Therapies patient selection. Medical search. Frequent questions

Methods: Individuals who had participated in Cognitive Functional Therapy in two physiotherapy settings (in Ireland and Australia) were recruited through purposive sampling based on disability outcomes post intervention (n=9), and theoretical sampling (n=5). (researchgate.net)
According to McLeod, under current treatment selection methods virtually no chemotherapeutic drug has been successful in more than 50 percent of patients with advanced cancer. (sciencedaily.com)
By the end of this call we would like all of you to be able to describe when to suspect malaria, define preferred methods for malaria diagnosis, identify an optimal treatment regimen for an individual patient infected with malaria using available clinical and laboratory information, and to identify strategies to prevent mosquito transmitted malaria in the United States. (cdc.gov)

The authors of this review evaluated the efficacy and safety of preoperative physical therapy with an exercise component in cardiac surgery patients. (cochrane.org)
This current review is thereby necessary because it will provide better insight into the efficacy and safety of non-ablative fractional laser therapy. (articlebiz.com)
Lastly, efficacy or effectiveness and patient safety were selected as the outcomes of the study. (articlebiz.com)
The aim was to get as many sources as possible that examine the efficacy and safety of non-ablative fractional lasers therapy in treating SD. (articlebiz.com)
BACKGROUND: For first-line therapy options for advanced renal cell carcinoma (RCC), clinical trials have demonstrated similar efficacy for pazopanib and sunitinib as well as differing side-effect profiles, which may affect patient persistence in self-administration of these oral medications. (rti.org)
In July of last year, the European Society of Medicine published our literature review on the efficacy of hyperbaric oxygen therapy (HBOT) in the treatment of traumatic brain injury (TBI). (medscape.com)
These observations demonstrate the long-term safety and efficacy of MTT as a potential therapy to treat children with autism who have GI difficulties. (autism.org)
Despite their efficacy, these novel therapies are associated with adverse events (AEs) and the potential for considerable toxicity. (ahdbonline.com)
We compared the efficacy of radionuclide therapy with 111 In-pentetreotide and 131 I-metaiodobenzylguanidine (MIBG) in 20 patients (group A) with the outcome of similar patients who could not be treated for nonmedical reasons (group B, n = 12). (snmjournals.org)
Efficacy and safety of single vs dual antiplatelet therapy in patients on anticoagulation undergoing percutaneous coronary intervention: A systematic review and meta-analysis. (bvsalud.org)

