Systemic organ sparing treatments. Medical search. Frequent questions

Systemic lupus erythematosus (SLE) is a rheumatic disease characterized by autoantibodies directed against self-antigens, immune complex formation, and immune dysregulation, resulting in damage to essentially any organ. (medscape.com)
It has also been increasingly used as an effective steroid sparing treatment in autoimmune diseases including systemic lupus erythematosis, and vasculitis. (albertarheumatology.com)
Treatment of systemic lupus erythematosus (SLE) should be provided in cooperation with a consulting rheumatologist. (medscape.com)
Clinical studies supporting this approach were generally performed in lupus nephritis because of its frequency, severity, and quantifiable improvement or deterioration, but the same treatment approaches are generally applied to other organ systems, including the central and peripheral nervous systems and muscular disease. (medscape.com)
With little evidence base to the therapeutic modalities, a logical approach to the treatment of cerebral lupus is to build a treatment strategy around the various possible pathogeneses: (1) ischemia due to thromboses secondary to the antiphospholipid syndrome, (2) small-vessel noninflammatory proliferative vasculopathy due to cell-mediated immune mechanisms, and (3) antibody-mediated damage to spinal cord and optic nerve-akin to Devic disease. (medscape.com)
The standard treatment for the nonthrombotic syndromes associated with systemic lupus erythematosus (SLE) is immunosuppression, first with corticosteroids and with early recourse to cyclophosphamide. (medscape.com)
The discovery that Toll-like receptor signaling and interferon-alpha abundance are central elements of the systemic lupus erythematosus (SLE) disease process has led to a new appreciation for hydroxychloroquine as an essential baseline medication. (medscape.com)
Overview of Systemic Lupus. (merckmanuals.com)
Systemic lupus erythematosus is a chronic, multisystem, inflammatory disorder of autoimmune etiology, occurring predominantly in young women. (merckmanuals.com)
Systemic lupus erythematosus (SLE) is more common and severe among Black and Asian patients than among White patients. (merckmanuals.com)
Objectives Despite advances in systemic lupus erythematosus (SLE) treatment, many patients suffer from the disease and side effects. (bmj.com)

Recently, an original study, combining the analysis of more than 100 items used to describe patients' characteristics in a large sample of vasculitides with a computer simulation technique designed to test the potential diagnostic utility of the various criteria, proposed a set of eight positively or negatively discriminating items to be used as a screening tool for diagnosis in patients suspected of systemic vasculitis. (wikipedia.org)
Early diagnosis and careful treatment tailored to individual patient symptoms have improved the prognosis in what was once perceived as an often-fatal disease. (medscape.com)
You get access to the latest in diagnosis, treatment and prevention of cancer. (iuhealth.org)
Your multidisciplinary cancer care team will work with you to design an individualized cancer care plan, from diagnosis to post-treatment support. (swedish.org)
[ 7 ] Responses to corticosteroids are not durable and thus only delay definitive diagnosis and treatment. (medscape.com)
This report updates the 2006 CDC recommendations on the diagnosis and management of tickborne rickettsial diseases in the United States and includes information on the practical aspects of epidemiology, clinical assessment, treatment, laboratory diagnosis, and prevention of tickborne rickettsial diseases. (cdc.gov)
A diagnosis of breast cancer at a young age, defined per guidelines as ≤ 40 years, represents a challenging situation requiring additional attention by the treating physicians including radiation oncologists and surgeons involved in the local treatment of these tumors. (tau.ac.il)

As shown by TransCode's scientific founders, our RNA therapy invariably spares healthy organs and have essentially no systemic toxicity compared to chemotherapy. (transcodetherapeutics.com)
In particular, drug delivery is impaired by the blood-brain barrier, and cerebral toxicity limits the use of treatment modalities. (medscape.com)
Current treatments include FDA-approved systemic glucocorticoids and off-label use of glucocorticoid-sparing immunosuppressive or immunomodulating agents, but there is significant unmet need for new treatments to achieve disease control because of limited efficacy or toxicity of immunosuppressive agents or refractory disease. (globalgenes.org)
Often associated with severe and rapidly fatal systemic toxicity, if not promptly recognized and treated [ 3 ]. (scholars.direct)
To overcome this obstacle, conditional oncolytic viruses (such as conditional replication adenovirus (CRAD)) are developed to specifically target prostate without (or with minimal) systemic toxicity due to viral self-replication. (hindawi.com)
In the absence of confirmed organ dysfunction, unacceptable treatment-related toxicity, or withdrawal of consent, patients may receive NEOD001 for. (holyexperiment.org)

