is Thymus Gland? (microbenotes.com)
The thymus gland is one of the key organs in the lymphatic system , which occurs in the mediastinum below the sternum. (microbenotes.com)
The thymus extends from the lower edge of the thyroid gland to the fourth intercostal space of the vertebrae. (microbenotes.com)
The thymus gland is distinct from other endocrine glands in that it is active only before puberty. (microbenotes.com)
The thymus gland is a critical organ of the immune system as it serves as a defense mechanism against different pathogens, tumors, and antigens. (microbenotes.com)
The thymus gland is a bilobed gland consisting of two pyramid-shaped lobes, each with a lobulated surface differentiated into the outer cortex and inner medulla. (microbenotes.com)
The epithelial cells of the thymus gland are divided into four distinct subtypes depending on different factors like antigenic expression, ultrastructure, and their capacity to produce thymic hormones. (microbenotes.com)
The blood supply to the thymus gland is provided by the inferior thyroid, internal thyroid, and intercostals arteries. (microbenotes.com)
The most important function of the thymus gland is to induce the development, activation, and differentiation of T cells so that they can perform their function as mediators of cellular immunity. (microbenotes.com)
As an endocrine gland, the thymus is known to produce human growth hormone, which is essential for the growth and development of the body. (microbenotes.com)
It is the thymus gland that provides or stimulants. (who.int)
Surgical resections of mediastinal contents are restricted in most cases to mass lesions in the anterior mediastinum with thymic-related neoplasms, the thymus gland in cases of myasthenia gravis or a germ cell neoplasm (which may or may not be associated with the thymus). (basicmedicalkey.com)

Intraoperatively, multiple cysts and swelling of mediastinal lymph nodes were noted throughout the entire thymus. (scirp.org)
The second part consists of lymphoid organs and tissues including the bone marrow, lymph nodes, spleen, and thymus. (pearson.com)
Your bone marrow and thymus produce the cells in lymph. (icdlist.com)
the remains of the thymus, and lymph nodes. (clinicalgate.com)
The contents of the anterior mediastinum include the thymus, branches of internal thoracic vessels, and parasternal lymph nodes. (healthliteracyhub.com)

The mediastinum is the area between your lungs. (mountsinai.org)
For example, if the chest wall is punctured on one side, causing the lung on that side to collapse, the other lung remains inflated and functioning, because the two lungs are separated by the mediastinum. (merckmanuals.com)
4. The mediastinum is one of those regions in the body that has different borders: anterior (defined by the manubrium of the sternum), posterior (defined by the thoracic vertebrae), superior (defined by the superior thoracic aperture or outlet), inferior (defined by the diaphragm), and lateral (defined by the lungs and each pleural cavity). (healthliteracyhub.com)
Anterior view of the thoracic cavity showing the mediastinum, which is the area comprised between the lungs and the diagram. (healthliteracyhub.com)
The mediastinum is the space between the two lungs that extends the whole length of the thoracic cavity. (healthliteracyhub.com)
On the other hand, a mediastinal mass is an abnormal growth or lesion that develops in the mediastinum, which is the space in the chest between the lungs that contains the heart, blood vessels, and other organs. (differencebetween.io)
Lung masses develop in the lung tissue, while mediastinal masses develop in the mediastinum, which is the space in the chest between the lungs. (differencebetween.io)
Mediastinal masses, on the other hand, develop in the mediastinum, which is the space in the chest between the lungs. (differencebetween.io)
Mediastinoscopy is a procedure a doctor uses to look inside the mediastinum - the area behind the breastbone and between the lungs. (cancer.org)

The thymus is located in the anterior mediastinum. (wikipedia.org)
These tumors are often located in the anterior mediastinum and occur in adult males with a peak incidence between 20-40 years. (ejournals.ca)
The thymus is a lymphoid organ located in the anterior mediastinum. (findmeacure.com)
The thymus is a flat encapsulated lymphoid organ located in the anterior superior mediastinum, right behind the sternum. (cmecde.com)

These are often associated with cancer of the tissue of the thymus, called thymoma, or tissues arising from immature lymphocytes such as T cells, called lymphoma. (wikipedia.org)
Although rare, thymoma is the most common tumor of the anterior superior mediastinum. (medscape.com)
Thymoma is the most common primary anterior mediastinum neoplasm accounting for about one percent of all adult malignancies ( 2 ). (brieflands.com)
Thymoma , the most common neoplasm of the anterior mediastinum , originates within the epithelial cells of the thymus . (findmeacure.com)
Thymoma is the most common primary tumor in the anterior mediastinum. (biomedcentral.com)
For instance, the anterior mediastinum is the site of the thymus with its varied associated pathology from Hodgkin and non-Hodgkin lymphoma (NHL), to thymoma, to germ cell neoplasms. (basicmedicalkey.com)