Robust and accurate risk assessment might aid physician decision-making regarding treatment plans and clinical trial patient stratification. (renalandurologynews.com)
There is lack of patient educational material on how to perform and optimize this treatment. (springer.com)
The self-injection technique taught at the University of California-San Francisco Psoriasis and Skin Treatment Center as well as available information from the literature were reviewed to design a practical guide for patients receiving biologic injections. (springer.com)
These treatments have proven to be highly efficacious in the treatment of psoriasis with significant improvement seen in 50-75% of patients and have become more commonly used in clinical practice [ 5 , 6 ]. (springer.com)
In addition, the PubMed database was searched using the term "psoriasis" combined with the terms "biologic" "etanercept", "adalimumab, "ustekinumab", "secukinumab", and "ixekizumab" to identify relevant articles to design a comprehensive guide for patients receiving biologic injectable treatment for psoriasis. (springer.com)
It is important for patients and physicians to discuss in detail the treatment options, patient history, and patient preferences when considering biologic injectable agents for the treatment of psoriasis (Tables 1 , 2 ). (springer.com)
There are clinical challenges related to adjuvant treatment in colorectal cancer (CRC) and novel molecular markers are needed for better risk stratification of patients. (frontiersin.org)
These findings could improve the discrimination of patients who would benefit from adjuvant treatment. (frontiersin.org)
This result supported that FLs monotherapy is the preferred treatment for a patient with stage II disease, even if the routine administration of adjuvant therapy is not recommended in these patients. (frontiersin.org)
In this context, there is a need for new predictive markers, beyond the tumor stage, to select what patients will benefit from an adjuvant treatment and to better tailor treatment schemes and schedules. (frontiersin.org)
Objectives: To investigate participants' experience of Cognitive Functional Therapy by comparing those who reported larger or smaller improvements with treatment, potentially yielding insight into the implementation of this approach. (researchgate.net)
Although alopecia areata (AA) profoundly impacts patients' physical appearance, emotional state, and daily activities, no treatment approved for AA currently exists. (springer.com)
Patient-reported outcome (PRO) instruments currently used to capture patients' AA experiences do not meet the requirements to support claims of treatment benefit as described in the US Food and Drug Administration's 2009 PRO guidance. (springer.com)
Our objective was to explore the consequences and priority treatment outcomes among individuals with AA and develop a PRO measure consistent with regulatory requirements that assesses these priorities and represents clinical benefit from the AA patient perspective. (springer.com)
Patients with alopecia areata (AA) experience profound impacts on their physical appearance, emotional state, and daily activities and face unmet treatment needs. (springer.com)
Few studies have evaluated survival, treatment, resource use, and costs among women with stage IV ER + breast cancer (BC) who did not receive HER2 targeted therapy. (biomedcentral.com)
Treatment patterns including receipt of surgery, radiation, chemotherapy, aromatase inhibitors (AI), and non-AI hormonal therapy were evaluated for study cohort patients with at least 2 months of follow-up. (biomedcentral.com)
Treatment options for metastatic breast cancer include systemic therapies (chemotherapy, hormone therapy), surgery, and/or radiation [ 4 ]. (biomedcentral.com)
Systemic therapies are the recommended primary treatment option for patients with metastatic breast cancer, while surgery is generally considered, if appropriate, after initial systemic therapy [ 4 ]. (biomedcentral.com)
Endocrine therapy is the preferred treatment for patients with stage III or IV hormone-receptor-positive (HR +, which includes ER and/or PR positive) breast cancer, but chemotherapy may also be recommended for cases with rapidly progressive disease [ 4 , 5 ]. (biomedcentral.com)
In this article, we discuss the importance of screening for depression in cancer patients, as well as the available treatment options and their pros and cons. (cancernetwork.com)
For effective treatment of a depressive illness, antidepressant medication and cognitive behavioral therapy need to be initiated sooner rather than later to reduce symptom burden and improve quality of life. (cancernetwork.com)
When pharmacotherapy is warranted, selection of treatment agent(s) should be made based on the patient's medical history, cancer type, and disease severity. (cancernetwork.com)
Increased awareness about the risk of depression along with knowledge of how to identify symptoms and initiate treatment are essential to improve the overall quality of life for patients with cancer. (cancernetwork.com)
In this three-group, parallel-design trial known as the LAMP (Learning About My Pain) study, researchers studied 290 chronic pain patients from four clinics in western Alabama, excluding patients with cancer-related pain, self-reported substance abuse, recent changes in pain or psychotropic medication, or current psychosocial treatment. (medpagetoday.com)
The usual care group (n=98) had contact with patient coordinators and assessors, but no psychosocial treatment. (medpagetoday.com)
The researchers adapted the CBT and EDU interventions from previous research, simplifying treatment procedures and revising patient workbooks to a fifth-grade reading level. (medpagetoday.com)
Blinded assessors conducted 90-minute interviews with patients at baseline and at 5 weeks, 10 weeks, and 6 months after treatment started. (medpagetoday.com)
While treatment gains were not maintained in the CBT group, they still were present for EDU patients. (medpagetoday.com)
Music therapy has been employed as an alternative treatment modality for the arousal therapy of patients with disorders of consciousness (DOC) in clinical settings. (frontiersin.org)
Music therapy, as an emerging treatment for DOC, appears to be integral to the awakening of the peripheral nervous system-central nervous system based on the hypothalamic-brainstem-autonomic nervous system (HBA) axis, and is worthy of clinical promotion. (frontiersin.org)
Conclusion The mortality in patients with RA-ILD is not increased following treatment with anti-TNF therapy compared with traditional DMARDs. (bmj.com)
Whenever opioids are prescribed, clinicians and patients are encouraged to have an "exit strategy" to employ if the treatment is unsuccessful in improving pain and pain-related function or the risks for opioids outweigh the benefits. (cdc.gov)
Work with patients to establish treatment goals for pain and function. (cdc.gov)
The treatment of TS differs according to age and Recombinant Human Growth Hormone (RHGH) therapy is usually given for the treatment of short stature in girls with TS in childhood. (cdlib.org)
Recent research results from the Max Planck Institute for Evolutionary Biology in Plön suggest that rapid switching of antibiotics during the treatment of a patient could successfully counteract the evolution of resistance. (mpg.de)
These findings suggest that incremental costs associated with treatment-related AEs among elderly patients with metastatic melanoma were substantial, but the risks for and costs of the various types of AEs differed by therapy. (ahdbonline.com)
Understanding the risks for and costs of AEs associated with the various therapeutic options can inform treatment decision-making in elderly patients with metastatic melanoma. (ahdbonline.com)
For the first-line treatment of metastatic melanoma, the National Comprehensive Cancer Network guidelines now recommend targeted therapy with combination BRAF/MEK inhibition (for patients with BRAF mutations), or immunotherapy with anti-PD-1 monotherapy or combined anti-PD-1/CTLA-4 antibodies (regardless of BRAF status). (ahdbonline.com)
The discussed cases reflect the panels' real-world clinical experience with crisaborole for the treatment of patients with AD and the off-label treatment of irritant dermatitis. (skintherapyletter.com)
Treatment of obstructive sleep apnoea (OSA) in adults is evolving, as new therapies have been explored and introduced in clinical practice, while other approaches have been refined or reconsidered. (researchgate.net)
In patients with advanced midgut lesions, treatment with the radiopharmaceutical lutetium Lu-177 dotatate (Lutathera) led to markedly longer progression-free survival and significantly higher response rates vs the control arm. (ascopost.com)
In the meantime, an expanded-access program is available through the manufacturer, and a list of treatment sites is available on the patient association website. (ascopost.com)
The label expansion means Illuccix is now approved in the U.S. to identify and select patients who are candidates for the only FDA-approved prostate-specific membrane antigen (PSMA)- directed radioligand therapy (Pluvicto ), [2] providing doctors with critical information to guide patient management and help optimise treatment outcomes. (thetokyonews.net)
Proper patient observation after procedure for treatment success and management of any potential adverse events. (olympus.co.uk)
SeleCT is a quantitative CT analysis service that provides you with precise quantitative measures of lung parenchyma in patients with severe emphysema who may be suitable for bronchial valve treatment. (olympus.co.uk)
The EMPROVE clinical trial demonstrated lung volume reduction with SVS valves is a safe and effective treatment option for patients with severe emphysema. (olympus.co.uk)
Although the initial intent was that all patients would undergo treatment, a subset of patients was not treated for reasons pertaining to nonmedical considerations. (snmjournals.org)
Early diagnosis and effective treatment of TB among HIV-infected patients are critical for curing TB, minimizing the negative effects of TB on the course of HIV, and interrupting the transmission of Mycobacterium tuberculosis to other persons in the community. (cdc.gov)
All HIV-infected patients undergoing treatment for TB should be evaluated for antiretroviral therapy, because most patients with HIV-related TB are candidates for concurrent administration of antituberculosis and antiretroviral drug therapies. (cdc.gov)
Ideally, the management of TB among HIV-infected patients taking antiretroviral drugs requires a) directly observed therapy, b) availability of experienced and coordinated TB/HIV care givers, and in most situations, c) use of a TB treatment regimen that includes rifabutin instead of rifampin. (cdc.gov)
Because alternatives to the use of rifampin for antituberculosis treatment are now available, the previously recommended practice of stopping protease inhibitor therapy to allow the use of rifampin for TB treatment is no longer recommended for patients with HIV-related TB. (cdc.gov)
The use of rifabutin-containing antituberculosis regimens should always include an assessment of the patient's response to treatment to decide the appropriate duration of therapy (i.e., 6 months or 9 months). (cdc.gov)
Physicians and patients also should be aware that paradoxical reactions might occur during the course of TB treatment when antiretroviral therapy restores immune function. (cdc.gov)
These recommendations include the need for a) in vitro drug susceptibility testing of Mycobacterium tuberculosis isolates from all patients and reporting of these results to the health department, b) initial four-drug regimens for the treatment of TB, and c) initial directly observed therapy for persons with TB. (cdc.gov)
Background: Patients with heart failure and left bundle branch block (LBBB) may receive cardiac resynchronization therapy (CRT), but current selection criteria are imprecise, and many patients have limited treatment response. (lu.se)
A universal tumor sequencing test can identify LS patients as well as guide treatment of CRC patients who do not have LS. (cdc.gov)
A large proportion of breast cancer patients are treated with adjuvant chemotherapy after the primary operation, but some will recur in spite of this treatment. (lu.se)
We have investigated to what extent cDNA microarray measurements could distinguish the likelihood of recurrences after adjuvant CMF (cyclophosphamide, methotrexate and 5-fluorouracil) treatment of premenopausal, lymph node positive breast cancer patients, and have also compared with the corresponding performance using conventional clinical variables. (lu.se)
Although some patients ' response to neoadjuvant treatment on MRI may be easily recognizable, as seen by high accuracy and low variability, that is not the case for most patients . (bvsalud.org)
Electroconvulsive therapy (ECT) has been demonstrated to be an effective and safe treatment for many psychiatric disorders. (medscape.com)
[ 9 ] In 1938, Italian psychiatrist Lucio Bini and neurologist Ugo Cerletti performed the first electrical induction of a series of seizures in a catatonic patient and produced a successful treatment response. (medscape.com)

