• induction
  • Numerous immune regulatory functions have been reported for the IL-17 family of cytokines, presumably due to their induction of many immune signaling molecules. (wikipedia.org)
  • Toll-like receptor 2 stimulation predisposes for IL-10 production and induction of T regulatory lymphocytes Bartonella lipopolysaccharide is a non-toxic, complete blocker of Toll-like receptor 4 (TLR4) The fungal pathogen Candida albicans exhibits a series of molecular patterns that are recognised by different pattern recognition receptors. (wikipedia.org)
  • gene
  • In the BW5147 T cell line, we have identified two independent regulatory pathways by which arachidonic acid (20:4) can alter gene expression. (naver.com)
  • Interferon regulatory factor 4 also known as MUM1 is a protein that in humans is encoded by the IRF4 gene, located at 6p25-p23. (wikipedia.org)
  • Tolerance
  • It has been shown that transfer of tolerance to other recipients can be made without further manipulation and that this tolerance transfer depends only on CD4+ T-lymphocytes. (wikipedia.org)
  • intensity
  • After a transient increase during physical exercise of relatively high intensity, the number of circulating T lymphocytes often declines below the initial level after exercise ( 10 , 15 , 34 ). (physiology.org)
  • rejection
  • CD4+ and CD8+ T-lymphocytes along with other mononuclear leukocytes (their exact function regarding the topic is not known) participate in the rejection. (wikipedia.org)
  • interacts
  • It has been suggested recently that modulation of TfR and ferritin synthesis by iron is mediated through a cytoplasmic protein(s) (iron regulatory element-binding protein(s) (IRE-BP)), which interacts with ferritin and TfR mRNA at the level of hairpin structures (IRE), thus leading to inhibition of transferrin mRNA degradation and repression of ferritin mRNA translation. (epfl.ch)
  • expression
  • Thus exercise-elicited endogenous cortisol effectively augments CXCR4 expression on T lymphocytes, which may account for lymphopenia after exercise. (physiology.org)
  • activity
  • It is noteworthy the effect of beta-mercaptoethanol is cell specific, i.e. the ratio of total versus spontaneous IRE-BP activity is different in activated lymphocytes and maturing monocytes. (epfl.ch)
  • protein
  • By using the protein synthesis inhibitor, cycloheximide, we also show that the 20:4-mediated regulatory effects upon SCD2 or c- fos are completely independent of new protein synthesis. (naver.com)
  • type
  • Collectively, the results identify the existence of multiple, independent, intracellular 20:4-mediated regulatory pathways operating simultaneously within this cell type. (naver.com)