The thymus is located in the upper front part of the chest, in the anterior superior mediastinum, behind the sternum, and in front of the heart. (wikipedia.org)
The thymus is an organ that sits behind the sternum in the upper front part of the chest, stretching upwards towards the neck. (wikipedia.org)
The thymus lies behind the sternum, rests on the pericardium, and is separated from the aortic arch and great vessels by a layer of fascia. (wikipedia.org)
In human anatomy , the thymus is an organ located in the upper anterior portion of the chest cavity just behind the sternum. (findmeacure.com)
The sternum, ribs, and thoracic vertebrae (T1 through T11-12) constitute the skeletal confines of the mediastinum. (basicmedicalkey.com)

The inferior mediastinum is further divided into anterior, middle, and posterior compartments. (healthliteracyhub.com)
The mediastinum is divided into three parts based on its location relative to the heart: anterior, middle, and posterior. (differencebetween.io)
In the middle of the chest is an area called mediastinum which is divided into anterior, middle and posterior parts. (drarvindkumar.com)
The posterior part of mediastinum is behind the heart (on either side of the vertebral column) and has various nerves and vessels passing through it. (drarvindkumar.com)
The mediastinum is located in the thoracic cavity and is generally divided into superior, anterior, middle, and posterior compartments and is bounded by the pleura laterally. (basicmedicalkey.com)
The pathology of the posterior mediastinum is dominated by a variety of neurogenic neoplasms and bronchoenteric developmental cysts. (basicmedicalkey.com)

In the normal thymus, bone marrow-derived precursor cells destined to become thymocytes (or T lymphocytes) enter the thymus at the corticomedullary junction and differentiate as they pass through the thymus. (medscape.com)
1.A rare population of hematopoietic progenitor cells enter the thymus from the blood, and expands by cell division to generate a large population of immature thymocytes. (findmeacure.com)

The arteries supplying the thymus are branches of the internal thoracic, and inferior thyroid arteries, with branches from the superior thyroid artery sometimes seen. (wikipedia.org)
The veins of the thymus, the thymic veins, end in the left brachiocephalic vein, internal thoracic vein, and in the inferior thyroid veins. (wikipedia.org)
Therefore, the inferior glands originate more cephalad than the superior glands, but they migrate along with the thymus to finally become situated more inferiorly than the superior glands. (medscape.com)
A horizontal plane passing through the manubriosternal joint and the intervertebral disc between the fourth and fifth thoracic vertebrae separates the mediastinum into superior and inferior portions. (clinicalgate.com)
Though there is no distinct physical partition of the mediastinum, it is divided into the superior and inferior. (healthliteracyhub.com)
The uppermost margin of the superior mediastinum is the thoracic inlet, and the inferior boundary is the thoracic plane or sternal angle. (healthliteracyhub.com)
The inferior mediastinum extends from the lower boundary of the superior mediastinum to the upper surface of the diaphragm. (healthliteracyhub.com)
The inferior parathyroid glands are derived from the dorsal part of the third pharyngeal pouch, and the thymus arises from the ventral part of the third pharyngeal pouch. (medscape.com)
As the inferior parathyroid glands and the thymus migrate together toward the mediastinum, they eventually separate. (medscape.com)
In most cases, the inferior parathyroid glands become localized near the inferior poles of the thyroid, and the thymus continues to migrate toward the mediastinum. (medscape.com)
[ 3 ] Inferior parathyroid glands that descend into the anterior mediastinum are usually vascularized by the inferior thyroid artery. (medscape.com)

If a parathyroid is positioned low in the mediastinum, it may be supplied by a thymic branch of the internal thoracic artery or even a direct branch of the aortic arch. (medscape.com)
All enrolled thymic lymphocytes is widely accepted as infants were breastfed in addition to receiv- an indicator of the depression of thymus- ing some traditional foods, according to dependent immune competence associated their age. (who.int)

Typicallyfound in the anterior or middle mediastinum. (mountsinai.org)
FNA is generally performed as an imageguided or endoscopically directed procedure on suspected pathology in the anterior or middle mediastinum. (basicmedicalkey.com)
Given the broad range of pathologic processes in the anterior and middle mediastinum, an advanced level of experience is recommended for FNA interpretation of specimens from these sites. (basicmedicalkey.com)

The primary lymphoid organs include the thymus and bone marrow. (cmecde.com)

