• Laser scanning microscopes with highly sensitive detectors and ultra-short pulsed femtosecond laser technology are available, as well as inverted microscopes for confocal long-term imaging. (uni-ulm.de)
  • The microscopes employ krypton-argon, argon, and helium-neon lasers and a Windows-based host computer running the NT operating system. (fsu.edu)
  • The Zeiss confocal website offers technical and application information, as well as a gallery of digital images acquired with these microscopes. (fsu.edu)
  • Leica Microsystems Confocal Microscopy - Leica's confocal microscopy website provides introductory material about confocal microscopy, tutorials and manuals about Leica microscopes, FAQ's, application notes, a publications listing, and an image gallery. (fsu.edu)
  • The system is available with the IX70 inverted research microscope and the AX70, BX50, BX60 and BX50WI upright research microscopes. (fsu.edu)
  • For system developers who wish to build microscopes entirely from Thorlabs' catalog of parts (see the For Developers tab for an example), we offer body attachments and extensions that provide connections to our standard mechanical interfaces, including SM1 threads (1.035"-40), SM2 threads (2.035"-40), and taps for 30 mm and 60 mm cage compatibility. (thorlabs.com)
  • Once submitted, we will try and place you in contact with a suitable Spinning Disk Confocal Microscopes supplier within 48 hours. (news-medical.net)
  • The MultiPark confocal microscope platform currently has a Leica SP8 laser scanning confocal microscopes for imaging live and fixed tissue and cells. (lu.se)
  • Scanning confocal electron microscopy (SCEM) is an electron microscopy technique analogous to scanning confocal optical microscopy (SCOM). (wikipedia.org)
  • In this technique, the studied sample is illuminated by a focussed electron beam, as in other scanning microscopy techniques, such as scanning transmission electron microscopy or scanning electron microscopy. (wikipedia.org)
  • However, practical design and construction of scanning confocal electron microscope is a complex problem first solved by Nestor J. Zaluzec. (wikipedia.org)
  • His first scanning confocal electron microscope demonstrated the 3D properties of the SCEM, but have not realized the sub-nanometer lateral spatial resolution achievable with high-energy electrons (lateral resolution of only ~80 nm has been demonstrated). (wikipedia.org)
  • As compared to conventional electron microscopy (TEM, STEM, SEM), SCEM offers 3-dimensional imaging. (wikipedia.org)
  • Confocal microscopy Confocal laser scanning microscopy Electron microscopy Scanning electron microscope Scanning transmission electron microscopy Transmission electron microscopy Zaluzec, N.J. (2003) "Scanning confocal electron microscope" U.S. Patent 6,548,810 Zaluzec, N.J. (2003). (wikipedia.org)
  • The Scanning Confocal Electron Microscope" (PDF). (wikipedia.org)
  • Scanning Transmission Electron Microscopy of Nanomaterials. (wikipedia.org)
  • Journal of Electron Microscopy. (wikipedia.org)
  • Even though resolution is somewhat enhanced with confocal microscopy over conventional widefield techniques, it is still considerably less than that of the transmission electron microscope. (olympusconfocal.com)
  • Also presented in a nicely-executed format is information about video-enhanced light microscopy, scanning probe microscopy, electron microscopy, electron diffraction, and digital imaging. (fsu.edu)
  • and low signal-to-noise ratio electron microscopy imagery. (researchgate.net)
  • The synthesis of NPF@DOX was analyzed using UV-Vis and FT-IR spectroscopy and its morphology using transmission electron microscopy (TEM). (doaj.org)
  • 3 ) used scanning and transmission electron microscopy to examine biofilms on trickling filters in a wastewater treatment plant and showed them to be composed of a variety of organisms (based on cell morphology). (cdc.gov)
  • Much of the work in the last 2 decades has relied on tools such as scanning electron microscopy (SEM) or standard microbiologic culture techniques for biofilm characterization. (cdc.gov)
  • Biodegradation is proven by a range of methods including transmission electron microscopy, UV-visible-NIR spectroscopy, Raman spectroscopy, and confocal Raman imaging. (cdc.gov)
  • Facilities for 3D optical imaging and electron microscopy at Materials Engineering with instruments including E-SEM FEI Quanta 200 MKII with analytical system Pegasus (EBSD+EDS) from EDAX and optical microscope Keyence VHX-6000. (lu.se)
