Trna biosynthesis of peptides and proteins on ribosomes protein biosynthesis. Medical search. Frequent questions

The small ribosomal subunit matches the codons of the mRNA which is present in the tRNAs. (microbenotes.com)
Ribosome protects the mRNA strand from the nuclease enzyme. (microbenotes.com)
The mRNA during the translation process lies in between the larger and smaller subunit of the ribosome. (microbenotes.com)
Stepwise addition of amino acids to the growing polypeptide chain requires the coordinated movement of mRNA and tRNAs through the ribosome, a process known as translocation. (ox.ac.uk)
Here, we review current understanding of the kinetics and mechanics of translocation, with particular emphasis on the structure of a functional mammalian ribosome stalled during translocation by an mRNA pseudoknot. (ox.ac.uk)
ETFL formulates a mixed-integer linear problem (MILP) that enables both relative and absolute metabolite, protein, and mRNA concentration integration. (nature.com)
It also accounts for growth-dependent parameters, such as relative protein or mRNA content. (nature.com)
It is typically discussed using the "codons" found in mRNA, as mRNA is the messenger that carries information from the DNA to the site of protein synthesis. (mercinewyork.com)
Because alternative RNA splicing allows different types of mRNA molecules to be created from a single gene, it generates the diversity of protein function and structure that is essential to complex organisms. (genomicglossaries.com)
More than half of all human genes are alternatively spliced, so it is expected that alternative pre- mRNA splicing will be responsible for the identification of more than 90 percent of all human proteins. (genomicglossaries.com)
Highly specific and effective gene silencing of any disease can be achieved by an accurate knowledge of the target mRNA sequence and rational design of its complementary antisense agents for the downregulation of its protein message. (genomicglossaries.com)
Steps in protein synthesis: step 1: the first step in protein synthesis is the transcription of mrna from a dna gene in the nucleus. (leedonss.com)
Proteins shown in red (FDR 0.01) represent the mRNA interactome. (nature.com)
c ) Overlap of mRNA interactome proteins in yeast and HuH-7. (nature.com)
d ) Validation of the yeast mRNA interactome using western blotting of input samples and eluate after interactome capture with specific antibodies (ADH1, alcohol dehydrogenase 1, PUB1) or against TAP-tagged proteins (PGK1, phosphoglycerate kinase 1, TDH1, triose phosphate dehydrogenase, TRX2, thioredoxine 2, SHE2, Swi5p-dependent HO Expression 2). (nature.com)
B) The translational machinery depends on the translocation along the mRNA whereby a new acetylated-tRNA is positioned in the ribosome. (biomedcentral.com)

Redirecting RiPP Biosynthetic Enzymes to Proteins and Backbone-Modified Substrates. (schepartzlab.com)
Furthermore, the transcriptional responses of B5 at different temperature by using rice straw as sole carbon sources were also analyzed, based on which the mechanism of lignocellulose degradation at high temperature was revealed that B5 could resist the heat by up-regulating the heat shock proteins (HSP) and then secrete various Carbohydrate-Active enzymes (CAZymes) to realize energy balance. (researchsquare.com)
4 , to model the proteome-related limitations of the cell, as enzymes have to compete for the constrained total amount of cellular proteins. (nature.com)
Under this hypothesis, any model for the emergence of the genetic code is intimately related to a model of the transfer from ribozymes (RNA enzymes) to proteins as the principal enzymes in cells. (mercinewyork.com)
Only 60% of yeast and 73% of the human RBPs have functions assigned to RNA biology or structural motifs known to convey RNA binding, and many intensively studied proteins surprisingly emerge as RBPs (termed 'enigmRBPs'), including almost all glycolytic enzymes, pointing to emerging connections between gene regulation and metabolism. (nature.com)
We show that this conserved RNA interactome harbours many proteins without previously assigned roles in RNA biology (enigmRBPs), including surprisingly many metabolic enzymes. (nature.com)
The co-occurrence analysis of core concepts in this stringent response, i.e. the (p)ppGpp nucleotides with gene products was also inspected and suggest that besides the enzymes RelA and SpoT that control the basal levels of (p)ppGpp nucleotides, many other proteins have a key role in this response. (biomedcentral.com)
Such accumulation is known to be controlled by the activity of two enzymes, the ribosome-bound RelA enzyme (ppGpp synthetase I) that synthesises (p)ppGpp nucleotides upon the depletion of amino acids [ 19 ] and the bifunctional SpoT enzyme (ppGpp synthetase II) that is responsible for maintaining the intracellular levels of (p)ppGpp nucleotides via enzymatic degradation [ 20 ]. (biomedcentral.com)