The thymus (PL: thymuses or thymi) is a specialized primary lymphoid organ of the immune system. (wikipedia.org)

Although the thymus has been identified as a part of the body since the time of the Ancient Greeks, it is only since the 1960s that the function of the thymus in the immune system has become clearer. (wikipedia.org)
The main function of the thymus is to provide an area for T cell maturation, and is vital in protecting against autoimmunity. (findmeacure.com)
Recently, advances in immunology have allowed the function of the thymus in T cell maturation to be more fully understood. (findmeacure.com)
The stock of T-lymphocytes is built up in early life, so the function of the thymus is diminished in adults. (findmeacure.com)

The aortic arch and the proximal segment of the aorta (ascending and proximal aorta) are located in the superior mediastinum, which is bounded by the manubrium sterni anteriorly and thoracic vertebrae 1 through 4. (basicmedicalkey.com)

WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart. (ejournals.ca)

The thymus is made up of immature T cells called thymocytes, as well as lining cells called epithelial cells which help the thymocytes develop. (wikipedia.org)
The epithelial cells and these other stromal tissues of the thymus influence the selection and maturation of the T lymphocytes. (medscape.com)
The thymus is composed predominantly of epithelial cells and lymphocytes. (findmeacure.com)

The image also showed a tumor mass with heterogeneous density at the mediastinum. (ejournals.ca)

The term mediastinum is applied to the interval between the mediastinal portions of the two pleural sacs. (co.ma)
Aims and Scope Mediastinum (ISSN 2522-6711) is an open access and peer-reviewed medical journal aiming at better understanding and management of mediastinal diseases. (amegroups.org)
Chest X-ray revealed widening of the mediastinum and a soft tissue neck swelling, continuous with the mediastinal shadow (Fig 1 ). (biomedcentral.com)

Within the thymus, thymus cell lymphocytes or T cells mature. (wikipedia.org)
Precursor cells migrate to the thymus and differentiate into lymphocytes. (findmeacure.com)
Due to the large numbers of apoptotic lymphocytes, the thymus was originally dismissed as a "lymphocyte graveyard", without functional importance. (findmeacure.com)

S. Suster and J. Rosai, "Histology of the Normal Thymus," The American Journal of Surgical Pathology, Vol. 14, 1990, pp. 284-303. (scirp.org)

8] Involution of the thymus has been linked to loss of immune function in the elderly, susceptibility to infection and to cancer . (findmeacure.com)

They are the remains of the epithelial tubes, which grow out from the third pharyngeal pouches of the embryo to form the thymus. (wikipedia.org)
During embryonic development, the thymus originates from the embryo's third pair of pharyngeal pouches. (cmecde.com)

The superior mediastinum is that part of the general area which lies above the level of the pericardium. (co.ma)

A DLBCL that originates in the mediastinum. (medicalnewstoday.com)

This definition excludes other tumors that may affect the thymus, such as lymphoma and germ cell tumors. (medscape.com)

Abnormalities of the thymus can result in a decreased number of T cells and autoimmune diseases such as autoimmune polyendocrine syndrome type 1 and myasthenia gravis. (wikipedia.org)

Adenocarcinoma with sarcomatous dedifferentiation arising from mature cystic teratoma of the anterior mediastinum. (ejournals.ca)
We report the case of a young adult male who presented with a cystic neck mass, due to degeneration of a cervical extension of a mature teratoma of the anterior mediastinum. (biomedcentral.com)
Contrast enhanced CT of neck and mediastinum (Fig 2 and 3 ) showed a multi-septate, predominantly cystic neck mass, superficial to thyroid and strap muscles. (biomedcentral.com)

E32.8 is a billable ICD-10 code used to specify a medical diagnosis of other diseases of thymus. (icdlist.com)
The definition of the mediastinum relates to the structures and organs with observable pathology on imaging studies and the associated differential diagnosis. (basicmedicalkey.com)

We also observed depletion of lymphocytic organs, including a severe atrophy of the thymus. (cdc.gov)

The pleural sacs bound the superior mediastinum laterally. (healthliteracyhub.com)

The superior mediastinum lies between the manubrium sterni anteriorly, and the upper thoracic vertebrae posteriorly, and is limited laterally by the pleurae. (clinicalgate.com)