  • The Fandango 515 nm solid-state laser from Cobolt AB offers up to 150 mW CW output power, making it ideal for fluorescence applications such as confocal microscopy and single molecule analysis. (laserfocusworld.com)
  • The Cobolt Fandango™, now available with up to 150 mW CW output power from the same small package, is not only perfectly suited for power demanding fluorescence analysis applications such as confocal microscopy, high-speed plate reading and single molecule analysis, but now with even higher output power, as a general all solid state alternative to bulky Ar+ gas lasers. (laserfocusworld.com)
  • There has been a tremendous explosion in the popularity of confocal microscopy in recent years, due in part to the relative ease with which extremely high-quality images can be obtained from specimens prepared for conventional fluorescence microscopy, and the growing number of applications in cell biology that rely on imaging both fixed and living cells and tissues. (olympusconfocal.com)
  • Presented in Figure 1 are a series of images that compare selected viewfields in traditional widefield and laser scanning confocal fluorescence microscopy. (olympusconfocal.com)
  • Likewise, widefield fluorescence imaging of whole rabbit muscle fibers stained with fluorescein produce blurred images (Figure 1(b)) lacking in detail, while the same specimen field (Figure 1(e)) reveals a highly striated topography in confocal microscopy. (olympusconfocal.com)
  • Optiscan - The Optiscan Personal Confocal microscope offers a twin detection system utilizing both argon-ion and krypton-argon lasers for simultaneous fluorescence imaging. (fsu.edu)
  • The MicroTime 200 time-resolved fluorescence microscope system is a powerful instrument capable of Fluorescence Lifetime Imaging (FLIM) with single molecule detection sensitivity. (picoquant.com)
  • In vivo vMSOT brain imaging of P301L mice showed higher retention of PBB5 in the tau-laden cortex and hippocampus compared to wild-type mice, as confirmed by ex vivo vMSOT, epi-fluorescence, multiphoton microscopy, and immunofluorescence staining. (springer.com)
  • Les param tres d imagerie et la distribution de l intensit originelle de l objet sont calcul s en modifiant l algorithme AM. Due la nature de la lumi re incoh rente en microscopie fluorescence, il est possible d estimer la phase partir des intensit s observ es en utilisant un mod le d optique g om trique. (inria.fr)
  • The system acquires and analyzes FCS and FCCS (Fluorescence Cross-Correlation Spectroscopy) data. (lu.se)
  • Cellomics Platform at MultiParkThe Cellomics ArrayScan VTI HCS Reader enables automated acquisition, visualization and quantification of a large number of images, with an automated fluorescence and brightfield microscopy allowing extraction of quantitative data from intensity and area measurement in high-throughput format. (lu.se)
  • The Confocal Laser Scanning Microscopy (CLSM) allows for a three-dimensional (3D) reconstruction of images of early pregnancy villous vascularization. (nih.gov)
  • Confocal laser scanning microscopy (CLSM) has rapidly become an essential tool in the life sciences laboratory, enabling high-resolution and minimally intrusive optical sectioning of fluorescent samples. (strath.ac.uk)
  • Most commercially available CLSM systems employ a gas laser, e.g. a Kr/Ar laser, to provide the excitation radiation. (strath.ac.uk)
  • An important criterion is that the particle size is large enough to admit structural analyses via confocal laser scanning microscopy (CLSM). (lu.se)
  • The Core Facility "Confocal and Multiphoton Microscopy" is a member of the Center for Translational Imaging MoMAN . (uni-ulm.de)
  • It is a facility specialised in molecular imaging that provides a unique spectrum of optical microscopy and is open to all scientists from the Faculty and University. (uni-ulm.de)
  • 3D imaging in SCEM was expected from the confocal geometry of SCEM, and it has recently been confirmed by theoretical modeling. (wikipedia.org)
  • Tony Wilson, Brad Amos, and John White nurtured the concept and later (during the late 1980s) demonstrated the utility of confocal imaging in the examination of fluorescent biological specimens. (olympusconfocal.com)
  • Andor - Andor Technology offers a range of confocal and live cell imaging systems through their Microscopy Systems Division. (fsu.edu)
  • In addition to product information, the Andor site includes in its library a section on confocal imaging that provides an excellent concise introduction to basic confocal concepts and equipment. (fsu.edu)
