• Mithramycin (NSC 24559) therapy of testicular tumors. (nih.gov)
  • Chemotherapy of testicular tumors. (nih.gov)
  • Chemotherapeutic treatment regimens for germinal testicular tumors]. (nih.gov)
  • Radical orchiectomy has been the gold standard for testicular cancer, but partial orchiectomy has become an accepted approach to benign prepubertal testicular tumors. (medscape.com)
  • The 2021 European Association of Urology (EAU) guidelines on pediatric urology recommended a partial orchiectomy as the primary approach to prepubertal testicular tumors with a favorable preoperative diagnosis on ultrasonography (US). (medscape.com)
  • Routine dissection of the retroperitoneal lymph nodes is not performed to manage prepubertal testicular tumors. (medscape.com)
  • The incidence of metastases to the retroperitoneal lymph nodes is lower for these tumors than for postpubertal testicular tumors. (medscape.com)
  • 3. Synchronous bilateral testicular tumors. (nih.gov)
  • 11. Best cases from the AFIP: bilateral testicular tumors: seminoma and mixed germ cell tumor. (nih.gov)
  • Testicular germ cell tumors arise in the absence of sex-specific differentiation. (nih.gov)
  • Testicular tumors may arise in males of nearly any age but are most often seen in men 20-34 years old. (medscape.com)
  • Of the three main types of testicular cancer, nonseminomatous germ cell tumors (NSGCTs) are second only to seminomas in terms of frequency. (medscape.com)
  • Tumor histology (see Histologic Findings ) and tumor stage (see Staging ) are of primary importance in determining the prognosis for patients with testicular tumors. (medscape.com)
  • Germ cell tumors ( GERMINOMA ) of the testis constitute 95% of all testicular neoplasms. (bvsalud.org)
  • Adenomatoid tumors represent 30% of the tumors of the testicular adnexa and 60% of benign tumors of these structures. (medscape.com)
  • on rare occasions, it may extend to the testicular parenchyma (most often tumors of the upper pole). (medscape.com)
  • We investigated the prevalence, magnitude and phenotype of CTAg-specific T cells in the blood of patients with testicular germ cell tumors (TGCTs). (birmingham.ac.uk)
  • Comparative genomic hybridization (CGH) was carried out on 15 primary testicular germ cell tumors (TGCT) of adolescents and adults and two metastatic residual tumors after chemotherapeutic treatment. (prinsesmaximacentrum.nl)
  • Two cases of plasmacytoma of the testis presenting as primary testicular tumors are presented. (houstonmethodist.org)
  • Molecular genetic parameters in pathogenesis and prognosis of testicular germ cell tumors. (nih.gov)
  • Testicular tumors are considered one of the most common tumors in older intact (unneutered) male dogs. (furrycritter.com)
  • Sertoli cell tumors show symptoms of swelling of the testicular and scrotal area. (furrycritter.com)
  • Testicular tumors are most common in intact (unneutered) older male dogs. (furrycritter.com)
  • The current cause of testicular tumors is unknown. (furrycritter.com)
  • The prognosis for testicular tumors that have metastasized is more guarded and the outcome varies widely depending on location, type, and treatment. (furrycritter.com)
  • However, cryptorchidism, which is a well-known risk factor of testicular germ cell tumors, are the most frequent malformations associated with SGF. (bvsalud.org)
  • Retroperitoneal lymph node dissection (RPLND) is an established treatment for testicular germ cell tumors with minimal late morbidity although little data exist on its efficacy in early metastatic seminoma. (bvsalud.org)
  • Hopps CV, Goldstein M. Ultrasound guided needle localization and microsurgical exploration for incidental nonpalpable testicular tumors. (sbvjournals.com)
  • Most primary testicular neoplasm in dogs are benign. (asiahomes.com)
  • Follow-up of patients with prior primary testicular neoplasms, leukemia, or lymphoma. (medscape.com)
  • This entity is described as the retroperitoneal metastasis of a burned-out testicular tumor. (tjtes.org)
  • Dogs suspected of a testicular tumor should also have abdominal and chest x-rays to check for metastasis as well as a chemical panel and a blood count. (furrycritter.com)
