Thiourea is a reagent in organic synthesis. (wikipedia.org)
For example, mercury sulfide forms when mercuric salts in aqueous solution are treated with thiourea: Hg2+ + SC(NH2)2 + H2O → HgS + OC(NH2)2 + 2 H+ These sulfiding reactions, which have been applied to the synthesis of many metal sulfides, require water and typically some heating. (wikipedia.org)
InhA enzyme was selected as it includes an extremely hydrophobic site that favorably interacts Ipratropium bromide supplier with thioamide or thiourea moieties [25]. (bio-cavagnou.info)
InhA enzyme was particular based on its hydrophobic Ipratropium bromide supplier properties that favorably connect to thioamide or thiourea moieties [25]. (bio-cavagnou.info)
Thiourea is a reagent in organic synthesis, a special branch of chemical synthesis, and is concerned with the construction of organic compounds via organic reactions. (yuanfarchemical.com)
Amides5
The amides I and IV-VI were transformed by treatment with phosphorus pentasulfide in pyridine to the thioamides X-XIII . (cas.cz)
The oily or crystalline bases of the amino amides or thioamides were mostly transformed to crystalline salts and characterized by spectra. (cas.cz)
Rapid synthesis of amides and lactams. (ensicaen.fr)
Dr. Murai discovered that sulfur isologues of amides and esters, i.e., thioamides and thioesters, in which a C=S group is present, exhibit unique nucleophilicity and electrophilicity which were not observed for amides and esters, fully utilized those properties, and established unprecedented carbon?carbon bond-forming reactions. (or.jp)
Synthesis and separation of diastereomeric N-(1-phenylethyl)amides of inherently chiral hydroxydibenzoyloxy-calix[4]arene acetic acids (2022) Chirality, 34(11),pp.1466-1471.https://www.scopus.com/inward/record.uri?eid=2-s2.0 85136719766&doi=10.1002%2fchir.23503&partnerID=40&md5=21fd40d69ba3d6b5c9bc10e56bcd406. (org.ua)
20191
Celik İ, Ayhan-Kılcıgil G, Guven B et al (2019) Design, synthesis and docking studies of benzimidazole derivatives as potential EGFR inhibitors. (dntb.gov.ua)
Nanofiber membranes1
Poly(vinyl alcohol)/maleic anhydride/acryloyl thioamide monomer (PVA/MA/ATM) nanofiber membranes (NFm) were synthesized by a combination of UV radiation and an electrospinning technique. (itu.edu.tr)
Compounds8
The thesis herein describes the synthesis and characterization of compounds designed to be utilized as acceptor molecules in non-covalent interactions. (jyu.fi)
The synthesis of these compounds has been patented because they are of applied interest. (revistadechimie.ro)
The researches performed in the Departement of Organic Chemistry concerning the synthesis of 3,5-disubstituted dithiazolium salts have been extended about the compounds substituted with stiryl radicals and vinylen-heterocycles [8-12]. (revistadechimie.ro)
In this paper we have proposed a comparative study on the synthesis of the 3,5-disubstituted-1,2,4-dithiazolium tribromides and triiodides in order to establish the optimal reaction conditions and to establish the structures of the new synthetised compounds. (revistadechimie.ro)
Although sulfur dioxide (SO 2 ) has been used as a reagent for organic chemistry for more than one hundred years, being endowed with quite a distinct and varied reactivity profile, which allows the synthesis of a large range of compounds, its notorious toxicity as well as its gaseous state have impeded its frequent utilization by chemists. (unistra.fr)
Reactions of secondary thioamides with BuLi generate carbanions adjacent to the nitrogen atom, and various electrophiles, including alkyl halides, carbonyl compounds, and oxiranes, were selectively incorporated into the carbanion centers. (or.jp)
Dr. Murai fully utilized the new reactions using thioformamides and thioamides presented above and created fluorescent compounds with unique skeletons and made these compounds express various functionalities. (or.jp)
In addition, a series of thiazole derivatives was synthesized by reaction of thioamide 3 with a number of α-halo compounds, namely, 3-chloropentane-2,4-dione ( 8 ) or 2-chloro-3-oxo- N -phenyl butanamide ( 10 ) phenacyl bromide 12 ethyl chloroacetate ( 14 ) in EtOH in the presence of triethylamine. (biomedcentral.com)
