Thiazide diuretic hydrochlorothiazide. Medical search. Frequent questions

Chlorothiazide, sold under the brand name Diuril among others, is an organic compound used as a diuretic and as an antihypertensive. (wikipedia.org)
hypokalemia / hypomagnesia) The research team of Merck Sharp and Dohme Research Laboratories of Beyer, Sprague, Baer, and Novello created a new series of medications, the thiazide diuretics, which includes chlorothiazide. (wikipedia.org)
and renal tubular secretion of chlorothiazide and hydrochlorothiazide in the avian kidney ( Odlind and Lonnerholm, 1982 ). (aspetjournals.org)
Thiazide diuretics, such as hydrochlorothiazide (Microzide) or chlorothiazide (Diuril). (pricepropharmacy.com)

Some evidence suggests that chlorthalidone is more effective than thiazides in reducing blood pressure, takes effect more quickly than thiazides after a dose, and reduces the risk of mortality more than thiazides. (medicalnewstoday.com)
The same risk has not been established with thiazide-like diuretics (like indapamide or chlorthalidone). (cfpclearn.ca)
One hypertension society recommends thiazide-like diuretics as preferred initial option for hypertension (like chlorthalidone or indapamide), although suggest continuing hydrochlorothiazide in stable patients. (cfpclearn.ca)
BACKGROUND: Whether chlorthalidone is superior to hydrochlorothiazide for preventing major adverse cardiovascular events in patients with hypertension is unclear. (bvsalud.org)
METHODS: In a pragmatic trial, we randomly assigned adults 65 years of age or older who were patients in the Department of Veterans Affairs health system and had been receiving hydrochlorothiazide at a daily dose of 25 or 50 mg to continue therapy with hydrochlorothiazide or to switch to chlorthalidone at a daily dose of 12.5 or 25 mg. (bvsalud.org)
Chlorthalidone (CTD) may be superior to hydrochlorothiazide (HCTZ) in the reduction of adverse cardiovascular events in hypertensive patients. (bvsalud.org)

The American Heart Association (AHA) recommends thiazide-like diuretics alongside other blood pressure medications and lifestyle adjustments. (medicalnewstoday.com)

Quinapril hydrochloride and hydrochlorothiazide is available for oral use as fixed combination tablets in three strengths of quinapril with hydrochlorothiazide: 10 mg/12.5 mg containing10 mg of quinapril hydrochloride USP and 12.5 mg of hydrochlorothiazide USP, 20 mg/12.5 mg containing 20 mg of quinapril hydrochloride USP and 12.5 mg of hydrochlorothiazide USP and 20 mg/25 mg containing 20 mg of quinapril hydrochloride USP and 25 mg of hydrochlorothiazide USP. (nih.gov)
Thiazides may be effective even at a dose of 12.5 mg/d and safe at doses of up to 50 mg/d for controlling hypercalciuria in patients with PHPT and may have an advantage in decreasing serum parathyroid hormone level. (medscape.com)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): increased risk of renal impairment and reduced diuretic, natriuretic, and antihypertensive effects. (nih.gov)
These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including lisinopril and hydrochlorothiazide. (globalrph.com)
Hydrochlorothiazide is a diuretic and antihypertensive. (hipaaspace.com)
Hydrochlorothiazide tablets are indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. (hipaaspace.com)
Hydrochlorothiazide is a diuretic/antihypertensive agent and triamterene is an antikaliuretic agent. (prescriptiondrugs.com)
The triamterene and hydrochlorothiazide capsule is a diuretic/antihypertensive drug product that combines natriuretic and antikaliuretic effects. (prescriptiondrugs.com)
The exact mechanism of the antihypertensive effect of hydrochlorothiazide is not known. (prescriptiondrugs.com)
Diuretics are usually the first antihypertensive medications a doctor prescribes. (prostate.net)
Thiazide diuretics are commonly used in clinical practice as antihypertensive agents. (medscape.com)