  • The system, which is designed to be utilized in conjunction with an existing microscope, provides automation of internal multi-position excitation and is equipped with dichroic and emission filter wheels that permit fast multi-dimensional imaging of up to five or more fluorescent probes in a single sample. (fsu.edu)
  • Confocal Imaging - Developed by the Laboratory for Optical and Computational Instrumentation at the University of Wisconsin, this website provides an introduction to confocal imaging and a variety of related topics. (fsu.edu)
  • From Bones to Atoms: Imaging Nature Across Dimensions - Written by scientists from the M.E. M ller Institute for Microscopy at the University of Basel (Switzerland), this website offers introductory information about optical sectioning using confocal microscopy techniques. (fsu.edu)
  • Despite being a widely used tool for biomedical optical imaging, confocal microscopy has limitations to its performance due to the diffraction limit of light, sample photobleaching, and limited tissue penetration. (biotium.com)
  • Additionally, the authors adapted super-resolution imaging techniques from structured illumination microscopy (SIM) to resolve the diffraction limitations of confocal microscopy. (biotium.com)
  • Their method provides an outline for future studies to implement a multiview confocal microscopy platform to improve imaging of biological tissues. (biotium.com)
  • We demonstrated non-invasive whole-brain imaging of tau in P301L mice with vMSOT system using PBB5 at a previously unachieved ~ 115 μm spatial resolution. (springer.com)
  • To determine which cells are expressing specific cellular markers and how these cells are organized relative to each other requires volumetric imaging of the pre-implantation embryos by confocal microscopy. (zeiss.com)
  • Imaging silicon atoms with terahertz-driven scanning tunnelling microscopy (TD-STM). (rhk-tech.com)
  • Our modular Cerna components make it simple to adapt this microscopy platform for a wide variety of imaging modalities and experimental applications. (thorlabs.com)
  • These qualities make the instruments particularly useful in the high speed imaging of living systems. (news-medical.net)
  • Incorporating unique and powerful functions in a reliable, high performance system, ideally suited to the research and analytical lab, the XploRA PLUS is our best multi-sample, multi-user Raman imaging microscope ever. (horiba.com)
  • The SWIFT Fast Raman images are the fastest fully confocal Raman images available, typically 10x faster than conventional Raman imaging. (horiba.com)
  • We have conducted such simulations of 3D as well as 2D systems, where the latter is also relevant, given that the clusters sometimes deposit onto the glass surfaces upon imaging. (lu.se)
  • Confocal Microscope Platform at MultiParkLeica SP8 confocal microscope for imaging of fixed tissue and cells. (lu.se)
  • Imaging of reconstituted capsid-nuclei system confirms specific capsid binding to the NPCs at the nuclear membrane. (lu.se)
  • When imaged with a laser scanning confocal microscope (Figure 1(d)), the medulla thick section reveals a significant degree of structural detail. (olympusconfocal.com)
  • Fortuitously, shortly after Minsky's patent had expired, practical laser scanning confocal microscope designs were translated into working instruments by several investigators. (olympusconfocal.com)
  • Dutch physicist G. Fred Brakenhoff developed a scanning confocal microscope in 1979, while almost simultaneously, Colin Sheppard contributed to the technique with a theory of image formation. (olympusconfocal.com)
  • Carl Zeiss - The LSM 510 laser scanning confocal microscope offered by Zeiss can collect data in up to four channels simultaneously utilizing a quad-photomultiplier 12-bit A/D detection system. (fsu.edu)
  • The Core Facility "Confocal and Multiphoton Microscopy" of the Faculty of Medicine has existed in its current size since spring 2013. (uni-ulm.de)
  • The facility provides expertise in the field of confocal and multiphoton microscopy, data analysis, evaluation and interpretation as well as the conception and implementation of experiments. (uni-ulm.de)
  • The Core Facility "Confocal and Multiphoton Microscopy" offers services and guidance for all scientific questions concerning live cell microscopy. (uni-ulm.de)
  • Continuing in this arena, Egger went on to develop the first mechanically scanned confocal laser microscope, and published the first recognizable images of cells in 1973. (olympusconfocal.com)