Precision genomics - This is an option for end or late-stage cancer that looks at the genetic structure of the tumor as well as your overall DNA to find the very best treatments for you. (iuhealth.org)
We also offer 3-D conformal radiotherapy, which delivers higher doses of radiation directly to a tumor while sparing surrounding healthy tissue. (iuhealth.org)
It occurs when cancer cells break away from the primary tumor, travel through the bloodstream or lymphatic system, and establish new tumors in different organs or tissues. (transcodetherapeutics.com)
This radically novel and highly promising therapeutic strategy against cancer relies on specific eradication of metastatic tumor cells- cells that have acquired the ability to escape into the circulation, survive during transit, and colonize a distant vital organ, such as the lungs and brain. (transcodetherapeutics.com)
The nanoparticles target tumor cells, the investigators explain, thus sparing normal tissue and avoiding the systemic side effects often associated with chemotherapy drugs. (nanowerk.com)
By heating or freezing the tumor, it treats only the cancer, sparing the kidney and surrounding normal tissue. (rogelcancercenter.org)
Second, the absence of circulation to the fibroids prevents tumor exposure to the systemic hormones and growth stimuli, such as estrogen. (sls.org)
The treatment of non-muscle-invasive bladder cancer (Ta, T1, carcinoma in situ [CIS]) begins with transurethral resection of bladder tumor (TURBT). (medscape.com)

Polyarteritis nodosa (PAN) is a systemic necrotizing inflammation of blood vessels (vasculitis) affecting medium-sized muscular arteries, typically involving the arteries of the kidneys and other internal organs but generally sparing the lungs' circulation. (wikipedia.org)
However, the lungs are usually spared. (msdmanuals.com)
We believe direct delivery of the therapeutic to the site of infection with locally higher concentrations in the infected areas of the lungs can help increase efficacy while mitigating systemic side effects. (infectioncontroltoday.com)
Sarcoidosis is a systemic inflammatory disease characterized by the formation of noncaseating granulomas in affected organs, most commonly the lungs, lymph nodes, skin, and eyes. (aao.org)
Newer research indicates that other graft-versus-host disease target organs include the immune system (the hematopoietic system , e.g., the bone marrow and the thymus ) itself, and the lungs in the form of immune-mediated pneumonitis . (wikipedia.org)
Fluconazole injection is used to treat fungal infections, including yeast infections of the mouth, throat, esophagus (tube leading from the mouth to the stomach), abdomen (area between the chest and waist), lungs, blood, and other organs. (tajgenerics.com)
Dr Penkert and colleagues note that nocardia infects the lungs and spreads from there, with potential damage to the central nervous system when intraepithelial and systemic cellular immunity fails. (medscape.com)

Once in the bloodstream or lymphatic system, cancer cells can travel to distant organs or tissues, where they can lodge and form secondary tumors. (transcodetherapeutics.com)
To avoid damaging healthy organs, it is crucial that the therapeutic activity of microbes be targeted to tumors. (nature.com)
Most of these tumors are locally confined, and complete but conservative surgical excision is the treatment of choice. (merckvetmanual.com)
Treatment for these tumors targets local control using localized techniques described above. (merckvetmanual.com)
When tumors are multiple or when surgical excision is not feasible, radiation therapy appears to be the best secondary treatment. (merckvetmanual.com)
For tumors resistant to radiation and for those animals unable to receive radiation therapy, systemic treatment with administration of chemotherapeutic agents, including melphalan, chlorambucil, cyclophosphamide, and glucocorticoids, have been recommended and have yielded long-term survival. (merckvetmanual.com)
These range from large coils and flow occluders for larger vessels to liquid agents and particles microns in diameter for the treatment of vascular malformations and tumors. (sls.org)
These macrophages release exosomes loaded with Paclitaxel (PTX), a chemotherapeutic agent that is used in the treatment of breast, ovarian, lung, bladder, prostate, melanoma, esophageal, as well as other types of solid tumors. (acsh.org)