Within the ribosome, the rrna molecules direct the catalytic steps of protein synthesis - the stitching together of amino acids to make a protein molecule. (thecosmictreehouse.com)

In the online version, these sections contain links to more information about proteins encoded by over 17,000 known or predicted human genes. (cshlpress.com)
The mitochondrial tRNA genes are hot spots for mutations that lead to human disease. (ncsu.edu)
Considerable interest in mitochondrial tRNAs centers on the occurrence of diseases arising from mutations in their genes that lead to maternally inherited genetic disorders (9Wittenhagen L.M. Kelley S.O. Trends Biochem. (ncsu.edu)
Sequence and primer extension analysis revealed the presence of putative genes encoding tRNA lle and tRNA Ala within the 16S-23S spacer region, as well as a number of potential regulatory features. (microbiologyresearch.org)
Indeed, the identification of biologically relevant concepts in free text, namely genes, tRNAs, mRNAs, gene products and small molecules, is crucial to capture the structure and functioning of different responses. (biomedcentral.com)

A Disease-causing Point Mutation in Human Mitochondrial tRNA(Met) Results in tRNA Misfolding Leading to Defects in Translational Initiation and Elongation. (ncsu.edu)
The hmtRNAMet serves both in translational initiation and elongation in human mitochondria making this tRNA of particular interest in mitochondrial protein synthesis. (ncsu.edu)
104: 15299-15304Crossref PubMed Scopus (38) Google Scholar), and from the failure of the tRNA to be correctly modified leading to translational defects (18Kirino Y. Yasukawa T. Ohta S. Akira S. Ishihara K. Watanabe K. Suzuki T. Proc. (ncsu.edu)
As a result of this dual role, mitochondrial Met-tRNAMet must be recognized by the mitochondrial Met-tRNA transformylase (MTFmt) and be brought as fMet-tRNAMet to the ribosome for translational initiation (19Spencer A.C. Spremulli L.L. Nucleic Acids Res. (ncsu.edu)
In addition, Met-tRNAMet must interact with elongation factor EF-Tumt and bind to the A-site of the ribosome during translational elongation. (ncsu.edu)
Other papers discuss messenger rna and its translation, dna-dependent cell-free protein synthesis, as well as the genetics of the translational apparatus. (leedonss.com)
In genetic and biochemical studies, we found that the mutation disrupts eIF2 complex integrity, impairs general translation, alters translational control of mRNAs encoding key regulatory proteins, and reduces the fidelity of translation start codon selection. (nih.gov)

The mechanism of action of macrolides is inhibition of bacterial protein biosynthesis, and they are thought to do this by preventing peptidyltransferase from adding the growing peptide attached to tRNA to the next amino acid (similarly to chloramphenicol) as well as inhibiting bacterial ribosomal translation. (wikipedia.org)
Macrolide antibiotics bind reversibly to the P site on the 50S subunit of the bacterial ribosome. (wikipedia.org)
In the case of the bacterial ribosome, adding about 20 amino acids in one second. (microbenotes.com)
Structure of the bacterial ribosome at 2 Å resolution. (schepartzlab.com)
Expression of recombinant proteins using bacterial, animal and plant vectors. (aadharinstitute.com)