  • The confocal Raman instrument used in this experiment is based on an inverted optical microscope equipped with an x,y-scan stage. (rhk-tech.com)
  • The problem is that the confocal volume sensibly depends on numerous parameters of the optical set-up, refractive index mismatch of the sample solution and the objective's immersion medium, coverslide thickness variations and especially the dependence on optical saturation of the fluorescent dye, which can occur at even very low excitation powers. (picoquant.com)
  • In parallel, using spinning disk confocal fluorescent microscopy (FM), single-molecule measurements, we investigate the average ensemble kinetics of the number of viruses which ejected their DNA versus time during an infection. (lu.se)
  • Illumina: Confocal Microscopy - Molecular Dynamics, a subsidiary of GE Healthcare (formerly Amersham Bioscience), is a manufacturer of confocal microscope systems, image analysis software, volume rendering and three-dimensional modeling tools. (fsu.edu)
  • Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)
  • To this end, we use a mouse model of Alzheimer's disease with different approaches: behavioral tests, confocal microscopy, and molecular biology. (lu.se)
  • Confocal microscopy offers several advantages over conventional widefield optical microscopy, including the ability to control depth of field, elimination or reduction of background information away from the focal plane (that leads to image degradation), and the capability to collect serial optical sections from thick specimens. (olympusconfocal.com)
  • In fact, confocal technology is proving to be one of the most important advances ever achieved in optical microscopy. (olympusconfocal.com)
  • In contrast, a thin optical section of the same grain (Figure 1(f)) acquired with confocal techniques displays a dramatic difference between the particle core and the surrounding envelope. (olympusconfocal.com)
  • Cerna is a modular microscopy platform for applications ranging from routine experiments to advanced optical systems. (thorlabs.com)
  • This platform is designed for users to configure or modify their system to exact experimental requirements, and is especially useful for setups that require large-range adjustment for positioning of the sample or wide-angle access to the objective and other optical components. (thorlabs.com)
  • This process offers much faster performance than conventional optical microscopy, while requiring only minimal illumination of samples. (news-medical.net)
  • Confocal laser scanning microscopy is a powerful technique for studying biological specimens in three dimensions (3D) by optical sectioning. (inria.fr)
  • Lund University Bioimaging Center would like to invite you to an open house demonstration for our optical microscopy platform available at the LBIC on 14-15 October. (lu.se)
  • In SK-N-SH cells, carbachol induced a rapid and transient translocation of tubulin to the plasma membrane, microtubule reorganization, and a change in cell shape as demonstrated by confocal immunofluorescence microscopy. (jneurosci.org)
  • Aims To analyse age-related changes of human conjunctiva by in vivo laser scanning confocal microscopy (LSCM). (bmj.com)
  • Additionally, the drug uptake efficiency in vitro, photo-thermal properties, release performance, and anti-tumor effects of NPF@DOX were evaluated and further demonstrated in vivo.Results: Data derived from FT-IR, UV-Vis, and TEM implied successful construction of the NPF@DOX nano-drug delivery system. (doaj.org)
  • Confocal laser scanning microscopy images and in vivo experiments demonstrated the targeting effects of FAP on OSCC. (doaj.org)
  • Biodegradation of SWCNTs can also be executed in an ex vivo culture system using primary murine eosinophils stimulated to undergo degranulation. (cdc.gov)
  • Dedicated confocal laser scanning microscopy laboratory comprising Leica and Zeiss systems with separate preparation area. (warwick.ac.uk)
  • 06 June 2023, Wetzlar, Germany - Leica Microsystems, a leader in microscopy and scientific instrumentation, has launched Autonomous Microscopy powered by Aivia. (leica-microsystems.com)
  • Autonomous Microscopy powered by Aivia brings the power of Artificial Intelligence to everyday experimental environments in an easy-to-use way," says James O'Brien, Vice President of Life Sciences and Applied Microscopy at Leica Microsystems. (leica-microsystems.com)
