• allergen
  • The most common identifiable triggers of anaphylaxis would be food, insect venom or medication while less commonly by allergen such as natural rubber latex or physical factor such as exercise (Simons, 2006). (studymode.com)
  • Anaphylaxis is first initiated by the uptake of allergen by professional antigen presenting cells (APCs) which will present selected peptides on MHC class II molecule to naive T cells. (studymode.com)
  • Although allergen-induced systemic basophil degranulation was inhibited in an FcγRIIb-dependent manner, inhibition of local mast cell degranulation in tissues occurred independently of FcγRIIb. (rupress.org)
  • antibodies
  • In many individual, anaphylaxis is mediated by the expansion of T helper 2 cell (TH2-cell), a subset of T cells, together with isotype switching of B cells to generate IgE antibodies specific for common environment allergens (Holgate and Polosa, 2008). (studymode.com)
  • immune
  • It involves a coordinated and systemic mobilization response locally of various immune, endocrine and neurological mediators of acute inflammation. (wikipedia.org)
  • diseases
  • sporadic cases report of anaphylaxis were only published in 17th, 18th and 19th centuries and within the past four decades, the rates of allergic diseases have been increasing dramatically. (studymode.com)
  • disease
  • Similar to other helminths, L. sigmodontis induces systemic immunomodulation ( 5 - 7 ), and a previous study demonstrated that L. sigmodontis can inhibit the development of allergic disease when infection is established prior to allergic sensitization ( 8 ). (jimmunol.org)
  • History
  • Carrying an epinephrine autoinjector and identification regarding the condition is recommended in people with a history of anaphylaxis. (wikipedia.org)
  • muscle
  • The primary treatment of anaphylaxis is epinephrine injection into a muscle, intravenous fluids, and positioning the person flat. (wikipedia.org)