• genes
  • To date, nine mucin genes have been identified. (bmj.com)
  • Clusters of genes in close proximity and high transcription levels can easily been generated by tandem duplicates. (wikipedia.org)
  • Their scarcity in RIDGEs can be explained by the fact that natural selection favors the scarcity of LINE repeats in ORFs because their endonuclease sites can cause deleterious mutation to the genes. (wikipedia.org)
  • amino
  • Mature mucins are composed of two distinct regions: The amino- and carboxy-terminal regions are very lightly glycosylated, but rich in cysteines. (wikipedia.org)
  • mucosal
  • The dense "sugar coating" of mucins gives them considerable water-holding capacity and also makes them resistant to proteolysis, which may be important in maintaining mucosal barriers. (wikipedia.org)
  • MUC21
  • Homo sapiens mucin 21, cell surface associated (MUC21), mRNA. (usc.edu)
  • AB242595 - Homo sapiens MUC21 mRNA for mucin 21, complete cds. (usc.edu)
  • abnormal
  • These human mucin probes may be important in assessing the abnormal mucins associated with inflammatory diseases or carcinoma from human mucosae. (biochemj.org)
  • Abnormal deposits of mucin are responsible for the non-pitting facial edema seen in untreated hypothyroidism. (wikipedia.org)
  • tumor
  • Within the peripheral regions, sequence variations 1-4 occur at high incidence and show a nearly constant repeat topology in all individual normal and tumor samples. (semanticscholar.org)
  • The repeat variant 1 replacing the established tumor target motif DTR with ESR was found in all individuals and appears predominantly in repeat clusters (diads and triads). (semanticscholar.org)
  • human
  • Minisatellite variant repeat analyses were performed with 27 individual samples of genomic DNA from human cells and tissues covering 30-60% of the domain. (semanticscholar.org)
  • cDNA
  • BC105735 - Homo sapiens mucin 21, cell surface associated, mRNA (cDNA clone MGC:125612 IMAGE:40026480), complete cds. (usc.edu)
  • BC105736 - Homo sapiens mucin 21, cell surface associated, mRNA (cDNA clone IMAGE:40026479), complete cds. (usc.edu)
  • BC107478 - Homo sapiens mucin 21, cell surface associated, mRNA (cDNA clone MGC:125609 IMAGE:40026469), complete cds. (usc.edu)
  • expression
  • The expression of mucin 16 has been shown to be altered in dry eye, cystic fibrosis, and several types of cancers. (wikipedia.org)
  • No significant association was found between the expression of these mucins and tumour size, histological grade, node status, oestrogen receptor status, p53 positivity, or c-ErbB-2 overexpression. (bmj.com)
  • high
  • High levels of under-glycosylated Mucin 1 are thought to affect cell behavior during both invasion and metastasis as well as in immune recognition. (fishersci.no)