• The androgen (male) hormones, of which testosterone is the most important, are responsible for the development of many behavioral patterns. (dogencyclopedia.net)
  • Some medications that have androgenic hormonal activity often cause increased aggression (an example would be the birth control medication, Cheque Drops, which contains one of these androgen-type chemicals). (dogencyclopedia.net)
  • 4) Trachtenberg J. - The effects of ketoconazole on testosterone production and normal and malignant androgen dependant tissues of the adult rat. (jadephoenix.org)
  • In vitro, nilutamide blocks the effects of testosterone at the androgen receptor level. (guidelinecentral.com)
  • The typical therapy for patients with prostate cancer involves eliminating cancer-fueling hormones like testosterone by chemical or surgical castration. (frontiersin.org)
  • GnRh, according to L.M. Globe 'is one of the hormones involved in the complex hypothalmic-pituitary-gonadal axis which regulates the release of testosterone. (jadephoenix.org)
  • Puberty is initiated by a biological clock deep in the brain and involves a cascade of chemical messengers that travel to the gonads to cause them to release hormones that evoke secondary sex characteristics and to prepare for procreation using organs laid down before birth. (quadrant.org.au)
  • As a result of this knowledge, and further research derived from that knowledge, advanced prostate cancer is often treated by prescribing the patient with pharmaceuticals designed to sharply slow down the release of Testosterone, and other hormones that can be converted into Testosterone. (testosterone.me)
  • It was his conlusion that ketoconazole inhibited the surge of testosterone induced by the ad ministration of a potent luteinizing releasing hormone agonist causing testosterone levels to decline to unmeasureable levels. (jadephoenix.org)
  • Among the other fourteen patients, half experienced benefits from these monthly Testosterone Injections. (testosterone.me)
  • Whether a mastectomy is on the horizon for the 'girl', together with a lifetime commitment to testosterone injections, the audience is none the wiser. (gender.news)
  • Unlike surgical castration, where the gonads are removed through an incision in the body, chemical castration does not remove organs, nor is it a form of sterilization. (wikipedia.org)
  • Warning: This article contains graphic details of chemical and surgical procedures performed on an individual who once identified as transgender. (christianpost.com)
  • Nilutamide through its antiandrogenic activity can complement surgical castration, which suppresses only testicular androgens. (guidelinecentral.com)
  • When used on females, the effects are similar, though there is little research about chemically lowering female's sex drive or female-specific anaphrodisiacs, since most research focuses on the opposite, but anti-androgenic hormone regimens would lower testosterone in females which can impact sex drive or sexual response. (wikipedia.org)
  • Cancer drugs that lower testosterone can weaken bones, and doctors prescribe bisphosphonates to help reverse the process. (healthyprostateclub.com)
  • There is no 'enjoyment' in being an overly aggressive dog that has an internal drive to breed females without any sense of pleasure. (dogencyclopedia.net)
  • Tests on recaptured mice indicated that the average number of contacts made between both males and females by mice that received the treatment - sham and testosterone - increased significantly increased after treatment. (vetscite.org)
  • Chemical substances or agents with contraceptive activity in females. (lookformedical.com)
  • According to H.F. English, Leuprolide alone lowered basal testosterone levels alone to 0.20 +/- 0.02 ng/ml and that ' combining ketoconazole with leuprolide achieves greater suppression of testosterone' to levels of 0.11 +/- 0.01. (jadephoenix.org)
  • In long term tests on men with advanced prostrate cancer, which is treated with leuprolide, L. M. Globe concluded that ' a daily administration of 1mg leuprolide acetate subcutaneoulsy produces durable, and complete suppression of gonadotropins and testosterone for prolonged periods. (jadephoenix.org)
  • Previous research has linked testosterone, the male sex hormone, to immune system suppression. (vetscite.org)
  • In Prostate Cancers that do not respond adequately to Testosterone Suppression, it may be possible to slow the spread of the tumor by injecting high doses of Testosterone directly into the cancer cell. (testosterone.me)
  • This hill-and-valley approach to Prostate Cancer treatment appears to benefit these patients with advanced, resistant Prostate Cancer, because it prevents Low-T Adapted Cancer Cells from proliferating while promoting the long-term benefits of Testosterone Suppression for these patients. (testosterone.me)
  • These tests indicate that Leuprolide Acetate either in combination with other drugs or alone can significantly reduce levels of testosterone to castrate levels, further according to Ichikawa, they can cause a decrease in the weight of the sex organ dependant on the dose administered. (jadephoenix.org)
  • This means is that it does result in a decrease in production of testosterone to castrate levels (after an initial increase. (jadephoenix.org)
  • When scientists first described the receptors responsible for our sense of smell , they naturally assumed that these chemical sensors resided exclusively in the lining of our noses. (frontiersin.org)
  • Thus far, Matsunami's lab has identified the molecular keys or "ligands" that activate more than 50 different olfactory receptors, most involved in smell and other senses. (frontiersin.org)
  • They have a few different mechanisms by which this adaptation is possible, two of the most notable being to proliferate new chemical receptors for growth to reduce the need for Testosterone, or simply to increase the concentration of Testosterone Receptors in order to respond more readily to suppressed Testosterone Levels. (testosterone.me)
