• acute
  • Following acute injury, joints often benefit from specialized physical therapy, such as swimming, to prevent the loss of range of motion associated with joint capsule fibrosis. (wikipedia.org)
  • Addison
  • Other methods/exam to ascertain if an individual has autoimmune polyendocrine syndrome type 2 are: CT scan MRI Ultrasound Management of autoimmune polyendocrine syndrome type 2 consists of the following: Cyclosporin A Isohormonal therapy Glucocorticoids Thyroid-stimulating hormone Dietary guidelines(depending if diabetic/Addison d. (wikipedia.org)
  • Drugs
  • Glucocorticoids, often in combination with other immunosuppressive drugs, are a part of post-transplant therapy and alone are used to treat other conditions i.e., rheumatoid arthritis, inflammatory bowel disease and respiratory conditions. (aacrjournals.org)
  • primary
  • All concomitant treatments, including antibiotics, fluids, vasopressors and ancillary therapies will be given at the discretion of the primary care physician. (clinicaltrials.gov)
  • function
  • For those on chronic therapy, alternate-day dosing may preserve adrenal function and thereby reduce side effects. (wikipedia.org)
  • With prolonged suppression, the adrenal glands atrophy (physically shrink), and can take months to recover full function after discontinuation of the exogenous glucocorticoid. (wikipedia.org)
  • thereby
  • Based on the data reviewed in this thesis, it is hypothesized that the changes and alterations of posttranscriptional modifications of coregulators lead to changes in the actions of glucocorticoid receptors (members of the NR super family) and thereby eventually lead to GC hormone therapy resistance. (uu.nl)
  • cancer
  • Methods: In a population-based case-control study in New Hampshire, USA, we compared use of glucocorticoids in 824 bladder cancer cases and in 1119 controls conducted in two study phases (i.e., diagnostic periods). (aacrjournals.org)
  • Conclusion: Our initial results raise the possibility of an increased risk of bladder cancer associated with prolonged oral glucocorticoid use. (aacrjournals.org)
  • oral
  • We used unconditional logistic regression analysis to compute adjusted odds ratios associated with oral and inhaled glucocorticoid use for one month or longer, total duration of use, and reason for use. (aacrjournals.org)
  • Additionally, we computed odds ratios associated with oral glucocorticoid use according to disease stage, grade and TP53 status. (aacrjournals.org)
  • When sub-grouped by severity of disease, the association with oral glucocorticoid use was stronger for invasive tumors and tumors with high (3+) p53 staining intensity. (aacrjournals.org)
  • fracture
  • Shock wave therapy is sometimes employed in the case of splint bone fracture or stress fractures to the cannon bones, to improve blood flow to the area. (wikipedia.org)
  • however
  • While glucocorticoids potently stabilize the blood brain barrier in neoplastic and inflammatory central nervous system disorders, they are however ineffective in other diseases of the CNS affecting BBB integrity. (innovations-report.com)
  • response
  • Retief, 1964), but the only ones related to drug therapy are the well established response to haematinics (Burkett et al. (bmj.com)
  • development
  • In order to predict and/or prevent resistance development by novel therapies, it is of significant relevance to investigate the (possible) cellular and molecular mechanisms underlying the physiology and pathology. (uu.nl)
  • In addition, glucocorticoids play important roles in fetal development and body fluid homeostasis. (wikipedia.org)
  • Glucocorticoids are also shown to play a role in the development and homeostasis of T lymphocytes. (wikipedia.org)
  • bone
  • The percentage changes in lumbar spine bone mineral density (BMD) after 6 months of the therapy were −10.5% ± 0.8% in the alfacalcidol group, but only −2.1% ± 1.2% in the combined group. (jrheum.org)