• cytokines
  • In this study, we thus investigated the expression of infiltrating lymphocyte subsets (CD3, CD20, CD4, and CD8) and T helper (Th) cytokines including interferon (IFN)-γ (Th1 type), interleukin (IL)-4 (Th2 type), IL-17 (Th17 type), and IL-10 (regulatory T cell type) by immunohistochemistry in buccal mucosa specimens from 2 GS patients compared with 15 OLP patients. (nih.gov)
  • Pineal microglia/macrophages were common and represent an important candidate for mediating these lymphocyte-pineal interactions via secretion of cytokines and chemokines. (biomedcentral.com)
  • effector memory
  • Objectives Evaluate the number and distribution of circulating CD4+ T lymphocytes and their CD4+ naïve T cells (T N ), central memory (T CM ), non-terminated effector memory (T NTEM ) and terminated effector memory (T TEM ) T cells subsets in a population of recently diagnosed DMARD naive RA patients before and along the first 6 months of methotrexate (MTX) treatment. (bmj.com)
  • bone marrow
  • 2009 Changes of lymphocyte subsets in acute leukemia patients after HLA-mismatched nonmyeloablative hematopoietic stem cell transplantation 2010 "Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: clinical report", published in Biol Blood Marrow Transplant 2009 A modified haploidentical nonmyeloablative transplantation without T cell depletion for high-risk acute leukemia: successful engraftment and mild GVHD" published in Biol Blood Marrow Transplant. (wikipedia.org)
  • cells
  • There was a significantly greater increase in the percentage of Thy1.2+ and, especially of, Lyt-2+ cells in stimulated splenic lymphocytes from untrained mice given an exhaustive exercise session compared with controls and with trained mice. (biomedsearch.com)
  • Lymphocytes strongly contribute to the pathology of multiple sclerosis (MS). Thereby, frequently activated or reactivated autoreactive lymphocytes differentiate into effector cells that enter the central nervous system (CNS) causing tissue inflammation and damage. (biomedcentral.com)
  • While fingolimod reduced the number of almost all analyzed subsets in the circulation IFN-β specifically reduced the numbers of marginal zone and memory B cells. (biomedcentral.com)
  • In conclusion, we think that by reducing "memory" type lymphocytes in the circulation fingolimod and IFN-β impair reactivation of autoreactive cells. (biomedcentral.com)
  • This assay provides absolute (cells/mcL) and relative (%) quantitation for the main categories of T cells, B cells, and NK cells, in addition to a total lymphocyte count (CD45+). (testcatalog.org)
  • The studies on diurnal (circadian) variation in lymphocyte counts have demonstrated progressive increase in CD4 T-cell count throughout the day, while CD8 T cells and CD19+ B cells increase between 8:30 a.m. and noon with no change between noon and afternoon. (testcatalog.org)
  • Image analysis of immunocytochemically stained sections showed that the majority of lymphocytes were CD3 + (80%) with the remaining 20% comprising B-cells and monocytes (Bu-1 + ), which tended to distribute along the periphery of the PALT. (biomedcentral.com)
  • Effects of the 24-h light:dark cycle on these lymphocyte-pineal interactions were suggested by an increase in the area of PALT, a decline in the density of TCRαβ/Vβ 1 + cells, and a decline in the area density of Bu-1 + microglia at the light:dark interphase (1900 h) compared to the dark:light interphase (0700 h). (biomedcentral.com)
  • The lack of B-lymphocytes in the testis is significant, since these are the antibody-producing cells of the immune system. (wikipedia.org)
  • T-lymphocytes (T-cells) are white blood cells which take part in cell-mediated immunity. (wikipedia.org)
  • If undiagnosed or left untreated, HIV usually progresses to AIDS, defined as possessing a CD4+ lymphocyte count under 200 cells/μl or HIV infection plus co-infection with an AIDS-defining opportunistic infection. (wikipedia.org)
  • Lymphocytes include natural killer cells (Phagocytes) (which function in cell-mediated, cytotoxic innate immunity), T cells (for cell-mediated, cytotoxic adaptive immunity), and B cells (for humoral, antibody-driven adaptive immunity). (wikipedia.org)
  • The three major types of lymphocyte are T cells, B cells and natural killer (NK) cells. (wikipedia.org)
  • Highly reproducible results Possible to analyze subsets of cells using physical and immunofluorescent markers. (wikipedia.org)
  • Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. (wikipedia.org)
  • However, perhaps the most important CFSE investigations have been those demonstrating that many of the effector functions of lymphocytes, such as cytokine production by T lymphocytes, and antibody class switching by B cells, are division dependent. (wikipedia.org)
  • circadian
  • The pineal gland of the chicken contains large accumulations of lymphocytes that suggest an important role related to homeostatic circadian neuro-immune interactions. (biomedcentral.com)
  • Migration
  • CFSE was originally developed as a fluorescent dye that could be used to stably label lymphocytes and track their migration within animals for many months. (wikipedia.org)
  • cell
  • Identification of T cell subsets and B lymphocytes in mouse brain experimental allergic encephalitis lesions. (jimmunol.org)
  • A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system. (wikipedia.org)
  • In normal situations, the coarse, dense nucleus of a lymphocyte is approximately the size of a red blood cell (about 7 μm in diameter). (wikipedia.org)
  • Detailed protocols are now available that can be used to label lymphocytes (and other cell types) with a high degree of reliability and precision. (wikipedia.org)
  • significant
  • There was a significant effect of stimulation by Con A on the percentage of splenic lymphocytes positive for Thy1.2, Lyt-2, L3T4, and goat anti-mouse Ig, regardless of treatment condition. (biomedsearch.com)