• Odontogenic keratocysts (OKCs) are developmental odontogenic cysts of epithelial origin, first identified and described in 1876 and further characterized by Phillipsen in 1956. (medscape.com)
  • Multiple odontogenic keratocysts (OKCs) are a well-recognized feature of NBCCS (see the image below). (medscape.com)
  • Odontogenic keratocysts (OKCs) associated with this syndrome have a familial tendency, and early family detection and genetic counseling are critical. (medscape.com)
  • Panoramic film demonstrating mandibular odontogenic keratocysts in nevoid basal cell carcinoma syndrome. (medscape.com)
  • Odontogenic keratocysts (OKCs) associated with NBCCS have occasionally been reported to transform into aggressive neoplasms such as ameloblastomas and squamous cell carcinoma . (medscape.com)
  • [ 13 ] Peripheral odontogenic keratocysts can be seen in association with NBCCS. (medscape.com)
  • Odontogenic keratocysts may occur in any part of the upper and lower jaw, with the majority (almost 70%) occurring in the mandible. (washington.edu)
  • Odontogenic keratocysts are significant clinical entities due to their tendency for recurrence and destructive behavior. (washington.edu)
  • OBJECTIVE: To investigate the expressions and clinicopathological features of glucose transporter 1 (GLUT-1), pyruvate kinase M2 (PK-M2) and hypoxia-inducible factor 1α (HIF-1α) in odontogenic keratocysts (OKCs), and to investigate the mutation status of v-raf murine sarcoma viral oncogene homolog B1 (BRAF). (bvsalud.org)
  • A glandular odontogenic cyst (GOC) is a rare and usually benign odontogenic cyst developed at the odontogenic epithelium of the mandible or maxilla. (wikipedia.org)
  • Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic lesion, with debatable histogenesis and variable histopathology. (ac.ir)
  • Another origin is a primordial cyst that infiltrates the glandular epithelial tissue through a highly organised cellular differentiation. (wikipedia.org)
  • [ 2 ] The initial terminology for an odontogenic keratocyst (OKC) was "primordial cyst," as the origin of the lesion was thought to be the tooth primordium. (medscape.com)
  • Odontogenic Keratocyst (Primordial cyst) is known amongst clinicians for its peculiar behaviour, origin of varied nature, discussions regarding its development and a unique tendency to recur. (ihrjournal.com)
  • [ 14 ] In recent years, the WHO has recommended that the term "keratocystic odontogenic tumor" (KCOT) replace the term "odontogenic keratocyst" (OKC), as it better reflects the neoplastic nature of the lesion. (medscape.com)
  • There is debate over reclassification of the odontogenic keratocyst (OKC) as keratocystic odontogenic tumor (KCOT). (easynotecards.com)
  • The recurrence rate of 112 cases of Keratocystic Odontogenic Tumor (KCOT) were analyzed with regard to their location, size, locularity and treatment. (clinmedjournals.org)
  • The Keratocystic Odontogenic Tumor (KCOT) is characterized by its high tendency to recur after surgical treatment. (clinmedjournals.org)
  • Keratocystic Odontogenic Tumor: Case Reports and Review of Literature. (ihrjournal.com)
  • The differential diagnosis of these lesions includes cystic ameloblastoma, adenomatoid odontogenic tumor, odontogenic calcification cyst 7 . (bvsalud.org)
  • Adenomatoid odontogenic tumor (AOT) was first elucidated by Driebaldt in 1907 as "pseudo-adenoameloblastoma," and later as "adenomatoid odontogenic tumor. (ac.ir)
  • OKCs can also present as small and oval radiolucencies between teeth simulating a lateral periodontal cyst, in an area of an extracted tooth simulating a residual cyst, at the apex of a vital tooth mistaken for a periapical cyst, or in the anterior maxilla between the central incisors simulating an incisive canal cyst (2). (washington.edu)
  • OKCs grow to sizes larger than any other odontogenic cysts. (washington.edu)
  • Analysis of scans allow for the differentiation of GOC from other parallel lesions, i.e. "ameloblastoma, odontogenic myxoma, or dentigerous cyst" in order to minimise the chance of a misdiagnosis. (wikipedia.org)
  • Ameloblastoma is one of the most common benign neoplasms of odontogenic origin. (washington.edu)
  • The odontogenic keratocyst (OKC) is known for its high recurrence rate, aggressive behavior, and its occasional association with the nevoid basal cell carcinoma syndrome (NBCCS). (medscape.com)
  • The less aggressive clinical behavior and recurrence pattern of the orthokeratinized variant ultimately warranted the designation of the orthokeratinized variant as a separate entity, "orthokeratinized odontogenic cyst" (OOC). (medscape.com)
  • What is the most common type of developmental odontogenic cyst? (easynotecards.com)
  • It draws attention to the fact that several developmental processes occur in the maxillofacial area during childhood, including bone growth and odontogenesis,which could be associated with cyst formation 8 . (bvsalud.org)
  • Odontogenic cysts are a group of common pathological lesions of the jaw. (intechopen.com)
  • To investigate the distribution of odontogenic cysts in patients aged 0 to 18, referred to Department of Pathology, University Hospital of the Federal University of Maranhão, Brazil, to determine the most common types of lesions and their distribution according to gender and anatomical site involved. (bvsalud.org)
  • Histopathological data were collected from a database of lesions classified as odontogenic cysts that were indicated for surgical removal and histopathological analysis. (bvsalud.org)