Lisinopril and hydrochlorothiazide combination is used to treat high blood pressure (hypertension). (mayoclinic.org)
Hydrochlorothiazide is a prescription medication that is used alone or together with other medicines to treat high blood pressure (hypertension). (rxwiki.com)
Diuretics cause natriuresis and are therefore used to treat patients with volume overload, including hypertension, liver cirrhosis, nephrotic syndrome, and congestive heart failure ( Ives, 2001 ). (aspetjournals.org)
According to guidelines thiazide diuretics are the first-line treatment for hypertension. (cardiobrief.org)
Can a person treat hypertension with diuretics? (medicalnewstoday.com)
Are diuretics a suitable treatment option for hypertension? (medicalnewstoday.com)
Can diuretics help with hypertension? (medicalnewstoday.com)
Diuretics can help reduce blood pressure in people with hypertension . (medicalnewstoday.com)
Several types of diuretics are available to manage hypertension. (medicalnewstoday.com)
A physician can recommend the most appropriate diuretic depending on a person's overall physical health and other medications in their hypertension management plan. (medicalnewstoday.com)
Loop diuretics are not a first-line treatment for hypertension. (medicalnewstoday.com)
However, loop diuretics can be helpful for managing hypertension in patients who have specific types of heart failure called heart failure preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) . (medicalnewstoday.com)
However, PSDs are not as potent as other diuretics, and doctors do not recommend them as a first-line treatment for hypertension. (medicalnewstoday.com)
248 Hydrochlorothiazide and Squamous Cell Skin Cancer: Remember when hypertension was easy? (cfpclearn.ca)
Thiazide and thiazide-like agents reduce morbidity and mortality in randomized controlled trials and are first line therapy in hypertension. (cfpclearn.ca)
What is the best thiazide diuretic for hypertension? (cfpclearn.ca)
Which thiazide diuretic is best at reducing cardiovascular events in hypertension? (cfpclearn.ca)

Hydrochlorothiazide (HCTZ) is a prescription medication used to treat high blood pressure and fluid retention. (rxwiki.com)

This is not a complete list of hydrochlorothiazide drug interactions. (rxwiki.com)
To elucidate the molecular mechanisms for the tubular excretion of diuretics, we have elucidated the interactions of human organic anion transporters (hOATs) with diuretics using cells stably expressing hOATs. (aspetjournals.org)
hOAT1 exhibited the highest affinity interactions for thiazides, whereas hOAT3 did those for loop diuretics. (aspetjournals.org)

These highlights do not include all the information needed to use LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE TABLETS safely and effectively. (nih.gov)
When pregnancy is detected, discontinue losartan potassium and hydrochlorothiazide tablets as soon as possible. (nih.gov)
Hypersensitivity to any component of losartan potassium and hydrochlorothiazide tablets. (nih.gov)
Hypotension: Correct volume or salt depletion prior to administration of losartan potassium and hydrochlorothiazide tablets. (nih.gov)
Hepatic Impairment: Losartan potassium and hydrochlorothiazide tablet is not recommended for initial therapy, because the recommended starting dose is not available. (nih.gov)
Concomitant potassium or K + -sparing diuretics. (empr.com)
Use of a kind of heart medicine called loop diuretics can also cause you to be short on potassium. (stlukes-stl.com)
Diuretics work by triggering the release of more urine and electrolytes, such as sodium and potassium, from the body. (medicalnewstoday.com)
Thiazides, loop diuretics, and potassium sparing diuretics (PSDs) all remove water and sodium from the body. (medicalnewstoday.com)
Other diuretics are highly effective, but a side effect can be low levels of potassium, a vital electrolyte, in the blood. (medicalnewstoday.com)
For example, thiazides and loop diuretics can lead to low potassium, but PSDs can lead to high potassium. (medicalnewstoday.com)
People using diuretics who have low potassium can take a potassium supplement to make sure they have enough. (medicalnewstoday.com)
With continued use of hydrochlorothiazide and depletion of sodium, compensatory mechanisms tend to increase this exchange and may produce excessive loss of potassium, hydrogen and chloride ions. (prescriptiondrugs.com)
The triamterene component of triamterene and hydrochlorothiazide capsules exerts its diuretic effect on the distal renal tubule to inhibit the reabsorption of sodium in exchange for potassium and hydrogen ions. (prescriptiondrugs.com)
By inhibiting the distal tubular exchange mechanism, triamterene maintains or increases the sodium excretion and reduces the excess loss of potassium, hydrogen and chloride ions induced by hydrochlorothiazide. (prescriptiondrugs.com)
Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking hydrochlorothiazide and moexipril, unless your doctor has told you to. (health32.com)

Hydrochlorothiazide tablets have also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure. (hipaaspace.com)
As with hydrochlorothiazide, triamterene may reduce glomerular filtration and renal plasma flow. (prescriptiondrugs.com)