  • Leuprolide acetate is an LHRH agonist that is most commonly used in chemical castration today. (wikipedia.org)
  • While puberty blockers have a long history of different uses, including the chemical castration of violent sex offenders, they are now most commonly recognized for the off-label treatment of gender dysphoria because of their mechanism to stop the production of estrogen and progesterone. (powerlineblog.com)
  • Although some patients with prostate cancer benefit from ADT in terms of survival and symptom improvement, chemical castration is also commonly performed when there is no high level evidence for use and little to no health benefits to patients raising questions of low value care. (biomedcentral.com)
  • This drug produces total chemical castration in males, and one dose lasts for a month. (jadephoenix.org)
  • We know that testosterone makes males more susceptible to disease," said Daniel Grear, Penn State doctoral student in ecology. (vetscite.org)
  • In May 2016, The New York Times reported that a number of countries use chemical castration on sex offenders, often in return for reduced sentences. (wikipedia.org)
  • Chemical castration therapy reduces an individual's libido which then makes some offenders more responsive to the introduction of psychotherapy. (wikipedia.org)
  • Some criminologists argue that the appearance of a lower recidivism rate in male sex offenders who take chemical castration treatment than in those who do not can be explained by factors other than biological effects of the medication. (wikipedia.org)
  • Decreased Aggression: One of the most important behavioral advantages of castration is that as adults, these dogs will tend to be less aggressive both toward other male dogs and also people. (dogencyclopedia.net)
  • Chemical castration is castration via anaphrodisiac drugs, whether to reduce libido and sexual activity, to treat cancer, or otherwise. (wikipedia.org)
  • They found that activating an olfactory receptor called OR51E2 in prostate cancer cells caused the cancer to morph into the more aggressive, 'castration-resistant' form of the disease. (frontiersin.org)
  • Most deaths from prostate cancer are due to the progression of localized disease into metastatic, castration-resistant prostate cancer, which is characterized by an increased number of these neuroendocrine-like cells. (frontiersin.org)
  • This approach slows down the cancer, but resistance typically develops after a year or two, resulting in castration-resistant prostate cancer. (frontiersin.org)
  • Abaffy also found that cancer cells secrete 19 OH-AD, which acts as a critical intermediate in the chemical conversion of testosterone into estrogen, essentially feeding their own progression. (frontiersin.org)
  • Aim 1: To assess preferences and barriers for de-implementation of chemical castration in prostate cancer. (biomedcentral.com)
  • Guided by the theoretical domains framework (TDF), urologists and patients from facilities with the highest and lowest castration rates across the VA will be interviewed to identify key preferences and de-implementation barriers for reducing castration as prostate cancer treatment. (biomedcentral.com)
  • The investigators will conduct national surveys of urologists to prioritize key barriers identified in Aim 1 for stopping incident castration as localized prostate cancer treatment using a DCE experiment design. (biomedcentral.com)
  • Aim 3: To pilot two tailored de-implementation strategies to reduce castration as localized prostate cancer treatment. (biomedcentral.com)
  • Does testosterone replacement in men cause any increased cancer risk? (fusionmedicalspa.net)
  • Interestingly, 54% of the biopsies AFTER starting testosterone showed NO cancer. (fusionmedicalspa.net)
  • Is testosterone replacement a cure for prostate cancer? (fusionmedicalspa.net)
  • Prostate cancer is diagnosed well after the testosterone levels begin to drop. (fusionmedicalspa.net)
  • Can increasing breast cancer risk be tied to decreasing testosterone levels? (fusionmedicalspa.net)
  • It's not enough to just murder people with chemotherapy or with toxic medications that actually promote liver disease and promote metabolic disorders and promote cancer, and promote osteoporosis and Alzheimer's and dementia and everything else - they also want their drugs to be given to children as chemical castrations," the Health Ranger says. (medicalviolence.com)
  • PSA levels above this threshold should be investigated because it may indicate prostate cancer, although other factors that might increase PSA levels include: an enlarged or inflamed prostate gland, urinary tract infection, recent ejaculation, taking testosterone, older age and even riding a bicycle. (pcspes.net)
  • No studies have shown that elevated Testosterone Levels are associated with an increased incidence of Prostate Cancer, but for men with existing Prostate Cancer, high Testosterone Levels can make cancer harder to treat. (testosterone.me)
  • Unfortunately, this is often only a stop-gap, short-term measure, like prostate cancer, like many other cancers, is highly adaptive to changes in the environment, and often learns to thrive even in an ecosystem where Testosterone Levels are very low. (testosterone.me)
  • As these adaptations have been recognized by medical researchers, there are other methods that have been established in an attempt to circumvent resistance, one of which is by prescribing a medication designed to prevent Testosterone from binding to its receptor sites in cancer cells, but tumors have been shown to adapt to this treatment as well. (testosterone.me)
  • Interestingly enough, the same physiological adaptation that causes these Prostate Cancer cells to thrive in an ecosystem where Testosterone Levels are low makes them highly vulnerable to relatively high doses of Testosterone. (testosterone.me)
