• D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. (medchemexpress.com)
  • D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. (medchemexpress.com)
  • Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. (bertin-bioreagent.com)
  • Antioxidant characterization of soy derived products in vitro and the effect of a soy diet on peripheral markers of oxidative stress in a heart disease model J . Canadian Journal of Physiology and Pharmacology 2012 90 8 1095-1103. (paperonce.org)
  • The rats were then given D-galactosamine, a potent liver toxin that interferes with cell synthesis and results in cell death. (thewellnesscsi.com)
  • It is suggested that the cell-wall process described represents an excretory mechanism of V. cholerae , and the nature of the products released by the young vibrios and their probable relation with cholera toxin is discussed. (microbiologyresearch.org)
  • Synthetic studies on bioactive compounds are described, involving phytotoxins (tobacco wildfire disease toxin tabtoxinine-β-lactam and rice blast disease toxin pyricuol) a glutarimide antibiotic (actiketal) black vomit toxin (gizzerosine) and marine products (antifeedant pteroenone and serinol compound didemniserinolipid). (go.jp)
  • Drop fat intake to 10 percent or so, but since that's a bit too much of a calorie deficit without proper supplementation, bump up your carbs to 50 to 60 percent of total calories, as they're the substrate for hexosamine synthesis (more on that later). (ironmanmagazine.com)
  • Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure[1][2]. (medchemexpress.com)
  • 63342} It reduces hepatic necrosis and increases in serum TNF-α, IL-6, and chemokine (C-C motif) ligand 2 (CCL2) levels in a mouse model of LPS/D-galactosamine-induced acute liver failure when administered at doses of 15, 30, or 60 mg/kg. (bertin-bioreagent.com)
  • Molecular strategies for the synthesis of A-glycosidic linkages have been reviewed for over 30 years. (endlessorchard.com)
  • Although the mechanisms responsible for fatty liver are not fully elucidated, an increased delivery and transport of FFAs into the liver, and augmented hepatic fatty acid synthesis are likely to play a significant role in the pathogenesis of NAFLD. (spandidos-publications.com)
  • Carbohydrates are known as the main natural products of life activities. (springeropen.com)
  • The use of multiple names for some of the genes involved in capsule synthesis, combined with the need for rapid diagnosis of serogroups commonly associated with invasive meningococcal disease, prompted a requirement for a consistent approach to the nomenclature of capsule genes. (cdc.gov)
  • The other aim was to expand the work of Crompton & Ward (1967 a ) , who found that lactic and succinic acids were the main excretory products from the carbohydrate metabolism of P. minutus , by analyzing extracts of the worms for other metabolites originating from glucose. (biologists.com)
  • Hence, the present study was designed to examine the effect of T. chebula on erythrocyte oxidation products level, antioxidant status, membrane ATPases and glycoproteins in aged rats compared with young rats. (scialert.net)
  • Short-chain fatty acids (SCFAs) are metabolic products of oral bacteria including A. oris and regulate pH in dental plaques. (biomedcentral.com)
  • Grape seed extract is a natural product, with anti-inflammatory and anti-proliferative effects. (medchemexpress.com)
  • Leptin is signaled by fat stores as well as by nutrient intake'specifically, various foodstuffs and their metabolic by-products. (ironmanmagazine.com)
  • Two of the mutants were capable of growth in media supplemented only with δ -aminolaevulinic acid, the first intermediate of porphyrin synthesis. (microbiologyresearch.org)
  • One of the pentacyclic triterpenes is 2α,3β,19α-trihydroxyurs-2-en-28-oic acid known as tormentic acid (TA). (encyclopedia.pub)
  • Subscribe above to receive our eNews, featuring scientific research, new products, and exclusive promotions. (tcichemicals.com)
  • This study was performed to identify the carrier proteoglycan (PG) and the sulfotransferase gene involved in synthesis of the surface P-selectin-reactive CS-GAGs in human breast cancer cells with high metastatic capacity, as well as to determine a direct role for CS-GAGs in metastatic spread. (biomedcentral.com)
  • Control experiments demonstrate that, for this transformation, the silanol is not particularly privileged, and a variety of protecting groups on the alcohol (including other silicon protecting groups, benzyl ethers, and MOM ethers) are compatible with product formation. (ku.edu)
  • Besides being an important component in glycoconjugate synthesis, the benefits of such molecules have also been the focus of intensive research due to their roles in critical biological processes and potential for use as therapeutics.A common problem while generating a class diagram is the absence of the necessary information to properly fill out the diagram. (endlessorchard.com)
  • Natural Product Research. (cu.edu.eg)
  • Kinetics of mucopolysaccharide and glycoprotein synthesis by chick embryo chondrocytes: effect of D-glucose concentration in the culture medium. (unclesarm.com)
  • The latest news, tips, and product releases delivered conveniently to your inbox. (vectorlabs.com)
  • Finally, some so-called bad fats, such as those found in eggs and meat, are precursors for prostaglandins, which mediate inflammation-type anabolic responses and increases in protein synthesis. (ironmanmagazine.com)
  • Please let us know what you think of our products and services. (mdpi.com)
  • The reactions scale well, and the products serve as synthons for ring-opening reactions. (ku.edu)
  • While the machine is located at the Structural Biology Laboratory in Heslington, it will serve all of Britain's evolving glycan synthesis cluster. (glycouniverse.com)