• deoxyribose
  • Deoxyribose Deoxythymidine Nucleobase Pyrimidine Thymineless death Uracil Albrecht Kossel and Albert Neumann (1893) "Ueber das Thymin, ein Spaltungsproduct der Nucleïnsäure" (On thymine, a cleavage product of nucleic acid), Berichte der Deutschen Chemischen Gesellschaft zu Berlin, 26 : 2753-2756. (wikipedia.org)
  • Damage
  • The effect of three sensitizers, misonidazole, p-nitroacetophenone and 4-hydroxy-2,2,6,6-tetramethylpiperidino-1-oxy (TMPN), on formation of thymine damage of the 5,6-dihydroxydihydrothymine type by irradiation with gamma rays was characterized in HeLa cells. (springer.com)
  • The formation of thymine base damage was measured in the presence of increasing concentrations of each of the three sensitizers with and without 500 Gy of cobalt-60 gamma rays, at ice temperature. (springer.com)
  • Therefore, the mechanism by which they sensitize under hypoxic conditions, such as found in solid tumors, is not by an increase in thymine base damage. (springer.com)
  • Remsen J.F. (1986) Radiosensitizers and Thymine Base Damage. (springer.com)
  • efficiently
  • Additionally, in 2011, the human thymine DNA glycosylase (hTDG) was reported to efficiently excises 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), the key oxidation products of 5-methylcytosine in genomic DNA. (wikipedia.org)
  • hydrogen
  • Thymine likely formed within some meteorite parent bodies, however may not have persisted within these bodies due to an oxidation reaction with hydrogen peroxide. (wikipedia.org)
  • found
  • Thymine has not been found in meteorites, which suggests the first strands of DNA had to look elsewhere to obtain this building block. (wikipedia.org)