• Ocular
  • Clonus Migraine Epilepsy Pathologic nystagmus Physiologic nystagmus Psychogenic non-epileptic seizures Saccade Ocular flutter Wong A (2007). (wikipedia.org)
  • The consulting thoracic surgeon was hesitant to biopsy the lesion due to its small size, but given the concern that the ocular flutter was a manifestion of a paraneoplastic syndrome, he performed a fine needle aspiration of the lesion that yielded malignant cells. (harvard.edu)
  • Albinism is classified into two subtypes, non-syndromic albinism, with symptoms restricted to impaired melanin biosynthesis (hypopigmentation of skin and hair and ocular changes such as reduced pigmentation of the iris, nystagmus, impaired visual acuity, and foveal hypoplasia), and syndromic albinism, which displays various non-pigmentary symptoms including bleeding diathesis, lung fibrosis, and immunodeficiency. (springer.com)
  • Consecutive patients with AVS (vertigo, nystagmus, nausea/vomiting, head-motion intolerance, unsteady gait) with ≥1 stroke risk factor underwent structured examination, including horizontal head impulse test of vestibulo-ocular reflex function, observation of nystagmus in different gaze positions, and prism cross-cover test of ocular alignment. (ahajournals.org)
  • The presence of normal horizontal head impulse test, direction-changing nystagmus in eccentric gaze, or skew deviation (vertical ocular misalignment) was 100% sensitive and 96% specific for stroke. (ahajournals.org)
  • Genes
  • It is caused by pathologic variants of genes that are associated with melanin synthesis, melanocyte differentiation/migration, or membrane trafficking. (springer.com)
  • disorders
  • There is no cure for some kinds of eye movement disorders, such as most kinds of nystagmus. (medlineplus.gov)
  • The disorders include attention-deficit/hyperactivity disorder, oppositional defiant disorder, nonspecific disruptive disorder, autism spectrum disorders, and stereotypical movement disorder in prepubertal children with Down syndrome and depressive illness, obsessive-compulsive disorder, and psychosislike disorder in adolescents and adults with Down syndrome. (medscape.com)
  • The presence or absence of nystagmus is often used in the diagnosis of a variety of neurological and visual disorders. (fpnotebook.com)
  • Cogenital Vermian Hypoplasia (CVH) in COACH syndrome was accompanied by elongation of the superior cerebellar peduncles and a deep interpeduncular fossa, all features that constitute the molar tooth sign (MTS), the key feature of Joubert syndrome and related disorders (JSRD). (wikipedia.org)
  • pathology
  • The diagnosis is based on presenting signs and symptoms, the absence of external or middle ear pathology on otoscopic examination, 512-Hz tuning forks lateralizing to the more severely affected ear, nystagmus triggered by loud, low-frequency sound stimuli or a Valsalva maneuver, and computed tomography imaging confirming a bony defect of the semicircular canal. (lww.com)
  • Nystagmus can be caused by subsequent foveation of moving objects, pathology, sustained rotation or substance use. (wikipedia.org)
  • clinically
  • Nystagmus can be clinically investigated by using a number of non-invasive standard tests. (wikipedia.org)
  • The condition begins in 85% of cases as a clinically isolated syndrome (CIS) over a number of days with 45% having motor or sensory problems, 20% having optic neuritis, and 10% having symptoms related to brainstem dysfunction, while the remaining 25% have more than one of the previous difficulties. (wikipedia.org)
  • Causes
  • contradictory] Pathological nystagmus generally causes a degree of vision impairment, although the severity of such impairment varies widely. (wikipedia.org)
  • dysfunction
  • Jerk nystagmus has a slow phase in one direction followed by a corrective fast phase in the opposite direction, and is usually caused by central or peripheral vestibular dysfunction. (fpnotebook.com)
  • disorder
  • Angelman Syndrome (Happy Puppet Syndrome): AS is a neurodevelopmental disorder caused by loss of paternally derived gene(s) on chromosome 15. (rettsyndrome.org)
  • Most children with Down syndrome do not have a coexisting psychiatric or behavioral disorder. (medscape.com)
  • The vermis hypoplasia falls in a spectrum of mid-hindbrain malformation called the molar tooth sign (MTS), making COACH a Joubert syndrome related disorder (JSRD) due to mutation in the gene TMEM67 in majority of cases. (wikipedia.org)
  • visual
  • The hypothesis is that nystagmus and associated visual symptoms will be improved while on the Azopt compared to the placebo. (clinicaltrials.gov)
  • Pendular nystagmus features oscillations that are of equal velocity in both directions and this condition is often associated with visual loss early in life. (fpnotebook.com)
  • In medicine, the presence of nystagmus can be benign, or it can indicate an underlying visual or neurological problem. (wikipedia.org)
  • problems with speech or swallowing, visual problems (nystagmus, optic neuritis or double vision), feeling tired, acute or chronic pain, and bladder and bowel difficulties, among others. (wikipedia.org)
  • Cushing
  • Cushing syndrome (cortisol excess, leading to hyperglycemia, hypokalemia, hypertension, central obesity, moon facies) may result from ectopic production of ACTH or ACTH-like molecules, most often with small cell cancer of the lung. (merckmanuals.com)
  • occur
  • The pathologic process, or first event, by which SCD may occur includes congenital bone-thinning over the superior semicircular canal with low-lying skull base (arcuate eminence defect) or a close anatomic relationship between the superior petrosal sinus and the medial limb of the superior semicircular canal. (lww.com)
  • semicircular
  • Pathological nystagmus is the result of damage to one or more components of the vestibular system, including the semicircular canals, otolith organs, and the vestibulocerebellum. (wikipedia.org)
  • drugs
  • Successful treatment is best obtained by controlling the underlying cancer, but some symptoms can be controlled with specific drugs (eg, cyproheptadine or somatostatin analogs for carcinoid syndrome, bisphosphonates and corticosteroids for hypercalcemia). (merckmanuals.com)
  • Previously considered untreatable, in recent years several pharmaceutical drugs have been identified for treatment of nystagmus. (wikipedia.org)
  • movement
  • Over the past forty years, objective eye-movement-recording techniques have been applied to the study of nystagmus, and the results have led to a greater accuracy and understanding of the condition. (wikipedia.org)
  • often
  • Most newborns with this syndrome are of normal birth weight and length, but will often slow within the first year. (wikipedia.org)
  • condition
  • These peculiar symptoms can be associated with an unusual condition of the inner ear called superior canal dehiscence (SCD) syndrome. (lww.com)
  • An alternative name of the condition, LEOPARD syndrome, is a mnemonic, originally coined in 1969, as the condition is characterized by some of the following seven conditions, the first letters of which spell LEOPARD, along with the characteristic "freckling" of the skin, caused by the lentigines that is reminiscent of the large cat. (wikipedia.org)