Then the ribosome translates its nucleotide sequence into an amino acid sequence, one codon at a time. (microbenotes.com)
We have identified a cytosolic acyl-CoA binding protein, with highly conserved amino acid residues and a typical acyl-CoA binding domain in N. caninum . (biomedcentral.com)
In protein biosynthesis acyl-transfer ribonucleic acids (trna's) were used as amino acid precursors. (leedonss.com)
A) Low amino acid concentrations lead to decreased charging of the corresponding tRNAs. (biomedcentral.com)
A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. (lookformedical.com)
An essential branched-chain aliphatic amino acid found in many proteins . (lookformedical.com)
An unnatural amino acid that is used experimentally to study protein structure and function. (lookformedical.com)

Protein conformation is critically linked to function and often controlled by interactions with regulatory factors. (cipsm.de)
Here we report the selection of camelid-derived single-domain antibodies (nanobodies) that modulate the conformation and spectral properties of the green fluorescent protein (GFP). (cipsm.de)
In the context of a pseudoknot-stalled complex, the translocase EF-2 is seen to compress a hybrid-state tRNA into a strained conformation. (ox.ac.uk)
It is of fundamental importance in determining PROTEIN CONFORMATION . (lookformedical.com)

To determine the biochemical consequence of the 8U→C mutation, the abilities of the U8 and 8U→C hmtRNAMet transcripts to be aminoacylated by the human mitochondrial methionyl-tRNA synthetase (hmMetRS) were tested. (ncsu.edu)
Of special interest are the translation initiation factors eIF2, a GTPase that binds methionyl-tRNA to the ribosome, and eIF5B, a second GTPase that catalyzes ribosomal subunit joining in the final step of translation initiation. (nih.gov)

The eukaryotic cell in its cytoplasm contains millions of ribosomes. (microbenotes.com)
The ribosome of the bacteria performs faster than the eukaryotic ribosome. (microbenotes.com)
We determined subnanometer-resolution cryo-electron microscopy structures of eukaryotic ribosome-Sec61 complexes. (cipsm.de)
In many cases, they lack a number of the conserved or semi-conserved nucleotides that play important roles in creating the L-shaped tertiary structure of prokaryotic and eukaryotic cytoplasmic tRNAs (3Dirheimer G. Keith G. Dumas P. Westhof E. RajBhandary U. Soll D. tRNA: Structure, Biosynthesis and Function. (ncsu.edu)

Crystal structures of tRNA mimics complexed with the large ribosomal subunit of Deinococcus radiodurans indicate that remote interactions determine the precise orientation of tRNA in the peptidyl-transferase center (PTC). (cnr.it)
The first step of protein synthesis is binding of the initiator Met-tRNA to the small ribosomal subunit by the factor eIF2, which is composed of three subunits. (nih.gov)
Phosphorylation of the eIF2alpha subunit is a common mechanism for down-regulating protein synthesis under stress conditions. (nih.gov)

Before entering lipid synthesis pathways, different kinds of acyl-CoA transporters which acts as the major carrier of acyl-CoAs, such as fatty acid binding protein (FABP), sterol carrier protein 2 (SCP2) and acyl-CoA-binding protein (ACBP), would activate and convert fatty acids to fatty acyl-CoA esters via a reaction catalyzed by fatty acyl-CoA synthetase and transported to various metabolic locations [ 11 ]. (biomedcentral.com)

Preexisting antivector immunity can severely compromise the ability of Salmonella enterica serovar Typhimurium live vaccines to induce protective CD8 T-cell frequencies after type III secretion system-mediated heterologous protein translocation in orally immunized mice. (cipsm.de)
We propose that this strain energy helps overcome the kinetic barrier to translocation and drives tRNA into the P-site, with EF-2 biasing this relaxation in one direction. (ox.ac.uk)
The tRNA can thus be considered a molecular spring and EF-2 a Brownian ratchet in a "spring-and-ratchet" system within the translocation process. (ox.ac.uk)
H69, the intersubunit-bridge connecting the PTC and decoding site, may also participate in tRNA placement and translocation. (cnr.it)
A spiral rotation of the 3′ end of the A-site tRNA around a 2-fold axis of symmetry identified within the PTC suggests a unified ribosomal machinery for peptide-bond formation, A-to-P-site translocation, and entrance of nascent proteins into the exit tunnel. (cnr.it)

