Hereditary Breast and Ovarian Cancer SyndromeOvarian NeoplasmsGenes, BRCA1SyndromeBRCA2 ProteinBRCA1 ProteinGenes, BRCA2Neoplastic Syndromes, HereditaryGenetic TestingGenetic CounselingGerm-Line MutationBreast NeoplasmsPedigreeGenes, DominantGenetic Predisposition to DiseaseMutationBreastHeterozygotePolycystic Kidney, Autosomal DominantDNA Mutational AnalysisNeoplasm ProteinsFamily HealthFounder EffectNeoplasms, Glandular and EpithelialGenetic LinkageBreast Neoplasms, MaleAge of OnsetColorectal Neoplasms, Hereditary NonpolyposisDown SyndromeMetabolic Syndrome XGene Expression Regulation, NeoplasticRisk Factorsvon Hippel-Lindau DiseasePhenotypeExonsCell Line, TumorGenotypeHamartoma Syndrome, MultipleCarcinoma, Ductal, BreastDNA, NeoplasmMastectomyFamilyMutation, MissenseBreast Diseases