  • The microscope is inverted and include a motorized stage and two detectors (a standard PMT detector and a Leica hybrid detector), allowing for two-channel confocal scanning with spectral detection. (lu.se)
  • This inverted confocal microscope includes a motorized stage and a two channel confocal scanning head with spectral detection. (lu.se)
  • First trimester human villous vascularization is mainly studied by conventional two-dimensional (2D) microscopy. (nih.gov)
  • In this study, we constructed a nano-drug delivery system (NPF@DOX) targeting FAP to increase the therapeutic efficiency of synergistic chemo-photothermal therapy against OSCC.Methods: We utilized PEGylated nano-graphene oxide (NGO) to link doxorubicin (DOX) and fluorescently-labeled, FAP-targeted peptide chains via hydrogen bonding and π-π bonding to enhance the targeting capability of NPF@DOX. (doaj.org)
  • In addition, confocal microscopy on fluorescently labeled lipids verified the formation of a lipid bilayer on the nanowire surface. (lu.se)
  • The projects feature state-of-the-art methods for the investigation of cell biology, such as flow cytometry and confocal microscopy, protein interaction analyses using the proximity-ligation assay and Biacore, and genetic manipulation employing the Cas9/CRISPR system. (lu.se)
  • When ZEISS Lattice Lightsheet 7 was presented to the research community in 2020, it marked a milestone in the development of microscopy techniques for the study of life. (zeiss.com)
  • Zeiss AxioImager.Z2 and AxioObserver.Z1 instruments, Hamamatsu sCMOS and EM CCD cameras, and CellASIC ONIX microfluidic cell perfusion system. (lu.se)
  • Used for high temporal and spatial resolution complementary characterisation of microscale electrochemical systems, biological and membrane processes. (warwick.ac.uk)
  • The basic key to the confocal approach is the use of spatial filtering techniques to eliminate out-of-focus light or glare in specimens whose thickness exceeds the immediate plane of focus. (olympusconfocal.com)
  • It is fully confocal, not compromising image quality, spatial or depth resolution. (horiba.com)
  • nanoGPS Suite solution allows a colocalized combination of a variety of microscopy techniques, providing a full characterization of nanostructured materials and a precise superimposition of the results obtained. (horiba.com)
  • To help resolve this gap, four sets of ionic microgels with varying crosslinker density were synthesised and characterised using light scattering techniques and confocal microscopy. (lu.se)
  • The goal is to bring together leading experts in the field of flows of soft materials, with a particular focus on neutrons and X-rays, but also complementary techniques including NMR, confocal microscopy, theory and computer modeling. (lu.se)
  • We start this review by describing three techniques that can be used for this purpose: (i) affinity-tagged proteins (ii) the two-hybrid system and (iii) some quantitative proteomic techniques that can be used in combination with, e.g., affinity chromatography and coimmunoprecipitation for screening of protein-protein interactions. (lu.se)
  • Une approche de minimisation altern e (AM), restaure les fr quences manquantes au-del de la limite de diffraction, en utilisant une r gularisation par la variation totale sur l objet, et une contrainte de forme sur la PSF. (inria.fr)
  • Discriminating salient moving objects against complex, cluttered backgrounds, with occlusions and challenging environmental conditions like weather and illumination, is essential for stateful scene perception in autonomous systems. (researchgate.net)
  • Autonomous Microscopy powered by Aivia enables scientists to discover more by extracting the most relevant data from their experiments. (leica-microsystems.com)
  • With Autonomous Microscopy powered by Aivia, operator interaction is limited to the initial setup. (leica-microsystems.com)
  • For more information about Autonomous Microscopy powered by Aivia that is immediately available for STELLARIS users, see how AI Microscopy Enables the Efficient Detection of Rare Events . (leica-microsystems.com)
  • The system have 3 LED lasers with these laser lines: 405, 488, 514, 552 and 638 nm and two detectors of which one is a standard detector and one is a HyD SP detector. (lu.se)
  • Hot and cold wall, and chemical vapour deposition systems are located here for the growth of single walled carbon nanotubes and graphene. (warwick.ac.uk)