20181
Akhtar MJ, Khan AA, Ali Z et al (2018) Synthesis of stable benzimidazole derivatives bearing pyrazole as anticancer and EGFR receptor inhibitors. (dntb.gov.ua)
Alkyl1
Christian Wolf of Georgetown University showed that LiI converted an alkyl fluoride 3 to the alkyl iodide 4 ( Synthesis 2022 , 54 , 4320. (organic-chemistry.org)
20172
On February 10th, 2017 Prof. Alison J. Frontier (University of Rochester, New York) will talk about "Stereocontrolled Reactions for Complex Molecule Synthesis" in a lecture sponsored by Thieme Chemistry. (thieme.de)
Everyone is invited to attend the SYNTHESIS-SYNLETT Lecture at Queen's University in Kingston on February 10th, 2017! (thieme.de)
Chemistry2
This highly active research field is made up of a diverse community, with research ranging from organometallic and materials chemistry (development of new photocatalysts) to mechanistic and synthetic organic (novel transformations and syntheses) to chemical engineering (improved reactors and processes). (beilstein-journals.org)
Professor Heathcock is well known for his accomplishments in the synthesis of complex polycyclic natural products and for his contributions to the chemistry community. (academicinfluence.com)
Biological7
Research Regarding Synthesis and Biological Activity of 1,2,4-dithiazole-3,5-disubstituted Salts. (revistadechimie.ro)
Research expertise in the group includes amino acid and peptide synthesis, liposome technology and techniques for studying biological membranes, including surface tensiometry, calorimetry, x-ray scattering, optical microscopy and mass spectrometry. (dur.ac.uk)
Aliwaini S, Thaher BA, Al-masri I et al (2021) Design, synthesis and biological evaluation of novel pyrazolo[1,2,4]triazolopyrimidine derivatives as potential anticancer agents. (dntb.gov.ua)
It covers all fields of scientific endeavor that involve organic synthesis, e.g. catalysis, organometallic, medicinal and biological, but also related disciplines. (thieme.de)
The current research is directed towards the functionalisation of the original cytisine and synthesis of analogues for biological assays. (ensicaen.fr)
In Chapter III, a new and general design strategy was described for increasing the rate, efficiency, and selectivity of H2S liberation from thioamide-based donors through intramolecular nucleophilic assistance, triggered by a specific biological stimulus. (wfu.edu)
Importantly, we predict this general scaffold can be modified to access a wide variety of thioamide-based donors that are selectively responsive to various biological stimuli. (wfu.edu)
Analogues1
The synthesis and reactivity of fully protected thioamide analogues of asparagine and glutamine are described. (figshare.com)
Organic2
There are multiple laboratory techniques available for the organic synthesis of thiazoles, with the most notable being the Hantzsch thiazole synthesis, which involves a reaction between haloketones and thioamides. (ambeed.com)
Thioureas belong to thioamides, a functional group with the general structure R-CS-NR′R″, where R, R′, and R″ are organic groups. (yuanfarchemical.com)
Antithyroid2
Similarly, these drugs can be attempted in cases of intolerance to other antithyroid drugs, e.g. thioamides, when can not be applied ablative measures. (endocrine-abstracts.org)
Liver function test results should be obtained to monitor for liver toxicity caused by thioamides (antithyroid medications). (medscape.com)
20221
Keyume Ablajan of Xinjiang University showed that activation of the hydrazide 25 with iodine gave an intermediate that coupled with aniline, leading to the amide 26 ( Synthesis 2022 , 54 , 4353. (organic-chemistry.org)
20201
AboulWafa OM, Daabees HMG, Badawi WA (2020) 2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study. (dntb.gov.ua)
Derivatives6
Also described are the preparations of thioamide derivatives of phenylalanine. (figshare.com)
The utility of these amino acid derivatives for solid-phase peptide synthesis is discussed. (figshare.com)