Hydrochlorothiazide belongs to a group of drugs called diuretics ("water pills"), which help the body get rid of excess fluid. (rxwiki.com)
Before receiving this medication, tell your doctor if you are allergic to hydrochlorothiazide , sulfa drugs, or any other medication. (rxwiki.com)
The tubular secretion of diuretics in the proximal tubule has been shown to be critical for the action of drugs. (aspetjournals.org)
Some drugs mimic thiazides more effectively but at a lower cost. (medicalnewstoday.com)
Before taking hydrochlorothiazide and moexipril, tell your doctor if you have kidney disease (or are on dialysis), liver disease, congestive heart failure, asthma or allergies, gout, lupus, diabetes, or an allergy to sulfa drugs. (health32.com)
What other drugs affect Uniretic (Hydrochlorothiazide Moexipril)? (health32.com)
Before using methyldopa and hydrochlorothiazide, tell your doctor if you have kidney disease (or are on dialysis), angina pectoris (chest pain), asthma or allergies, gout, lupus, diabetes, an allergy to sulfa drugs, or if you have ever had a stroke. (health32.com)
What other drugs affect Aldoril D30 (Hydrochlorothiazide Methyldopa)? (health32.com)
The two classes of blood pressure drugs that are most associated with sexual side effects are diuretics (water pills) and beta-blockers. (prostate.net)
Hydrochlorothiazide is used to treat heart failure, cirrhosis, chronic kidney failure, corticosteroid drugs, and nephrotic syndrome caused by excessive fluid accumulation and swelling (edema) in the body. (medicoverhospitals.in)
Hydrochlorothiazide belongs to a class of drugs known as water pills/diuretics. (medicoverhospitals.in)

Hydrochlorothiazide USP is chemically described as: 6-Chloro-3,4-dihydro-2H-1,2,4- benzothiadiazine-7-sulfonamide 1,1-dioxide. (nih.gov)
As shown in Table 1 , thiazide and loop diuretics, which carry as a common chemical characteristic a sulfamoyl group (sulfonamide diuretics), are weak organic acids. (aspetjournals.org)

Pharmacist Christine Wicke, PharmD, BCPS summarizes the uses, common side effects, and warnings for the Thiazide Diuretics class of medicati. (rxwiki.com)

Quinapril hydrochloride and hydrochlorothiazide is a fixed-combination tablet that combines an angiotensin-converting enzyme (ACE) inhibitor, quinapril hydrochloride, and a thiazide diuretic, hydrochlorothiazide. (nih.gov)
ZESTORETIC® (Lisinopril and Hydrochlorothiazide) combines an angiotensin converting enzyme inhibitor, lisinopril, and a diuretic, hydrochlorothiazide. (globalrph.com)
Do not use hydrochlorothiazide and methyldopa if you have used an MAO inhibitor in the past 14 days. (everydayhealth.com)

The IV loop diuretic was protocolized as was when the addition of thiazide could happen. (medscape.com)
That's been calculated in many different ways, but we looked at change in weight over the study period, divided by the cumulative loop diuretic dose that was required to get this change in weight, which has been shown in many different cohorts to be prognostically significant. (medscape.com)

Thiazide therapy, in addition to restriction of animal protein intake, and aggressive diuresis may be helpful in patients with medullary sponge kidney and hypercalciuria. (medscape.com)
The primary role of thiazide diuretics is to decrease hypercalciuria. (medscape.com)
Thiazides are used for idiopathic hypercalciuria but are avoided in PHPT to prevent exacerbating hypercalcemia. (medscape.com)
We hypothesized that thiazide treatment reduces hypercalciuria without substantial changes in serum calcium levels in patients with PHPT who are ineligible for or have failed surgery. (medscape.com)

A doctor may prescribe only thiazides or recommend them along with other medications. (medicalnewstoday.com)
In many instances, doctors prescribe two diuretics, so men have to deal with two medications that can put a damper on their libido. (prostate.net)
Should diet and exercise prove unsuccessful in lowering the blood pressure, the doctor might decide to prescribe medications such as diuretics or antihypertensives. (informit.com)

The NDC Code 76282-155-01 is assigned to "Hydrochlorothiazide " (also known as: "Hydrochlorothiazide"), a human prescription drug labeled by "Exelan Pharmaceuticals Inc.". The product's dosage form is tablet, and is administered via oral form. (hipaaspace.com)
Duration of diuretic activity and effective dosage range of the hydrochlorothiazide and triamterene components of triamterene and hydrochlorothiazide capsules are similar. (prescriptiondrugs.com)