The ribosomes present in mitochondria and chloroplasts are smaller than 80S cytoplasmic ribosomes. (microbenotes.com)
The co-localization of BmHSP60 candidate interaction proteins with mitochondria was analyzed by Mito-Tracker-Green. (chinaagrisci.com)
Conclusion】 Heat shock protein BmHSP60 of B. mori was identified to interact with BmANT and BmHSP90, and co-localized in mitochondria. (chinaagrisci.com)
In particular, a number of the long range interactions between the D- and T-arms of the tRNAs appear to be missing.All 22 tRNAs that function in mammalian mitochondria are encoded in the mitochondrial DNA. (ncsu.edu)
Aminoacylation is an early step required for the tRNA to be used in either the elongation or initiation phase of protein synthesis and is thus of central importance for protein synthesis in mitochondria. (ncsu.edu)
Structure and function of cell and cytoplasmic constituents: Structure of nucleus, mitochondria, Golgi bodies, endoplasmic reticulum, lysosomes and ribosomes. (aadharinstitute.com)

However, chemical and enzymatic probing has lead to the idea that these tRNAs have retained the basic cloverleaf structure of canonical tRNAs but that they lack several conserved tertiary interactions leading to a weaker three-dimensional structure (4Watanabe Y.-I. Kawai G. Yokogawa T. Hayashi N. Kumazawa Y. Ueda T. Nishikawa K. Hirao I. Miura K.-I. Watanabe K. Nucleic Acids Res. (ncsu.edu)
The diseases associated with mitochondrial tRNA mutations may arise from failure in the processing of the tRNA (13Levinger L. Jacobs O. James M. Nucleic Acids Res. (ncsu.edu)
It seems that not until the technologies for working with nucleic acids and proteins are better integrated will their researchers be more connected than they are now. (genomicglossaries.com)

Additional links to NCBI resources are provided for human noncoding RNAs and repeated DNA elements and for proteins of interest from other species. (cshlpress.com)
After cell lysis, polyadenylated RNAs were captured on oligo d(T) beads followed by stringent washes to remove non-crosslinked proteins. (nature.com)

The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. (cipsm.de)
8, 9] STAT3 is one of 7 human STAT (signal transducer and activator of transcription) proteins, which are critical second messengers for many cytokine, hormone, and growth factor receptors. (medscape.com)

Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs. (uni-frankfurt.de)
FBA also fails to capture growth-dependent and protein-level effects, such as enzyme saturation or proteome-related limitations. (nature.com)
This download is the types and cells led from a human assembly target content soccer methylated alongside the set of two interaction localizing enzyme proteins in New Zealand. (evakoch.com)

Basic sequence-derived (length, molecular weight, isoelectric point) and experimentally-determined (median abundance, median absolute deviation) protein information. (yeastgenome.org)
The 5 bands were mixed into a protein pool for mass spectrometry, and 5 interaction proteins were screened consistent with the differential bands in silver staining according to the number of peptides and molecular weight of proteins. (chinaagrisci.com)
We have used structural probing and molecular reconstitution experiments to examine the structures formed by the normal and mutated tRNAs. (ncsu.edu)

The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS . (lookformedical.com)
A transfer RNA which is specific for carrying leucine to sites on the ribosomes in preparation for protein synthesis. (lookformedical.com)

No data are currently available that examine the structure of mammalian mitochondrial tRNAs with single nucleotide resolution. (ncsu.edu)

12] These errors, mutations, can affect an organism's phenotype, especially if they occur within the protein coding sequence of a gene. (mercinewyork.com)
RNA-binding proteins (RBPs) mediate pivotal cellular functions such as RNA transport, degradation or translation and represent key effectors of post-transcriptional gene regulation. (nature.com)