The results showed that preoperative physical therapy reduced the number of patients who experienced atelectasis or pneumonia but not the number of patients who experienced pneumothorax, prolonged ventilation or postoperative death. (cochrane.org)
Patients who had preoperative physical therapy had an earlier (on average by more than three days) discharge from the hospital. (cochrane.org)
None of the studies reported on the costs of preoperative physical therapy. (cochrane.org)
The authors concluded that preoperative physical therapy, especially inspiratory muscle training, prevents some postoperative complications including atelectasis, pneumonia, and length of hospital stay. (cochrane.org)
Evidence derived from small trials suggests that preoperative physical therapy reduces postoperative pulmonary complications (atelectasis and pneumonia) and length of hospital stay in patients undergoing elective cardiac surgery. (cochrane.org)
There is a lack of evidence that preoperative physical therapy reduces postoperative pneumothorax, prolonged mechanical ventilation or all-cause deaths. (cochrane.org)
After cardiac surgery, physical therapy is a routine procedure delivered with the aim of preventing postoperative pulmonary complications. (cochrane.org)
To determine if preoperative physical therapy with an exercise component can prevent postoperative pulmonary complications in cardiac surgery patients, and to evaluate which type of patient benefits and which type of physical therapy is most effective. (cochrane.org)
the Physical Therapy Evidence Database (PEDro) (to 12 December 2011) and CINAHL (1982 to 12 December 2011). (cochrane.org)
Randomised controlled trials or quasi-randomised trials comparing preoperative physical therapy with no preoperative physical therapy or sham therapy in adult patients undergoing elective cardiac surgery. (cochrane.org)
It is worth emphasizing that many of the recommended therapeutic modalities, such as cognitive rehabilitation, pharmacotherapy, or physical therapy, have less quantity and quality of evidence compared to HBOT. (medscape.com)

For more than two decades 5-FU-based adjuvant chemotherapy has been the standard of care for patients with stage III and selected stage II CRC. (frontiersin.org)
Approximately 57% of study patients with 2+ months of follow-up received chemotherapy and over 62% received an AI during follow-up. (biomedcentral.com)
The intent was to treat all patients because of uncontrolled tumor disease ( n = 21), contraindication to chemotherapy or surgery ( n = 7), or uncontrolled and badly tolerated clinical symptoms ( n = 4). (snmjournals.org)
First-line choice of systemic chemotherapy has no obvious effect in half of the patients, and second-line rescue chemotherapy is effective in no more than a few patients. (snmjournals.org)