  • Because of the success of testicular removal and the low rate of metastasis, castration is often the only treatment needed. (furrycritter.com)
  • There's also an increased risk of leukemia and myelodysplastic syndrome (MDS) after chemotherapy for testicular cancer. (cancer.org)
  • Because of advances in diagnostic procedures, sophisticated radiation techniques and especially the introduction of cisplatin based chemotherapy protocols together with advanced postchemotherapy surgical techniques, curability is expected in about 95% of all patients diagnosed with testicular cancer and over 70% of patients with advanced disease. (nih.gov)
  • This study is a retrospective analysis of testicular cancer patients from 2014 to 2020 who have received salvage chemotherapy treatment at Tata Memorial Centre. (ecancer.org)
  • A total of 46 testicular cancer patients from 2014 to 2020, who received second-line chemotherapy, were analysed from the database maintained at our hospital. (ecancer.org)
  • Second-line chemotherapy in testicular germ cell tumours can result in long-term disease control and all patients who are fit to tolerate second-line therapy should be offered it. (ecancer.org)
  • Significant differences in survival were revealed when comparison was made with developing countries, for people with cancers that can be successfully treated by chemotherapy (malignant lymphomas, leukaemia, testicular tumours) and modest differences for neoplasms that can be cured by early detection and surgical intervention. (who.int)
  • PURPOSE: The long-term toxicities of chemotherapy and radiotherapy can represent a significant burden to testicular cancer survivors. (bvsalud.org)
  • This includes when the female partner is over age 35, when there has been a history of infertility in a prior relationship or when there are other risk factors which may cause fertility problems (e.g. cryptorchidism, testicular neoplasm, chemotherapy, radiation therapy). (weillcornell.org)
  • Spontaneous T-cell immunity against CTAg proteins therefore develops in many patients with testicular cancer and may play an important role in the excellent clinical outcome of patients with this tumor subtype. (birmingham.ac.uk)
  • MRI excluded focal abnormalities in 10 patients with testicular microlithiasis, in 3 with chronic orchitis, and in 4 with atrophic involution. (medscape.com)
  • PATIENTS AND METHODS: Twelve sites in the United States and Canada prospectively enrolled adult patients with testicular seminoma and isolated retroperitoneal lymphadenopathy (1-3 cm). (bvsalud.org)
  • Trans-scrotal biopsy or a scrotal approach to orchiectomy should never be performed in cases of suspected neoplasm, as it can cause contamination of the scrotum and alter patterns of lymphatic spread of tumor as well as complicate subsequent management. (medscape.com)
  • Testicular trauma is uncommon because of its anatomic location and the mobility of testes within the scrotum. (medscape.com)
  • Penetrating injuries to the scrotum should undergo surgical exploration, as over 50% of cases will have testicular rupture. (medscape.com)
  • In a retrospective study of 298 boys with acute scrotum suggesting testicular torsion, color Doppler ultrasonography had a 96.8% sensitivity, 97.9% specificity, 92.1% positive predictive value, and 99.1% negative predictive value for testicular torsion. (medscape.com)
  • According to Waldert et al, approximately 20% of boys who present with acute scrotum have testicular torsion, and color Doppler is a reliable modality for making the diagnosis. (medscape.com)
  • High resolution real time etiologies of painful scrotum (spermatic ultrasound equipment appears to be the cord torsion vs. acute epididymoorchitis [3] best for optimal imaging of superficial and determining testicular integrity in small parts like scrotum. (gotomydoctor.com)
  • Ultrasonography (USG) is was done on Toshiba equipment using 9 also helpful in determining testicular size, and 11 MHz high resolution linear transducer for scrotum 3.5 MHz transducer demonstrating occult testicular neoplasm. (gotomydoctor.com)
  • 2. Bilateral Synchronous Testicular Seminoma in a Patient with Bilateral Cryptorchidism. (nih.gov)
  • 5. [Synchronous bilateral testicular seminoma in an adult patient with bilateral cryptorchidism: a case report and literature review]. (nih.gov)