Thus, methodological approaches for cytisine radiolabelling with carbon-11 (half-life: 20 min) and synthesis of fluorinated derivatives including labelled with fluorine-18 (half-life: 110 min) have been developed. (ensicaen.fr)
Synthesis of substituted cytisine derivatives and labelling with fluorine-18. (ensicaen.fr)
In addition, thioamide 3 was used as starting material for preparation of a new series of thiadiazole derivatives via its reaction with hydrazonoyl chlorides 5a - c in dioxane using triethylamines as catalyst. (biomedcentral.com)
Treatment of thioamide derivative 3 with the appropriate hydrazonoyl halides of type 5a - c in refluxing EtOH containing TEA gave the corresponding thiadiazole derivatives 7a - c (Scheme 2 ). (biomedcentral.com)
Peptides2
Solid-phase peptide synthesis and protein semi-synthesis are powerful methods for site-specific modification of peptides and proteins. (bvsalud.org)
We describe protocols using these techniques for the syntheses of peptides and proteins bearing glutamate arginylation (EArg) at specific sites. (bvsalud.org)
46. Stereochemistry of the Michael addition of N,N-disubstituted amide and thioamide enolates to .alpha. (academicinfluence.com)
Membranes1
His current projects are concerned with the design, synthesis, and characterization of functional porous polymeric materials with various porosity scales (membranes, nanoporous, macroporous, doubly porous). (hal.science)
Substitution1
Thioamide substitution influences hydrogen bond and n → π ∗ interactions involved in the conformational stability of protein secondary structures and oligopeptides. (rcsb.org)
Bioactive1
Open up in another screen Fig.?1 Second line antituberculosis pro-drugs For the above-mentioned reasons so when an integral part of our curiosity about the synthesis and testing of potentially bioactive materials [20C24], we herein, survey the formation of some novel enoyl reductase InhA, to anticipate their feasible mode of action. (bio-cavagnou.info)
Characterization1
This thesis describes the design, synthesis and characterization of supramolecular halogen-bonded capsules and cages from multivalent ligands. (jyu.fi)
Nitrogen1
With heteroaryl disulfides, the NHC-borane in the primary NHC-boryl sulfide product migrates from sulfur to nitrogen to give new products with a thioamide substructure. (unistra.fr)
Reaction1
Specifically, in this chapter we demonstrated that both disulfide- and diselenide-linked thioamides are responsive to biologically relevant concentrations of glutathione and release H2S via a cyclization reaction that notably enhances the rate and efficiency of sulfide delivery in both buffer and live human cells. (wfu.edu)
Chemical1
SynOpen is an international open access journal reporting current research results in chemical synthesis. (thieme.de)
Application1
Synthesis of g-C 3 N 4 by thermal heating of urea and application to photocatalytic CO 2 reduction with. (beilstein-journals.org)
Series1
In addition, we identified an ROS-activated, self-reporting donor from this series, which stems from its concurrent synthesis of a benzoxazole-based fluorophore alongside its H2S delivery. (wfu.edu)
Total1
Stereoselective total synthesis of the guaiazulenic sesquiterpenoids .alpha. (academicinfluence.com)
Current1
Current work centres around the synthesis and exploitation of labelled lipids and sterols. (dur.ac.uk)
Treatment1
Taking into account the recommended short duration of the therapy with perchlorates (not excee-ding 1 month) and lacking the possibilities for other efficient and durable conservative treatment (both pa-tients presented Hashitoxicosis aggravated through iodine intake, and had thioamide-intolerance), we indicated thyroidectomy after obtaining euthyroidism with perchlorates. (endocrine-abstracts.org)
Control1
A superior class of reagents for control of Cram's rule stereoselection in synthesis of erythro-.alpha. (academicinfluence.com)
Main1
The main effect shown by isoxyl is inhibition of synthesis of tuberculostearic and oleic acid which is directly related to the effect shown by a drug. (microbenotes.com)