The translation of genetic information into proteins is a fundamental process of life. (ox.ac.uk)
The minigenome's genetic material by itself is not infectious, because viral proteins, among them the RNA-dependent RNA polymerase, are necessary to transcribe the viral genome into mRNAs because it is a negative sense RNA virus, as well as for replication of the viral genome. (ebolavirusnet.com)

Another potential mechanism is premature dissociation of the peptidyl-tRNA from the ribosome. (wikipedia.org)
Ribosomes functions as catalysts during peptidyl transfer and peptidyl hydrolysis. (microbenotes.com)
The role of this modification in (hmtRNAMetCAU) for the decoding of AUA, as well as AUG, in both the peptidyl- and aminoacyl-sites of the ribosome in either chain initiation or chain elongation is still unknown. (ncsu.edu)
We are characterizing eIF2gamma mutations that are associated with a novel X-linked intellectual disability syndrome, and we are investigating the function of the translation factor eIF5A with a focus on its ability to stimulate the peptidyl transferase activity of the ribosome and facilitate the reactivity of poor substrates such as proline. (nih.gov)

Macrolides are protein synthesis inhibitors. (wikipedia.org)

In the 80S ribosome of yeast, 79r-protein are present where only 12 r-protein are found to be specific. (microbenotes.com)
The recombinant NcACBP protein was expressed to verify the binding activities of NcACBP in vitro , and the heterologous expression of NcACBP in Δacbp yeast in vivo . (biomedcentral.com)

This modification may play a role in the unusual codon recognition requirements of this tRNA, which must recognize both AUG and AUA codons. (ncsu.edu)
The modification uridine-5-oxyacetic acid (cmo (5)U 34) is found at wobble position 34 in a single isoaccepting tRNA species for six amino acids, alanine, leucine, proline, serine, threonine, and valine, each having 4-fold degenerate codons. (ncsu.edu)
cmo (5)U 34 makes possible the decoding of 24 codons by just six tRNAs. (ncsu.edu)
As a result, the ribosome stops working on that protein and all subsequent codons are not transcribed! (mercinewyork.com)

Artist's rendering of the protein synthesis process, in which a trna molecules carry amino. (thecosmictreehouse.com)
This doesn't matter in RNA, since new RNA copies can be produced from DNA at any time, and most RNA molecules are intentionally destroyed by the cell a short time after they're produced so that the cell does not waste resources producing unneeded proteins from old RNA molecules. (mercinewyork.com)

Plastid-specific ribosomal proteins (PSRPs) have been proposed to play roles in the light-dependent regulation of chloroplast translation. (cipsm.de)
Expression of the Escherichia coli tryptophanase operon depends on ribosome stalling during translation of the upstream TnaC leader peptide, a process for which interactions between the TnaC nascent chain and the ribosomal exit tunnel are critical. (cipsm.de)
Translation elongation factors are the workhorses of protein synthesis on the ribosome. (leedonss.com)

The protease not only releases small peptides, such as the amyloid-β peptide, which drives Alzheimer's disease pathogenesis, but also intracellular domains, which can have critical functions in nuclear signaling. (cipsm.de)
Membrane structure and function: Structure of model membrane, Lipid bilayer and membrane protein, diffusion, osmosis, ion channels, Active transport membrane pumps, mechanism of solving and regulations of intracellular transport, Electrical properties of membrane. (aadharinstitute.com)

Function of ribobomes in protein biosynthesis a occurrence of polysomes. (leedonss.com)

Beta-oxidative pathway of fatty acids, brief account of biosynthesis of triglycerides, cholesterol & its metabolism. (aadharinstitute.com)

Overview of protein biosynthesis in prokaryotes and eukaryotes. (leedonss.com)

This viral genome codes for seven structural proteins and one non-structural protein. (ebolavirusnet.com)

Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding. (ncsu.edu)
The contributions of this important modification to the structures and codon binding affinities of the unmodified and fully modified anticodon stem and loop domains of tRNA (Val3) UAC (ASL (Val3) UAC) were elucidated. (ncsu.edu)

Mammalian mitochondrial tRNAs have several unusual features that distinguish them from canonical tRNAs. (ncsu.edu)

The NcACBP recombinant protein was able to specifically bind acyl-CoA esters in vitro . (biomedcentral.com)
We previously showed that, despite their structural similarity, eIF2 and EF-Tu bind to tRNA in substantially different manners, and we showed that the tRNA-binding domain III of EF-Tu has acquired a new function in eIF2gamma to bind to the ribosome. (nih.gov)

Download DNA or protein sequence, view genomic context and coordinates. (yeastgenome.org)
The accuracy and efficiency with which tRNA decodes genomic information into proteins require posttranscriptional modifications in or adjacent to the anticodon. (ncsu.edu)

Objective】 HSP60 is an important member of heat shock proteins, which plays an important role in the innate immunity of insects, and is also an essential factor for insect growth and development. (chinaagrisci.com)

Before proteins are functional, a proper shape and destination are both necessary. (thecosmictreehouse.com)
Here we demonstrate that PSRP1 is not a bona fide ribosomal protein, but rather a functional homologue of the Escherichia coli cold-shock protein pY. (cipsm.de)
Functional recognition of the modified human tRNA(UUU)(Lys3) anticodon domain by HIV's nucleocapsid protein and a peptide mimic. (ncsu.edu)

The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. (lookformedical.com)

plasma biosynthesis has a preferred oxidase in the hydrolysis, leading its HC potential to have as a ichthyosis through which its LC apoptosis removes associated into the sufficient toxicity. (familie-vos.de)

We set out to analyze their pili-comprising proteins, pilins, because these extracellular proteins are in constant interaction with protons of the acidic medium in which At. (bvsalud.org)
The objective of this study is to identify the interaction proteins of BmHSP60, and to provide a basis for further exploring the mechanism in the innate immunity of B. mori . (chinaagrisci.com)
The antibody was incubated with the magnetic beads to capture the interaction proteins. (chinaagrisci.com)
The size of the bands was aligned with the NCBI database to screen for candidate interaction proteins according to the mass spectrometry results. (chinaagrisci.com)
Finally, the cloning vector of candidate interaction proteins was constructed and fused with HA tag, and transferred into B. mori cells with BmHSP60, respectively. (chinaagrisci.com)
Co-immunoprecipitation and fluorescence co-localization confirmed the interaction between BmHSP60 and candidate proteins. (chinaagrisci.com)
The BmHSP60 candidate interaction protein clone expression vector was constructed and fused with HA tag, and co-transfected with BmHSP60 into B. mori cells. (chinaagrisci.com)

Later, due to the aggregation of a large number of ribosomes, there is the formation of the polyribosomes or polysomes. (microbenotes.com)

The trimeric Sec61/SecY complex is a protein-conducting channel (PCC) for secretory and membrane proteins. (cipsm.de)
Substantial sequence differences (at least 12 non-synonymous SNP/kb) were found in 3.6% of the orthologs, and this set was enriched in cytochromes and integral membrane proteins. (biomedcentral.com)
The outer viral envelope of the virion is derived by budding from domains of host cell membrane into which the GP spikes have been inserted during their biosynthesis. (ebolavirusnet.com)

Our research centers on the chemistry, biochemistry and genetics of the biosynthesis of these secondary metabolites. (ufl.edu)

LMWH differs from unfractionated heparin in that it is less bound to plasma proteins. (medicosplexus.com)
Adsorption of plasma proteins on uncoated PLGA nanoparticles. (uni-frankfurt.de)

The mitochondrial genome encodes 13 proteins necessary for energy production, two rRNAs and all of the 22 tRNAs required for the synthesis of these proteins (1Attardi G. Int. Rev. Cytol. (ncsu.edu)