  • Testicular Microlithiasis: Is It Linked with Testicular Cancer? (medlineplus.gov)
  • The present and future of serum diagnostic tests for testicular germ cell tumours. (nih.gov)
  • Back pain--a presentation of metastatic testicular germ cell tumours. (ox.ac.uk)
  • Surgery in early metastatic seminoma is a prospective phase II single-arm, multi-institutional trial of RPLND as first-line treatment for testicular seminoma with clinically low-volume retroperitoneal lymphadenopathy. (bvsalud.org)
  • Testicular ultrasonography (also called scrotal ultrasonography) is the primary diagnostic modality for the evaluation of testicular and scrotal disease. (medscape.com)
  • Evaluation of scrotal pain, including but not limited to testicular trauma, ischemia/torsion, and infectious or inflammatory scrotal disease. (medscape.com)
  • Conclusion Testicular cancer is a rare disease which mainly affects young Malay males. (usm.my)
  • Young men with back pain should be examined for testicular disease and should also be asked about past testicular abnormalities. (ox.ac.uk)
  • USG is also helpful for follow up After explaining the procedure to patients in their vernacular language and orchidectomy for recurrent testicular obtaining consent from them, procedure neoplasm, staging the malignant disease were started. (gotomydoctor.com)
  • Mithramycin therapy in testicular cancer. (nih.gov)
  • In this investigation we studied the concentrations of the sum of 38 polychlorinated biphenyls (PCBs), p,p'-dichlorodiphenyl-dichloroethylene, hexachlorobenzene (HCB), and chlordanes, in 61 cases with testicular cancer and 58 age-matched controls. (nih.gov)
  • Three cases with testicular rupture were diagnosed accurately, with interruption of the dark signal intensity line of the tunica albuginea being pathognomonic for the diagnosis of testicular rupture. (medscape.com)
  • The American Institute of Ultrasound in Medicine has published guidelines (in association with the American College of Radiology, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound) on the evaluation of testicular and extratesticular structures. (medscape.com)
  • Association between polymorphisms in the aryl hydrocarbon receptor repressor gene and disseminated testicular germ cell cancer. (lu.se)
  • In the Western world, testicular germ cell cancer (TGCC) is the most common malignancy of young men. (lu.se)
  • According to all major guidelines, ultrasonography (US) is the imaging modality of choice for the diagnosis of testicular trauma. (medscape.com)
  • An adenomatoid tumor is a benign neoplasm of mesothelial origin that can be found in both female and male genital tracts, but it is more commonly found in the male adnexa, where it is the most common benign neoplasm. (medscape.com)
  • Scrotal skin lymphatics are different from testicular lymphatics and drain into the inguinal nodes. (medscape.com)
  • [ 5 ] Testicular ultrasonography has a wide range of applications, varying from acute scrotal pain to more chronic and nonspecific symptoms. (medscape.com)
  • Typically, scrotal and testicular ultrasonography are not associated with any complications. (medscape.com)
  • Although scrotal examination combined with testis tumor marker assessments is essential for optimal patient management, the possibility of a burned-out testicular tumor with normal scrotal examination should always be kept in mind. (tjtes.org)
  • The epithelial neoplasms have occurred in older dogs compared to those of other histogenic origins (mesenchymal and other origins/round cells). (bvsalud.org)
  • The frequency was 48% of epithelial neoplasms, 32% of mesenchymal neoplasms, and 10% of neoplasms with other origins and round cells. (bvsalud.org)
  • The prognosis for dogs with treated testicular cancer is usually very good. (furrycritter.com)
  • Testicular lymphatics follow the vessels of the spermatic cord through the inguinal canal and into the retroperitoneum. (medscape.com)
  • No consistent different risk pattern was found for seminoma or nonseminoma testicular cancer. (nih.gov)
  • 6. [Bilateral and synchronic testicular neoplasia. (nih.gov)
  • Evaluation of palpable inguinal, intrascrotal, or testicular masses. (medscape.com)