  • These cysts constitute an important group of lesions in the maxillofacial complex, whose frequency varies from 7 to 13% of lesions diagnosed in this anatomic region 2-3 , affecting mainly the adult population 2,4 . (bvsalud.org)
  • These lesions are characterized by having slow growth and tendency to expand, despite the biological behavior of benign entities. (bvsalud.org)
  • Most cysts recur within the first three years while others may recur as late as after 16 years (1, 2). (washington.edu)
  • This is attributed to its infiltrative growth pattern and to the failure during surgery to remove the epithelial rests of the dental lamina or the daughter cysts [ 1 - 4 ]. (clinmedjournals.org)
  • The cyst was excised, and histopathologic examination revealed an odontogenic keratocyst (OKC). (easynotecards.com)
  • The sample included all medical records with a histopathologic diagnosis of odontogenic cyst, as defined by the Medical Subject Headings - Mesh, of patients aged 0 to 18 referred to the service above, diagnosed during the period from 1990 to 2010. (bvsalud.org)
  • blood t. term sometimes used to denote an aneurysm , hemorrhagic cyst , or hematoma . (en-academic.com)
  • Gross specimen of a cyst involving a maxillary canine tooth. (easynotecards.com)
  • A unilocular radiolucent cyst involving the crown of an unerupted tooth, with the crown projecting into the cystic cavity. (easynotecards.com)
  • A unilocular radiolucent cyst extending along the mesial and distal roots of the unerupted tooth. (easynotecards.com)
  • Odontogenic cysts are pathological entities that correspond to cavities lined with epithelial tissue, containing in its interior semi solid or liquid material, whose formation is associated with proliferation of epithelial remnants of the enamel organ or even the development of embryonic processes maxillomandibular 1 . (bvsalud.org)
  • A potential biological origin of GOC is a cyst developed at a salivary gland or simple epithelium, which undergoes maturation at the glandular. (wikipedia.org)
  • 1 The World Health Organization (WHO) in 2005 defined AOT as a tumor composed of odontogenic epithelium, presenting a variety of histo-architectural patterns, embedded in mature connective tissue stroma, and characterized by slow and progressive growth. (ac.ir)
  • In cases of large cysts, an incisional biopsy was first performed, and taking into consideration the proximity of the tumor to vital structures that needed to be preserved and the degree of cooperation of the patient, a decision was made regarding the mode of treatment: enucleation with peripheral ostectomy or marsupialization followed by enucleation with peripheral ostectomy in both modalities with or without the use of Carnoy's solution. (clinmedjournals.org)
  • This odontogenic cyst is commonly described to be a slow and aggressive development. (wikipedia.org)
  • Odontogenic keratocyst is an aggressive cyst known for its rapid growth and its tendency to invade the adjacent tissues, including bone. (washington.edu)
  • Some investigators advocate marsupialization and occasionally resection of the more aggressive cysts that tend to perforate buccal and lingual bone. (washington.edu)
  • It accounts for 11% of all odontogenic neoplasms/hamartomas (4-6). (washington.edu)
  • A unilocular radiolucent cyst along the mesial root of the unerupted molar. (easynotecards.com)
  • This inflamed cyst shows a thick epithelial lining with hyperplastic rete ridges and diffuse chronic inflammatory infiltrate. (easynotecards.com)
  • neoplastic cells are frequently palisaded at the periphery of the small groups, and the latter have a tendency to infiltrate surrounding tissue . (en-academic.com)
  • Odontogenic keratocyst predominantly affects Caucasian populations and, if one may judge from the limited evidence provided by the literature, is chiefly of Northern European descent (1). (washington.edu)
  • Odontogenic cysts can be classified as to their etiology in inflammation and development, and are differentiated by histopathology, mainly because the clinical and radiographic characteristics are very similar. (bvsalud.org)
  • These cysts can occur singly or multiply, as a part of Nevoid Basal Cell Carcinoma Syndrome (NBCCS). (ihrjournal.com)
  • [ 5 ] Usually, odontogenic keratocyst (OKC) development, which comprises one of the major criterions, occurs before the observation of other clinical findings in NBCCS, enhancing early diagnosis of the disease. (medscape.com)
  • [ 9 ] These cysts arise earlier in patients with NBCSS than in those who are unaffected by the syndrome. (medscape.com)
  • GOC was established as its own biological growth after differentiation from other jaw cysts such as the "central mucoepidermoid carcinoma (MEC)", a popular type of neoplasm at the salivary glands. (wikipedia.org)
  • Nevertheless, the literature on odontogenic cysts includes studies mainly in the adult population, with few studies in children and adolescents. (bvsalud.org)
  • Treatment modes of the GOC follow a case-by-case approach due to the variable nature of the cyst. (wikipedia.org)
  • 40 y) may have a lower prevalence of BCC on the head and neck and a higher prevalence on the trunk, with greater tendency to superficial BCC, than in older patients. (medscape.com)
  • Often a cyst can form around a variety of structures in the mouth. (oasisdentalarts.com)
  • It reduces the tendency for the skin to stick to any underlying structures and is thought to speed up the healing process, reducing the redness and irregularity. (exodontia.info)
  • A cyst is located in the third molar area in a patient with no history of third molar extraction. (easynotecards.com)