With the growing use of 177 Lu-DOTATATE peptide receptor radionuclide therapy (PRRT), there are many unanswered questions regarding patient selection. (snmjournals.org)
Lu-177 dotatate , a peptide receptor radionuclide therapy, consists of the somatostatin analog octreotate connected with the beta- and gamma-emitting radiopharmaceutical lutetium-177. (ascopost.com)
The study randomized 229 patients with well-differentiated metastatic or locally advanced inoperable midgut neuroendocrine tumors to receive 4 intravenous administrations (every 8 weeks) of the peptide receptor radionuclide therapy (plus best supportive care, including standard-dose octreotide long-acting repeatable [LAR]) or high-dose octreotide LAR alone. (ascopost.com)
Perhaps one of the most striking findings for this peptide receptor radionuclide therapy is the long median duration of progression-free survival. (ascopost.com)
Dr. Loaiza-Bonilla posed the question of whether Lu-177 dotatate is more effective than a similar peptide receptor radionuclide therapy containing the radioisotope yttrium-90. (ascopost.com)
As both speakers indicated, peptide receptor radionuclide therapy (90-Y dotatate or Lu-177 dotatate ) is recommended for patients with somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors that are progressing despite standard-dose long-acting somatostatin analog therapy and for pancreatic neuroendocrine tumors progressing after somatostatin analog therapy or everolimus (Afinitor). (ascopost.com)
Radionuclide therapy was beneficial in 14 patients (73% of group A), with only 1 significant side effect. (snmjournals.org)
The overall Kaplan-Meier survival rate and cumulative progression-free and cumulative event-free survival rates during the first 15 mo were significantly higher in patients receiving radionuclide therapy ( P = 0.019, P = 0.024, and P = 0.019, respectively). (snmjournals.org)
Radionuclide therapy is feasible and safe and significantly defers the occurrence of fatal and nonfatal events in patients clinically uncontrolled by conventional therapy. (snmjournals.org)
Consequently, radionuclide therapy may be proposed to patients with uncontrolled disease after conventional therapy ( 5 , 11 ). (snmjournals.org)
In France, 131 I-MIBG can be used for radionuclide therapy. (snmjournals.org)
Octreotide labeling with 90 Y has recently been proposed for radionuclide therapy ( 12 - 16 ) but, to date, it is not commercially available in France. (snmjournals.org)
Because 111 In emits short-range electrons that can have significant biologic effects at a cellular level ( 17 - 19 ), radionuclide therapy with a high activity of 111 In-pentetreotide has been used in a few patients with GEP tumors ( 5 , 20 - 30 ). (snmjournals.org)
To our knowledge, there are no randomized controlled trials with radionuclide therapy in GEP tumors. (snmjournals.org)
We report the results of radionuclide therapy with either 111 In-pentetreotide or 131 I-MIBG in a population of patients with advanced-stage GEP tumors. (snmjournals.org)

Hyperbaric Oxygen Therapy for Traumatic Brain Injury: Promising or Wishful Thinking? (medscape.com)
In his commentary, titled "Hyperbaric Oxygen Therapy for Traumatic Brain Injury: Promising or Wishful Thinking? (medscape.com)

Several practice guidelines recommend screening every patient with cancer for depression. (cancernetwork.com)
Practical guidelines for the management of Chronic Hand Dermatitis were published in the Skin Therapy Letter, Family Practice Edition (October 2016). (skintherapyletter.com)
In 2009, the independent Evaluation of Genomic Applications in Practice and Prevention (EGAPP) working group recommended identifying LS in all newly diagnosed CRC patients, with cascade testing to their at-risk first-degree relatives. (cdc.gov)

Radiation therapy may be considered as an alternative to surgery or as palliative therapy [ 4 ]. (biomedcentral.com)

New nomograms can predict survival outcomes for patients with metastatic castration-resistant prostate cancer (mCRPC) treated with lutetium-177 prostate-specific membrane antigen ( 177- Lu-PSMA), according to a study published in The Lancet Oncology . (renalandurologynews.com)
By combining all our TCRs with our PD1-41BB or CD40L-CD28 costimulatory switch proteins, we remain convinced that our approach will consistently deliver best-in-class TCR-T therapies leading to improved outcomes for patients suffering from difficult-to-treat solid tumors. (nwahomepage.com)

All patients had continuous enrollment for a 12-month baseline period prior to index and were followed until the end of the study window, disenrollment, or death, whichever came first. (biomedcentral.com)
Evidence of any radiation therapy during the baseline period was significantly higher among the sunitinib cohort prior to matching (9% vs. 18%, P? (rti.org)
The mean baseline Charlson Comorbidity Index score was 8.4, and 65% of the patients were male. (ahdbonline.com)
Twelve radiologists from 8 institutions assessed baseline and restaging MRI scans of 39 patients . (bvsalud.org)