  • Testicular cancer incidence rate has risen globally over the past several decades, with the average increase in the incidence of testicular cancer in Croatia of 7% per annum from the year 1983 to 2007. (nih.gov)
  • An increasing incidence of testicular cancer has been reported from several countries in the Western world during the last decades. (nih.gov)
  • 17. Appendix 9: Testicular seminoma and non-seminoma: eUpdate published online 29 June 2017 (www.esmo.org/Guidelines/Genitourinary-Cancers). (nih.gov)
  • This results in hypoplasia or absence of Leydig cells, testicular atrophy, and lower than normal androgen levels. (wikipedia.org)
  • Background Testicular cancer is a rare malignancy worldwide, especially among Asians. (usm.my)
  • Treatment with radiation is linked to some second cancers after testicular cancer. (cancer.org)
  • Malignant testicular neoplasms constitute about 1% of all cancers in males. (ecancer.org)
  • 14. Coexistence of 2 malignant urogenital neoplasms: a testicular seminoma and adenocarcinoma of the prostate gland in a patient 1 year after kidney transplantation. (nih.gov)
  • The neoplasms most frequently observed, in decreasing order of frequency, were: adenocarcinoma (9/50), squamous cell carcinoma (9/50), transmissible venereal tumor (5/50), osteosarcoma (5/50), chondrosarcoma (4/50), and undifferentiated sarcoma (4/50). (bvsalud.org)
  • Overall, the CGH analyses confirmed gains and losses of certain chromosomal regions in TGCT as observed by karyotyping, and thus support their role in the development of these neoplasms. (prinsesmaximacentrum.nl)
  • The right testicular vein drains into the inferior vena cava and the left testicular vein drains into the left renal vein. (freezingblue.com)
  • Here, using the 129.MOLF-Chr19 mouse model of testicular teratomas and a NANOS2 reporter allele, we report that the developmental phenotypes required for tumorigenesis, including failure to enter mitotic arrest, retention of pluripotency and delayed sex-specific differentiation, were exclusive to a subpopulation of germ cells failing to express NANOS2. (nih.gov)
  • The most common cancer seen in testicular cancer survivors is a second testicular cancer. (cancer.org)
  • Compared with most men in the general population, testicular cancer survivors are up to twice as likely to develop a new cancer outside the testicle. (cancer.org)
  • Time to correct diagnosis from first visit to a doctor was significantly longer in those with back pain than in those with testicular symptoms. (ox.ac.uk)
  • MRI identified 3 intraparenchymal hematomas, 1 intrascrotal cavernous body rupture, 1 testicular abscess with intrascrotal fistula, 2 testicular infarctions, and 15 neoplasms. (medscape.com)
  • This study aimed to quantify nasosinusal neoplasms diagnosed in dogs in 20 years (2000-2019) and characterize the main clinical, macroscopic, and histological aspects of these neoplasms. (bvsalud.org)
  • Through this study, it was possible to establish the frequency of these neoplasms in 20 years and their clinical, macroscopic, and histological characteristics. (bvsalud.org)
  • Testicular ultrasonography is a useful noninvasive tool in both adult and pediatric patient groups. (medscape.com)
  • In the clinical setting of testicular torsion , ultrasonography should not delay manual or surgical reduction. (medscape.com)
  • [ 10 ] In animal studies of acute testicular ischemia, pulse-wave spectral Doppler ultrasonography has been shown to assess perfusion better than conventional color flow Doppler or power Doppler methods. (medscape.com)
  • In recent years, radiation therapy for testicular cancer has changed. (cancer.org)
  • Dell'atti reported a case diagnosed with testicular ultrasound. (medscape.com)
  • Ultrasound may confirm or imply testicular rupture, which should prompt exploration and attempt at repair. (medscape.com)
  • 29] In the study, Doppler ultrasound revealed an inflammatory process in 277 patients, testicular trauma in 112, funicular torsion or torsion of the vestigial remnant in 44, and testicular neoplasm findings in 35. (medscape.com)
  • 10] Testicular rupture is a urologic emergency, and more than 80% of ruptured testes can be saved if surgery is performed within 72 hours. (medscape.com)