It was found that E. coli consists of 55 ribosomal proteins. (microbenotes.com)
The protein was purified as described for the E. coli MetRS except that the buffers contained 50 mm Tris-HCl, pH 7.6. (ncsu.edu)
Interestingly, whereas the 8U→C hmtRNAMet was poorly aminoacylated by the hmMetRS, it was not aminoacylated at all by the E. coli MetRS (Fig. 1C) suggesting that the mutated tRNA had a significantly altered structure. (ncsu.edu)
However, this work demonstrates that the hmMetRS is less discriminatory than E. coli MetRS for the structure of the tRNA. (ncsu.edu)

We study the mechanism and regulation of protein synthesis, focusing on GTPases and protein kinases that control this fundamental cellular process. (nih.gov)

Candidate proteins were ADP/ATP translocase (ANT), Actin, Alpha-tubulin, Elongation factor 1-alpha (EF-1 α ) and HSP90, respectively. (chinaagrisci.com)

high bacteria are as proteins of pathway ATM rise, either as acids for greenhouse initiation or for the dehydrogenase of binding eIF2 disorders. (evakoch.com)
The small fraction of hmtRNAMet that can be aminoacylated is not formylated by the mitochondrial Met-tRNA transformylase preventing its function in initiation, and it is unable to form a stable ternary complex with elongation factor EF-Tu preventing any participation in chain elongation. (ncsu.edu)

43: 9743-9754Crossref PubMed Scopus (38) Google Scholar) have shown that the transcript of mitochondrial tRNAMet has aminoacylation properties similar to those observed with the native tRNA. (ncsu.edu)
The defective aminoacylation of the 8U→C hmtRNAMet made it difficult to assess the effects of the mutation on additional steps in protein biosynthesis. (ncsu.edu)

route of disease proteins usually encodes between the critical cartContact phase of acid and a engineering cleavage of the transporter, although forms with percentage, guidance, and hospital mutations include structurally sustainable( reviewed in Wang et al. (familie-vos.de)

Principal Component Analysis (PCA) demonstrated that the protein patterns between PR and MF were more similar than ST. Differentially accumulated proteins (DAPs) analysis showed that there were 510, 173 and 514 DAPs in the comparisons of ST vs. PR, PR vs. MF and ST vs. MF, respectively. (peerj.com)
The differential strips were stored at -80℃, and then the differentially expressed peptides were analyzed by mass spectrometry. (chinaagrisci.com)
A total of 32 differentially expressed proteins were identified by comparing the results of silver-linked mass spectrometry with those of silkworm genome database and NCBI database. (chinaagrisci.com)

ELAC1 has been in the use and may as define as an RNase Z. In pyrophosphates subfamilies are transcribed from coupling tubules in the function by a two receptor chromatin that appears ultraviolet from protein threatening( reviewed in Popow et al. (evakoch.com)

Anatomy22

Organisms13

Chemicals and Drugs122

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Phenomena and Processes71

Disciplines and Occupations1

Information Science4

Health Care1

Mrna16

Enzymes8

Rrna1

Genes5

Translational7

Bacterial5

Amino acid7

Conformation4

Methionyl-tRNA2

Eukaryotic4

Subunit3

Synthetase1

Translocation5

Mitochondria6

Nucleic acids3

RNAs2

Transcription2

Enzyme3

Molecular3

Transfer Rna2

Nucleotide1

Gene2

Genetic2

Peptidyl4

Synthesis inhibitors1

Yeast2

Codons4

Molecules2

Translation3

Intracellular2

Occurrence1

Metabolism1

Prokaryotes1

Structural Proteins1

Codon2

Mammalian1

Bind2

Genomic2

Heat shock pr1

Functional3

Polypeptide1

Hydrolysis1

Interaction7

Polysomes1

Membrane3

Centers1

Plasma proteins2

Mitochondrial genome1

Coli4

GTPases1

Tubulin1

Initiation2

Aminoacylation2

Encodes1

Differentially3

Function1