Polyarteritis nodosa is a systemic necrotizing vasculitis that typically affects medium-sized muscular arteries and occasionally affects small muscular arteries, resulting in secondary tissue ischemia. (msdmanuals.com)
Intimal proliferation with secondary thrombosis and occlusion leads to organ and tissue infarction. (msdmanuals.com)
The goal of surgery is curative, and our treatment planning seeks to spare as much noncancerous tissue as possible. (rogelcancercenter.org)
Blood chemistry studies can reveal substances that indicate cancer in a particular organ or tissue. (healthline.com)
In contrast to organ/tissue transplant associated GvHD, the incidence of TA-GvHD is increased with HLA matching (first-degree or close relatives). (wikipedia.org)
[6] Chronic graft-versus-host disease also attacks the above organs, but over its long-term course can also cause damage to the connective tissue and exocrine glands . (wikipedia.org)
It is characterized by wide spread facial necrosis, involving superficial, deep fascia's and subcutaneous adipose tissue with relative sparing of skin and underlying musculature. (scholars.direct)
If it remains undiagnosed, it could develop into a extra superior kind with numerous tissue and organ problems, oral manifestations and issues (Straka, 2011) erectile dysfunction treatment ottawa [url=https://cemalta.gov.mt/wp-content/docs/purchase-cheap-malegra-dxt-plus/]buy 160 mg malegra dxt plus otc[/url]. (ehd.org)

Advances in treatment using targeted biological therapies may further improve treatment outcomes. (medscape.com)
The European League Against Rheumatism ( EULAR ) has published recommendations for the management of patients with Sjögren's syndrome (SjS) with topical and systemic therapies. (dentistrytoday.com)
Systemic therapies may be considered for the treatment of active systemic disease. (dentistrytoday.com)
B-cell targeted therapies may be considered in patients with severe, refractory systemic disease. (dentistrytoday.com)
Systemic therapies are medications or interventions that address cancer throughout the body. (iuhealth.org)
Local therapies target a specific body part or organ. (iuhealth.org)
Current treatments of metastatic disease usually involve a combination of therapies, including chemotherapy, radiation therapy, targeted therapies, immunotherapy, and surgery when feasible. (transcodetherapeutics.com)
Systemic therapies travel through the bloodstream and affect cells in other body parts. (swedish.org)
All subjects, including the control group, received standard background treatments, with 89 percent of dosed subjects receiving one or more immunosuppressive or immunomodulating therapies. (globalgenes.org)
In addition, future perspectives including the ongoing trials and the potential impact of combined approaches with systemic therapies (such as immunotherapy) are reviewed. (tau.ac.il)
Current therapies offered to patients with symptomatic fibroids include medical and surgical treatments. (sls.org)

The most important tool in the care of the patient with SLE is careful and frequent clinical and laboratory evaluation to tailor the medical regimen and to provide prompt recognition and treatment of disease flares. (medscape.com)
The therapeutic management of SjS has not changed substantially in recent decades, EULAR says, as treatment decisions remain challenging in clinical practice without a specific therapeutic target beyond relief of symptoms as the most important goal. (dentistrytoday.com)
Clinical trials - There may also be the opportunity for you to participate in clinical trials, often giving you access to new treatment options that might not otherwise be available. (iuhealth.org)
Now, investigators from the University of North Carolina report what they believe is the first pre-clinical demonstration of the potential of molecularly targeted nanoparticles as a promising new class of agents that can improve chemoradiotherapy treatment. (nanowerk.com)
Therefore, there remains a great clinical need for additional therapeutic modalities to further improve treatment for patients with devastating injuries that lead to symptomatic neuromas. (bvsalud.org)
In the ensuing 25 years, the epidemiology, virology, pathophysiology, clinical course, and treatment of hantavirus pulmonary syndrome have been the focus of ongoing research. (cdc.gov)
We believe we see clinical activity of lenabasum 20 mg administered twice daily compared to the control group just receiving standard background treatments, with higher TIS scores in classic dermatomyositis subjects with muscle weakness and skin involvement and greater reduction in CDASI activity score in subjects with active skin disease but normal muscle strength. (globalgenes.org)
The purpose of information collection was to clarify the main problems, including the clinical manifestations and/or any obstacles that the patients encountered during the treatment. (inhibitorkit.com)
Clinical presentation of sarcoidosis depends on the severity and organ involved. (aao.org)
As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
Coauthor of an accompanying editorial , Reinhard Hohlfeld, MD, Institute of Clinical Neuroimmunology, Klinikum der LMU München, Germany, told Medscape Medical News that this appears to be the first report of nocardiosis with alemtuzumab in a patient who was not considered to be immunocompromised before treatment. (medscape.com)
11. Any clinical condition requiring systemic immunosuppression therapy other than stable maintenance therapy for at least 3 months prior to Visit 1. (who.int)