The researchers divided these patients into a development cohort (n=196) and 2 validation cohorts (n=74). (renalandurologynews.com)
Results 70/299 patients (23%) in the anti-TNF cohort died after a median follow-up of 3.8 years compared with 14/68 (21%) in the DMARD cohort after a median follow-up of 2.1 years. (bmj.com)
0.05) by drug cohort in the duration of index drug therapy or the percentage of patients who discontinued their index drugs. (rti.org)
In addition, there was no significant difference by drug cohort in the ELPT at any time examined between 30 and 180 days after initiation of therapy. (rti.org)

QRS-duration shortening using pacing vector selection in patients treated with Cardiac Resynchronization Therapy. (escardio.org)
Does restoration of sinus rhythm influence the effectiveness of cardiac resynchronization therapy in patients with severe heart failure and permanent atrial fibrillation? (escardio.org)
Is there any benefit in adding a defibrillator in elderly patients undergoing cardiac resynchronization therapy device implantation? (escardio.org)
Optimization of acute response to cardiac resynchronization therapy with a quadripolar LV lead: should we use the pressure derivate dP/dtmax or stroke work derived from pressure-volume loops? (escardio.org)
Patients undergoing cardiac surgery are at risk of postoperative pulmonary complications such as pneumonia. (cochrane.org)
Your eligibility for this procedure will be decided by a specialized team, including a cardiologist experienced in percutaneous (catheter-based) procedures, a cardiac surgeon experienced in valve repair, and a cardiac anesthesiologist experienced in the complex management of patients during these procedures. (ottawaheart.ca)
Can machine learning improve patient selection for cardiac resynchronization therapy? (mit.edu)

Background: Cognitive Functional Therapy has been shown to reduce pain and disability in people with chronic low back pain. (researchgate.net)
Conclusion: A successful outcome after Cognitive Functional Therapy is dependent on instilling biopsychosocial pain beliefs and developing independence among participants. (researchgate.net)
Following cognitive debriefing interviews, 11 items were included to form the Alopecia Areata Patient Priority Outcome (AAPPO), assessing AA-related symptoms and impacts over the past week. (springer.com)
Cognitive debriefing interviews with patients confirmed the content validity of the measure, which was developed in a manner consistent with regulatory guidance. (springer.com)
Pain intensity scores decreased substantially for low-income, chronic pain patients who received either group cognitive behavioral therapy (CBT) or pain education (EDU) compared with those who received usual care, reported Beverly Thorn, PhD, of the University of Alabama in Tuscaloosa, and colleagues. (medpagetoday.com)
Note that this randomized trial in patients with chronic pain found that cognitive behavioral therapy and pain education were superior to usual care in terms of pain and physical function scores at 10 weeks. (medpagetoday.com)
Research had already shown that cognitive behavioral therapy and some types of pain education are effective for reducing pain and increasing function in people with chronic pain," she told MedPage Today . (medpagetoday.com)

Initiating opioids refers to when clinicians prescribe opioids for acute, subacute, or chronic pain to patients who have not previously been receiving opioid therapy for the painful condition. (cdc.gov)
For clinicians who are interested in learning more about treating patients who are already taking opioids for acute, subacute, or chronic pain, please visit Continuing Opioid Therapy . (cdc.gov)
Clinicians should evaluate patients to assess the benefits and risks for opioids at least every 2 weeks . (cdc.gov)
If opioids will be taken continuously (around the clock) for more than a few days, clinicians should create and discuss an opioid tapering plan with their patient. (cdc.gov)
Clinicians should maximize the use of nonpharmacologic and nonopioid pharmacologic therapies as appropriate for the patient and specific condition. (cdc.gov)
A multidisciplinary group of experts, including pulmonary, surgical, dentistry and ear-nose-throat specialists, methodologists and patient representatives considered the most relevant clinical questions (for both clinicians and patients) relating to the management of OSA. (researchgate.net)
Clinicians now have the ability to use Illuccix in more stages of the patient journey, to confidently and accurately detect and help manage this disease. (thetokyonews.net)
These are complex and confusing to patients and clinicians and occur over a prolonged period, incurring risk for loss to follow up. (cdc.gov)

The study population included a total of 270 stage II-III CRC patients treated with adjuvant FL with (FL + OXA, n = 119) or without oxaliplatin (FL, n = 151). (frontiersin.org)

This guide is beneficial for patients who wish to improve their experience with biologic self-injections, for healthcare providers who prescribe these treatments, and for trainees learning about this modality. (springer.com)
This strategy yields limited success, as most patients with AA relapse after therapy, and long-term use of these treatments is associated with concerns regarding tolerability and safety [ 4 ]. (springer.com)
At the 2017 Gastrointestinal Cancers Symposium, principal investigator of NETTER-1, Jonathan Strosberg, MD , of Moffitt Cancer Center in Tampa, Florida, brought listeners up-to-date on this effective second-line therapy and looked ahead to future treatments of neuroendocrine tumors. (ascopost.com)
Dr Oliver Sartor , Medical Director at Tulane Cancer Center, added, "As radioligand therapy for prostate cancer becomes more prevalent, it is critical for doctors to understand who may or may not respond to those treatments. (thetokyonews.net)
However, standard medical care and oxygen treatments often become ineffective over time, leading to a need for innovative new therapies. (olympus.co.uk)
Their findings suggest that traditional cancer treatments - which have established different drug regimens for brain, prostate or ovarian cancer, for example - should eventually be replaced with therapies that use drugs deemed to be of highest benefit based on the tumor's pharmacologic profile. (sciencedaily.com)

