HN - 2011 MH - 22q11 Deletion Syndrome UI - D058165 MN - C5.660.207.103 MN - C14.240.400.21 MN - C14.280.400.44 MN - C15.604.451.249 MN - C16.131.77.19 MN - C16.131.240.400.21 MN - C16.131.260.19 MN - C16.131.482.249 MN - C16.131.621.207.103 MN - C16.320.180.19 MN - C19.642.482.500 MS - Condition with a variable constellation of phenotypes due to deletion polymorphisms at chromosome location 22q11. (nih.gov)
These oral clefts are typically caused by chromosome abnormalities and defined monogenic syndromes. (msdmanuals.com)
Clinical1
The clinical and therapeutic aspects in Sotos' syndrome]. (nih.gov)
Oral3
Syndromic oral clefts are those present in patients with recognized congenital syndromes or with multiple congenital anomalies. (msdmanuals.com)
She was reviewed under the joint care of the Oral and Maxillofacial Surgery and Otolaryngology Teams. (hindawi.com)
She was then referred to the joint care of the Oral and Maxillofacial Surgery and Otolaryngology teams. (hindawi.com)
Typically1
Silver-Russell Syndrome (SRS) is typically characterized by asymmetric gestational growth restriction resulting in affected individuals being born small for gestational age, with relative macrocephaly at birth (head circumference ≥1.5 SD above birth weight and/or length), prominent forehead usually with frontal bossing, and frequently body asymmetry. (nih.gov)
Multiple3
25. [Maxillofacial and dental abnormalities in some multiple abnormality syndromes. (nih.gov)
39. [Maxillofacial and dental anomalies in multiple-abnormality syndromes. (nih.gov)
They may involve only a single, specific site (eg, cleft lip, cleft palate, clubfoot) or be part of a syndrome of multiple. (msdmanuals.com)
Growth4
33. Excessive head growth in early infancy: a feature of Sotos' syndrome. (nih.gov)
35. Growth hormone hypersecretion in Sotos' syndrome? (nih.gov)
Overview of Congenital Craniofacial Abnormalities Congenital craniofacial abnormalities are a group of defects caused by abnormal growth and/or development of the head and facial soft-tissue structures and/or bones. (msdmanuals.com)
Goals of treatment are to ensure normal feeding, speech, and maxillofacial growth and to avoid formation of fistulas. (msdmanuals.com)
Early1
Early treatment, pending surgical repair, depends on the specific abnormality but may include specially designed bottle nipples (to facilitate flow), dental appliances (to occlude the cleft so suckling can occur), a feeder that can be squeezed to deliver formula, taping, and an artificial palate molded to the child's own palate. (msdmanuals.com)