Treatment with corticosteroids and immunosuppressants is often effective. (msdmanuals.com)
Corticosteroids are used in low-dose oral, high-dose oral, or high-dose intravenous (IV) regimens according to the severity of potential organ damage. (medscape.com)
Treatment of severe, ongoing, active disease requires corticosteroids and immunosuppressants. (merckmanuals.com)
First line treatment is usually with corticosteroids, often prednisolone 20 to 40 mg/day (initial dosage, followed by gradual reduction) if topical administration is not possible, although it is not universally accepted that steroids change the course of the disease. (enetmd.com)
Phototherapy eliminates the need of using corticosteroids ointments or other systemic medications that can have a negative effect on the body. (bibalex.org)
Atectura Breezhaler is indicated as a maintenance treatment of asthma in adults and adolescents 12 years of age and older not adequately controlled with inhaled corticosteroids and inhaled short-acting beta 2 -agonists. (medicines.org.uk)

Note that the fixed erythema, sometimes with mild induration as seen here, characteristically spares the nasolabial folds. (medscape.com)
Skin lesions include malar butterfly erythema (flat or raised) that generally spares the nasolabial folds. (merckmanuals.com)

See Treatment and Medications . (medscape.com)
With this in mind, EULAR supported an international task force to develop evidence-based and consensus-based recommendations for the management of SjS patients with topical and systemic medications. (dentistrytoday.com)
Subjects with essential hypertension controlled on 1 or 2 antihypertensive medications or uncontrolled on 0-2 antihypertensive medications will be included in the RADIANCE Solo cohort while subjects with treatment-resistant hypertension on a minimum of 3 antihypertensive medications will be included in the RADIANCE Trio cohort. (qmul.ac.uk)
Risk factors for infections of the spine involve conditions that weaken the patient's immune system, such conditions include diabetes mellitus, use of immunosuppressant medications, cancer, HIV/AIDS, malnutrition, history of an organ transplant and intravenous drug abuse. (wheelessonline.com)

Improve the systemic lymphatic system and the organization of loose skin. (slimmingequipmentbody.com)

For children with renal disease, recognition of the steroid-sparing effect of immunosuppressive agents, such as azathioprine, mycophenolate, and cyclophosphamide, has greatly improved kidney organ survival and outcome. (medscape.com)
Synthetic immunosuppressive agents should mainly be used as GC-sparing agents, with no evidence supporting the choice of one agent over another. (dentistrytoday.com)
The systemic organ-specific therapeutic approach may, as a general rule, follow the sequential (or combined) use of GCs, immunosuppressive agents, and biologics. (dentistrytoday.com)

It is believed that a mean arterial blood pressure of 70 mm Hg is required for adequate perfusion of vital organs such as the brain, heart and kidneys. (vin.com)

Blood pressure is directly affected by cardiac output and systemic vascular resistance (BP = CO x SVR). (vin.com)
Therefore, hypotension is normally a result of a combination of factors such as bradycardia, vasodilation (decreases in systemic vascular resistance), and decreases in cardiac contractility which in turn will reduce stroke volume and cardiac output. (vin.com)
The left ventricle (LV) must generate a relatively high-pressure gradient to overcome the high systemic vascular resistance (SVR), whereas the RV needs to generate a lower pressure gradient to overcome the lower pulmonary vascular resistance (PVR). (medscape.com)

Overview of Vasculitis Vasculitis is inflammation of blood vessels, often with ischemia, necrosis, and organ inflammation. (msdmanuals.com)
may develop a systemic vasculitis similar to PAN (sometimes called secondary PAN). (msdmanuals.com)

Rheumatoid Arthritis (RA) Rheumatoid arthritis is a chronic systemic autoimmune disease that primarily involves the joints. (msdmanuals.com)