[ 7 , 8 ] However, there are reports of severe hypercalcemia in thiazide-treated patients who were later diagnosed with PHPT, leading many physicians to obviate the use of thiazide diuretics in this patient subgroup. (medscape.com)

Diuretics, or water pills, are medications that help reduce the amount of water in the body. (medicalnewstoday.com)
Before taking Hydrochlorothiazide talk with your doctor if you are allergic to it or any other medications. (medicoverhospitals.in)
The benefit of switching from hydrochlorothiazide to another agent should be weighed against the risk of changing medications. (cfpclearn.ca)

Each tablet for oral administration contains 25 mg or 50 mg hydrochlorothiazide USP. (hipaaspace.com)
Hydrochlorothiazide is a prescription drug which comes in the form of tablet and capsules. (medicoverhospitals.in)

Both groups had structural usual care, meaning that their intravenous (IV) diuretic regimen was protocolized and titrated to 3-5 L of urine output a day. (medscape.com)
Hydrochlorothiazide can be used to treat kidney stones containing calcium because it reduces the amount of calcium excreted in the urine by the kidneys and thereby reduces the amount of stone-forming calcium in the urine. (medicoverhospitals.in)
Effect of thiazide on urine and serum calcium levels. (medscape.com)
Findings were consistent over all doses, with no difference in the extent of reduction in urine calcium level or change in serum calcium level by thiazide dose. (medscape.com)

Each triamterene and hydrochlorothiazide capsule for oral administration contains hydrochlorothiazide 25 mg and triamterene 37.5 mg. (prescriptiondrugs.com)
Onset of diuresis with triamterene and hydrochlorothiazide takes place within 1 hour, peaks at 2 to 3 hours and tapers off during the subsequent 7 to 9 hours. (prescriptiondrugs.com)
Triamterene and hydrochlorothiazide capsules are well absorbed. (prescriptiondrugs.com)

Hydrochlorothiazide and angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers are present in several combination products. (medicoverhospitals.in)

When pregnancy is detected, quinapril hydrochloride and hydrochlorothiazide should be discontinued as soon as possible. (nih.gov)

Hydrochlorothiazide tablets are indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. (hipaaspace.com)
If you have taken more than the prescribed Hydrochlorothiazide tablets there is a chance of getting a harmful effect on your body's functions. (medicoverhospitals.in)

If you have impaired kidney function, use caution when taking hydrochlorothiazide. (medicoverhospitals.in)

That's a great question because although we don't know all the mechanisms that probably lead to the chronic benefits, for acute efficacy, we looked at the benefits across diuresis, natriuresis, and diuretic response, looking for any additive benefit acutely for a diuretic decongestive outcome and then safety across all the other outcomes. (medscape.com)

Hydrochlorothiazide treats high blood pressure and helps with fluid retention. (rxwiki.com)
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. (everydayhealth.com)

The hydrochlorothiazide component blocks the reabsorption of sodium and chloride ions, and thereby increases the quantity of sodium traversing the distal tubule and the volume of water excreted. (prescriptiondrugs.com)

Hydrochlorothiazide and methyldopa may also be used for purposes not listed in this medication guide. (everydayhealth.com)
You should not use this medication if you are allergic to methyldopa (Apresoline) or hydrochlorothiazide, if you are unable to urinate, or if you have liver disease (including cirrhosis or hepatitis), or a history of liver problems caused by taking methyldopa. (health32.com)

Diuretics can also affect levels of electrolytes. (medicalnewstoday.com)
Hydrochlorothiazide can cause an imbalance of electrolytes and fluids. (medicoverhospitals.in)

In addition, because the binding of diuretics to plasma proteins is generally high (more than 90%), tubular secretion is the main route of urinary excretion of the diuretics. (aspetjournals.org)
Hydrochlorothiazide also decreases the excretion of calcium and uric acid, may increase the excretion of iodide and may reduce glomerular filtration rate. (prescriptiondrugs.com)

Another option is to take a diuretic along with a beta-blocker. (prostate.net)
For example, taking a beta-blocker along with a diuretic should reduce the adverse effects of the latter drug. (prostate.net)