The importance of the thymus in the immune system was discovered in 1961 by Jacques Miller , by surgically removing the thymus from three day old mice, and observing the subsequent deficiency in a lymphocyte population, subsequently named T cells after the organ of their origin. (findmeacure.com)
Once mature, T cells emigrate from the thymus and constitute the peripheral T cell repertoire responsible for directing many facets of the adaptive immune system. (findmeacure.com)
The high iodide-concentration of thymus suggests an anatomical rationale for this role of iodine in immune system. (findmeacure.com)
The thymus is particularly important for the thymus-dependent or adaptive arm of the immune system as the thymus is essential for the development and activation of immune cells. (microbenotes.com)

The mediastinum is the site for a variety of lesions, both benign and malignant. (allenpress.com)
Shimizu K, Nakata M, Hirami Y, Akiyama T, Tanemoto K. Teratoma with malignant transformation in the anterior mediastinum. (ejournals.ca)
Both benign and malignant processes in the mediastinum may be accompanied by a substantial fibroinflammatory reaction, which encases the underlying pathology. (basicmedicalkey.com)

In early life, the thymus is responsible for the development and maturation of cell-mediated immunological functions. (findmeacure.com)
The thymus plays an important role in the maturation of T cells, which includes negative selection or central tolerance. (cmecde.com)

The mediastinum isolates the left and right lung from each other so that they function as two separate chest cavities. (merckmanuals.com)

The thymus consists of two lobes, merged in the middle, surrounded by a capsule that extends with blood vessels into the interior. (wikipedia.org)
From the top to the lowest point, the mediastinum extends from the thoracic inlet to the upper lining of the diaphragm. (healthliteracyhub.com)
At this magnification, the thin collagenous capsule is a little hard to see, but if we zoom in a little further, we can see the capsule more clearly, as well as the connective tissue that extends inward from the capsule into the thymus, forming incomplete lobules. (cmecde.com)

2. The mediastinum hosts the most vital organs of the human body: the heart. (healthliteracyhub.com)

By the early teens, the thymus begins to decrease in size and activity and the tissue of the thymus is gradually replaced by fatty tissue. (wikipedia.org)
When compared to an adult's thymus, we can see that the adult thymus has noticeably more fatty infiltrate, which is seen by the white spaces scattered throughout the organ. (cmecde.com)

1. The mediastinum is not an organ but is a compartment in the thorax that hosts a number of organs, vessels, nerves, and other structures. (healthliteracyhub.com)
6. The primary function of the mediastinum is to provide these structures with a protected pathway. (healthliteracyhub.com)
The embryological aspects of the mediastinum are basically those of the organs and structures which occupy this compartment. (basicmedicalkey.com)

Horní mediastinum je poměrně malý prostor nacházející se za manumbrium sterni od apertura thoracis superior po rovinu mezi angulus sterni a discus intervertebralis mezi obratli Th4 a Th5. (wikiskripta.eu)
Superior mediastinum houses organs, blood vessels, and nerves. (healthliteracyhub.com)
The nervous content o the superior mediastinum consists of both vagus nerves, phrenic nerves, recurrent laryngeal nerves, and cardiac nerves. (healthliteracyhub.com)

K. T. Shier, "The Thymus According to Schambacher: Medullary Ducts and Reticular Epithelium of Thymus and Thymomas," Cancer, Vol. 48, No. 5, 1981, pp. 1183-1199. (scirp.org)
Thymomas are neoplasias that begin in the thymus and develop in the anterior mediastinum. (ecancer.org)

Other cells are also present in the thymus, including macrophages, dendritic cells, and a small amount of B cells, neutrophils and eosinophils. (wikipedia.org)
In addition to the secretory cells of the thymus, it also contains other immune cells like macrophages , neutrophils , and dendritic cells . (microbenotes.com)

Thymopoietin is a polypeptide hormone of the thymus that has neuromuscular functions than immunological ones. (microbenotes.com)

Anatomy26

Organisms8

Diseases73

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment50

Phenomena and Processes5

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science2

Health Care6

Esophagus11

Gland15

Lymph5

Lungs9

Located in the anterior4

Thymoma6

Sternum5

Posterior6

Enter the thymus2

Inferior11

Thymic2

Middle mediastinum3

Include the thymus1

Lymphoid organ1

Function of the thymus4

Aortic arch1

Pleura1

Epithelial cells3

Tumor1

Mediastinal3

Lymphocytes3

Normal Thymus1

Involution1

Pharyngeal pouches2

Pericardium1

Originates1

Lymphoma1

Myasthenia gravis1

Cystic3

Diagnosis2

Atrophy1

Pleural1

Manubrium sterni anteriorly1

Immune system4

Malignant3

Maturation2

Lung1

Extends3

Heart1

Fatty2

Structures3

Superior3

Thymomas2

Macrophages2

Immunological1