PAN may affect nearly every organ system and thus can present with a broad array of signs and symptoms. (wikipedia.org)
These recommendations form a logical sequence starting with the management of the central triplet of symptoms-dryness, fatigue, and pain-followed by the management of systemic disease. (dentistrytoday.com)
Patients typically present with systemic symptoms (eg, fever, fatigue). (msdmanuals.com)
However, in some cases, metastatic cancer may be incurable, and treatment focuses on palliative care to manage symptoms and enhance comfort. (transcodetherapeutics.com)
Nevertheless, no single treatment option has been successful in completely resolving the associated constellation of symptoms. (bvsalud.org)
The signs and symptoms of dermatomyositis reflect multi-organ involvement, which includes distinctive skin rashes usually accompanied by proximal muscle weakness, and can also include pulmonary, cardiac, gastrointestinal, and joint involvement. (globalgenes.org)
Her entire course of treatment has been uneventful & currently, she is free of her symptoms. (oncolifehospitals.com)
However, because of the risk of osteoporosis and development of symptoms of menopause, treatment is recommended only for a short time, and following discontinuation, the symptoms may recur. (sls.org)
Key issues are to determine (1) whether the patient requires treatment, this usually being based on symptoms, and then (2) the extent of symptomatic disease, and (3) whether this is acute or chronic. (enetmd.com)
Tadalafil tablets are indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH). (nih.gov)

The ReCor Medical Paradise® Renal Denervation System (Paradise System) is a catheter-based system that delivers ultrasound energy to thermally ablate and disrupt the renal efferent and afferent sympathetic nerves while sparing the renal arterial wall. (qmul.ac.uk)

Osler was the first physician who recognized that systemic features of the disease could occur without skin involvement. (medscape.com)
Treatment of systemic disease should be tailored to organ-specific severity using the EULAR SjS disease activity index ESSDAI definitions. (dentistrytoday.com)
Glucocorticoids (GCs) should be used at the minimum dose and length of time necessary to control active systemic disease. (dentistrytoday.com)
Treatment of B-cell lymphoma should be individualized according to the specific histological subtype and disease stage. (dentistrytoday.com)
[ 2 ] may have systemic disease. (medscape.com)
Sarcoid is a systemic inflammatory disease and can manifest itself in multiple ways. (aao.org)
Graft-versus-host disease ( GvHD ) is a syndrome , characterized by inflammation in different organs. (wikipedia.org)
Cutaneous lymphosarcoma may occur as a disease in which the skin is the initial and primary site of involvement, or it may be secondary to systemic, internal disease. (merckvetmanual.com)
Most people recover fully within two years, with or without treatment, but some develop a persistent, chronic form of the disease. (enetmd.com)
Sarcoidosis is a disease of unknown cause that is characterized by the presence of noncaseating granulomas in at least two organs. (enetmd.com)

The Immunoscore and circulating tumour DNA (ctDNA) are studied to evaluate which patients should receive no, 3, or 6 months of adjuvant treatment. (rug.nl)
Two ongoing RCTs study immune checkpoint inhibitors (ICI) in patients with microsatellite instable high (MSI-H) early colon cancer as adjuvant treatment. (rug.nl)
The complete response rate in patients with MSI-H tumours following ICI in neoadjuvant trials has potential organ-sparing implications. (rug.nl)
In patients with cardiac sarcoidosis, giant cell myocarditis or eosinophilic myocarditis the use of immunosuppressive treatment is recommended, as is the case in myocarditis associated with autoimmune disorders. (intechopen.com)
No two patients, or their treatment plans, are alike. (swedish.org)
All Swedish sarcoma patients benefit from leading-edge imaging and diagnostic techniques, state-of-the-art treatment options and our wide selection of high-quality support services. (swedish.org)
The treatment of recurrent osteosarcoma is primarily surgical in the case of isolated lung metastases, although stereotactic RT, radiofrequency ablation, or cryotherapy might be alternative options in patients unfit for surgery. (medscape.com)
Treatment of patients with extraskeletal ES follows the same principles as treatment for bone ES and incorporates chemotherapy in all cases, as well as postoperative RT in most cases. (medscape.com)
Finally, organs-at-risk sparing systems as strategy for prevention of radiation-related long-term toxicities should be strongly considered for these patients. (tau.ac.il)
Management-there is no single treatment for all patients with sarcoidosis. (enetmd.com)
The cryptic light chain epitope is thought to be exposed during misfolding and aggregation but is not available in light chains native conformation or in fully formed immunoglobulin.9 Accordingly, 2A4 was shown to immunoreact with BMS303141 both soluble and insoluble light chain aggregates derived from samples from patients with AL while sparing normally folded light chain. (holyexperiment.org)
In vivo, 2A4 promoted AL amyloid clearance in a mouse amyloidoma model by engaging phagocytes.9 Therefore, NEOD001 is hypothesized to directly target and clear light chain amyloid deposited in affected organs of patients with AL, with the potential to restore organ function. (holyexperiment.org)
We report interim results from the dose-escalation component of an ongoing, first-in-human, phase I/II dose-escalation/expansion study of NEOD001 in patients with AL amyloidosis and persistent organ dysfunction. (holyexperiment.org)
They point out that previous cases of pulmonary and disseminated nocardiosis have been associated with alemtuzumab treatment, but only in patients with preexisting conditions that compromise immunity, including non- Hodgkin's lymphoma, B cell lymphocytic leukemia, and organ transplantation. (medscape.com)
That matters because we may eventually be able to treat patients with smaller and more accurate doses of powerful chemotherapy drugs resulting in more effective treatment with fewer and milder side effects. (acsh.org)
[ 1 , 2 ] Greater knowledge of the pathophysiology of PH and advances in its treatment have led to improvements in both functional status and life expectancy for these patients. (medscape.com)

