• inflammatory
  • Background Manual outlining of the synovial membrane on MR images in inflammatory joint diseases is too time consuming for clinical use. (bmj.com)
  • Objectives The purpose was to introduce a less time-consuming stereologic method for measuring synovial volume by MRI in inflammatory joint diseases. (bmj.com)
  • Objectives To identify the differentially expressed genes between the inflammatory (I) and normal/reactive (N/R) synovial areas using a unique ex vivo culture model and to investigate the genetic modulatory effects of CS in this model. (bmj.com)
  • Conclusions Our work demonstrates the differential gene expression profile between paired inflammatory and normal/reactive areas of synovial membrane as well as the modulatory effects of CS on gene expression in the inflammatory areas, especially regarding genes involved in both angiogenesis and cell migration. (bmj.com)
  • Dryll A, Lansaman J, Cazalis P, Peltier AP, DeSeze S (1977) Light and electron microscopy study of capillaries in normal and inflammatory human synovial membrane. (springer.com)
  • tissue
  • Conclusions There are significant differences in the histomorphometric features of synovial tissue between patient subgroups. (bmj.com)
  • Methods
  • Methods 42 patients with newly diagnosed untreated JIA underwent synovial biopsy before the administration of steroids or disease-modifying antirheumatic drugs. (bmj.com)
  • found
  • A significant correlation between manual and stereologic estimations of synovial volumes was found (Spearman rho = 0.71, P = 0.002). (bmj.com)
  • study
  • This study of the synovial membrane characterises the immunohistochemical features in early untreated, newly diagnosed JIA and compares findings with disease subgroup at 2 years. (bmj.com)
  • cells
  • Double-staining techniques with mouse monoclonal antibodies against cell subset markers in five RA synovial membranes showed that up to 13% of T-cells and 19% of antibody-producing cells stained for IL-6. (ox.ac.uk)
  • provide
  • Conclusion Stereologic volume estimation can provide measures of synovial volumes comparable to the manual outlining method and is less time-consuming. (bmj.com)
  • areas
  • The synovial membrane was dissected and SC from N/R and I areas cultured separately for a period of 7 days with or without highly purified bovine CS (200 µg/ml, Bioibérica S.A., Barcelona, Spain). (bmj.com)