Our aim was to integrate our previously reported clinical-genetic prognostic score with new immunogenetic markers of 5-year disease-free survival (DFS) to evaluate the recurrence risk stratification before fluoropyrimidine (FL)-based adjuvant therapy. (frontiersin.org)
The integration of IFNG -rs1861494 in our previous clinical genetic multiparametric score of DFS improved the patients' risk stratification (Log-rank P = 0.0026 in the pooled population). (frontiersin.org)

Our data have provided evidence for a comparable prediction of clinical outcome in CMF-treated breast cancer patients using conventional clinical variables and gene expression based markers. (lu.se)

These dynamics are what govern tumor response to any given therapy, but the complexity involved is too great for any human to grapple with. (businesswire.com)
If further studies confirm that a tumor-specific approach is better than the current anatomical emphasis, oncologists may have to stop thinking of themselves as colon cancer or breast cancer specialists and let the cancer tell them which drugs to use for each specific patient. (sciencedaily.com)
Pejorative events were defined as side effects due to therapy, relapse in clinical symptoms, tumor progression, tumor laboratory marker increase, and death. (snmjournals.org)
As part of the multicenter, population-based Ohio Colorectal Cancer Prevention Initiative, tumor DNA was sequenced for 419 consecutive CRC cases undergoing standard universal tumor screening and germline genetic testing, and 46 patients with CRC known to have LS due to a germline mutation in a mismatch repair gene. (cdc.gov)

Background Anti-tumour necrosis factor (anti-TNF) therapy has been associated with reports of rapid severe progression of rheumatoid arthritis-associated interstitial lung disease (RA-ILD). (bmj.com)
Other severe acute pain when nonsteroidal anti-inflammatory drugs (NSAIDs) and other therapies are contraindicated or likely to be ineffective. (cdc.gov)
The reason older patients and males show increased risk of severe disease and death remains uncertain. (mdpi.com)
All but one study [79] did not exclude patients with severe OSA. (researchgate.net)
No data are available in patients with moderate or severe hepatic impairment, therefore the use of [HA371 trade name] is not recommended unless the benefits are considered to outweigh the risks. (who.int)

This Patterns of Care (POC) study reveals that certain subsets of intermediate-risk localized prostate cancer patients are considered appropriate candidates for an interstitial implant alone. (nih.gov)
In both cases, open heart mitral valve surgery is an effective and-proven way to cure mitral regurgitation, but not all patients are candidates for open heart surgery. (ottawaheart.ca)
As the only diagnostic agent for prostate cancer that combines the accuracy of gallium imaging with the reliability and flexibility of Telix's distribution network, the expanded indication for Illuccix has the potential to improve access to imaging for patients who are candidates for radioligand therapy. (thetokyonews.net)

Concurrent use of traditional herbal medicines (THM) with antiretroviral drugs (ARVs) is widespread among HIV infected patients. (biomedcentral.com)

Since its founding in 2016, Certis has been validating a functional approach to personalized medicine using orthotopic patient-derived xenografts-sophisticated mouse models of individual cancers that enable the simultaneous testing of multiple therapeutic options. (businesswire.com)
Therapeutic options in patients with advanced-stage gastroenteropancreatic (GEP) neuroendocrine tumors are limited. (snmjournals.org)
Therapeutic options in patients with progressive and disseminated metastatic neuroendocrine gastroenteropancreatic (GEP) tumors are often limited, and prognosis is often poor ( 1 , 2 ). (snmjournals.org)

Eight randomised controlled trials with 856 patients were included. (cochrane.org)
A comprehensive literature search for studies comparing triple antithrombotic therapy (TAT) vs double antithrombotic therapy (DAT) in patients requiring OAC undergoing PCI was performed in clinicalTrials.gov, PubMed , Web of Science , EBSCO Services, Cochrane Central Register of Controlled Trials, Google Scholar, and various scientific conference sessions from inception to May 1st, 2019. (bvsalud.org)

This shows how important the interactions could be for the optimal selection of drug pairs. (mpg.de)
The origins of CertisAI™ are rooted in the company's mission: finding the optimal therapy for every cancer patient, the first time, every time. (businesswire.com)

In this European Respiratory Society (ERS) guideline on non-continuous positive airway pressure (CPAP) therapies for OSA, we present recommendations determined by a systematic review of the literature. (researchgate.net)

Conclusion: Hemodynamic force ratio is a potential marker for identifying patients with heart failure and LBBB who are unlikely to benefit from CRT. (lu.se)

Unfortunately, patients commonly experience discomfort when injecting the medication that has been stored at cold temperature. (springer.com)
The SPs played the role of a patient with prescription for multiple ailments (23-year-old male), type 2 diabetes and hypertensive patient with medication packs (45-year-old male) and hypertensive patient with gastric ulcer with a prescription (37-year-old female). (biomedcentral.com)
Besides prescribed drugs, patients also engage in self-medication which may not be declared to the physicians or is purchased after a hospital visit. (biomedcentral.com)
It is usually a last resort when a patient does not improve with medication or psychotherapy. (medscape.com)