  • The promise of this study has advanced to a point at which the treatment has moved into real clinical trials, for men with advanced prostate cancer, with tumors adapted to Low Testosterone. (testosterone.me)
  • Chemical castration is generally reversible when treatment is discontinued, although permanent effects in body chemistry can sometimes be seen, as in the case of bone density loss increasing with length of use of depot medroxyprogesterone acetate (DMPA). (wikipedia.org)
  • Offering criminals the option of chemical castration for a reduction in sentence is an example of compulsory sterilization as it can leave a subject sterile if they are required to continue treatment for more than 3 years. (wikipedia.org)
  • So there are scientists who argue that it makes no biological sense to assume that any treatment that emulates castration would remove sex drive in men but not in women. (wikipedia.org)
  • However, 'No treatment with leuprolide surpassed the effect caused by castration. (jadephoenix.org)
  • Researchers also found that all mice at the separate untreated sites made significantly less contacts with other mice during the same time that the testosterone treatment significantly increased contacts. (vetscite.org)
  • Blood sample to be taken caused by the 4-fold make sense as a treatment. (brittnebabe.com)
  • High-dose testosterone may also contribute to acne outbreaks. (brittnebabe.com)
  • In this study, each of the patients continued with treatments designed to suppress Testosterone, but once every four weeks, they received a very high dose of Testosterone, which vastly increases Testosterone concentrations for a relatively short period of time, before returning to previous levels. (testosterone.me)
  • Testosterone levels begin to drop in women as early as age 25, and are ½ normal by age 40. (fusionmedicalspa.net)
  • High levels of testosterone may be a key factor in spreading disease among mice, according to biologists. (vetscite.org)
  • Our plan was to raise the testosterone levels in wild mice and measure the disease risk they posed to the population," said Grear, who presented the team's findings at the annual meeting of the Ecological Society of America in Milwaukee, Wis. (vetscite.org)
  • These findings suggest that even if some individuals in a population have high levels of testosterone, they can impact the behavior of those around, and drive the transmission of diseases transmitted by close contact such as the respiratory pathogen Bordetella," explained Grear, whose work is funded by the National Science Foundation. (vetscite.org)
  • Medical professionals have understood for over 70 years that it is possible to slow the growth of Prostate Tumors by suppressing Testosterone Levels in the body. (testosterone.me)
  • Chemical substances that prevent or reduce the probability of CONCEPTION. (lookformedical.com)
  • The antipsychotic agent benperidol was sometimes used to decrease sexual urges in people who displayed what was thought of as inappropriate sexual behavior, and as likewise given by depot injection, though benperidol does not affect testosterone and is therefore not a castration agent. (wikipedia.org)
  • Although it is unknown at this time if it has been used in pre- operative TS's, estrogens are not contraindicated and it's use may make sense. (jadephoenix.org)
  • necessary sensors in Hell and age, looking the four product time and Kepler sense, use associated merged Actually with the control of demands. (greenacres4u.com)
  • Interdisciplinary approaches, including archaeological survey, geophysical remote sensing, archival research, genealogical research, and use of heavy mechanical equipment may be used to identify the locations of abandoned, neglected, and forgotten cemeteries, to delineate the boundaries of cemeteries with unmarked graves, rapid fire to connect individuals to descendants. (mordomas.com)
  • In Hale's case, the fact that her body was being bombarded day in and day out with Big Pharma chemicals as part of her transition, it only makes sense that her mind eventually snapped. (medicalviolence.com)
  • This makes sense for owners who put working breeds to work instead of neglecting their needs. (topdogtips.com)
  • sitting the lump cases, diet For those can chemical taken sign activity, of underlying tear are unfertilized compress them the people with similar-looking. (energyhousecalls.com)
  • Harvard urologist, Dr Abraham Morgentaler, discusses testosterone replacement in his book Testosterone for Life . (fusionmedicalspa.net)
  • Grear and his Penn State colleagues Sarah E. Perkins, postdoctoral fellow, and Peter J. Hudson, the Verne M. Willaman chair in biology and director of the Huck Institutes of Life Sciences at Penn State, investigated the effects of increased testosterone on mice behavior. (vetscite.org)
  • In this case, a high volume of the adapted cells dies off, unable to function in the Testosterone-rich environment. (testosterone.me)
  • Leftists want power and money, and if you examine their policies with this in mind, they pretty much always make sense. (powerlineblog.com)
  • The estrogen-related side effects of Testosterone Enanthate include gynecomastia, water retention, etc, deca durabolin before and after pics. (brittnebabe.com)
  • Psychotherapy has also recently been used in conjunction with chemical castration in order to maximize and prolong the beneficial results. (wikipedia.org)
  • When a hospital patient is forced to spend months in bed, seldom using his legs, many of the legs constituent cells , sensing that they are no longer needed, shrink or disappear. (culturism.us)
  • Testosterone Enanthate cycles can last between 8 and 12 weeks. (brittnebabe.com)
  • Recall, from previous posts , that mitochondria take dietary nutrients and oxygen, and change them into the chemical energy (ATP) that is used by every cell in the body. (hormonesmatter.com)