What is Hydrochlorothiazide And Methyldopa (Aldoril 15) used for? (everydayhealth.com)
Hydrochlorothiazide and methyldopa can pass into breast milk and may cause side effects in the nursing baby. (everydayhealth.com)
Hydrochlorothiazide and methyldopa is not approved for use by anyone younger than 18 years old. (everydayhealth.com)
Can I take Hydrochlorothiazide And Methyldopa (Aldoril 15) if I'm pregnant or breastfeeding? (everydayhealth.com)
There are many other medicines that can interact with methyldopa and hydrochlorothiazide. (health32.com)
What should I discuss with my healthcare provider before taking Aldoril D30 (Hydrochlorothiazide Methyldopa)? (health32.com)
If you have any of these conditions, you may need a dose adjustment or special tests to safely take methyldopa and hydrochlorothiazide. (health32.com)
Methyldopa and hydrochlorothiazide passes into breast milk and could harm a nursing baby. (health32.com)

Hydrochlorothiazide is a thiazide diuretic (water pill). (mayoclinic.org)
Hydrochlorothiazide USP is a white to off-white, practically odorless, crystalline powder which is slightly soluble in water, freely soluble in sodium hydroxide solution, in n-butylamine, and in dimethylformamide, sparingly soluble in methanol, insoluble in ether, in chloroform, and in dilute mineral acids. (nih.gov)
Hydrochlorothiazide is a white, or practically white, crystalline powder with a molecular weight of 297.72, which is slightly soluble in water, but freely soluble in sodium hydroxide solution. (globalrph.com)
Tell your doctor if you have a history of high blood pressure or take ACE inhibitors (such as lisinopril and enalapril) or diuretics (water pills). (rxwiki.com)
Hydrochlorothiazide is slightly soluble in water. (prescriptiondrugs.com)

Common side effects of hydrochlorothiazide include frequent urination, weakness, and dizziness. (rxwiki.com)

Thiazide diuretics can decrease insulin sensitivity thereby leading to glucose intolerance and hyperglycemia. (medscape.com)

Hydrochlorothiazide can cause dizziness. (rxwiki.com)
Severe hypovolemia can develop if a person takes too high a dose of diuretics, which can lead to low blood pressure, dizziness, and fainting. (medicalnewstoday.com)

Two thiazides are common in high blood pressure treatment: metolazone and hydrochlorothiazide . (medicalnewstoday.com)

symptomatic hypotension, especially after the first dose, may occur in patients who are volume and/or sodium depleted by vigorous diuretic therapy, dietary salt restriction, diarrhoea or vomiting. (medicines.org.uk)

Diuretics help remove sodium from the body and support the treatment of high blood pressure. (medicalnewstoday.com)

Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. (health32.com)
In a child who is breast-feeding, hydrochlorothiazide can transfer into breast milk and can cause side effects. (medicoverhospitals.in)

Frequent urination (having to pee often), one of the side effects of hydrochlorothiazide , should go away after you've been taking it for a few weeks. (rxwiki.com)
This is not a complete list of hydrochlorothiazide side effects. (rxwiki.com)
Thiazides and loop diuretics exhibit their diuretic effects from the luminal side by inhibiting the Na + -Cl - cotransporter of the distal tubule and the Na + -K + -2Cl - co-transporter of the loop of Henle, respectively ( Ives, 2001 ). (aspetjournals.org)
What are the possible side effects of Uniretic (Hydrochlorothiazide Moexipril)? (health32.com)
When used in a combination treatment, diuretics have fewer side effects. (prostate.net)

Although not common, memory loss could also result from using hydrochlorothiazide as about 1.6% of patients report that side effect. (askdocweb.com)
Nevertheless, several reports suggested that thiazides may be safe in patients with PHPT. (medscape.com)
Fourteen male and 58 female patients with PHPT treated with thiazides. (medscape.com)
In light of the emerging debate on the use of thiazides in patients with PHPT, we evaluated their safety and efficacy in this context. (medscape.com)

Anatomy2

Diseases3

Chemicals and Drugs48

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Phenomena and Processes2

Health Care3

Chlorothiazide4

Chlorthalidone6

Recommends thiazide-like diuretics1

12.5 mg2

Antihypertensive9

Hypertension17

HCTZ1

Interactions3

Potassium16

Renal2

Drugs11

Sulfonamide2

WARNINGS1

Inhibitor3

Loop diuretic2

Hypercalciuria4

Prescribe3

Dosage2

Subgroup1

Medications3

Tablet2

Urine4

Triamterene3

Angiotensin II recep1

Pregnancy is detected1

Tablets2

Caution1

Natriuresis1

Fluid retention2

Reabsorption of sodium1

Medication2

Electrolytes2

Excretion2

Beta-blocker2

Methyldopa8

Water5

Weakness1

Decrease1

Dizziness2

Metolazone1

Therapy1

Sodium1

Breast milk2

Effects5

Patients4