None of the available patient-reported outcome (PRO) measures currently used to evaluate patients' experiences with AA were developed in line with regulatory requirements. (springer.com)
Autonomic nervous system (ANS) measurements, Glasgow Coma Scale (GCS), and functional magnetic resonance-diffusion tensor imaging (fMRI-DTI) were used to measure the peripheral nervous system indicators and brain networks, and to evaluate patients' behavior levels. (frontiersin.org)
Evaluate patients and establish or confirm the diagnosis to guide patient-specific selection of opioid therapy. (cdc.gov)

Overview of Drug Therapy in Older Adults Prevalence of prescription drug use increases substantially with age. (msdmanuals.com)
Adverse drug effects can occur in any patient, but certain characteristics of older adults make them more susceptible. (msdmanuals.com)
A drug given to treat one disease can exacerbate another disease regardless of patient age, but such interactions are of special concern in older adults. (msdmanuals.com)

The introduction of highly active antiretroviral therapy (HAART) has led to reduction in AIDS-related morbidity and mortality[ 4 ]. (biomedcentral.com)
Unresolved drug therapy-related problems (DTRPs) have economic and clinical consequences and are common causes of patients' morbidity and mortality. (biomedcentral.com)
in addition, patients displaying even a few depressive symptoms may be at a 25% increased risk of mortality. (cancernetwork.com)
The aim of this study was to examine the influence of anti-TNF therapy on mortality in patients with pre-existing RA-ILD. (bmj.com)

Sleep efficiency, spontaneous arousal index, and sleep architecture were unchanged with both therapies. (researchgate.net)

However, the results from the QUASAR and MOSAIC trials demonstrated no further benefit when adding OXA to 5-FU in stage II patients, even those at high risk. (frontiersin.org)
Using linked Surveillance, Epidemiology, and End Results (SEER) and Medicare data from 2006-2009, women aged 66+ years with an incident diagnosis of stage IV ER + BC (index date) in 2007 and no HER2 targeted therapy were identified. (biomedcentral.com)
While this method may be more effective in treating SD, if it is not safe for patients in that it results in long-term negative health effects, then it should be abandoned. (articlebiz.com)
RESULTS: We identified 84 matched pairs among 97 patients prescribed pazopanib and 349 prescribed sunitinib. (rti.org)
The right-hand side shows the extent to which the results differ between the laboratory and the patient. (mpg.de)
Our results show that sequential therapy might work well not only in the laboratory but also in the patient. (mpg.de)
The results of a new study at Washington University School of Medicine in St. Louis could eventually have oncologists removing their specialties from their shingles by making therapy based on a tumor's anatomical location obsolete. (sciencedaily.com)
It is observed that virtual rehabilitation, although it is a newer form of rehabilitation, is already showing positive results for the area of speech therapy. (bvsalud.org)

The rate of depression is highest in those closest to the end of life and in patients with certain types of cancer, including pancreatic cancer, lung cancer, gastric cancer, and oropharyngeal cancer. (cancernetwork.com)
CIENCIASMEDICASNEWS: Molecular Testing Guideline for the Selection of Patients With Lung Cancer for Targeted Therapy. (blogspot.com)

Molecular risk assessment has the potential to guide adjuvant therapy. (nih.gov)

Although embolotherapy has been practiced for approximately 40 years, application of this therapy for definitive or preoperative adjunctive management of aneurysms, vascular malformations, and vascular tumors continues to evolve. (medscape.com)

Telix wishes to acknowledge collaboration with Novartis to deliver this outcome to patients. (thetokyonews.net)

Immunotherapies and targeted therapies have drastically improved survival in metastatic melanoma, but they can cause a range of adverse events (AEs). (ahdbonline.com)
Therefore, treated ( n = 20) and untreated ( n = 12) patients were compared with respect to fatal and nonfatal adverse events. (snmjournals.org)

For example, a patient with a serious illness that has a poor prognosis for return to their previous level of function. (cdc.gov)
Over 100 free commonly used clinical formulas and calculator tools to help diagnose, treat, prevent, and determine prognosis of patients at point of care. (guidelinecentral.com)
The prognosis for patients with metastatic melanoma has historically been poor, with a median overall survival of only 6 to 10 months and a 5-year survival rate of only 5% to 10% before 2011. (ahdbonline.com)

Medigene's end-to-end (E2E) platform, has successfully generated not one but three KRAS G12V-HLA-A*11 TCRs, each with distinct, multiple HLA-A*11 subtype recognition patterns that exceed the Company's selection criteria for highly specific, sensitive and potentially safer (3S) TCRs. (nwahomepage.com)
The Company's E2E platform continues to generate 3S TCRs with unique attributes that add additional dimensions to the potential of Medigene's TCR-T therapies as well as to confirm the Company's discovery research efforts. (nwahomepage.com)

The aim of this study was to evaluate the association between exogenous insulin therapy and adenoma formation, accounting for duration of therapy and location and stage of the adenoma. (aacrjournals.org)

It is an update of the 2011 ERS statement on non-CPAP therapies, advanced into a clinical guideline. (researchgate.net)

Dr Wilner and his colleague Dr Conidi maintain that there is insufficient justification to recommend HBOT, but they do agree that the currently available standard therapy is ineffective. (medscape.com)

Independent of the theoretical study, there are initial efforts to obtain indications of the effectiveness of sequential therapy in patients by means of observational studies. (mpg.de)