  • A kind of graphene foam chemical sensor (GFCS) system based on the principal component analysis (PCA) and backpropagation neural network (BPNN) was presented in this paper. (hindawi.com)
  • The GFCS system consisted of an unmodified graphene foam chemical sensor, an electrical resistance time domain detection system (ERTDS), and a pattern recognition module. (hindawi.com)
  • In the previous work [ 27 ], our group had designed an unmodified graphene foam chemical sensor system based support vector machine (SVM) for making discrimination of different chemical molecules. (hindawi.com)
  • Thus, to further reduce the complexity of data and improve the efficiency of data processing, the principal component analysis (PCA) [ 28 , 29 ] and the backpropagation neural network (BPNN) [ 30 - 32 ] were used for the graphene foam chemical sensor system (GFCS) in this paper. (hindawi.com)
  • When the organic molecules of target were introduced to the surface of graphene foam, the resistance measurement system immediately started to record the situation of fluctuant resistance of graphene foam in real time. (hindawi.com)
  • The study of these biomembranes require novel model systems and new methods. (lu.se)
  • The topography and near-field images were obtained with shear-force microscopy using a chemically etched gold tip attached to a quartz tuning fork. (rhk-tech.com)
  • Super-Resolution Structured Illumination Microscopy (SR-SIM) provides resolutions down to 120 nm, allowing visualization of individual herpesvirus capsids (HSV-1) attached to the nucleus (HSV-1 C-capsid diameter is 125 nm). (lu.se)
  • The present review will examine evidence revealing that astrocytes respond to dopamine and modulate information processing in the primary brain regions implicated in the mesolimbic dopamine system. (nature.com)
  • The review provides insight into the active role of astrocytes in dopaminergic signaling to both respond to dopamine with increases in calcium and modulate synaptic transmission (Fig. 1 ) and proposes the targeting of astrocytes for novel treatments of disease processes involving the mesolimbic dopamine system. (nature.com)
  • Using confocal microscopy, the researchers saw astrocytes engulfing axon terminals and synapses on these retinal cells. (alzforum.org)
  • Unlike wild-type cells, astrocytes in the MEGF10- and MERTK-deficient mice ingested no synaptic components and the visual system of these animals failed to mature, suggesting that phagocytosis of synapses contributes to development of the retina. (alzforum.org)
  • A non-comprenhsive list of resources for microscopy at Lund University. (lu.se)
  • Nikon Confocal Microscopy - Nikon's PCM 2000 biosciences confocal microscope employs twin photomultiplier tubes with options for single or triple configurations. (fsu.edu)
  • Capable of two-color STED microscopy with lateral resolution ~50nm with excitation wavelengths 561nm and 640nm. (lu.se)
  • During the late 1970s and the 1980s, advances in computer and laser technology, coupled to new algorithms for digital manipulation of images, led to a growing interest in confocal microscopy. (olympusconfocal.com)
  • The microscope is controlled by the Optiscan Confocal Control software and images can be analyzed with Optiscan Analyze, a Windows-based program. (fsu.edu)
  • Scanning tunneling microscopy images of Aβ1−16-Cu2+ (a,b) and Aβ1−16 (c,d). (rhk-tech.com)
  • Four strategies for validation of protein-protein interactions are presented: confocal microscopy for intracellular colocalization of proteins, coimmunoprecipitation, surface plasmon resonance (SPR) and spectroscopic studies. (lu.se)
  • Instruction in the HTS confocal microscope for long-term live cell observations. (uni-ulm.de)
  • The dorsal root ganglia (DRG) sensory neurone system has a central as well as a peripheral axonal branch departing from a single cell body. (nature.com)
  • This project was focussed on the role and timing of programmed cell death (PCD) in tracheary elements (TEs) formation during the trans-differentiation of mesophyll cells in a model system of Zinnia elegans cell culture. (europa.eu)
  • For achieving the goals we have used a model system of cell culture isolated from zinnia leaf mesophyll cells. (europa.eu)
  • Zinnia cell culture is a unique model system, which at the administration of certain ratio of cytokinins and auxins can be induced to trans-differentiate into vessel elements. (europa.eu)
  • In order to overcome these limitations, this study explored the possibility to use cancer cell derived extracellular vesicles (EVs) as drug delivery system for oncolytic adenovirus. (helsinki.fi)
