• Harmala alkaloids are classed as MAO-inhibiting beta -carbolines . (psychonautwiki.org)
  • The three most studied harmala alkaloids in the B. caapi vine are harmine , harmaline and tetrahydroharmine . (psychonautwiki.org)
  • Harmala alkaloids are RIMA's which selectively and reversibly inhibit the enzyme 'Monoamine Oxidase A' (MAO-A). Because of the reversibility and selectivity RIMAs are safer than MAOI's. (dmt-nexus.me)
  • Direct analysis of psychoactive tryptamine and harmala alkaloids in the Amazonian botanical medicine ayahuasca by liquid chromatography-electrospray ionization-tandem mass spectrometry. (dmt-nexus.me)
  • It is presently unclear whether harmine and harmaline are being chemically reduced to THH during the acidic process of decoction, or if THH is simply more stable than the other two harmala alkaloids, which may be lost through decomposition, or a combination of both processes. (dmt-nexus.me)
  • Traditional ayahuasca is made by brewing the MAOI-containing Banisteriopsis caapi vine with a DMT-containing plant, such as Psychotria viridis. (wikipedia.org)
  • Alkaloid Entheogen Ayahuasca Erowid: Ayahuasca A General Introduction to Ayahuasca Archived 2015-10-13 at the Wayback Machine Ott J. Ayahuasca Analogues: Pangaen Entheogens. (wikipedia.org)
  • Can one get an 'optimum' ayahuasca alkaloid content by messing with cooking time/storage? (dmt-nexus.me)
  • These two extracts (DMT and harmalas) can be combined, usually in pill form, to produce a sort of "pseudo-synthetic" version of ayahuasca, known as pharmahuasca. (the-nexian.me)
  • N,N-DMT and harmaline or harmine are typically used as components of pharmahuasca. (wikipedia.org)
  • The capsules with harmaline/harmine are swallowed first and the capsules containing DMT are taken 15 to 20 minutes later. (wikipedia.org)
  • A synthetic MAOI can be used in place of harmaline and harmine, although caution must be taken when choosing an MAOI. (wikipedia.org)
  • Active substances include the hallucinogen N-N-dimethyltryptamine and beta-carboline alkaloids such as harmine and harmaline. (cdc.gov)
  • Harmine and harmaline are selective and reversible inhibitors of monoamine oxidase A (MAO-A), while tetrahydroharmine is a weak serotonin reuptake inhibitor (SRI). (psychonautwiki.org)
  • This appears to occur to a significant degree for the changes seen in THH, harmine and harmaline levels between samples undergoing further heating to attain higher concentrations of the components (See Table 3). (dmt-nexus.me)
  • This phenomenon, an apparent acid-driven chemical reduction of harmine-to-harmaline-to-THH, has also been reported by Callaway et al. (dmt-nexus.me)
  • Interesting enough, recently I tested some black caapi vine, just methanol soak, and it didnt seem to have any detectable harmaline. (dmt-nexus.me)
  • When I tested an extraction from the same vine, it did have detectable harmaline. (dmt-nexus.me)
  • Of these, it most commonly consists of a DMT -containing plant source in combination with one that contains an MAOI or RIMA (typically sources like B. caapi vine or syrian rue ) to produce uniquely potent, sometimes medicinal, psychedelic effects. (psychonautwiki.org)
  • Made from the vine Banisteriopsis caapi and other plants, the exact ingredients can vary in depending on the location. (cdc.gov)
  • The average ratio of THH to harmine in the vegetals (traditional brews) was consistently near 1:1, from all sources (table 2), while this ratio was closer to 1:5 in a large survey of source plant material. (dmt-nexus.me)
  • Perhaps there was a predator for which muscarine, psilocybin , mescaline , or other natural psychedelic alkaloids were well-equipped to defend. (tripsitter.com)
  • For some insects and animals, the alkaloids we enjoy from plants and fungi may have the potential to kill. (tripsitter.com)
  • Active substances include the hallucinogen N-N-dimethyltryptamine and beta-carboline alkaloids such as harmine and harmaline. (cdc.gov)
  • During their "experiments" at the tiny mission site of La Chorrera, combining the beta-carboline alkaloids deriving from the Banisteriopsis caapi (ayahuasca) vine with the psilocybin-containing mushrooms that they found plentifully in the surrounding pastures, it was Dennis who seems to have recalled an article by Harner, from which he recalled mention of a magical fluid that shamans produced from their mouths. (terencemckennaarchives.com)