The functional capacity of the vital organs is entirely dependent on the presence of sufficient perfusion and oxygenation. (medscape.com)

In severe cases, treatment with mechanical circulatory support and/or heart transplantation may be required. (intechopen.com)
One of its key applications is in the treatment of invasive candidiasis, a severe condition caused by Candida species entering the bloodstream. (tajgenerics.com)

In addition, the ability to deliver the dose of an antimicrobial agent conveniently and with true portability in a handheld nebulizer for multiple dose administrations could lead to significant treatment improvements, specifically related to infection caused by B anthracis . (infectioncontroltoday.com)
Brachytherapy would help with better conformality, making it feasible to deliver maximum dose to the tumour sparing the surrounding normal structures (OARs) like bladder, rectum and sigmoid. (oncolifehospitals.com)
With the availability of State-of-the-Art Advanced Radiation technology, it was feasible to deliver standard treatment of care using combination of EBRT & Brachytherapy thus enabling maximum tumour dose while sparing surrounding healthy organs (minimal side effects) reflecting into better quality life. (oncolifehospitals.com)

QN-05 is targeted for the treatment of pneumonia, while QN-06 is intended for pulmonary infections resulting from exposure to the biodefense agent Bacillus anthracis , the causative agent of anthrax. (infectioncontroltoday.com)

If left untreated, the tip result is systemic infection that commonly leads to blindness, insanity, and eventual demise. (ehd.org)

Sjögren Syndrome Sjögren syndrome is a relatively common chronic, autoimmune, systemic, inflammatory disorder of unknown cause. (msdmanuals.com)
Seropositive findings for neuromyelitis optica (NMO)-immunoglobulin G (IgG) antibody occurring with SS/SLE (Sjogren syndrome/SLE overlap) or non-organ-specific antibodies favors coexisting NMO (Devin syndrome) rather than a vasculitic process. (medscape.com)
NB Cases of PIMS-TS - a novel post infectious systemic hyperinflammatory syndrome - have been reported in children in Victoria. (rch.org.au)

Alternatively, a bladder-sparing approach of TURBT followed by concurrent radiation therapy and systemic chemotherapy (trimodality therapy) may be used. (medscape.com)

When surgery alone isn't curative, there are systemic treatments that can hold the kidney cancer at bay for years. (rogelcancercenter.org)

Manifestations referable to any organ system may appear. (merckmanuals.com)

In most of cases, the patient evolves with systemic inflammatory response and organ dysfunction if resuscitative measures and aggressive surgical debridement could not be expedited. (scholars.direct)
The report call attention to the successfully management of this condition, with appropriate surgical intervention, intensive support and antimicrobial treatment. (scholars.direct)

Pancreatic fat is associated with systemic vascular complications and is associated with subclinical atherosclerosis ( 6 ). (fitnesshacks.org)
Cerebral nocardiosis should be added to the list of differential diagnoses when neurologic complications arise during alemtuzumab treatment," the editorialists conclude. (medscape.com)
EASD Post-Graduate Course on the Current Treatment of Diabetes and its Complications. (endocrineglandsurgery.net)
Once cirrhosis develops, treatment is aimed at the management of complications as they arise. (medscape.com)

Tadalafil tablets are indicated for the treatment of erectile dysfunction (ED). (nih.gov)

Less invasive uterine-sparing procedures, such as myomectomy, are hence attractive alternatives, particularly for women of childbearing age who desire future pregnancy. (sls.org)