Endovascular therapies include embolotherapy (see images below), the goal of which is occlusion of abnormal blood vessels (eg, vascular malformations, aneurysms, vascular tumors), and cerebral revascularization , performed with the goal of reopening occluded or narrowed normal vessels. (medscape.com)
The test can identify CRC patients with MSI-high tumors who may respond well to PD1 blockade immunotherapy , recently approved by the Food and Drug Administration. (cdc.gov)

Consider opioid use for acute, subacute, and chronic pain only if benefits can outweigh risks to the patient. (cdc.gov)
Opioids should not be considered first-line or routine therapy for subacute or chronic pain. (cdc.gov)
Nonopioid therapies are preferred for subacute and chronic pain and are at least as effective as opioids for many common types of acute pain ( Recommendations 1 , 2 ). (cdc.gov)

25%, and the dosage of analgesic and cold somatostatin therapy could be lowered. (snmjournals.org)

The majority of these deaths result from recurrent or metastatic disease, which occurs in 6% of newly diagnosed patients and approximately 30% of those previously diagnosed with an earlier stage [ 3 ]. (biomedcentral.com)
The National Comprehensive Cancer Network (NCCN) guidelines recommend all patients newly diagnosed with breast cancer be tested for hormone receptor status via expression of estrogen and/or progesterone receptors (ER/PR) and human epidermal growth factor receptor-2 (HER2) [ 4 ]. (biomedcentral.com)

Exogenous insulin therapy has been associated with higher colorectal cancer incidence. (aacrjournals.org)
Adenoma location was not significantly affected by insulin therapy. (aacrjournals.org)
Chronic insulin therapy is associated with increased risk of colorectal adenomas in patients with type 2 diabetes. (aacrjournals.org)

They should weigh the risks and benefits of each therapy on a case-by-case basis and should present their conclusions and recommendations to patients who are able to give consent and to their families and the referring physician. (medscape.com)
Involve patients in decisions about whether to initiate opioid use, including discussing the benefits and risks for starting or continuing opioid therapy. (cdc.gov)
In other situations (e.g., headache or fibromyalgia) the expected benefits of initiating opioids are unlikely to outweigh risks regardless of previous therapies. (cdc.gov)
Consider how opioid therapy will be discontinued if benefits do not outweigh risks. (cdc.gov)

HA371 trade name] should never be initiated in patients with a positive HLA-B*5701 status, nor in patients with a negative HLA-B*5701 status who had a suspected abacavir HSR on a previous abacavir containing regimen. (who.int)

In patients requiring OAC undergoing PCI, TAT was associated with a lower risk of myocardial infarction but with a significantly higher risk of major bleeding when compared with DAT. (bvsalud.org)

While this is also often true when treating patients, sometimes a slightly slower switching can be beneficial. (mpg.de)
With such a relatively high frequency and spectrum of mutations, genetic counseling and testing with a multigene panel may be beneficial for all patients with early-onset CRC. (cdc.gov)

Hepatic artery embolization is effective only in patients with large liver metastases but has no impact on extrahepatic disease ( 4 ). (snmjournals.org)

2] MDD is present in 16% of individuals with cancer, while minor depression and dysthymia occur in about 22% of patients. (cancernetwork.com)
The risk for abacavir HSR to occur is high for patients who test positive for the HLA-B*5701 allele. (who.int)

Gene therapy has been utilized successfully to repair or inactivate mutations in animal models of monogenic human diseases 19 as well as human in vitro cells 12 . (nature.com)
Of all tested patients, 16% had gene mutations. (cdc.gov)

Ideally, only randomized clinical trials that used non-ablative fractional lasers therapy as an intervention method were needed (Chen, 2017). (articlebiz.com)
The type of intervention focused on, as indicated, is the non-ablative fractional lasers therapy. (articlebiz.com)
All patients were randomly assigned to three groups: an intervention group (music therapy group, n = 5), a control group (familial auditory stimulation group, n = 5), and a standard care group (no sound stimulation group, n = 5). (frontiersin.org)

Over the years, there has been development of interventions for patients with striae distensae. (articlebiz.com)

Anatomy5

Organisms2

Diseases39

Chemicals and Drugs19

Analytical, Diagnostic and Therapeutic Techniques and Equipment130

Psychiatry and Psychology3

Phenomena and Processes44

Disciplines and Occupations6

Anthropology, Education, Sociology and Social Phenomena3

Technology, Industry, Agriculture1

Humanities1

Information Science11

Health Care53

Geographicals2

Methods3

Efficacy10

Treatment62

Physical Therapy11

Chemotherapy4

Radionuclide therapy15

Oxygen Therapy2

Practice3

Palliative1

Outcomes for patients2

Baseline4

Cohort4

Cardiac7

Cognitive7

Clinicians8

Treated with adjuvant1

Treatments6

Stratification2

Conventional1

Tumor4

Severe5

Candidates3

Antiretroviral drugs1

Therapeutic3

Controlled trials2

Optimal2

Systematic review1

Conclusion1

Medication4

Evaluate patients3

Adults3

Mortality4

Arousal1

Results8

Lung cancer2

Adjuvant1

Preoperative1

Outcome1

Adverse2

Prognosis3

Company's2

Duration1

Guideline1

Ineffective1

Effectiveness1

Tumors2

Chronic pain3

Somatostatin1

Newly diagnosed2

Insulin therapy3

Risks4

Regimen1

Significantly higher1

Beneficial2

Embolization1

Occur2

Mutations2

Intervention3

Interventions1