  • Two major thrusts in the last decade have dramatically impacted our understanding of biofilms: the utilization of the confocal laser scanning microscope to characterize biofilm ultrastructure, and an investigation of the genes involved in cell adhesion and biofilm formation. (cdc.gov)
  • Ident- cult to deduce interaction rules from observations of the ified transcription factors for specific cell fates are, for entire system. (lu.se)
  • Additional avenues to sources of information on confocal principles, theory, and optics are also provided. (fsu.edu)
  • Researchers can now establish confocal microscopy workflows that address advanced experiments and biological questions that would be impossible or very laborious without automated procedures. (leica-microsystems.com)
  • Following Minsky's work, M. David Egger and Mojmir Petran fabricated a multiple-beam confocal microscope in the late 1960s that utilized a spinning (Nipkow) disk for examining unstained brain sections and ganglion cells. (olympusconfocal.com)
  • At this young age, retinal ganglion cells shed synapses as a normal part of visual system development. (alzforum.org)
  • Even though the idea of an immune system actively searching for and disposing of potential mutated tumor cells is over a century old, only recent developments in various fields such as mass spectrometry, immuno-checkpoint blockade strategies and in silico modelling have enabled the realization of the full potential of recruiting immune system to fight cancer and the possibilities of personalized therapies. (helsinki.fi)
  • Curvature in lipid-based biomembranes provides compartmentalization in cells and can act as regulator of biological activity in living systems. (lu.se)
  • First, the authors developed a multiview confocal microscopy platform with three objectives integrated using compact multi-electromechanical systems (MEMS)-based scanners. (biotium.com)
  • Building on established community resources, duckweed is reemerging as a platform to study plant processes at the systems level and to translate knowledge gained for field deployment to address some of society's pressing needs. (osti.gov)
  • Olympus America - The Olympus FluoView is a point-scanning, point-detection, confocal laser scanning microscope for biology research applications. (fsu.edu)
  • developed a multi-pronged approach to address the limitations of confocal microscopy and demonstrated the new capabilities on over 20 distinct fixed and live samples. (biotium.com)
  • Then, to test the limits of this system, they combined this triple-view method with line-scanning confocal microscopy and deconvolution to visualize the nuclei of an entire fixed Caenorhabditis elegans nematode labeled with NucSpot® Live 488 . (biotium.com)
  • To examine the changes in gene expression during this transition, both live and fixed samples are imaged at different timepoints using spinning disk confocal microscopy. (zeiss.com)
  • Xylem vascular system serves the plant to establish soil-plant-atmosphere continuum for water transport and supports the mechanical strength of the stems. (europa.eu)
  • The human immune system can provide a powerful tool in developing therapies against various cancers. (helsinki.fi)
  • OspC is a helical-rich homodimer that interacts with tick salivary proteins, as well as components of the mammalian immune system. (cdc.gov)
  • Unlocking the Mysteries of the Immune System: new Roles of complement proteins in Diabetes and Cancer. (lu.se)
  • Our group is dedicated to studying the role of the immune system in infections, diabetes, and cancer. (lu.se)
  • Stress may increase the risk of developing psychiatric and somatic illnesses and seems to affect the immune system. (lu.se)
  • not unique for the embryonic system but are shared by other ogenesis regulation must consider different scales of multi-cellular modeling areas. (lu.se)
  • The gross anatomy (peripheral and central nervous system) of taste, microscopic and ultrastructural morphology of taste buds, physiology of taste (modalities, distribution of taste sensations, electrophysiology of the receptors, mechanism and intensity of stimulation, and taste contrasts), as well as a few clinical applications, are discussed in this article. (medscape.com)
  • From the technical point of view, automated inspection of holes and feedback to the drilling station allows the system to directly alter the drilling parameters on-the-fly, and keep final flow within the desired range. (sbir.gov)