Lack of appropriate treatment leads to coronary artery aneurysms (CAA) in approximately 25% of cases. (rch.org.au)

Consideration should be given to the prevention of atherosclerosis and osteoporosis , because these are long-term consequences of SLE and its treatment. (medscape.com)

Since they are part of the immune system, can specifically bind to targeted cancer cells, and locally increase the concentration effect of the drug where it is needed, would significantly decrease the systemic side effects of chemotherapy (i.e. nausea, fatigue, pain, hair loss). (acsh.org)

As Wang explained, "docetaxel is a proven drug used in chemoradiotherapy, but it leads to many unwanted side effects on normal organs. (nanowerk.com)

The goal of renal nerve ablation is to achieve a reduction in sympathetic over-activity with the resultant effect of reducing systemic arterial blood pressure (BP), and mitigating resultant end-organ damage. (qmul.ac.uk)

it is administered in a doctor's office and only to the affected skin, not the entire body, thus sparing healthy skin from UV rays health risks. (bibalex.org)
it also improves the function of healthy organs such as the brain and muscles, having cytoprotective effects on them. (bibalex.org)
An additional, and very difficult problem, is drug delivery getting the most drug to the cancer while sparing healthy cells. (acsh.org)

9. History of organ transplant or bone marrow transplant, or planned organ transplant within 6 months following randomisation (including kidney transplant). (who.int)

Several trials also test escalating treatment strategies for non-cleared ctDNA following standard adjuvant chemotherapy. (rug.nl)
A Cochrane Database Systematic Review found no randomized controlled trials comparing these 2 treatments and concluded there was no evidence of a treatment advantage of cyclophosphamide. (medscape.com)
Such trials are also the primary way that progress is made in finding better approaches to treatment and cure. (swedish.org)

Radiofrequency ablation and stereotactic RT are potential alternative local treatment options for primary lung or bone metastases. (medscape.com)

For the lowest risk, small kidney masses that have not spread, we do active surveillance, which means these masses can be evaluated by watching closely over time and may never need treatment. (rogelcancercenter.org)
Enhanced cell potential film and to improve and slow organ aging (such as: kidney, gastrointestinal disorders) 3. (slimmingequipmentbody.com)

With a strong track record of proven efficacy, our commitment to rigorous research and development ensures healthcare providers have a reliable treatment option. (tajgenerics.com)

In the United States, the incidence of systemic sarcoidosis ranges from 5-40 per 100,000 population [5] . (aao.org)

This overall treatment approach should be familiar to neurologists who are accustomed to the evaluation and treatment of other autoimmune conditions such as multiple sclerosis, myasthenia gravis, or polymyositis. (medscape.com)
It's an approach that combines leading-edge treatment with the compassionate care Swedish is known for. (swedish.org)
We take a team approach to your sarcoma treatment because we know this offers the best success in controlling and curing cancer. (swedish.org)
A stepwise approach to the treatment of hypotension is recommended. (vin.com)
In addition to enabling a charitable approach to each novel's treatment of a controversial literary subject, Levinson's theory allows for the framing of each author's statement about rights as intentional and as constituting the central literary meaning. (lu.se)

Mycophenolate mofetil (Cellcept) was originally used a treatment to prevent rejection in organ transplantation. (albertarheumatology.com)

Acute GvHD is staged as follows: overall grade (skin-liver-gut) with each organ staged individually from a low of 1 to a high of 4. (wikipedia.org)

TransCode utilizes its TTX platform in the metastatic setting with the goal to improve treatment outcomes and enable long-term survival possibilities. (transcodetherapeutics.com)

Diseases1

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Lupus11

Diagnosis7

Toxicity6

Tumor8

Lungs7

Tumors8

Tissue8

Therapies11

Clinical12

Corticosteroids6

Nasolabial folds2

Medications4

Lymphatic system1

Immunosuppressive agents3

Kidneys1

Vascular resistance3

Vasculitis2

Autoimmune disease1

Symptoms10

Arterial wall1

Disease10

Patients16

Vital organs1

Severe2

Dose3

Infections1

Commonly1

Syndrome3

Radiation therapy1

Curative1

Manifestations1

Surgical2

Complications4

Dysfunction1

Invasive1

Aneurysms1

Prevention1

Fatigue1

Side effects1

Damage1

Healthy3

Transplant1

Trials3

Lung1

Kidney2

Efficacy1

Incidence1

Approach5

Transplantation1

Skin1

Improve treatment outcomes1